Dog Ureter Research Articles

Studies on the regulatory mechanism of peristalsis in the isolated dog ureter

Using the isolated dog ureter or kidney-ureter preparations, the effects of intraluminal perfusion pressure, and the possible influence of autonomic nervous system on the ureteral motility were examined.Normal peristaltic activity was markedly changed in its rhythm, contraction force and conduction, by intraluminal pressure gradient and sometimes antiperistalsis was observed by moderate decrease in intraluminal pressure. Electrical stimulation on the renal hilus with which we attempted to stimulate nerve fibers, failed to find any change in peristaltic activity. Furthermore, TTX, both adrenergic and cholinergic blocking agents did not show any effect on the peristaltic activity and intraluminal pressure-peristalsis relationship.By the histochemical examinations both adrenergic and cholinergic fibers in the ureter were observed to be extremely few comparing to that in was deferens, and ganglion cell could not be found.From the results, it was concluded that dog ureteral peristalsis might be mainly regulated by hydrauric factor, especially gradient of intraluminal pressure, and might be scarcely regulated by autonomic nervous system.

DETERMINATION OF TRANSPORTED URETERIC VOLUME IN DOGS BY CINEROENTGENOLOGIC ANALYSIS

The kidney pelves of 4 mongrel dogs were infused with contrast media at known constant rates through nephrostomy tubes. Cine studies were carried out as boluses formed at the ureteral cone. From these studies, the average length, average area, and average of the boluses were determined for various flow rates. Each was multiplied by the observed peristaltic frequency to produce length, area, and volume factors. Urinary excretion was determined for each dog and added to the infusion rate to estimate total excretion. Statistical analysis of results revealed very good correlation with true excretion and only small differences in the usefulness of each factor to enable prediction of total excretion. Area and volume factors are slightly better than length factors. Since the area factor is more simply derived, it is the method of choice for the small boluses occurring in the dog's ureter. The accuracy of the method is such that it would appear best suited to serve as a screening method, recognizing as...

EFFECT OF URETERAL BLOCKADE ON RENAL BLOOD FLOW AND URINARY CONCENTRATING ABILITY.

Complete blockade of the ureter in dogs subjected to saline loading (0.85–10.0% NaCl) resulted in an increase in total renal blood during the period of blockade which appeared to be related to the antecedent diuresis and increment in ureteral pressure. This was accompanied by a progressive decrease in extraction of para-aminohippurate (PAH) and a greater decrease in creatinine extraction. The change in Epah showed a close inverse correlation to the change in renal blood flow (RBF). This afforded a possible explanation for the increment in RBF, for the increased perfusion of vascular circuits of the A-V communicating type would account for such a correlation. Evidence was supplied which suggested that such pathways involved the medullary vascular circuits. This was based on the observation that the concentrating ability of the kidney was impaired by the period of occlusion. The most likely mechanism for this would be maintained (or increased) vascular perfusion of the vasa recta system, in the face of markedly curtailed glomerular filtration, conditions resulting from ureteral blockade.

The behaviour of the intact ureter in dogs, rabbits and rats.

The Journal of PhysiologyVolume 129, Issue 3 p. 436-447 ArticleFree Access The behaviour of the intact ureter in dogs, rabbits and rats D. W. Gould, D. W. GouldSearch for more papers by this authorA. C. L. Hsieh, A. C. L. HsiehSearch for more papers by this authorL. F. Tinckler, L. F. TincklerSearch for more papers by this author D. W. Gould, D. W. GouldSearch for more papers by this authorA. C. L. Hsieh, A. C. L. HsiehSearch for more papers by this authorL. F. Tinckler, L. F. TincklerSearch for more papers by this author First published: 28 September 1955 https://doi.org/10.1113/jphysiol.1955.sp005368Citations: 13AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume129, Issue3September 28, 1955Pages 436-447 RelatedInformation

Histological Examination of the Regeneration of the Ureter in Dogs After Intubated Ureterotomy

Histological Examination of the Regeneration of the Ureter in Dogs After Intubated Ureterotomy

Experimental repair of ureters by polyethylene tubing and ureteral and vessel grafts.

OCCASIONALLY the surgeon is confronted with the vexing problem of restoring a gap in the ureter. If the defect is extensive, he must be content with a choice of either nephrectomy, cutaneous ureterostomy, uterosigmoidostomy, or ureteroureteral anastomosis. 1 A defect of the distal ureter near the bladder can be reconstructed by utilizing a full-thickness flap of bladder wall fashioned into a tube. 2 Experimentally, segments of the ureter have been successfully bridged by the substitution of a loop of terminal ileum. 3 The transplantation of dog ureters into the duodenum caused death from electrolyte imbalance. 4 Vitallium 5 and fascial transplants 6 have been used as a direct method of reconstructing ureteral defects. Vitallium tubes are reported to be tolerated in the urinary tract of the dog for as long as nine months without causing encrustrations. End-to-end anastomosis of the ureter over a straight Vitallium tube healed per primam in

The vascularisation and healing of the transplanted ureter in dogs.

The vascularisation and healing of the transplanted ureter in dogs.

Intubated Ureterotomy: Experimental Work and Clinical Results

Intubated Ureterotomy: Experimental Work and Clinical Results

An Experimental Study of the Action of Sodium Iodide on Excised and Intact Ureters of Dogs

No AccessJournal of Urology1 Apr 1930An Experimental Study of the Action of Sodium Iodide on Excised and Intact Ureters of Dogs1 Harry R. Trattner, Herbert B. Wright, and O.W. Barlow Harry R. TrattnerHarry R. Trattner More articles by this author , Herbert B. WrightHerbert B. Wright More articles by this author , and O.W. BarlowO.W. Barlow More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)72980-1AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail © 1930 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByWhisenand J and Moore V (2018) Hydrodynamics of Upper Urinary Tract After Mucosal Ureterosigmoidostomy: Case ReportJournal of Urology, VOL. 65, NO. 4, (564-570), Online publication date: 1-Apr-1951.Lawson J and Tomlinson W (2018) Observations on the Dynamics of Acute Urinary Retention in the DogJournal of Urology, VOL. 66, NO. 5, (678-685), Online publication date: 1-Nov-1951.Rolnick H and Singer P (2018) Ffects of Overdistention of the Renal Pelvis and Ureter: A Study on Pyelovenous BackflowJournal of Urology, VOL. 57, NO. 5, (834-838), Online publication date: 1-May-1947.Trattner H and Walzak B (2018) Studies Concerning Effects of Calcium on the Urinary TractJournal of Urology, VOL. 52, NO. 4, (357-373), Online publication date: 1-Oct-1944. Volume 23Issue 4April 1930Page: 441-462 Advertisement Copyright & Permissions© 1930 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Harry R. Trattner More articles by this author Herbert B. Wright More articles by this author O.W. Barlow More articles by this author Expand All Advertisement PDF DownloadLoading ...

Ephedrine Hydrochloride on the Excised Ureter of the Dog

Conclusion1. Ephedrine hydrochloride is mainly stimulant to the excised ureter of the dog. 2. The qualitative effect of ephedrine hydrochloride on the dog's ureter closely resembles that produced by epinephrine. 3. Ephedrine hydrochloride and epinephrine differ widely quantitatively when measured by the reaction of the surviving ureter to these agents, the latter being in some experiments about 200 times as stimulant as ephedrine. 4. The depression of the dog's ureter which appears after the use of the more concentrated solutions of ephedrine hydrochloride, invariably follows a rather extended period of stimulation, a period in which tonus, rate and amplitude of contracticm, either singly or collectively, may be increased.

Uretero-ureteral Anastomosis.

The accidental division or crushing of ureters during difficult gynecological operations has occurred occasionally, even with the most experienced surgeons. Suture of the divided ureter when the level of division has been too high to allow implantation in the bladder has resulted in a low percentage of permanently functioning ureters. This failure has resulted most often from progressive cicatricial stenosis due to leakage of urine. In this study the method used by McArthur for the plastic repair of a traumaticaly ruptured ureter is applied to end to end suture of the ureter in dogs and in one woman. Through a slit in the side of the proximal portion of the ureter a catheter is inserted distally toward the bladder and over it the ureteral ends are joined by 2 fine catgut sutures. Through the same slit in the ureter a snugly fitting rubber catheter is inserted toward the kidney to divert the urine from the site of suture for 8 days or more until healing occurs. The free ends of both catheters are brought outside the body in the lumbar region. The ureters of 6 dogs examined at intervals of 19 to 270 days after such an operation healed without narrowing or appreciable dilation of the lumens, with a minimum scar, without changes in the renal pelves, and without evidence of any considerable damage to the kidneys. Five months after a similar operation in a woman the ureter is slightly dilated but is not constricted at any point. The renal pelvis and calyces are not appreciably altered.

On the normal peristaltic movements of the ureter

Our present knowledge of the peristalsis of the ureter is based essentially upon the observations of Engelmann described by him about 35 years ago. He studied the peristaltic movements by simple inspection of the ureter in dogs, cats and rabbits. According to Engelmann, the contractions of the ureter in rabbits occur at intervals of 10 to 20 seconds. There were practically no other studies of the subject until a few years ago when Fagge investigated the effect of stimulation of the hypogastric nerves upon the ureter and obtained graphic records of the peristaltic movements. He makes the surprising statement that the ureter in many cases was found to be motionless or to present slight contractions or groups of contractions recurring every 30 to 60 seconds. For the last two years I have been engaged in experimental studies of the ureter, which were carried out in the laboratory of biological chemistry at the College of Physicians and Surgeons. Some of the results of that work I had the honor to present at a meeting of this Society in April, 1905. During the past summer I have studied the course of the normal peristalsis of the ureter (of the dog) at the Rockefeller Institute, under the direction of Dr. S. J. Meltzer. In dogs narcotized with morphin the peristaltic contractions of the middle part of the ureter occur at intervals varying between 6 and I 5 seconds. The curves representing these contractions are of variable but generally of fairly good size. The duration of such a contraction may vary from 5 to 15 seconds. The variations of the size and duration of these peristaltic contractions depend upon the size of the animal, the amount of secretion of urine, and many other conditions which I shall not attempt to discuss here.