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1265 Articles

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Articles published on University Of Manitoba

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Manitoba Law Journal: Criminal Law Edition (Robson Crim) 2019 Volume 42(4), Special Issue

Manitoba Law Journal: Criminal Law Edition (Robson Crim) 2019 Volume 42(4), Special Issue

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  • Journal IconSSRN Electronic Journal
  • Publication Date IconOct 7, 2019
  • Author Icon Richard Jochelson + 17
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Canola Breeding for HUMAN HEALTH

Canola Breeding for HUMAN HEALTH

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  • Journal IconCSA News
  • Publication Date IconOct 1, 2019
  • Author Icon Kaine Korzekwa
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Scientific Overview on CSCI-CITAC Annual General Meeting and 2018 Young Investigators’ Forum

The 2018 Annual General Meeting (AGM) and Young Investigators’ Forum (YIF) of the Canadian Society of Clinician Investigators (CSCI) and Clinician Investigator Trainee Association of Canada/Association des Cliniciens-Chercheurs en Formation du Canada (CITAC/ACCFC) was held in Toronto, Ontario on November 19–20, 2018, in conjunction with the University of
 Toronto Clinician Investigator Program Research Day. The theme for the meeting was “Prepare for Success—Things to Master Now for Clinician Scientists in Training”; with lectures and workshops that were designed to provide knowledge and hands-on skills to navigate life as a clinician investigator. The opening remarks were by Jason Berman (President of CSCI), Josh Abraham (President of CITAC/ACCFC) and Nicola Jones (University of Toronto Clinician Investigator Symposium Chair). The keynote speakers were Dr. Ruth Ann Marrie (University of Manitoba), who received the Distinguished Scientist Award, Dr. Davinder Jassal (University of Manitoba), who received the CSCI-RCPSC Henry Friesen Award, and Dr. Aleixo Muise (University of Toronto), who received the Joe Doupe Young Investigator Award. Dr. Minna Woo (University of Toronto), Canada Research Chair in Diabetes Signal Transduction, delivered the keynote lecture “From Onion Cells to Single Cell Seq—A Constant Change in Lenses: A perspective of an evolving clinician scientist”.
 
 The workshops, focusing on career development for clinician-scientists, were hosted by Drs. Robert Chen, Stephen Juvet, Lorraine Kalia, Phyllis Billia, Neil Goldenberg, Nicola Jones, Srdjanaa Filipovic, Jason Berman, Josh Abraham, Melanie Szweras, Joseph Ferenbok and Uri Tabori. The AGM also included presentations from clinician investigator trainees from across the country, and these abstracts are summarized in this review. Over 80 abstracts were showcased at this year’s meeting during the poster session, with six outstanding abstracts selected for oral presentations during the President’s Forum.

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  • Journal IconClinical and Investigative Medicine
  • Publication Date IconSep 29, 2019
  • Author Icon Valera Castanov + 11
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Dr. Dwight Parkinson: a Canadian neurosurgical pioneer.

In 1950, Dwight Parkinson was the first qualified neurosurgeon to arrive in Winnipeg, Manitoba. He played a monumental role in developing one of the earliest neurosurgical training programs in Western Canada. Parkinson was a pioneering neurosurgeon who served as the first president of the Canadian Neurosurgical Society in 1965. He was the epitome of the skull base neurosurgeon, which was not recognized as a distinct discipline at that time. He contributed to its development through detailed neuroanatomical study of the lateral sellar compartment (housing the parasellar venous plexus, a term he emphasized as more accurate than "cavernous sinus"). Parkinson also made seminal contributions to the management of cerebrovascular disease and offered new insights on cerebral concussion. Parkinson's dedication to clinical excellence and education laid a cornerstone for the development of neurosurgery and the neurosciences in Manitoba, making him a key figure in Canadian neurosurgery. Using published materials, online resources, hospital archives, and personal interviews, the authors conducted a systematic review of Parkinson's formative years, his development of the Section of Neurosurgery at the University of Manitoba, his achievements, and his legacy. This updated biography captures the exploits of this remarkable, and at times strictly disciplinarian, neurosurgeon-anatomist.

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  • Journal IconJournal of neurosurgery
  • Publication Date IconSep 27, 2019
  • Author Icon Andrew Ajisebutu + 4
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Associations of non-breeding shearwater species on the northeastern Newfoundland coast

MEPS Marine Ecology Progress Series Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout the JournalEditorsTheme Sections MEPS 627:1-12 (2019) - DOI: https://doi.org/10.3354/meps13112 FEATURE ARTICLE Associations of non-breeding shearwater species on the northeastern Newfoundland coast Paloma C. Carvalho*, Gail K. Davoren University of Manitoba, Winnipeg, MB R3T 2N2, Canada *Corresponding author: ccpaloma@gmail.com ABSTRACT: Prey aggregations are not uniformly distributed, driving predator species to aggregate in specific areas of high food availability. On the east coast of Newfoundland, capelin Mallotus villosus, a small forage fish, migrate inshore to spawn during the summer, providing an abundant food source for marine predators. During this period, non-breeding great shearwaters Ardenna gravis (GRSH) and sooty shearwaters A. grisea (SOSH), both long-distance migratory seabirds, aggregate in coastal Newfoundland, but it is unclear what drives their distributional patterns within this region. Using at-sea surveys, we investigated whether the density and distributional patterns of GRSH or SOSH were influenced by sea surface temperature, depth and fish (prey) density as well as the number of the other seabird species or other shearwater species (i.e. GRSH or SOSH). The presence and number of GRSH and SOSH were positively influenced by the density of the other sympatric shearwater species but were not influenced by the densities of other seabird species. These findings suggest that the benefits of foraging in close association may outweigh costs. Fish density was less important in explaining the presence and number of GRSH and SOSH than depth, as both species were mainly found together in shallow areas (<50 m) along the coast. As fish density was primarily distributed in shallow areas, reflecting predictable locations of and migratory routes to capelin spawning sites, depth (or distance from shore) and the distribution of other shearwaters may provide important cues to locate regions of high prey availability in coastal Newfoundland. KEY WORDS: Seabird distribution · Shearwater · Local enhancement · Capelin · Mallotus villosus · Predator-prey Full text in pdf format Information about this Feature Article Supplementary material NextCite this article as: Carvalho PC, Davoren GK (2019) Associations of non-breeding shearwater species on the northeastern Newfoundland coast. Mar Ecol Prog Ser 627:1-12. https://doi.org/10.3354/meps13112 Export citation Mail this link - Contents Mailing Lists - RSS Facebook - Tweet - linkedIn Cited by Published in MEPS Vol. 627. Online publication date: September 26, 2019 Print ISSN: 0171-8630; Online ISSN: 1616-1599 Copyright © 2019 Inter-Research.

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  • Journal IconMarine Ecology Progress Series
  • Publication Date IconSep 26, 2019
  • Author Icon Pc Carvalho + 1
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Effective Post-EVAR Surveillance and Management of Graft Complications Among Rural Inhabitants in Manitoba

Effective Post-EVAR Surveillance and Management of Graft Complications Among Rural Inhabitants in Manitoba

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  • Journal IconJournal of Vascular Surgery
  • Publication Date IconSep 19, 2019
  • Author Icon Matt Cwinn + 4
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Meet the First Authors.

Meet the First Authors.

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  • Journal IconCirculation Research
  • Publication Date IconSep 13, 2019
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Attitudes towards gambling in a Canadian university sample of young adults

ABSTRACTWhile studies of gambling attitudes continue to grow among national adult populations and adolescents, no study to date has explored attitudes towards gambling among young adults (adults 18–25 years of age). We address this gap by exploring gambling attitudes using the Attitudes Towards Gambling Scale (ATGS) among a sample of 1,254 Canadian young adults from the University of Manitoba (n = 399 males, 32%). Results indicate that young adults are comparable to both adolescent and mature adults with respect to attitudes towards gambling, holding slightly negative feelings towards it as an activity, but feel individuals should retain the right to gamble despite personal risk. Regression analyses show that gambling, family/peer approval of gambling, and injunctive drinking norms of family and friends are the strongest predictors of favourable attitudes towards gambling. Given the strong roles of approval of gambling and drinking in young adults’ social environments, we recommend that research needs to more robustly address the normalization of multiple problem behaviours (drug use, deviance, etc.) among family and friends. We further recommend that therapeutic interventions be geared towards establishing new norms for young adults, for which group settings addressing multiple problem behaviours are especially helpful and cost-effective.

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  • Journal IconInternational Gambling Studies
  • Publication Date IconAug 19, 2019
  • Author Icon Matthew D Sanscartier + 2
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Analysis of quantitative adult plant resistance to blackleg in Brassica napus

Leptosphaeria maculans L. causing blackleg is a highly evolved fungal pathogen that damages the rapeseed industry in Canada, Australia, and Europe. Advanced backcross populations segregating for intermediate resistance (BLMR2) and susceptible (blmr2) alleles were planted and inoculated using cotyledons. Near iso-genic lines (NILs) containing the intermediate blackleg resistance locus along with the parent lines and other controls were planted in a blackleg nursery at the University of Manitoba. ANOVA indicated a correlated significant difference between the genotypes with BLMR2 and blmr2 alleles at the seedling and adult plant stages. Heterozygous plants with both BLMR2 and blmr2 alleles showed relatively lower disease severity index (DSI) while other plants with only the blmr2 allele induced a higher DSI at seedling and adult plant stages, respectively, on a scale of 0–9. In the field, the NILs with the BLMR2 alleles consistently showed lower stem canker severity index similar to the resistant parent Surpass 400 in three consecutive years. In comparison, lines with known R genes (BLMR1 and Rlm2) showed relatively higher DSI in the field test. This demonstrated that the intermediate resistance locus performed well under severe blackleg disease pressure in the field while the NIL lines with single dominant R genes were ineffective. Because a group of isolates carrying various Avr/avr alleles was used in the field evaluation, our results suggest that the intermediate resistance locus confers horizontal resistance and has excellent potential in blackleg management in western Canadian canola production regions.

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  • Journal IconMolecular Breeding
  • Publication Date IconAug 19, 2019
  • Author Icon Hanna B Dandena + 7
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Application and sensitivity analysis of the phase change material hysteresis method in EnergyPlus: A case study

Application and sensitivity analysis of the phase change material hysteresis method in EnergyPlus: A case study

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  • Journal IconApplied Thermal Engineering
  • Publication Date IconAug 8, 2019
  • Author Icon Ali Al-Janabi + 1
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EdX participants’ profile: analysis of the factors that lead to the search for certification

Massive Online Open Courses (MOOCs) are freely accessibleonline courses with open registration. This term was first coined in 2008when professors of University of Manitoba (Canada) started an onlinecourse free and open to anyone. In 2012, two platforms were launched, EdXand Coursera. Until now, these two platforms remain as the most popularMOOCs providers in the world attracting universities from all of thecontinents. The present study performs data analysis of Harvard and MITcourses available in EdX during the first four years of operation. Theobjective was to understand students’ and courses’ profiles and the factorsthat make certifications more attractive to the participants. This paper couldidentify some factors that contribute to students' motivation in obtainingformal certification. It was important to see that variables related toengagement impact in the inclination to obtain a certification. Furthermore,demographical characteristics as sex and age are relevant so that institutionscan focus on specific targets.

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  • Journal IconRENOTE
  • Publication Date IconJul 28, 2019
  • Author Icon Rodrigo Lins Rodrigues
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Sex Work and Sexual Behaviour: Associations with Vaginal Microbiome and Cytokine Profiles in Young Women from Mombasa, Kenya

Sex Work and Sexual Behaviour: Associations with Vaginal Microbiome and Cytokine Profiles in Young Women from Mombasa, Kenya

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  • Journal IconSSRN Electronic Journal
  • Publication Date IconJun 13, 2019
  • Author Icon Aida Sivro + 14
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What Canada Can Teach Us About Addressing Childhood Poverty.

In 2017, 18% of children in the United States were living below the federal poverty level.1 Studies have documented the myriad negative impacts poverty has on child outcomes, with many lasting into adulthood. Because of its impact on early brain development, poverty in early childhood is particularly toxic, leading to lack of school readiness, poor educational outcomes, poor health, and intergenerational poverty.2 A number of questions have been raised about these impacts. Is it income poverty itself or associated covariates, such as low parental education, poor prenatal care, and parental mental health and substance use, that cause these outcomes? How important is growing up in a poor neighborhood versus growing up in a poor family? How early and how long does the child have to experience poverty for the negative effects to be seen? In this month’s issue of Pediatrics , Roos et al3 from the University of Manitoba have taken advantage of the linkable de-identified data available in Canada to answer some of these important questions. This includes census data and … Address correspondence to Benard P. Dreyer, MD, Department of Pediatrics, New York University School of Medicine, 462 1st Ave, NBV 8E-11, New York, NY 10016. E-mail: bpd1{at}nyulangone.org

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  • Journal IconPediatrics
  • Publication Date IconJun 1, 2019
  • Author Icon Benard P Dreyer
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Electrochemistry of Antibiotic Hybrids: Towards the Detection and Quantification of Antibiotic Resistance

The overuse of antibiotics in human and veterinary medicine as well as in agriculture has caused antibiotic resistance to become a global problem and national and international health organizations have called for the urgent development of new treatment strategies. The increase of antibiotic resistance in Gram-negative bacteria in particular is a major cause for concern, as many Gram-negatives cause serious infections, such as pneumonia, and only few effective antibiotics have been developed due to bacterial innate defense mechanisms, including low outer membrane permeability and high number of efflux pumps. The presented study demonstrates the thorough electrochemical characterization of antibiotic hybrid drugs, currently under development at the University of Manitoba, Canada. The interaction of these antibiotic hybrids with selected biomolecules is investigated to further our understanding about in vivo processes of drug absorption, distribution, metabolism, and excretion. Furthermore, the interaction of bacteria with the newly developed investigational antibacterial therapeutics is studied towards the quantification of antibiotic resistance in pathogens to address the dire need for innovative strategies that are able to quantify efflux and influx of agents into bacterial cells for the assessment of potential new and reliable antimicrobial candidates.

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  • Journal IconElectrochemical Society Meeting Abstracts
  • Publication Date IconMay 1, 2019
  • Author Icon Sabine Kuss + 3
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SAT-183 Activating Transcription Factor 4 (ATF4) As A Possible Mediator Of Gluconeogenic And Lipogenic Actions Of Fat Mass And Obesity Associated (FTO) In Liver

Hepatic metabolism is critical for the maintenance of whole body glucose and lipid metabolism. Excessive hepatic glucose production and de novo lipogenesis contributes to fasting hyperglycemia in diabetes and hepatic steatosis, respectively. Common genetic variants of the fat mass and obesity associated (FTO) gene are strongly associated with obesity and type 2 diabetes. However, the role of FTO in the regulation of hepatic metabolism is not well understood. We have demonstrated that increased FTO level leads to an increase in gluconeogenic glucose-6-phosphatase (G6Pase) mRNA expression in hepatic cells. Conversely, reduced FTO level or inhibition of FTO activity caused a reduction of G6Pase mRNA expression. The transcription factor activating transcription factor 4 (ATF4) is a positive regulator of the expression of gluconeogenic and lipogenic genes in hepatocytes. These findings led to the hypothesis that increased hepatic FTO expression or activity leads to an increase expression of not only gluconeogenic genes but also lipogenic genes by activating ATF4, while reduced hepatic FTO expression or activity produces opposite effects. To address this hypothesis, we examined the effect of altered FTO expression on ATF4 and lipogenic stearoyl-CoA desaturase (SCD1) mRNA levels in alpha mouse liver 12 (AML12) immortalized hepatic cell line. We also treated AML12 cells with a small molecule FTO inhibitor rhein and measured the expression level of these genes. FTO overexpression resulted in increased ATF4 and SCD1 mRNA levels. FTO knockdown resulted in a reduction of SCD1 mRNA levels. Similarly, rhein treatment (1 μM) for 24 h reduced levels of ATF4 and SCD1 mRNA without causing cytotoxicity. These data support the hypothesis that FTO acts to shift hepatic metabolism toward anabolism, leading to increased gluconeogenesis and de novo lipogenesis and ATF4 is a possible mediator of this action. Our data also suggest that reduced activity of hepatic signaling pathways involving FTO and ATF4 may be effective in reversing hyperglycemic and hepatic steatosis partly by reducing gluconeogenesis and de novo lipogenesis in the liver. Sources of Research Support: Supported by University Research Grants Program (URGP) from University of Manitoba.

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  • Journal IconJournal of the Endocrine Society
  • Publication Date IconApr 15, 2019
  • Author Icon Tooru Mizuno + 1
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Sowing on Good Soil: Canadian Scholarship on the Ukrainian Church(es)

This essay surveys material published between 1950 and 2016 by Canadian scholars who studied Ukrainian church history and theology. Particular attention is paid to works produced by members of the Eastern-rite Redemptorist and Basilian religious orders and by scholars at St. Andrew’s College and the University of Manitoba in Winnipeg, the University of Toronto and the University of St. Michael’s College in Toronto, the Canadian Institute of Ukrainian Studies at the University of Alberta, and the Metropolitan Andrey Sheptytsky Institute of Eastern Christian Studies in Ottawa.

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  • Journal IconEast/West: Journal of Ukrainian Studies
  • Publication Date IconApr 2, 2019
  • Author Icon Jaroslav Z Skira + 1
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Editorial introductions

Current Opinion in Endocrinology and Diabetes was launched in 1994, with Obesity added to the title in 2007. It is one of a successful series of review journals whose unique format is designed to provide a systematic and critical assessment of the literature as presented in the many primary journals. The fields of endocrinology and diabetes are divided into 12 sections that are reviewed once a year. Each section is assigned a Section Editor, a leading authority in the area, who identifies the most important topics at that time. Here we are pleased to introduce one of the Journal's Section Editors for this issue. SECTION EDITORS David M. HarlanDavid M. HarlanDr David M. Harlan is a graduate of the University of Michigan (Bachelor of Science) and the Duke University School of Medicine, USA. He completed his internal medicine internship and residency at the Duke University Medical Center. This was before serving for four years as a staff internist at the Navy Hospital, San Diego, CA, USA. He then returned to Duke for his fellowship training in diabetes, endocrinology, and metabolism. In 1991 he established his laboratory at the Navy Medical Research Institute, USA, where he rose to become the Director of Combat Casualty Care. He was then appointed to the faculty of the Uniformed Services University of the Health Sciences. In 1999, he moved his laboratory to the National Institutes of Health, where he became the Diabetes Branch Chief within the National Institute of Diabetes, Digestive, and Kidney Diseases. In 2010, he moved to the University of Massachusetts School of Medicine, USA, where he is the William and Doris Krupp Professor of Medicine and Diabetes Division Chief. Dr Harlan also co-directs the UMass Diabetes Center of Excellence. His research interests all relate to diabetes and include the immunopathogenesis underlying type 1 diabetes and improved care delivery models for the disease. Dan StrejaDan StrejaDr Dan Streja is Clinical Professor of Medicine at David Geffen School of Medicine at UCLA, Department of Medicine Section of Endocrinology, USA. Dr Streja received his MD from the Carol Davilla School of Medicine in Bucharest, Romania. He trained in internal medicine in Canada and subsequently undertook a fellowship in endocrinology sponsored by the Ontario Heart Foundation for studies in lipid metabolism. He taught medicine and physiology at the University of Manitoba, Canada, where he served as the Director of the diabetes clinic. He moved to the United States in 1979 and taught at UCLA since. He is a member of the American Heart Association and of the American Diabetes Association, and he is a fellow of the Royal College of Physicians of Canada and of the American Association of Clinical Endocrinologists. His main scientific interest has been in clinical research, particularly in cardiovascular prevention for patients with diabetes. He has conducted over 150 randomized trials in the field of diabetes and lipids. Dr Streja has authored chapters in five textbooks and co-authored numerous scientific publications. He has lectured in the area of lipids and cardiovascular prevention nationally, in the US, and internationally.

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  • Journal IconCurrent Opinion in Endocrinology, Diabetes &amp; Obesity
  • Publication Date IconApr 1, 2019
  • Author Icon David M Harlan + 1
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Oil behavior in sea ice: Changes in chemical composition and resultant effect on sea ice dielectrics

Oil behavior in sea ice: Changes in chemical composition and resultant effect on sea ice dielectrics

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  • Journal IconMarine Pollution Bulletin
  • Publication Date IconMar 28, 2019
  • Author Icon Durell S Desmond + 6
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Change in young people's spine pain following chiropractic care at a publicly funded healthcare facility in Canada

Change in young people's spine pain following chiropractic care at a publicly funded healthcare facility in Canada

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  • Journal IconComplementary Therapies in Clinical Practice
  • Publication Date IconMar 16, 2019
  • Author Icon Christian Manansala + 4
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Charting a future for Canada’s first Age-Friendly University (AFU)

ABSTRACT Situated within a Canadian context, but with implications for a broad range of institutional settings, this paper describes the events that preceded the adoption of the Age-Friendly University (AFU) framework at the University of Manitoba (U of M), as well as the specific strategies being employed within the university to assess and encourage age-friendliness. These include: a) the university’s Centre on Aging and its mandate to foster interdisciplinary age-related research and community dialogue, b) the creation of an interdisciplinary AFU committee and several working groups, c) innovative research projects that have assessed university age-friendliness from a variety of stakeholder perspectives, and d) an interactive undergraduate course activity being used to educate students about AFU features. Present and future AFU challenge areas and potential solutions are discussed.

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  • Journal IconGerontology & Geriatrics Education
  • Publication Date IconFeb 14, 2019
  • Author Icon Stephanie Chesser + 1
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