Articles published on Universal Screening
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- New
- Research Article
- 10.1037/spq0000723
- May 1, 2026
- School psychology (Washington, D.C.)
- Jared T Izumi + 1 more
Universal screening for social-emotional and behavioral health risk is a key part of a comprehensive multitiered system of support. This study was conducted to examine the incremental predictive validity of the Social, Academic, and Emotional Behavior Risk Screener (SAEBRS) on spring academic outcomes and to examine the disproportionate identification of students using SAEBRS. To answer these questions, we used data from a single elementary school and conducted mixed-effects models to account for students nested in teachers. SAEBRS risk status did not significantly predict spring reading scores; however, being at risk on the SAEBRS predicted lower spring math scores (B = -0.210) after controlling for fall math scores, attendance, grade level, and special education status. When examining race/ethnicity, biological sex, and special education status on SAEBRS risk status, only special education status significantly predicted risk on the SAEBRS (B = 1.004; odds ratio = 2.728). Limitations, future research, and implications are explained. (PsycInfo Database Record (c) 2026 APA, all rights reserved).
- New
- Research Article
1
- 10.1245/s10434-025-18778-5
- May 1, 2026
- Annals of surgical oncology
- Nuria Valdés + 12 more
Malnutrition is associated with poor surgical outcomes, but evidence supporting targeted nutritional intervention within multimodal pathways remains limited. We assessed whether preoperative nutritional support, delivered selectively to malnourished colorectal cancer patients within an Enhanced Recovery After Surgery (ERAS) framework, was associated with postoperative outcomes comparable to those of well-nourished patients. We conducted a prospective observational cohort study in an ERAS-certified Spanish hospital between January 2020 and December 2021. A total of 187 consecutive adult patients undergoing elective primary colorectal cancer resection were screened for malnutrition by using Malnutrition Universal Screening Tool and Global Leadership Initiative on Malnutrition criteria. Malnourished patients received individualized nutritional counseling and oral nutritional supplements ≥ 7 days preoperatively, per ESPEN guidelines. Primary outcomes were length of stay (LOS) and 30-day postoperative complications. Multivariable logistic and Cox regression models adjusted for age, sex, body mass index, American Society of Anesthesiologists class, and nutritional status. The cohort's mean age was 69.3 ± 9.6 years, 62.6% were male, and 42 (22.4%) were diagnosed with malnutrition. No significant differences were observed in complication rates (38.1% vs. 31.7%, P = 0.276) or LOS (median 8 vs. 7 days, P = 0.36) between malnourished and well-nourished groups. In multivariable analysis, malnutrition was not independently associated with postoperative complications (adjusted odds ratio 1.47; 95% confidence interval 0.7-3.07; P = 0.31) or prolonged LOS (adjusted odds ratio 0.77; 95% confidence interval 0.53-1.12; P = 0.17). No 30-day deaths occurred. Within a structured ERAS program, targeted preoperative nutritional support was associated with postoperative outcomes that were not worse than those of well-nourished peers. These findings support a selective "screen-and-treat" nutritional strategy in routine perioperative care.
- New
- Research Article
- 10.4330/wjc.v18.i4.115942
- Apr 26, 2026
- World Journal of Cardiology
- Taner Bayram Celebi + 3 more
BACKGROUND Sudden cardiac death in adolescent athletes, although rare, carries substantial public health impact. Screening methods remain debated internationally. Cost effectiveness, diagnostic yield and logistical ability remain as points of contention. AIM To evaluate the diagnostic yield, accuracy, and cost-effectiveness of electrocardiogram (ECG)-based screening programs for adolescent athletes. The secondary aim is to discuss ethical and psychological issues that may arise from universal screening methods. METHODS A systematic review of literature from 1998-2025 was conducted, assessing ECG-inclusive screening, transthoracic echocardiography follow-up, and comparative international models. An additional segment was created to analyze more qualitative aspects of the screening method including psychological concerns, and physician comfortability. RESULTS ECG screening demonstrated superior sensitivity compared to history and physical exam alone. International programs varied in diagnostic yield, false-positive rates, and feasibility. A majority of physicians support ECG screening for athletes if proper training and financial feasibility were possible. CONCLUSION ECG-inclusive screening improves detection of high-risk cardiac conditions but requires careful consideration of cost, resource availability, and implementation strategies. A targeted approach to specific high-risk populations would benefit most from targeted screening and may serve as a pilot framework for future universal screening.
- New
- Research Article
- 10.1177/13872877261443699
- Apr 25, 2026
- Journal of Alzheimer's disease : JAD
- Yu Fujiwara + 5 more
BackgroundWith the advent of anti-amyloid-β monoclonal antibody therapies and the growing societal burden of dementia, early identification of Alzheimer's disease and related dementias has become a clinical priority.ObjectiveTo evaluate the diagnostic accuracy of a machine learning model using a neuropsychological battery to classify individuals as Healthy controls, mild cognitive impairment (MCI), or Dementia, and to identify neuropsychological tests and cognitive domains that contributed most to classification accuracy, determining optimal tests for dementia screening.MethodsIn this retrospective cross-sectional single-center study, we analyzed 590 participants evaluated for suspected dementia. The final sample comprised 74 Healthy controls, 190 individuals with MCI, and 326 with Dementia (including 269 with Alzheimer's disease). Scores from the Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment Japanese version (MoCA-J), Rivermead Behavioural Memory Test (RBMT), Japanese Adult Reading Test (JART), and Wechsler Adult Intelligence Scale-III were input into a random forest machine learning model. Model performance was assessed using the area under the ROC curve (AUC). A variable importance analysis determined each test's relative contribution to classification.ResultsThe multiclass model achieved an AUC of 0.898. RBMT was the strongest contributor, exceeding MMSE and MoCA-J. In borderline MMSE/MoCA-J subsets, adding RBMT improved classification performance for both Healthy versus MCI and MCI versus Dementia decisions.ConclusionsRBMT provides substantial incremental value for dementia-related diagnostic discrimination, particularly as a second-line assessment when brief screening results are borderline. However, its administration time may limit its role as a universal first-line screening tool.
- New
- Research Article
- 10.1002/adaw.34893
- Apr 24, 2026
- Alcoholism & Drug Abuse Weekly
- Alison Knopf
Rates of teen use of cannabis increased following legalization, and continued to increase after retail sales became legal (including for teens), but then decreased after the COVID‐19 pandemic, researchers have found. This suggests that societal disruptions as well as changes in cannabis policy affect adolescent cannabis use. The researchers concluded that universal screening should exist for teen cannabis use.
- New
- Research Article
- 10.1186/s12879-026-13422-3
- Apr 24, 2026
- BMC infectious diseases
- Meng Hsuan Kuo + 8 more
Despite guideline-mandated universal screening, adherence to hepatitis B virus (HBV) testing before the initiation of biological or targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs) remains suboptimal, placing patients at risk for HBV reactivation (HBVr). We retrospectively studied 1,909 adults starting b/tsDMARD therapy from 2004 to 2024, comparing three stages: baseline (2004-2016), education (2017-2020), and work-flow-integrated (2021-2024). In the last stage, a workflow-embedded clinical decision support system (CDSS) was integrated into computerized order entry to automatically verify HBV serologic status and generate missing screening orders at the point of prescription. The outcomes assessed were pre-treatment HBV screening completion, monitoring frequency, and HBVr-related clinical events. HBV screening rates progressively improved across stages. HBsAg testing increased from 91% at baseline to 98% during the workflow integrated stage. Completion of the two-marker panel (HBsAg/anti-HBc) increased from 63% to 93%, whereas full three-marker panel testing increased from 47% to 90%. These process improvements were accompanied by a significant reduction in HBVr, which decreased from 5.2% to 1.5% (p < 0.001), and hepatitis flares, which decreased from 1.9% to 0.2% (p < 0.001). However, antiviral prophylaxis before b/tsDMARD initiation remains uncommon (4.2%) and HBV DNA monitoring is infrequently performed. Workflow-embedded CDSS led to almost universal HBV screening and notable reductions in HBV reactivation and flares. The remaining risk suggests that future systems should include automated long-term monitoring and better enforcement of prophylactic guidelines.
- New
- Research Article
- 10.1111/jmwh.70124
- Apr 24, 2026
- Journal of midwifery & women's health
- Daisy Goodman + 4 more
Hepatitis C virus (HCV) affects an estimated 50 million people worldwide. Prevalence among persons who are pregnant has increased 161% between 2009 and 2017, largely driven by increasing maternal injection drug use. Although the American College of Obstetricians and Gynecologists and the Centers for Disease Control and Prevention now recommend universal prenatal HCV screening, diagnosis during pregnancy too often does not result in timely treatment postpartum. Consistent with research at other institutions, internal review at our medical center revealed that referrals to gastroenterology or infectious disease specialists resulted in low follow-through, with few patients receiving curative therapy. To address this gap, we implemented a patient-centered program integrating HCV care into the outpatient prenatal and postpartum service at our rural academic medical center. This article describes a practice innovation which streamlines the process from confirmatory testing during pregnancy to the initiation and follow-up for direct-acting antiviral treatment postpartum. Embedding postpartum HCV treatment within routine perinatal services reduces barriers to cure and is well within the scope of midwifery and other obstetric practice. Adoption of this patient-centered approach accelerates progress toward regional and global HCV elimination goals.
- New
- Research Article
- 10.1002/pd.70153
- Apr 21, 2026
- Prenatal diagnosis
- Alyssa Yeung + 5 more
We conducted a retrospective cohort study of singleton pregnancies with anti-SSA and/or anti-SSB antibodies who underwent serial fetal echocardiography between 2010 and 2022. Surveillance was weekly from 18 to 28weeks' gestation and monthly thereafter, with mechanical PR intervals obtained by pulsed Doppler. Prolonged PR interval was defined as ≥ 140ms on three consecutive measurements. A total of 124 pregnancies met the inclusion criteria. Screening began at a median of 19.5week gestation and continued until 34weeks, with a median of 14 ultrasounds and 10 PR interval measurements per pregnancy. Three fetuses (2.4%) were diagnosed with heart block: two with first-degree block and one with complete CHB, corresponding to one affected fetus per 359 screening ultrasounds. After dexamethasone, first-degree block either normalized or remained stable. Complete CHB did not reverse. In a high risk, predominantly Hispanic and non-Hispanic black population, universal serial PR-interval screening detected conduction abnormalities at expected rates, but only two of three cases were identified early enough for potential intervention and detection required substantial screening burden per case. These findings support the reconsideration of universal screening and suggest that risk-targeted surveillance may better balance detection with screening burden.
- New
- Research Article
- 10.1210/endrev/bnag010
- Apr 21, 2026
- Endocrine reviews
- Michelle Toth Castillo + 5 more
Gestational diabetes mellitus (GDM), defined as glucose intolerance that starts during pregnancy, represents a major public health challenge because it is a major cause of adverse maternal and fetal outcomes and presents a significant high risk of diabetes, obesity, and cardiovascular disease for both mother and infant. The diagnosis of GDM is currently made through oral glucose tolerance tests (OGTT); other markers of glycemic control have notably failed for GDM diagnosis: Since the treatment of GDM reduces the incidence of adverse pregnancy outcomes, screening for GDM with OGTTs in pregnancy weeks 24-28 is the standard of care in most nations worldwide. However, universal screening is difficult to achieve due in part to the fact that OGTTs are cumbersome and uncomfortable. Thus, the importance of detecting glucose intolerance in pregnant women, the possibility of reducing with treatment the associated risks, the low sensitivity of glycemic markers in pregnancy, and the multiple problems associated with OGTTs highlight the significance of exploring alternative screening/diagnostic methods that are sensitive, accurate, and well tolerated by patients. In this review, we summarize our discovery, development, and clinical validation in six human studies of plasma glycated CD59 (pGCD59), the glucose modified form of the key complement inhibitor CD59, as a biomarker for screening, diagnosis, and monitoring of GDM.
- New
- Research Article
- 10.3928/23258160-20260302-01
- Apr 21, 2026
- Ophthalmic surgery, lasers & imaging retina
- Pauline Scherm + 9 more
This brief report describes the incidence and characteristics of ocular abnormalities in healthy term newborn infants (HTNI) in 5,000 consecutive eye examinations from a database of 32,000 infants from 17 hospitals in São Paulo, Brazil. Imaging consisted of five views of the retina (optic nerve center, superior, inferior, nasal, temporal) with 130° wide-angle lens and one view of the anterior segment in each eye. These images were curated on four separate occasions for the presence or absence of ocular abnormality by a pediatric retina specialist. All images were obtained within 72 hours of birth. A total of 59,792 images were curated: Right Eye Normal (21,473 images), Left Eye Normal (21,983 images), Right Eye Abnormal (8,397 images), Left Eye Abnormal (7,939 images). An ocular abnormality appeared in 37.7% of patients; 4.88% showed a referral-warranted pathology. Based on these data, it is not unreasonable to consider instituting universal newborn eye screening in HTNI.
- New
- Research Article
- 10.3390/encyclopedia6040093
- Apr 21, 2026
- Encyclopedia
- Rebecca S Rouland + 1 more
Perinatal mood disorders (PMDs) affect approximately 15% of birthing persons during the pregnancy or postpartum (up to one year after birth) time period. People who recently gave birth and are of diverse backgrounds and identities, especially those who are oppressed, are disproportionately affected by PMDs and may experience these conditions differently. One such group is low-income birthing persons living in urban areas. This article will summarize PMDs, including their prevalence rates and how they are disproportionately experienced among low-income birthing persons living in urban areas. The factors to be reviewed include racism, cultural stigma, community stressors, issues with access to services, lack of resources, socioeconomic concerns, and healthcare system problems. Additionally, how PMDs among low-income birthing persons living in urban areas can be prevented, identified, and treated will be discussed. Strategies include practicing cultural humility and promoting anti-oppressive practice, building positive relationships with birthing persons, utilizing formal and informal social supports, promoting community engagement, sharing resources and tangible supports, following universal screening recommendations, addressing barriers to care, and advocating for effective policies.
- New
- Research Article
- 10.51407/mjpch.v32i1.442
- Apr 20, 2026
- Malaysian Journal of Paediatrics and Child Health
- Erwin Khoo Jiayuan + 8 more
Background: In late 2025, the United States Centers for Disease Control and Prevention shifted from a universal hepatitis B birth dose recommendation to a risk-based framework. This statement reaffirms the critical importance of maintaining Malaysia’s universal 24-hour birth dose policy within its National Immunisation Programme. Main Text: Malaysia’s universal birth dose, introduced in 1989, has been a monumental public health success, reducing childhood HBV surface antigen prevalence to ~0.3%. Abandoning this policy would jeopardise decades of progress. The universal approach acts as an essential “vaccine safety net”, protecting against systemic failures in antenatal screening, documentation, and care coordination that a risk-based strategy cannot overcome. Immunologically, the birth dose is crucial due to the neonatal vulnerability to chronic infection. The policy is also highly cost-effective and grounded in principles of equity and justice, ensuring protection for all newborns regardless of socioeconomic or geographic factors. Strengthening complementary measures, such as universal antenatal screening and digital health records, is encouraged. Conclusions: The Malaysian Paediatric Association, the Academy of Medicine of Malaysia College of Paediatrics, and the Malaysian Society of Paediatric Gastroenterology, Hepatology and Nutrition unanimously urge Malaysia to maintain its universal HBV birth dose. This policy remains a fundamental, non-negotiable pillar of child health and hepatitis B elimination efforts in the national context.
- Research Article
- 10.12968/bjon.2026.0112
- Apr 16, 2026
- British journal of nursing (Mark Allen Publishing)
- Wendy Milligan + 1 more
Disease-related malnutrition in adults is a costly problem. It is associated with increased morbidity and mortality but can go unrecognised and therefore untreated. The Malnutrition Universal Screening Tool (MUST), launched in 2003, is a validated screening tool to support the early recognition of malnutrition risk in adults across a wide variety of health and care settings. It remains one of the most widely used screening tools for adults in the UK. This review sets out the current evidence to support its use and discusses common challenges with completing it in practice. Practical information and signposting to the latest supporting resources are provided.
- Research Article
- 10.3390/pediatric18020059
- Apr 15, 2026
- Pediatric reports
- Rogaya Alshugair + 11 more
Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is among the most common inherited enzymatic disorders worldwide and is an important risk factor for neonatal hyperbilirubinemia. Regional data from Western Saudi Arabia based on universal newborn screening remain limited. Objectives: To determine the prevalence of G6PD deficiency among newborns delivered at a tertiary center in Jeddah, Saudi Arabia, and to evaluate its association with clinically relevant outcomes, including early-onset jaundice (<24 h), need for phototherapy, admission for hyperbilirubinemia management, and readmission after discharge. Methods: We conducted a retrospective cohort study at King Abdulaziz Medical City, Western Region, Jeddah, Saudi Arabia, between January 2020 and May 2025. Cord blood samples from live-born infants were screened using a qualitative fluorescent spot test. Demographic variables (sex, gestational age, birth weight) and jaundice-related outcomes were extracted from the electronic medical record. Categorical variables were compared using chi-square testing, with p < 0.05 considered statistically significant. Results: Among 14,964 screened newborns, 489 were identified as G6PD deficient, yielding a prevalence of 3.3%. Prevalence was higher in males than in females (5.6% vs. 0.9%). Among the G6PD-deficient infants, early-onset jaundice occurred in 17.2%, phototherapy was required in 36.0%, and 16.5% were admitted for hyperbilirubinemia management. Readmission for worsening jaundice requiring phototherapy occurred in 11.0%, and no exchange transfusions were required. Compared with term infants, late preterm infants had higher rates of early-onset jaundice (11/49, 22.4% vs. 73/440, 16.6%) and phototherapy use (22/49, 45.0% vs. 154/440, 35.0%) (p < 0.01). Conclusions: G6PD deficiency was identified in a substantial proportion of newborns in this large screened cohort and was associated with clinically significant jaundice-related outcomes, particularly among late preterm infants. These findings underscore the importance of universal screening and structured postnatal follow-up to reduce the risk of severe hyperbilirubinemia and its complications. Early identification of G6PD-deficient infants should be accompanied by careful bilirubin monitoring, clear discharge planning, and timely post-discharge follow-up, especially for those born late preterm.
- Research Article
- 10.1542/peds.2025-071208
- Apr 14, 2026
- Pediatrics
- Alexandra Huttle + 4 more
This study describes general and subspecialty pediatricians' standardized suicide risk screening practices, variation in screening across subspecialties, and whether knowledge of the American Academy of Pediatrics (AAP) recommendations is associated with standardized suicide risk screening. We analyzed survey data from the 2023 American Board of Pediatrics Maintenance of Certification program. Survey items assessed use of standardized suicide risk screening tools, specific tools employed, adoption of universal screening approaches, and knowledge of AAP recommendations. Adjusted logistic regression examined associations between clinician characteristics and screening practices, and between knowledge of recommendations and screening. Overall, 49.1% (5195) of eligible pediatricians responded, with 5003 included in the analysis. Standardized suicide risk screening was reported by 36.7% (1836), with emergency medicine physicians significantly more likely to report using standardized tools than general pediatricians (adjusted odds ratio [AOR] = 2.83; 95% CI: 2.13-3.77). Compared with pediatricians who reported that they were not at all knowledgeable of AAP recommendations, those who reported that they were moderately or very knowledgeable were significantly more likely to report standardized suicide risk screening (AOR = 1.53, 95% CI: 1.29-1.83). Among pediatricians who reported screening, 73.1% (1249) used a universal screening approach for children aged 12years and older, with significant variation across subspecialties in the tools used. Approximately 1 in 3 pediatricians reported using standardized suicide risk screening, with significant variability across subspecialties. Knowledge of AAP recommendations was associated with screening, suggesting that widespread dissemination of practice guidelines may increase implementation, particularly in subspecialty practices where early identification and timely interventions are less common.
- Research Article
- 10.70267/emsgh.2602.0112
- Apr 13, 2026
- Explore Medical Science and Global Health
- Haiyu Mao
The preschool years, spanning from 3 to 6 years of age, represent a pivotal and irreversible critical period for the maturation of human visual function. During this window, the ocular structures and neural pathways underlying vision undergo rapid development and plastic changes, making the visual system highly susceptible to the influence of environmental and physiological factors. Anisometropia, a prevalent refractive disorder characterized by an asymmetric refractive state between the two eyes, has emerged as a major threat to the normal visual development of preschool children. If left undiagnosed and without timely intervention, this condition can trigger a cascade of visual impairments, including amblyopia, binocular vision dysfunction, stereoscopic vision loss, and even long-term reading difficulties and learning disabilities, which can profoundly impact a child’s academic performance, motor skills, and overall quality of life in adulthood. This paper systematically elaborates on the definition, clinical classification, and epidemiological characteristics of anisometropia in preschool children, and further explores the current status and application value of various early screening methods, including population-based screening tools and clinical diagnostic gold standards. It also formulates targeted and hierarchical intervention strategies based on the severity of anisometropia, encompassing optical correction, amblyopia training, and long-term follow-up management. Additionally, this study conducts an in-depth analysis of the far-reaching clinical and social significance of standardized early screening and scientific intervention for this condition. The research findings confirm that universal and standardized early refractive screening can significantly improve the early detection rate of anisometropia in preschool children, and individualized intervention measures, such as timely full optical correction combined with personalized visual training, can effectively improve the visual acuity of the affected eye, restore binocular vision balance, and drastically reduce the incidence of irreversible amblyopia and abnormal visual development. Based on these conclusions, this paper proposes that refractive screening for anisometropia should be incorporated into the routine health examination system for preschool children in China, a standardized multi-disciplinary management system involving families, kindergartens, and medical institutions should be established, and precise and individualized intervention measures should be implemented to build a comprehensive defense line for the visual health of preschool children and lay a solid foundation for their healthy growth and future development.
- Research Article
- 10.12669/pjms.42.4.12475
- Apr 11, 2026
- Pakistan Journal of Medical Sciences
- Özge Tuncer + 2 more
Objectives: Older adults receiving home healthcare are at increased risk of falls due to environmental, nutritional, psychological, and functional vulnerabilities. Fear of falling (FoF) may further restrict activity and contribute to adverse outcomes. This study aimed to examine factors associated with fall history and FoF using multivariate logistic regression analysis. Methodology: A cross-sectional study was conducted among 320 older adults (≥65 years) receiving home healthcare at Izmir Bozyaka Training and Research Hospital between November 2023 and January 2024. Data were collected during home visits using validated tools: FRAIL Scale, Malnutrition Universal Screening Tool (MUST), Barthel Index, Itaki Fall Risk Scale, Six-Item Screener, Tinetti Balance and Gait Test, and Geriatric Depression Scale-Short Form (GDS-SF). Fall history and FoF were self-reported. Predictors were identified using multivariate logistic regression models. Results: The mean age was 81.52±7.57 years; 53.8% were female. Fall history and FoF were reported by 58.8% and 54.4%, respectively. Multivariate logistic regression analysis revealed that fall history was significantly predicted by environmental hazards (OR=37.37), age ≥80 (OR=2.60), high risk on Itaki (OR=12.15) and Tinetti (OR=5.44) scales, malnutrition risk (OR=4.64), and moderate/severe depression (OR=2.58). FoF was significantly associated with obesity (OR=5.84), calf circumference ≤31 cm (OR=3.55), environmental hazards (OR=8.90), malnutrition risk (OR=3.33), and moderate/severe depression (OR=3.66). Conclusion: Falls and fear of falling in home-dwelling older adults are multifactorial issues predominantly driven by environmental safety and functional mobility. Comprehensive geriatric assessments, focusing on home environment modifications and nutritional support, are essential to reduce fall-related morbidity in this population.
- Research Article
- 10.1097/md.0000000000048272
- Apr 10, 2026
- Medicine
- Oguzhan Pekince + 1 more
Developmental dysplasia of the hip (DDH) is a preventable condition when detected early through ultrasound screening. Although universal and free DDH screening is available in Turkey, adherence to screening programs may differ between population groups. This study aimed to investigate factors associated with missed opportunities for DDH ultrasound screening among Turkish and refugee infants. This single-center, hospital-based retrospective cohort study was conducted between August 10, 2020, and September 30, 2022. The main cohort included 9020 infants (5466 Turkish and 3554 refugee). A nested sub-cohort was formed comprising infants who had not undergone DDH screening at our institution. Parents of infants in the sub-cohort (120 Turkish and 80 refugee infants) were interviewed via structured telephone calls to determine reasons for missed screening. Univariate and multivariate generalized linear models were used to identify factors associated with missed screening opportunities. The rate of missed DDH screening was 15.8% among Turkish infants and 40.0% among refugee infants. The most common reason for nonattendance was lack of awareness of the screening program, reported by 47.4% of Turkish and 84.4% of refugee parents. In univariate analyses, maternal nationality, parental education level, birth order, and delayed or skipped vaccination were associated with missed screening. In the multivariate model, refugee status remained the only independent predictor of missed screening (adjusted relative risk: 2.41; P = .010). Despite unrestricted and free access to healthcare services in Turkey, refugee infants were more than twice as likely to miss DDH screening compared with Turkish infants. Missed screening was primarily driven by lack of awareness rather than structural barriers. Targeted educational interventions and culturally tailored strategies are needed to improve screening adherence among refugee populations.
- Research Article
- 10.3390/jcm15072757
- Apr 6, 2026
- Journal of clinical medicine
- Husam Abu Sini + 7 more
Background: Hepatitis B virus (HBV) reactivation in oncology patients receiving chemotherapy can cause severe hepatitis, including hepatic failure and death. Universal HBV screening before chemotherapy initiation can reduce HBV-related morbidity; however, screening practices vary widely, and guideline recommendations continue to evolve. Objective: The aim of this study was to evaluate the implementation of universal HBV screening in oncology patients and its effectiveness in identifying active infection, prior exposure, and individuals at risk for HBV reactivation. Methods: We implemented universal HBV screening at Rambam Health Care Campus in January 2018 for all patients initiating chemotherapy. This retrospective cohort study analyzed 1614 oncology patients who underwent chemotherapy between January 2018 and April 2024. Screening included testing for HBsAg, anti-HBc, and anti-HBs serology. HBV DNA testing was performed in patients with positive HBsAg and/or anti-HBc serology. Patients with known HBsAg positivity or those already receiving antiviral therapy were excluded. Results: Of the screened patients, 16 (1.0%) were HBsAg-positive, and 134 (8.3%) were HBsAg-negative/anti-HBc-positive. Detectable HBV DNA was identified in four patients (3%) within the latter group. One additional patient was classified as high risk for HBV reactivation based on the planned chemotherapy regimen. Overall, 21 patients met criteria for prophylactic antiviral therapy; however, prophylaxis was administered to only 17 patients. Notably, when applying the 2015 ASCO guidelines, only a single patient within the subgroup of HBsAg-negative, anti-HBc-positive, and HBV DNA-negative patients would have qualified for HBV serologic screening based on chemotherapy-related risk alone. Conclusions: Universal HBV screening prior to chemotherapy enables the identification of patients with active or prior HBV infection who would not have been detected using risk-based screening strategies alone. Our findings further support the implementation of universal HBV screening in oncology settings to prevent HBV reactivation and its potentially severe consequences.
- Research Article
- 10.1177/00048674261434407
- Apr 5, 2026
- Australian & New Zealand Journal of Psychiatry
- Tracey Mackle + 7 more
Background: Universal screening for perinatal mental illness is recommended in Australia; however, these tools do not screen for perinatal post-traumatic stress disorder (PTSD). While existing perinatal PTSD tools show validity, they vary in diagnostic agreement, and most are focused on PTSD following childbirth. Early detection of PTSD symptoms at any phase of perinatal care is critical to improve maternal/infant outcomes and engagement with effective treatment. Unfortunately, gaps remain in practice for identifying perinatal PTSD. Aim: The aim of the study was to develop a screening tool to detect current symptoms of perinatal PTSD or higher risk of developing the disorder, resulting from index perinatal event(s) or experience(s) during conception, pregnancy and the postpartum. Methods: If any perinatal trauma was endorsed, participants completed an online questionnaire and if consenting, a semi-structured clinical telephone interview during their current pregnancy. Findings: Twenty-five items were submitted for exploratory factor analysis, n = 114, and the results supported a two-factor solution. After removing items with poor loadings, a 17-item, two-factor solution explained 68.36% of the total variance. Each of the components had excellent internal consistency; component one α = .954 and component two α = .897. Following a receiver operating characteristic analysis n = 52, the optimal cutoff score of ⩾11 was identified with 90.9% sensitivity and 61% specificity. Conclusion: Moderate predictive validity of the tool shows promise for detecting those currently experiencing symptoms of perinatal PTSD and at higher risk of developing the disorder, supporting utility in clinical settings, pending future validation.