Twenty-nine overweight men and women (body mass >25) participated in this six week outpatient study. The participants were randomized to either a 1500 calorie 40/30/30 diet [40%CHO] (n=14) or a 1500 calorie Step 1 diet [60% CHO] (n=15). The 40/30/30 diet consisted of 40% CHO, 30% protein, 30% fat, the Step I Diet consisted of 60% CHO, 15% protein, and 25% fat. All subjects participated in Universal Circuit Training™, one hour, three times per week supervised by an exercise physiologist. All subjects met two to four times (avg.=3) over six weeks with a registered dietitian for review and analysis of compliance to the study diets. Both groups lost a significant amount of weight (p<0.05) after 6 weeks of treatment (40% CHO, -2.8 kg; 60% CHO, -1.2 kg). However, the 40% CHO group lost more weight and a greater amount of body fat (-2.6 kg; p<0.05), while the 60% CHO (-1.0 kg) group did not achieve significant fat loss. There were no significant changes for both groups in serum glucose, HgBA 1C, total cholesterol, high density lipoprotein, low density lipoprotein, or triglycerides during the study. Profile of Mood States (POMS) for fatigue and vigor was also analyzed in both study groups with the following results: 44% reduction in fatigue (p<0.05) for the 40% CHO group with a corresponding 15.7% increase in vigor (non-significant;p>0.05). The changes within the 60% CHO group did not achieve significance in either fatigue or vigor. In conclusion, the 1500 calorie 40/30/30 diet resulted in a significantly greater fat and weight loss compared with the 1500 calorie Step 1 diet over six weeks.
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