Uniform Type Research Articles

Isotonic subgroup selection

Abstract Given a sample of covariate–response pairs, we consider the subgroup selection problem of identifying a subset of the covariate domain where the regression function exceeds a predetermined threshold. We introduce a computationally feasible approach for subgroup selection in the context of multivariate isotonic regression based on martingale tests and multiple testing procedures for logically structured hypotheses. Our proposed procedure satisfies a non-asymptotic, uniform Type I error rate guarantee with power that attains the minimax optimal rate up to poly-logarithmic factors. Extensions cover classification, isotonic quantile regression, and heterogeneous treatment effect settings. Numerical studies on both simulated and real data confirm the practical effectiveness of our proposal, which is implemented in the R package ISS.

Attention as the dimension that deteriorates first in patients with cognitive impairment after myocardial infarction

Abstract Background Previous publications by our team indicated a high prevalence (approximately 35%) of cognitive impairment (CI) in patients after myocardial infarction (MI). Moreover, we observed that the presence of peri-infarction deficits was not always associated with their occurrence after 6 months of follow-up and vice versa. This was the basis for distinguishing 4 groups of patients: a) group 1 – CI present peri-infarction and after 6 months; b) group 2 – CI present only peri-infarction; c) group 3 – CI present only after 6 months; d) group 4 – no CI during the study. Purpose The aim of the current study is to analyse the type of CI in patients after MI with a focus on its changes within the 4 groups mentioned. Methods The study included 326 patients hospitalised for MI treated by percutaneous coronary intervention. Cognitive function was assessed twice using the Mini–Mental State Examination (MMSE) and the Clock Drawing Test (CDT)-Shulman version during the first hospitalisation (on day 2-3 after MI) and 6 months later. In addition, the occurrence of sleep, aggression and mood disorders was assessed. The constructed research model was analysed with artificial intelligence algorithms. Results Persistent CI (group1) was found in 8.9%, peri-infarct CI (group 2) in 16.3%, and only after 6 months (group 3) in 7.7% of study participants (as assessed by MMSE). Analysis of the cognitive domains showed that in those who improve (group 2) or worsen cognitive function (group 3), analogous changes in attention function occurred, respectively improving in 81% and worsening in 100% of subjects in a given group. It was observed that there is a group of patients with a CI on the MMSE who perform CDT correctly, 12% peri-infarct and 11% at 6-month follow-up, respectively. Patients with a normal CDT score but CIs found in the MMSE have impaired attentional function regardless of the time of assessment. Conclusion CIs can occur both immediately after MI and during subsequent follow-up. However, after 6 months of intensive anti-atherosclerotic treatment (post-MI), cognitive functions improve in some patients, and deteriorate in others. At the same time, the cognitive function that undergoes similar changes in these groups is attention. The uniform type of impaired cognitive function and the lack of specific differences between the 4 groups allow us to assume a uniform etiology of cognitive deficits. Patients with normal CDT and disorders present in MMSE show deficits in attention functions. Performing CDT and using the MMSE component assessing attention function could prove sufficient for the initial assessment of cognitive functions in the population of patients after MI. The results require confirmation in a larger patient population.

Evaluation of the Effect of Surgical Drapes on Intraoperative Hypothermia: A Randomized Clinical Trial.

Many patients experience unintended hypothermia in intraoperative processes. This randomized clinical trial aims to investigate the impact of surgical drapes on hypothermia during the intraoperative period. A randomized clinical trial was conducted from April 2019 to November 2020 in the Department of Anesthesiology and Reanimation/Operating Rooms at an education and research hospital. Out of 205 patients assessed for eligibility, 74 underwent elective abdominal surgery and were randomized into two groups: nonwoven surgical drapes and woven surgical drapes. The study had two stages: preoperative and intraoperative. Preoperative data were collected using information and evaluation forms, while intraoperative assessment involved forms for wetness and weight. Tympanic and esophageal temperatures were recorded every 15 minutes, and surgical drapes were weighed with a precision scale before and after surgery. There was no significant difference between the two groups in terms of body mass index, irrigation amount, surgery duration, gender, and preoperative shivering (p > 0.05). A statistically significant difference was found in preoperative body temperature (36°C), type of surgery, and intraoperative hypothermia (p < 0.05). Both types of surgical drapes were wet, but this difference was not statistically significant between the nonwoven group (mean ± SD [1368 ± 607]) and the woven group (mean ± SD [1335 ± 636], p = 0.824). This study demonstrated that neither woven nor nonwoven surgical drapes, nor the wetness of the surgical drapes, had a significant effect on intraoperative hypothermia. However, there is a need for randomized controlled trials involving uniform types of surgery related to the topic.

Prediction of Lithium Deposition By Electrochemical Noise Method in Li-Ion Batteries

Electrochemical noise measurement methods have established a significant presence in corrosion literatures and through these measurements, it becomes feasible to discern the corrosion mode and make a clear distinction between localized and uniform corrosion types, particularly when examined alongside post-mortem studies.In recent years, the increase in the use of lithium-ion batteries demands that the tests to be performed on the batteries are faster, easier, cheaper and, if possible, non-destructive and non-perturbing. While some electrochemical noise studies on batteries have commenced, the existing literature on this subject is limited and questionable. Electrochemical noise measurement, in Lithium based batteries has the potential to serve as a non-invasive diagnostic tool for assessing battery health. One of our previous studies has demonstrated an increased voltage noise in non-rechargeable batteries with Li/MnO2 chemistry upon exposure to a short circuit, indicating detectable morphological changes in metallic lithium due to non-homogenous depletion of lithium anode through electrochemical noise measurement.In Lithium-Ion batteries, lithium deposition refers to the undesired formation of metallic lithium, commonly in the form of dendrites, on the battery’s anode during charge and discharge cycles. This phenomenon is a consequence of uneven lithium-ion plating and stripping, leading to localized overplating. This growth of lithium dendrites poses significant risk, including internal short circuits, compromised battery integrity, and the potential for thermal runaway. These issues can result in reduced battery performance, safety concerns, and shortened cycle life. Effectively addressing lithium deposition is essential for enhancing the safety and reliability of lithium-ion batteries in various applications.Similarly to our previous publication, the electrochemical noise method shows promise as a non-invasive approach to investigate the understand deposition of metallic lithium by monitoring the voltage noise during charge and discharge cycling of batteries. For this purpose, NMC/Graphite pouch and coin cells are employed. In this presentation, we will delve into the details of electrochemical noise in lithium-based batteries, discussing the method’s reliability in assessing lithium deposition in NMC/Graphite lithium-ion batteries and presenting preliminary results. Figure 1

Evolutionary patterns and functional effects of 3D chromatin structures in butterflies with extensive genome rearrangements

Chromosome rearrangements may distort 3D chromatin architectures and thus change gene regulation, yet how 3D chromatin structures evolve in insects is largely unknown. Here, we obtain chromosome-level genomes for four butterfly species, Graphium cloanthus, Graphium sarpedon, Graphium eurypylus with 2n = 30, 40, and 60, respectively, and Papilio bianor with 2n = 60. Together with large-scale Hi-C data, we find that inter-chromosome rearrangements very rarely disrupted the pre-existing 3D chromatin structure of ancestral chromosomes. However, some intra-chromosome rearrangements changed 3D chromatin structures compared to the ancestral configuration. We find that new TADs and subTADs have emerged across the rearrangement sites where their adjacent compartments exhibit uniform types. Two intra-chromosome rearrangements altered Rel and lft regulation, potentially contributing to wing patterning differentiation and host plant choice. Notably, butterflies exhibited chromatin loops between Hox gene cluster ANT-C and BX-C, unlike Drosophila. Our CRISPR-Cas9 experiments in butterflies confirm that knocking out the CTCF binding site of the loops in BX-C affected the phenotypes regulated by Antp in ANT-C, resulting in legless larva. Our results reveal evolutionary patterns of insect 3D chromatin structures and provide evidence that 3D chromatin structure changes can play important roles in the evolution of traits.

Monitoring the Vertical Variations in Chlorophyll-a Concentration in Lake Chaohu Using the Geostationary Ocean Color Imager

Due to the external environment and the buoyancy of cyanobacteria, the inhomogeneous vertical distribution of phytoplankton in eutrophic lakes affects remote sensing reflectance (Rrs) and the inversion of surface chlorophyll-a concentration (Chla). In this study, vertical profiles of Chla(z) (where z is the water depth) and field Rrs (Rrs_F) were collected and utilized to retrieve the vertical profiles of Chla in Lake Chaohu in China. Chla(z) was categorized into vertically uniform (Type 1: N = 166) and vertically non-uniform (Type 2: N = 58) types. Based on the validation of the atmospheric correction performance of the Geostationary Ocean Color Imager (GOCI), a Chla(z) inversion model was developed for Lake Chaohu from 2011 to 2020 using GOCI Rrs data (Rrs_G). (1) Five functions of non-uniform Chla(z) were compared, and the best result was found for Chla(z) = a × exp(b × z) + c (R2 = 0.98, RMSE = 38.15 μg/L). (2) A decision tree of Chla(z) was established with the alternative floating algae index (AFAIRrs), the fluorescence line height (FLH), and wind speed (WIN), where the overall accuracy was 89% and the Kappa coefficient was 0.79. The Chla(z) inversion model for Type 1 was established using the empirical relationship between Chla (z = surface) and AFAIRrs (R2 = 0.58, RMSE = 10.17 μg/L). For Type 2, multivariate regression models were established to estimate the structural parameters of Chla(z) combined with Rrs_G and environmental parameters (R2 = 0.75, RMSE = 72.80 μg/L). (3) There are obvious spatial variations in Chla(z), especially from the water surface to a depth of 0.1 m; the largest diurnal variations were observed at 12:16 and 13:16 local time. The Chla(z) inversion method can determine Chla in different layers of each pixel, which is important for the scientific assessment of phytoplankton biomass and lake carbon and can provide vertical information for the short-term prediction of algal blooms (and the generation of corresponding warnings) in lake management.

The Use of Multidimensional Item Response Theory Estimations in Controlling Differential Item Functioning

ABSTRACT Differential Item Functioning (DIF), which indicates differences in item performance between individuals of equivalent ability in different groups, is the focus of this study. The aim was to investigate the effectiveness of Multidimensional Item Response Theory (MIRT) ability estimation in controlling DIF under different simulation conditions. For the purpose of the study, different experimental conditions were created by varying the number of dimensions, DIF percentage, DIF size and DIF type. Depending on the changed conditions, Item Response Theory and MIRT estimations were performed; the significance of the differences in Type I error and power ratios obtained from the DIF analysis of the data sets obtained from the estimations were tested with Factorial ANOVA. This study shows that in tests with DIF, taking into account the ability level related to the structure by estimating with MIRT provides a correction in the ability estimation and controls the DIF effect. In the Uniform DIF type, Type 1 error increases as the DIF size and percentage increase, and multidimensional estimation provides more correction on power ratios as the DIF size and number of dimensions increase. Whereas in the non-uniform DIF type, Type 1 error increases as DIF size increases; multidimensional estimation provides more correction on power ratios as DIF size, DIF percentage and number of dimensions increase. In this context, it is recommended that practitioners should perform MIRT estimation in the presence of DIF and conduct DIF investigations based on the corrected ability estimation taking into account the ability scores related to the structure.

Resident demand-oriented selection and spatial layout strategy for public sports facilities

In response to elevated living standards and evolving recreational values, public sports facilities have become a focal point. This study, targeting the central districts of Yiyang City across 17 neighborhoods, integrates questionnaire surveys, in-depth interviews, and geographic information system analysis to address the diversified needs in sports infrastructure. It reveals a discrepancy characterised by uniform facility types and flawed layouts, notably in Heshan and Ziyang, that fail to satisfy the diversified demands of residents. Consequently, the research introduces a bottom-up strategy, emphasising the need for facility selections and spatial layouts informed by community needs. Furthermore, it highlights the importance of demographic factors such as age, income, and education in guiding facility placement strategies to accommodate a broad spectrum of users. By doing so, the study contributes a novel, resident-focused framework to the discourse on public sports facilities, promoting sustainable and inclusive urban sports environment development.

Studies on the Pollen Morphology of Simaroubaceae

In continuation to a previous communication on the pollen morphology of Asiatic representatives of the family Simaroubaceae (Basak, 1963), pollen grains of 17 more taxa have been described and illustrated. The study reveals that the pollen grains are more or less of uniform type. The significance of these pollen characters in taxonomic considerations is discussed.

Lymphatic Uptake of a Highly Lipophilic Protease Inhibitor Prodrug from a Lipid-Based Formulation is Limited by Instability in the Intestine

Dabigatran etexilate (DABE) is a lipophilic double alkyl ester prodrug of dabigatran (DAB) which is a serine protease inhibitor used clinically as an anticoagulant. Recently, translocation of serine protease enzymes, including trypsin, from the gut into the mesenteric lymph and then blood has been associated with organ failure in acute and critical illnesses (ACIs). Delivery of DABE into mesenteric lymph may thus be an effective strategy to prevent organ failure in ACIs. Most drugs access the mesenteric lymph in low quantities following oral administration, as they are rapidly transported away from the intestine via the blood. Here, we examine the potential to deliver DABE into the mesenteric lymph by promoting association with lymph lipid transport pathways via co-administration with a lipid-based formulation (LBF). A series of self-emulsifying LBFs were designed and tested in vitro for their potential to form stable DABE loaded emulsions and keep DABE solubilised and stable over time in simulated gastrointestinal conditions. The LBFs were found to form fine emulsions with a droplet size of 214 ± 30 nm and DABE was stable in the formulation. The stability of DABE in vitro in simulated intestinal conditions, plasma and lymph samples was also evaluated to ensure stability in collected samples and to evaluate whether the prodrug is likely to release active DAB. Ultimately, a highly uniform and stable self-emulsifying Type III A LBF of DABE was chosen for progression into in vivo studies in male Sprague Dawley rats to confirm the lymphatic uptake and plasma pharmacokinetics. Both in vitro and in vivo in plasma and lymph, DABE was rapidly converted to an intermediate and DAB. The main species present in vivo in both plasma and lymph was DAB and mass transport of DABE and DAB in lymph was minimal (∼0.5 % of dose). Importantly, the concentration of DABE in lymph was substantially (20–176 fold) higher than in plasma, supporting that if the prodrug were stable and did not convert to DAB in the intestine, it would be lymphatically transported. Future studies will therefore focus on optimizing the design of the prodrug and formulation to improve stability during absorption and further promote lymphatic uptake.

Analysis of the properties of bast raw materials as a component of fabric for military uniforms

The relevance of the present research is determined by the need to replace imported raw materials for manufacturing military clothing with Ukrainian raw materials of industrial hemp and oilseed flax. The aim was to analyse the quality properties of bast raw materials and determine their potential for use in military uniforms. In the course of solving the set goals, the methods of complex analysis, synthesis, observation, measurement, comparison and generalisation of the obtained results and information were applied, as well as standard methods generally accepted in the light industry were implemented. It is noted that hemp cottonin and oilseed flax fiber, in contrast to other natural fibers, are more durable, resistant to abrasion, decay, and are characterised by sanitary, antistatic, hypoallergenic and antibacterial properties. It has been revealed that fabrics made of these fibers are durable, have high resistance to ultraviolet radiation, hold colour well, do not fade, etc. The academic paper analyses scientific studies on the use of this raw material for various types of military clothing, protective body armour, and gunpowder production. By determining the main properties of the bast raw materials under study, the possibility of using this raw material in some types of military uniforms was established. The main feature of the structure and components of the research was the systematic and comprehensive study of the quality properties of bast raw materials at all stages of its processing. It was proposed to use oilseed flax fibers and hemp cottonin instead of cotton fibers in fabrics for military purposes. This will reduce the state’s material expenditures on the purchase of fabric for the defense sector and, at the same time, it will help bring the Ukrainian light industry to a new quality level and increase the competitiveness of Ukrainian manufactured goods in the global market. Knowledge of the properties of bast raw materials can help manufacturers improve the quality of fabrics for military purposes

Abstract 4232: Exploring chemotherapy resistance in pancreatic cancer: Insights from a 3D organoid model

Abstract Pancreatic cancer is marked by a dismal prognosis, with a 5-year survival rate at approximately 10%. A key contributor to its lethality is the development of chemotherapy resistance, followed by early metastasis. However, studies elucidating the mechanisms behind chemotherapy resistance in pancreatic cancer are limited. Previous research has relied on 2D cell line models, which present limitations, such as uniform cell types that fail to capture tumor heterogeneity and an inaccurate representation of clinical realities, wherein resistance often develops gradually rather than through continuous exposure to high drug concentrations. In this study, we developed a more sophisticated organoid model of chemotherapy resistance. Six organoids from three patients were matched to study chemotherapy resistance in a personalized context. Comprehensive whole-exome sequencing and transcriptomic analyses were performed, along with an examination of chemotherapy resistance protein expression and EMT-related markers. Notably, differential expression levels of CK19 and Vimentin were observed between samples. Our analysis also focused on the expression of the ATP-Binding Cassette Subfamily G Member 2 (ABCG2) gene in chemoresistant organoids. Western blot analysis indicated a significant increase in ABCG2 expression in these organoids compared to controls. According to the Moffitt RNA signature, the primary and corresponding chemoresistant organoids retained their molecular subtype classifications both before and after developing chemoresistance. Gene set enrichment analysis uncovered significant upregulation of pathways related to DNA repair and cell cycle regulation, particularly the G2M checkpoint, in chemoresistant organoids. Furthermore, gene ontology functional analysis suggested a notable overrepresentation of activities related to amino acid transmembrane transport and extracellular matrix constituents, underscoring their potential role in the chemoresistance phenotype. Citation Format: Hee Seung Lee. Exploring chemotherapy resistance in pancreatic cancer: Insights from a 3D organoid model [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 4232.

Magnetic Field Enhancements in the Solar Wind: Diverse Processes Manifesting a Uniform Observation Type?

AbstractWithin the solar wind throughout the inner heliosphere, observations reveal the presence of magnetic field enhancements accompanied by thin current sheets at varying distances from the sun and across different longitudes and latitudes. Two primary explanations have been proposed to elucidate these phenomena: Solar wind‐dust interaction and interlacing flux ropes. In this study, we employ multi‐fluid Magnetohydrodynamics (MHD) and Hall MHD models to simulate these hypotheses, respectively. Our findings indicate a concurrence between both models and the observed phenomena, suggesting that both processes may result in the same kind of enhancement. Furthermore, both models make predictions pointing to additional types of observational data, occurring at distinct spatial or temporal stages of the interaction. This convergence of model predictions with empirical data underscores the need for further observational and modeling studies to comprehensively test these models. This research enhances our knowledge of the inner heliosphere's dynamics and the influence of the solar wind on the Earth's magnetosphere, thereby shedding light on critical aspects of space weather and its potential impact on our planet.

Hydrogeochemical and Isotopic Characterisation of the Učja Aquifer, NW Slovenia

The groundwater characteristics of the Učja aquifer were investigated using geochemical and isotopic data. The water discharge and physico-chemical properties of the groundwater and the Učja River reflect the climate that is characteristic of the area. The mixed snow/rainfall regime is characteristic for the Učja Valley, with the highest discharges appearing during the spring snowmelt and autumn precipitation, and the lowest discharges in the winter and especially summer months. The temperature of the groundwater and the Učja River is lower in winter and higher in summer. The specific electrical conductivity values indicate a very permeable carbonate aquifer. Higher conductivity values were observed in spring and autumn at all sampling sites, which is related to snowy and rainy periods. The groundwater from the Učja aquifer indicates a uniform type of water (Ca-Mg-HCO3), with Ca2+, Mg2+ and HCO3– the most abundant ions. Differences in Ca2+ and Mg2+ concentrations and in the Mg2+/Ca2+ molar ratio between sampling sites were observed. Those springs with lower Mg2+ and lower Mg2+/Ca2+ molar ratios indicate limestone recharge areas, and those springs with higher Mg2+ and molar ratios indicate interaction with the dolomite hinterland. The pH values confirm alkaline waters characteristic of carbonate aquifers. The hydrogen (δ2H) and oxygen (δ18O) isotope values suggest the main source of water is from precipitation from a complex mixing of maritime and continental air masses. An altitude isotopic effect is observed with minor δ18O and δ2H depletion at higher altitude sampling sites compared to those springs at lower altitudes. The altitude isotopic effect is most prominent in spring. The δ13CDIC values indicate the dissolution of carbonates and the degradation of organic matter.

Differential Gene Expression Patterns in Peach Roots under Non-Uniform Soil Conditions in Response to Organic Matter.

Organic matter (OM) amendments are often encouraged in sustainable agriculture programs but can create heterogeneous soil environments when applied to perennial crops such as peaches (Prunus persica (L.) Batsch). To better understand the responses of peach roots to non-uniform soil conditions, transcriptomic analysis was performed in a split-root study using uniform soil (the same soil type for all roots) or non-uniform soil (different soil types for each half of the root system) from either (1) autoclaved sand (S), (2) autoclaved sand with autoclaved compost (A), or (3) autoclaved sand with compost which included inherent biological soil life (B). Each uniform soil type (S, A, and B) was grouped and compared by uniform and non-uniform soil comparisons for a total of nine treatments. Comparisons revealed peach roots had differentially expressed genes (DEGs) and gene ontology terms between soil groups, with the S and B groups having a range of 106-411 DEGs and the A group having a range of 19-94 DEGs. Additionally, six modules were identified and correlated (p > 0.69) for six of the nine treatment combinations. This study broadly highlights the complexity of how OM and biological life in the rhizosphere interact with immediate and distant roots and sheds light on how non-homogenous soil conditions can influence peach root gene expression.

Engineering a dual-loop molecular circuit with buffering capability to solve molecular information tasks.

Molecular circuits, as an effective strategy for implementing artificial biochemical networks, have been widely constructed to process molecular-level information tasks both in vivo and in vitro. However, the complex and diverse structures of molecular devices, along with inflexible signal output methods, pose significant challenges for molecular circuits to handle complex molecular information tasks. In response to the growing field of molecular circuits, we design an exonuclease-driven fan-out molecular device (FMD) with a programmable cascade approach capable of receiving uniform signal types and transmitting multifunctional signals. Combined with the buffering reaction proposed here, the approach expands the dynamic properties of biochemical networks. Unlike the conventional delay strategy, the buffering process not only withstands transient changes in transmission signals, but also delays the transmission of lossless signals. Furthermore, we construct a dual-loop molecular circuit with adjustable buffering modes, thereby enabling signal amplification, time delay, and a differentiated output. Finally, we develop a method to obtain the colorimetric output of dual pulse signals driven by a dual-loop molecular circuit with buffering and hence precisely classify multiple signals. This work promises programmable and multifunctional molecular circuits in nanomachines, molecular computing, and biomedical applications.

Капитализм и социализм в изменившемся мире: парадокс конвергенции

The current dramatic confrontation between East and West can be seen as a continuation in a converted form of the struggle between two opposing social systems, capitalist and socialist, in the twentieth century. The article deals with the problem of convergence of capitalist and socialist elements, paradoxically received external impulses as a result of the rivalry between the two world systems, as well as under the influence of globalization. Modern society, being a complex system, cannot develop successfully, by locking itself into some single, uniform type of organization. It needs the combination of market institutions, focused primarily on private interests, with planning, focused on the public interest. Planning is not yet socialism, but its necessary however insufficient condition. Another necessary condition is a policy that limits the moral flaws of capitalism, and facilitates the spiritual and moral improvement of society.

Analysis of noise behavior and reliability of pocket doped negative capacitance FET under the impact of trap charges and temperature

This paper represents an in-depth investigation of low to high frequency noise performance of highly doped double pocket double gate NCFET (HDDP-DG-NCFET) and single gate NCFET (SG-NCFET) in the existence of Uniform and Gaussian trap charges at various frequencies and temperatures (200 K–400 K). The drain current noise spectral density (Sid) and Gate voltage noise spectral density (Svg) at different frequencies in existence of both type of trap charges are explored. In addition, the Sid as a function of frequency for various ferroelectric thicknesses (Tfe) is examined in the existence of Uniform trap charges. The findings show that, at lower frequencies flicker noise dominates, while at higher frequencies, the dominant noise element is diffusion noise. For the whole range of considered frequencies, the Generation-Recombination (G-R) noise is more substantial in existence of trap charges. It has been found that, the net Sid value of the HDDP-DG-NCFET for Uniform and Gaussian types of trap distribution is 6.98 × 10−14A2/Hz and 6.17 × 10−14A2/Hz, respectively. Moreover, the examination of Sid for various Tfe in presence of traps illustrates the significance of the ferroelectric layer in obtaining lower value of net Sid, particularly in the higher frequency region and the minimal net Sid value for Tfe = 7 nm as compared to other Tfe values. Finally, to examine the device's reliability, the temperature investigation for the noise in the non-existence and existence of trap charges demonstrates that, the impact of an increase in noise caused by the existence of trap charges is much pronounced at lower temperatures and smaller gate voltages, where G-R noise is observed to be the dominant noise component.

Numerical Simulations on Combustion and Heat Transfer in Porous Medium with Different Gyroid Triply Periodic Minimal Surfaces Structures

ABSTRACT To investigate the influence of the porous medium with Triply Periodic Minimal Surfaces (TPMS) structures on lower concentration methane combustion. This study analyzed the flow field and heat transfer in the porous medium with three types, i.e. an axial gradual period type, a conical type and a uniform type, through the pore-scale simulation (PSS) approach. In cases of this study, the flashback equivalence ratio of the conical PMB is about 12.5% lower than that of the gradient PMB at the same inlet flow velocity, and the blow-off inlet flow velocity of the conical PMB is about 30% higher than that of the gradient PMB at the same equivalence ratio. Moreover, the flame shape is closely related to the local solid structure and flow velocity. The solid surfaces radiation heat transfer occurred mainly in regions with high solid temperature gradients. Additionally, the absolute value of the radiant heat flux is about 1/4 to 1/5 of the total heat flux, which reflects the proportion of thermal convection in the heat transfer on the solid surface. Convective heat transfer between solid and fluid occurred mainly in the areas of heat recuperation known as preheat zone, and higher inlet flow rates significantly increase the upstream convective heat transfer intensity.

Separability and classification of multipartite quantum states

We study separability in arbitrary multipartite quantum systems based on principal base matrices. Necessary conditions are presented for different kinds of separable states. These conditions can give a complete classification of multipartite quantum states. While the usual Bloch representation of a density matrix uses three types of generators, the representation with principal base matrices has one uniform type of generator which simplifies computation. In this paper, we take advantage of this simplicity to derive useful and operational criteria to detect multipartite separability. We first obtain criteria on detecting separable, separable, separable and fully separable four-partite quantum states. We then study k-separability for multipartite quantum states in arbitrary dimensions. Detailed examples are given to show that our criteria are able to detect more entanglement states than some existing criteria.