Typical Wind Research Articles

Effects of low-frequency pulsed electrical stimulation at the common peroneal nerve on chronic refractory wounds of the lower limb: A randomized controlled trial.

Electrical stimulation (ES) has been shown to substantially enhance the quality of life by alleviating pain in patients with chronic wounds. This study aimed to observe the effects of low-frequency pulsed wearable ES at the common peroneal nerve on chronic refractory wounds of the lower limb. Forty-eight participants were randomly divided into control group (n = 24) and treatment group (n = 24) in this study. The control group received standard wound care (SWC) exclusively, whereas the treatment group was administered both SWC and the wearable low-frequency ES targeting the common peroneal nerve. Measurements of wound area, pain intensity, wound status, and quality of life scores were systematically recorded both before and after 4 weeks treatment. After 4 weeks of intervention, the percentage area reductionwas significantly higher in the treatment group compared to the control group (Z = -3.9, p < 0.001), and the healing rate of the treatment group was significantly higher than that of the control group (33% vs. 4%). Moreover, the visual Analog Scale for Pain score (β = -0.65, p = 0.019), the Bates-Jensen Wound Assessment Tool score (p < 0.05), and the questionnaire on quality of life with chronic wounds (Wound-Qol) score (β = -4.23, p = 0.003) were significantly decreased in the patients in the treatment group compared to the control group. The wearable low-frequency pulsed ES at the common peroneal nerve for the treatment of chronic refractory wounds showed significant improvement and were far superior compared to SWC. Future research should broaden its scope to include a diverse range of wound types and benefit from collaboration across multiple research centers.

Analysis of the Eddy current of water heating device to convert wind energy directly into heat: Case study maldo island, South Korea

The Eddy Current of Water Heating (ECWH) system introduces a pioneering approach for converting wind energy into heat, marking a significant step in renewable energy technology. The current study focuses on refining the ECWH system by evaluating eight distinct heat generator models. Each model is selected based on its magnet configurations and pole numbers to maximize power efficiency at rotational speeds ranging from 100 to 500 rpm. This selection strategy is designed to provide a deep understanding of not only system efficiency across a spectrum of technical specifications but also the practical limitations of experimental research considerations. Energy efficiency is thoroughly analyzed for four models over a power input range of 120 to 2193 W. Wind speed data collected over a year from Maldo Island, west coast of South Korea, simulates the Weibull distribution of wind speeds and estimates total power production by employing the QBlade software. This study aims to explore the practicality of converting wind's kinetic energy directly into thermal energy through the ECWH system. Our findings indicate that the ECWH system outperforms conventional permanent magnet alternators, particularly in its ability to generate more power at lower angular velocities and wind speeds—a crucial feature for locales like Maldo Island, where typical wind speeds range from 3 to 6 m/s, considered low to moderate. With an energy efficiency exceeding 90%, generating an annual power output of 2266.3 kWh, and achieving a facility utilization rate of 10.34%, the results underscore the potential of the ECWH system as an efficient and sustainable solution for heating in areas with similar wind conditions.

Interpretable semi-supervised clustering enables universal detection and intensity assessment of diverse aviation hazardous winds

The identification of aviation hazardous winds is crucial and challenging in air traffic management for assuring flight safety, particularly during the take-off and landing phases. Existing criteria are typically tailored for special wind types, and whether there exists a universal feature that can effectively detect diverse types of hazardous winds from radar/lidar observations remains as an open question. Here we propose an interpretable semi-supervised clustering paradigm to solve this problem, where the prior knowledge and probabilistic models of winds are integrated to overcome the bottleneck of scarce labels (pilot reports). Based on this paradigm, a set of high-dimensional hazard features is constructed to effectively identify the occurrence of diverse hazardous winds and assess the intensity metrics. Verification of the paradigm across various scenarios has highlighted its high adaptability to diverse input data and good generalizability to diverse geographical and climate zones.

Research on the Power Output of Different Floating Wind Farms Considering the Wake Effect

For floating wind turbines, one of the most interesting and challenging issues is that the movement of the rotor is strongly related to its floating platform, which results in corresponding variations in the wake characteristics of the turbine. Because the aerodynamic efficiency of the downstream turbines is affected by the wake characteristics, the power output will consequently vary depending on the different types of floating wind turbines and floating wind farms used. In this study, the rotor movement, wake characteristics, and corresponding wind farm power output are analyzed using a numerical method for three typical floating wind turbines: the semisubmersible type, spar buoy type, and tension leg platform type with a 5 MW configuration. A fixed-bottom monopile wind turbine is adopted as a benchmark. The simulation results show that of the three floating wind turbines, the rotor position and wake center are most dispersed in the case of the spar buoy type, and its wake also has the lowest impact on downstream wind turbines. Additionally, the power output of the corresponding spar buoy type wind farm is also the highest at different wind speeds, followed by the semisubmersible type, tension leg platform type, and then the fixed-bottom type. In particular, at low wind speeds, the wake effects differ significantly among the various types of wind turbines.

The Differences in the Origination and Properties of the Near-Earth Solar Wind between Solar Cycles 23 and 24

The dependence of the sources and properties of the near-Earth solar wind on solar cycle activity is an important issue in solar and space physics. We use the improved “two-step” mapping procedure that takes into account the initial acceleration processes to trace the near-Earth solar winds back to their source regions from 1999–2020, covering solar cycles (SCs) 23 and 24. Then, the solar wind is categorized into coronal hole (CH), active region (AR), and quiet Sun (QS) solar wind based on the source region type. We find that the proportions of CH and AR (QS) wind during SC 23 are higher (lower) than those during SC 24. During solar maximum and declining phases, the magnetic field strength, speed, helium abundance (A He), and charge states of all three types of solar wind during SC 23 are generally higher than those during SC 24. During solar minimum, these parameters of solar wind are generally lower during SC 23 than those during SC 24. There is a significant decrease in the charge states of all three types of solar wind during the solar minimum of SC 23. The present statistical results demonstrate that the sources and properties of the solar wind are both influenced by solar cycle amplitude. The temperatures of AR, QS, and CH regions exhibit significant differences at low altitudes, whereas they are almost uniform at high altitudes.

Infected nursery stock and poor silvicultural practices contribute to development of Ceratocystis manginecans wilt and canker disease in Eucalyptus pellita

In Indonesia and Malaysia, Eucalyptus pellita has replaced large areas of Acacia mangium plantations as the latter species is highly susceptible to C. manginecans. This strategy may not be effective in the long term as E. pellita is also susceptible to Ceratocystis wilt and canker disease though it has higher tolerance than A. mangium. Furthermore, the pathogen has the capacity to evolve and adapt to new hosts. To highlight the need for careful sanitation in nurseries and the potential impact of wounding during silvicultural operations, two experiments were conducted to (i) demonstrate the ability of cryptic Ceratocystis infections in nursery plants to develop into Ceratocystis wilt and canker disease after planting out and (ii) assess the risk of Ceratocystis infection and disease development from different wound types. In the nursery, three-month-old mini-cuttings of seven E. pellita clones were artificially wounded and inoculated with two isolates of Ceratocystis manginecans near the base of the stem. The disease incidence and lesion length were measured one month later, just prior to planting out. After four months of growth in the plantation, the trees were harvested and stems sliced longitudinally to measure the length of xylem discolouration. Six of 36 ramets of susceptible clones died and the length of xylem discolouration was significantly greater in susceptible clones than in tolerant clones. The second experiment was based on inoculation of 12-month-old plantation-grown trees of one clone of E. pellita with one isolate of C. manginecans using six different wounding methods. The inoculated wounds on the trees all produced xylem discolouration, except for those that only penetrated the outer bark. Disease incidence was greater at stem heights of 30 to 90 cm than on the basal stem or branch stub. The experiment emphasised the importance of minimising the risk of C. manginecans infection following wounding in the nursery and in the field as the discolouration is an indication of xylem blockage that can lead to tree mortality.

The Asymmetrical Distribution of a Dominant Motional Electric Field within the Martian Magnetosheath

Attributed to the lack of an Earth-like global intrinsic dipole magnetic field on Mars, the induced electromagnetic field environment plays a crucial role in the evolution of its atmosphere. The dominant motional electric field (EM) induced by the bulk motion of the magnetic field within the Martian magnetosheath serves to accelerate ions toward escape velocity, thereby forming a plume escape channel. However, the distribution morphology of EM itself has received limited attention in previous research. In this study, by taking advantage of the multi-fluid Hall-MHD model cooperating with the Martian crustal field model, we focus on elucidating the physical mechanisms underlying the asymmetrical distribution of EM and examining the influence of the crustal field on this asymmetry. The results obtained from the simulation conducted in the absence of the crustal field indicate that the EM is more intense within the −ZMSE magnetosheath, where EM is directed toward Mars, primarily due to its corresponding higher velocity and a stronger magnetic field at lower solar zenith angles. The Martian crustal field has the ability to enhance the local EM around the inner boundary of the magnetosheath by amplifying both the magnetic field and its associated velocity. Accordingly, these findings provide valuable insights into the asymmetric nature of EM within the Martian magnetosheath under typical quiet-time solar wind conditions.

Electrospun nanofibrous wound dressings with enhanced efficiency through carbon quantum dots and citrate incorporation

Nanofibers show promise for wound healing by facilitating active agent delivery, moisture retention, and tissue regeneration. However, selecting suitable dressings for diverse wound types and managing varying exudate levels remains challenging. This study synthesized carbon quantum dots (CQDs) from citrate salt and thiourea using a hydrothermal method. The CQDs displayed antibacterial activity against Staphylococcus aureus and Escherichia coli. A nanoscaffold comprising gelatin, chitosan, and polycaprolactone (GCP) was synthesized and enhanced with silver nanoparticle-coated CQDs (Ag-CQDs) to form GCP-Q, while citrate addition yielded GCP-QC. Multiple analytical techniques, including electron microscopy, FT-IR spectroscopy, dynamic light scattering, UV–Vis, photoluminescence, X-ray diffraction, porosity, degradability, contact angle, and histopathology assessments characterized the CQDs and nanofibers. Integration of CQDs and citrate into the GCP nanofibers increased porosity, hydrophilicity, and degradability—properties favorable for wound healing. Hematoxylin and eosin staining showed accelerated wound closure with GCP-Q and GCP-QC compared to GCP alone. Overall, GCP-Q and GCP-QC nanofibers exhibit significant potential for skin tissue engineering applications.

Multi-Objective Sensitivity Analysis of a Wind Turbine Equipped with a Pumped Hydro Storage System Using a Reversible Hydraulic Machine

A typical wind system captures wind energy and converts it into electricity, which is then converted to DC for battery storage using an AC/DC converter; an inverter then supplies AC electricity at the grid frequency. However, this solution involves losses in electronic components and incurs costs and environmental impacts associated with battery storage. To address these issues, a different wind system layout configuration is considered, where the energy storage duties are assumed by a hydro storage system employing a reversible hydraulic pump (referred to as a Pump as Turbine). This solution utilises an elevated reservoir connected to the Pump as Turbine to compensate for fluctuations in wind and load; this approach offers lower costs, a longer lifespan, reduced maintenance, and a smaller waste management cost. This study focuses on a comprehensive sensitivity analysis of the new wind system power layout, considering multiple objectives. Specifically, the analysis targets the net change in the mass of water (potential energy) stored in the pumped hydro system, the captured wind energy, and the torque provided in hydraulic turbine mode. On the other hand, the design variables are represented by the Pump as Turbine-specific speed, the hydraulic system gearbox ratio, and the pump head. To assess how solutions are affected by random changes in wind speed and external load, the sensitivity analysis considers the multi-objective optimisation problem showing for both the wind speed and the external load a stochastic contribution.

Revealing the molecular mechanisms in wound healing and the effects of different physiological factors including diabetes, age, and stress.

Wounds are the common fates in various microbial infections and physical damages including accidents, surgery, and burns. In response, a healthy body with a potent immune system heals that particular site within optimal time by following the coagulation, inflammation, proliferation, and remodeling phenomenon. However, certain malfunctions in the body due to various diseases particularly diabetes and other physiological factors like age, stress, etc., prolong the process of wound healing through various mechanisms including the Akt, Polyol, and Hexosamine pathways. The current review thoroughly explains the wound types, normal wound healing mechanisms, and the immune system's role. Moreover, the mechanistic role of diabetes is also elaborated comprehensively.

ANTIMICROBIAL WOUND DRESSINGS FOR FULL-THICKNESS INFECTED BURN WOUNDS.

Infection of wounds delays healing, increases treatment costs, and leads to major complications. Current methods to manage such infections include antibiotic ointments and antimicrobial wound dressings, both of which have significant drawbacks, including frequent reapplication and contribution to antimicrobial resistance. In this work, we developed wound dressings fabricated with a medical-grade polyurethane coating composed of natural plant secondary metabolites, cinnamaldehyde, and alpha-terpineol. Our wound dressings are easy to change and do not adhere to the wound bed. They kill gram-positive and -negative microbes in infected wounds due to the Food and Drug Administration-approved for human consumption components. The wound dressings were fabricated by dip coating. Antimicrobial efficacy was determined by quantifying the bacteria colonies after a 24 h of immersion. Wound healing and bacterial reduction were assessed in an in vivo full-thickness porcine burn model. Our antimicrobial wound dressings showed a > 5-log reduction (99.999%) of different gram-positive and gram-negative bacteria, while maintaining absorbency. In the in vivo porcine burn model, our wound dressings were superior to bacitracin in decreasing bacterial burden during daily changes, without interfering with wound healing. Additionally, the dressings had a significantly lower adhesion to the wound bed. Our antimicrobial wound dressings reduced the burden of clinically relevant bacteria more than commercial antimicrobial wound dressings. In an in vivo infected burn wound model, our coatings performed as well or better than bacitracin. We anticipate that our wound dressings would be useful for the treatment of various types of acute and chronic wounds.

Wintertime column modeling in Jezero crater, Mars: Period of near-fog and a dust event

The diurnal water cycle was studied at a Jezero crater base site using M2020 observations and adsorptive column modeling in a cool midwinter period just before a dust peak and at the peak. During low-dust sols 566–571 the observed air relative humidity (RH) at 1.45 m height was high, 40–90% near dawn. For the typical nocturnal wind speed of 2 m/s at 1.45 m and column water of 9.7 μm, the model's diurnal air temperatures and RH were within observations. For weaker winds model-RH increased as in some of the observed sols. In a nearly calm experiment fog formed from 1.45 m upward. Ground frost appeared independently of wind, but only if adsorption was disabled. The dust peak at around sol 577 was also well simulated with the same wind and absolute humidity as before the event, but relative humidities dropped dramatically due to the dust-enhanced higher nocturnal temperatures.

A Novel Potential Treatment for Diabetic Foot Ulcers and Non-Healing Ulcers - Case Series.

<p>Introduction: Appropriate care and treatment of a wound is the need of the hour whether it is an infected or a non-infected wound. If wound healing is delayed for some reason, it leads to serious complications and further increases the hospital stay and cost of treatment. Herein, we describe a novel antimicrobial wound dressing formulation (VG111), with an objective to generate the preliminary data showing the distinct advantages in various types of wounds. <p> Method: This case series involved the treatment of acute cases of wounds or chronic wounds that did not respond well to conventional wound healing treatments with VG111 in patients with different etiologies. Thirteen cases of patients that included patients with diabetes, pressure ulcers, burns, trauma, and others treated with VG111 showed rapid wound healing in all the cases, even obviating the need for a graft when complete skin regeneration occurred. <p> Result: This was illustrated by clearing of the wound infections, reduction/disappearance of the exudate, appearance of intense granulation, epithelialization, and anti-biofilm activity followed by complete wound closure. This VG111 precludes the need for systemic antimicrobial agents in localized infections and therefore, this single agent is an attempt to address the limitations and the drawbacks of the available products. <p> Conclusion: Despite patients belonging to the old age group and having comorbidities like diabetes, still VG111 showed effective rapid wound healing, and that too without any scar formation in hardto- heal, infected, and non-infected wounds.</p>.

REGECEL (an Oxidized Regenerated Cellulose) Provides Superior Bioactivity Effect on Microorganisms.

Patients who need to be readmitted to the hospital because of complications from infections or require long-term care and rehabilitation face substantial financial hardships. To ensure the safety of patients undergoing surgery, it is crucial to implement measures that prevent wound infections before and after the procedure. Antibacterial wound dressings are essential to prevent infections during surgical procedures. There are various types of antibacterial wound dressings available on the market, such as silver-based dressings, hydrocolloid dressings, polyhexamethylene biguanide, alginate dressings, collagen-based dressings, and iodine-based dressings. We used each type (standard, knit, fibril, and non-woven) of a commercial brand of oxidized regenerated cellulose (ORC) called Regecel to test bacterial growth. The choice of antibacterial wound dressing depends on the type of wound being treated. Different bacterial strains require specific culture conditions to thrive and grow in laboratory settings. To obtain accurate and reliable results, it is vital to follow the precise culture conditions required for each bacterial strain. The evaluation of ORC highlighted its potential to inhibit bacterial growth, showing promising results against various bacterial strains and Candida albicans. Different variants of ORC, such as Regecel, have demonstrated impressive capacity to hinder the growth of 32 distinct bacterial strains, with inhibition rates ranging from 40-100%. These bacteria include methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE), and penicillin-resistant Streptococcus pneumoniae. This study supports the usage and development of ORC (Regecel) as an innovative approach to treating bacterial infections.

Promoting the healing of infected diabetic wound by nanozyme-containing hydrogel with anti-bacterial inflammation suppressing, ROS-scavenging and oxygen-generating properties.

Bacterial infections already pose a significant threat to skin wounds, especially in diabetic patients who have difficulty healing wounds. However, wound or bacterial infections are known to produce excess reactive oxygen species (ROS), and hypoxia may further hinder wound healing and the development of chronic wounds. In this study, a multifunctional hydrogel for ROS scavenging and bacterial inhibition was developed by cross-linking polyvinyl alcohol (PVA) and sodium alginate (SA) with graphene oxide (GO) loaded with silver-platinum hybrid nanoparticles (GO@Ag-Pt). The PVA/SA hydrogel loaded with GO@Ag-Pt exhibited the ability to scavenge different types of ROS, generate O2, and kill a broad spectrum of bacteria in vitro. The silver-platinum hybrid nanoparticles significantly increased the antibacterial ability against Escherichia coli and Staphylococcus aureus compared with silver nanoparticles (AgNps). GO@Ag-Pt loaded hydrogel was effective in treating infections caused by S.aureus, thereby significantly promoting wound healing during the inflammatory phase. Hydrogel therapy significantly reduced the level of ROS and alleviated inflammation levels. Notably, our ROS-scavenging, antibacterial hydrogels can be used to effectively treat various types of wounds, including difficult-to-heal diabetic wounds with bacterial infections. Thus, this study proposes an effective strategy for various chronic wound healing based on ROS clearance and bacteriostatic hydrogels.

Platelet-Rich Plasma in Aesthetic Dermatology: Current Evidence and Future Directions.

Platelet-rich plasma (PRP) has emerged as a promising treatment in aesthetic dermatology. This systematic review aims to evaluate the current evidence for PRP applications in skin rejuvenation, hair restoration, wound healing, and fat grafting. FollowingPreferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, a comprehensive literature search was conducted across multiple databases and 13 studies meeting the inclusion criteria were selected for review. The Mixed Methods Appraisal Tool (MMAT) was used to assess the quality of included studies. The reviewed studies consistently reported positive outcomes for PRP across various applications. In skin rejuvenation, significant improvements in collagen density and overall skin appearance were observed. For hair restoration, studies showed mean increases of 18-27.7 hairs/cm² in treated areas. PRP demonstrated efficacy in accelerating wound healing across various wound types, including chronic ulcers. In fat grafting, PRP was associated with improved graft survival and integration. Patient satisfaction was generally high across all applications. However, there was significant heterogeneity in PRP preparation methods and treatment protocols among studies. This systematic review provides evidence supporting the efficacy of PRP in aesthetic dermatology, particularly in skin rejuvenation, hair restoration, wound healing, and fat grafting. PRP demonstrates a favorable safety profile across applications. However, the variability in study designs and PRP protocols highlights the need for standardization. Future research should focus on large-scale randomized controlled trials with standardized protocols and longer follow-up periods to solidify the evidence base for PRP in aesthetic dermatology.

Design of a clinical study to demonstrate the therapeutic benefit of another wound treatment product

Due to new legal requirements, a patient-relevant benefit for other wound treatment products (sPW) must be demonstrated through clinical studies if reimbursement at the expense of the statutory health insurance is sought in the non-inpatient sector. An interdisciplinary group with expertise in clinical wound care has developed general recommendations for the design of suitable studies. In addition to regulatory documents, previous studies that have already been recognized as proof of benefit in other areas served as a basis. Randomized controlled trials that cover at least the most common types of chronic wounds (arterial, venous, diabetic or pressure sore) are recommended as the best method for gathering evidence. Despite the heterogeneous etiology of chronic wounds, the results should also be transferable to other wound types. The test intervention does not usually consist of the sPW alone, but of a combined wound treatment that follows a treatment plan that is as clearly defined as possible. In the comparison group, all wound treatment options (besides the sPW) must also be available and used according to a similar predefined treatment plan. Depending on the intended purpose and treatment goal, complete wound closure should, if possible, be recorded as the cardinal - although not always as the primary - endpoint. In justified cases, e.g. in the case of intermediate use as part of phase-appropriate wound therapy for chronic wounds, a significant reduction in the wound area can also be considered for benefit assessment. Quality of life (e.g. pain) can also justify a benefit and can therefore be recorded as a primary outcome parameter in clinical trials. The duration of the clinical trial should be adapted to the central endpoints, the medical or nursing goal of wound care and the intended purpose of the sPW. A benefit does not always arise from microbiological, physiological, laboratory or histological parameters or imaging findings.

End-of-Life Skin Changes: Make Sure You Know What They Mean, a Case Study

Skin is the largest organ of the human body. Skin changes can result from natural ageing, as well as from acute or chronic diseases and failure of body systems. Various types of wounds are identified in Palliative Care, and terminal pressure ulcers are often incorrectly classified. This case study highlights the importance of recognizing skin ulcers in patients’ last hours and days of life as a diagnostic indicator for impending death. The first focus of nursing care was pain management and maintaining skin integrity. On the 20&lt;sup&gt;th&lt;/sup&gt; of December 2023, a pressure ulcer was identified on a patient in the sacral region with unknown further characteristics. A skin modification was observed three days later in the neck area, with intense redness and no heat felt. Approximately ten minutes later, several minor purple-type discolorations, like small bruises, appeared on the chest area as a symmetrical mirror image. This change suggested a Trombley-Brennan Terminal Tissue Injury. The patient died 14 hours after the first skin change was observed on the neck. After examining this case study, it becomes clear that it is essential to expand knowledge and actively involve nurses in the accurate assessment and classification of skin changes, especially regarding Kennedy Terminal Ulcers or Trombley-Brennan Terminal Tissue Injuries, as they are indicators of death’s proximity.

Optimal Multiple Wind Power Transmission Schemes Based on a Life Cycle Cost Analysis Model

Due to the high cost and complex challenges faced by offshore wind power transmission, economic research into offshore wind power transmission can provide a scientific basis for optimal decision-making on offshore wind power projects. Based on the analysis of the topology structure and characteristics of typical wind power transmission schemes, this paper compares the economic benefits of five different transmission schemes with a 3.6 GW sizeable onshore wind farm as the primary case. Research includes traditional high voltage alternating current (HVAC), voltage source converter high voltage direct current transmission (VSC-HVDC), a fractional frequency transmission system (FFTS), and two hybrid DC (MMC-LCC and DR-MMC) transmission scenarios. The entire life cycle cost analysis model (LCCA) is employed to thoroughly assess the cumulative impact of initial investment costs, operational expenses, and eventual scrap costs on top of the overall transmission scheme’s total cost. This comprehensive evaluation ensures a nuanced understanding of the financial implications across the project’s entire lifespan. In this example, HVAC has an economic advantage over VSC-HVDC in the transmission distance range of 78 km, and the financial range of a FFTS is 78–117 km. DR-MMC is better than the flexible DC delivery scheme in terms of transmission capacity, scalability, and offshore working platform construction costs in the DC delivery scheme. Therefore, the hybrid DC delivery scheme of offshore wind power composed of multi-type converters has excellent application prospects.

Platelet-rich plasma and plasma rich in growth factors in extra-oral wound care.

This narrative review evaluates the existing literature on the clinical efficacy and safety of platelet-rich plasma (PRP) and plasma rich in growth factors (PRGFs) in extra-oral wound care, considering their potential benefits and drawbacks. The review specifically focuses on the impact of these treatments on patients' quality of life, pain management, treatment costs, recurrence rates, and potential complications. Given the extensive literature and diverse range of extra-oral wound types in which these autologous platelet concentrates have been applied, this narrative review focuses on the most frequently described wound types, including diabetic foot ulcers, venous leg ulcers, pressure ulcers, surgical wounds, and burns. The use of PRP has been reported in various medical specialties, with a low risk of adverse events. While there is a growing interest in the use of PRGF with promising results, the available literature on this topic is still limited. Only a few studies evaluated patients' perception of the treatment and the relationship between treatment costs and clinical outcomes. Data on recurrence rates and complications also vary across studies. In conclusion, PRP and PRGF show promise as alternatives or as adjunctive therapies to conventional treatments for various extra-oral wounds and ulcers, leading to reduced wound size and accelerated healing time but should be considered on a case-by-case basis, taking into account the type and severity of the wound.