Types Of Dermatoses Research Articles

Patch testing with Indian standard series of 20 allergens in 125 patients of chronic dermatitis and dermatoses

Objectives: Patch testing is generally done in cases of allergic contact dermatitis to find the offending allergen/s. It has been less reported in patients clinically presenting as non-eczematous contact reactions such as lichen planus, lichenoid eruption, lichen planus pigmentosus and facial melanosis overlap. In addition, it may give clues to the sensitizers leading to chronic, recurring dermatitis and overlap of dermatoses in the form of systemic contact dermatitis. The aim of the present study was to identify the sensitizer/s with patch testing in patients presenting with non-eczematous contact reactions as well as chronic, relapsing dermatitis and overlap of dermatoses. Material and Methods: In the present study, patch testing was done using the Indian standard series in 125 cases presenting clinically as lichen planus, lichen planus pigmentosus, facial melanosis, cheilitis, mucosal lichen planus and vulvar dermatitis, in addition to cases of chronic and recurrent dermatitis such as nummular eczema, lichenoid eruption, pompholyx, photo aggravated dermatitis, air borne contact and hand and feet dermatitis. Results: The tests were positive in 102 (81.6%) patients, negative in 16, doubtful in 3 and invalid in 4 patients. Positive results were found in 100% cases of photo aggravated dermatitis and chronic dermatitis of hands/feet dermatitis and 76% cases of facial melanosis and lichen planus pigmentosus overlap, 88.9% cases of nummular eczema, 81.8% cases of lichenoid eruption, 75% cases of lichen planus, 57% cases of atopic eczema, 66.6% cases of pompholyx, and 100% of mucosal lichen planus. Test for nickel was positive in 40 (32%) cases, parthenium in 37 (29.6%), cobalt in 23 (18.4%), fragrance in 19 (15.2%), paraphenylenediamine in 17 (13.6%), paraben in 9 (7.2%) and neomycin in 5 (4%) cases, either alone or in combination. In the present study, in addition to eczematous dermatoses, non-eczematous conditions such as lichen planus, lichenoid eruption, lichen planus pigmentosus and facial melanosis also showed positive results on patch testing. Conclusion: Patch testing should be considered in patients presenting with chronic and recurrent dermatitis and overlap of more than one type of dermatoses. Identification and elimination of culprit allergens can help in achieving long term remission in these chronic conditions.

Management of pain in the inpatient and non-surgical outpatient dermatology settings: A narrative review.

Pain is frequently encountered in dermatology practice, which impairs the activities of daily living, adds to psychological morbidity, and therefore compromises the quality of life. It ranges from mild to severe in intensity across various dermatoses and requires prompt addressal and treatment. Diseases such as extensive pemphigus vulgaris and Stevens-Johnson syndrome are especially painful and require a multidisciplinary approach with the involvement of a pain specialist in their management. The main pathogenic types of pain include visceral nociceptive, somatic nociceptive, and neuropathic types, the latter two being most relevant in dermatological disorders. Somatic nociceptive pain is often seen in patients of Stevens-Johnson syndrome/ Toxic epidermal necrolysis, epidermolysis bullosa, pemphigus vulgaris, erythema nodosum, and hidradenitis suppurativa, while neuropathic pain is part of the disease process in dermatoses like leprosy, herpes zoster, and dysesthesia syndromes. Therapeutic approaches to pain management include the use of non-opioids (acetaminophen, non-steroidal anti-inflammatory agents), opioids, and non-pharmacological therapies, along with appropriate management of the underlying dermatosis. World Health Organisation (WHO) analgesic ladder remains the most commonly employed guideline for the management of pain, although treatment needs individualisation depending on the nature and severity of pain (acute/chronic), type of dermatosis, and patient factors. There is a paucity of literature pertaining to pain management in dermatology and this topic is often neglected due to a lack of awareness and knowledge of the topic. The present review aims to discuss the pain pathway, various painful conditions in the setting of medical dermatology practice, and their management along with relevant pharmacology of the commonly used analgesics.

Cutaneous Manifestations of Diabetes Mellitus in a Tertiary Care Hospital in Eastern India: A Cross-sectional Study

Background: Diabetes mellitus is a chronic metabolic disorder and is a major public health problem worldwide. Skin diseases can appear as the first sign of diabetes or can develop at any time in the course of the illness. Purpose: This study aimed to determine the pattern and prevalence of skin manifestations in patients with diabetes mellitus. Methods: An observational cross-sectional study was done on 80 Type 1 and Type 2 diagnosed diabetes mellitus patients and with informed consent, they were thoroughly examined for their respective skin disorders. Results: Among 80 patients, 35% of patients had infectious skin lesions, whereas 20% had noninfectious dermatosis only. More than one type of dermatosis was seen in 45% of patients. Candidal balanoposthitis was the most common fungal infection. Limitation: Limited sample in a single center. Conclusion: Infections were more prevalent compared to noninfectious disease in a population with uncontrolled diabetes mellitus. Pruritus was the most common disorder among the other diabetic complications.

Facial Dermatoses Associated With Mask-Wearing in the COVID-19 Era: A Nationwide, Cross-Sectional, Multicenter, Questionnaire-based Study.

Daily usage of facial masks during coronavirus disease 2019 pandemic influenced on facial dermatoses. This study investigated the impact of mask-wearing habits on facial dermatoses. A nationwide, observational, questionnaire-based survey was conducted from July through August 2021, involving 20 hospitals in Korea. Among 1,958 facial dermatoses, 75.9% of patients experienced aggravation or development of new-onset facial dermatoses after wearing masks. In aggravated or newly developed acne patients (543 out of 743), associated factors were healthcare provider, female gender, and a long duration of mask-wearing. Irritating symptoms, xerosis, and hyperpigmentation were more frequently observed in this group. Aggravated or newly developed rosacea patients (515 out of 660) were likely to be female, young, and have a long duration of mask-wearing per day. Seborrheic dermatitis patients who experienced aggravation or de novo development (132 out of 184) were younger, and they more frequently involved the chin and jaw in addition to the nasolabial folds and both cheeks. Contact dermatitis patients (132 out of 147) with aggravation or de novo development tended to be female, involve both cheeks, and complain of pruritus. Aggravated or newly developed atopic dermatitis patients (165 out of 224) were more likely to be female, and had a higher baseline investigator global assessment score before mask-wearing. Clinical features and factors related to aggravation were different according to the types of facial dermatoses.

Unilateral Vulvar Pyoderma Gangrenosum: A Case Report

Pyoderma gangrenosum (PG) is a rare, chronic, relapsing, ulcerative neutrophilic dermatosis type with a peculiar morphologic presentation. PG of the vulva is extremely rare, and unilateral involvement of the vulva has not been previously reported. We present herein a case of unilateral PG of the vulva in a 22-year-old female patient. The patient responded excellently to treatment with oral prednisolone 40 mg/day tapered over 3 weeks, combined with azathioprine 50 mg thrice a day from the 10th day of treatment.

Gottron’s Carcinoid Papillomatosis: Case Report

Introduction. Gottron’s papillomatosis is a rare benign type of dermatosis with pseudoepitheliomatous hyperplasia of the epidermis, first described as an independent disease by the German dermatologist H.A. Gottron. Invasive epidermal growth and hyperkeratosis reveal no signs of malignancy. Chronic venous insufficiency and lymphedema can be associated with various secondary skin lesions: the formation of ulcers, hyperkeratosis and skin papillomatosis, as well as infectious complications. Skin papillomatosis may be a manifestation of paraneoplastic syndrome, which requires a careful differential diagnosis. Timely treatment of complications in a patient with concomitant somatic pathology performed by a multidisciplinary team of specialists is necessary to improve the prognosis. Considering the relative rarity of Gottron’s papillomatosis and the lack of awareness among practicing physicians regarding the differential diagnosis of this disease, we present this clinical analysis.Description of a clinical case. Patient L., 42 years old (body mass index — 76.5 kg/m2) with chronic lymphovenous insufficiency, lymphedema, erysipelas of the right lower limb associated with unspecified skin papillomatosis, was urgently hospitalized in a health care institution “City Clinical Hospital No. 3” of Grodno (Republic of Belarus), consulted by a multidisciplinary team of clinicians including a therapist, a cardiologist, a dermatologist, an endocrinologist, an infectious disease specialist, and a surgeon. Taking into account the clinical status of the patient and the retrospective analysis of archival records of previous examinations performed on the patient in the health care institution “Grodno University Clinic”, the type of dermatosis was determined as Gottron’s papillomatosis of both lower extremities. In terms of the clinical diagnosis of the patient, complex therapy was initiated in a hospital setting, which was then continued at the outpatient stage.Conclusion. Adequate long-term treatment of morbid obesity and chronic lymphovenous insufficiency is necessary to prevent serious complications. According to the academic literature, timely diagnosis of such a rare dermatosis as Gottron’s papillomatosis, as well as the prescription of adequate therapy determine the possibility of regression in the early stages of the disease.

A cross-sectional study on the prevalence and determinants of various neonatal dermatoses.

During the neonatal life cycle, various dermatological conditions are common. In comparison to the skin of adults, neonates' skins are more susceptible to infections in the first week of their lives. These infections often lead to many dermatological skin complications and create worrisome among parents. Hence, it is crucial to diagnose and manage such affected neonates at the earliest. This study aimed to highlight and estimate the occurrence of numerous dermatoses and assess various skin changes that occurred physiologically and pathologically in neonates. In this cross-sectional observational study, 474 neonates were enrolled in the neonatal intensive care unit. The whole newborn skin surface, comprising the palms and soles, scalp, mucous membranes, genitalia, hair, and nails, was scrutinized under adequate light, and all changes that occurred over the skin were observed and recorded. The sample size estimation was undertaken from the references that have the least prevalent cutaneous dermatosis: hypertrichosis desquamation and napkin dermatosis. A statistical analysis like the Chi-square test was performed to associate the type of dermatosis with the parameters of age, gender, delivery type, and birth weight. Of the total 474 cases, 90 (18.98%) had single dermatosis, while the remaining 384 (81.01%) had more than one form of dermatosis. Among the 384 cases, sebaceous gland hyperplasia (SGH) in 105 (22.15%), Epstein pearls in 50 (10.54%), erythema toxicum neonatorum (ETN) in 40 (8.43%), physiological desquamation in 25 (5.27%), lanugo hair in 20 (4.21%), miliaria in 22 (4.64%), salmon patch in 13 (2.74%), cradle cap/seborrheic dermatitis in 6 (1.26%), vernix caseosa in 12 (2.53%), transient neonatal pustular melanosis in 13 (2.74%), congenital melanocytic nevus in 20 (4.21%), hemangioma in 15 (3.16%), neonatal acne in 5 (1.05%), napkin dermatitis in 10 (2.10%), cutis marmorata in 6 (1.26%), milia in 2 (0.42%) intertrigo 3 (0.63%), collodion baby in 2 (0.42%), and neonatal occipital alopecia in 2 (0.42%) neonates each and others, respectively. The findings from the present study were representative of a specific racial/geographic distribution and will assist in adding or comparing the prevalence of neonatal dermatosis with other geographic regions as the array of dermatological characterizations in neonates varies as per time and place. This study aims to provide insight into the future implications in the neonatal dermatology domain and avoid further skin complications.

Частота развития дисфункции мейбомиевых желез у детей с некоторыми видами хронических дерматозов

In order to investigate frequency of occurrence and features of the clinical course of dry eye syndrome (DES) in children of various ages with certain types of chronic dermatoses, 80 patients aged 4 to 17 years were examined. The criteria for their inclusion in the study were the presence of a verified diagnosis of atopic dermatitis (in the acute stage) (60 children) or ichthyosis (vulgar and congenital) (20 children). All were examined for the severity of subjective discomfort, the condition of the ocular surface, the production and stability of the pre-corneal tear film. The results obtained indicate the presence of clinical and functional signs of DES (mainly due to dysfunction of the meibomian glands) in 41 children (68.3 %) with atopic dermatitis and 15 (75.0 %) with ichthyosis. At the same time, in children with the studied types of chronic dermatoses, DES occurred mainly in mild and moderate forms. It is advisable to conduct an examination of patients with other forms of chronic dermatoses in order to identify and treat their meibomian gland dysfunction and the associated dry eye syndrome. Keywords: dysfunction of the meibomian glands, dry eye syndrome, chronic dermatoses, atopic dermatitis, ichthyosis.

Clinical value of [18F]F-FDG PET/CT in patients with suspected paraneoplastic dermatoses: Diagnostic performance and impact on clinical management

PurposeWe retrospectively evaluate the diagnostic performance of 2-deoxy-2[18F]fuoro-D-glucose([18F]F-FDG) PET/CT and its impact on clinical management in patients with suspected paraneoplastic dermatoses (PD). Materials and MethodsFrom an institutional PET/CT database (2014–2022), we retrospectively analyzed patients who were clinically suspected with PD and underwent [18F]F-FDG PET/CT for screening an underlying malignancy. For all scans, positive mucocutaneous lesions and PET-indicated malignancies were assessed, and the degree of FDG avidity among different dermatoses were quantified. The final diagnoses of dermatoses and neoplasms were based on pathologic results, international diagnostic standard and follow-up. We assessed the recommended and applied therapies before and after [18F]F-FDG PET/CT and noted whether the patient management changed on the basis of the [18F]F-FDG PET/CT results. ResultsWe analyzed 60 patients with 10 types of dermatoses in this study. Finally, 19 of the 60 patients who had both of specific dermatosis and contemporaneous neoplasm were diagnosed with PD. [18F]F-FDG PET could identify the underlying neoplasms in 18/19 (94.7%) PD patients, and led to a change of the management in 9/19 (47.4%) PD patients. In addition, the mucocutaneous manifestations of [18F]F-FDG PET/CT associated with several specific dermatoses were characteristic. ConclusionsThis study highlighted the value of [18F]F-FDG PET/CT as a useful tool for evaluation of patients with suspected PD to unveil the underlying culprit tumor, and profoundly supports the clinical management of PD patients.

Pattern of pediatric dermatoses in a tertiary hospital in South India

Background: Several cross-sectional studies in the form of school surveys and studies on paediatric patients visiting dermatology OPD in tertiary care hospital has been conducted in the last three decades. This study was conducted to note the pattern of paediatric dermatoses and also to compare the difference in disease pattern with other studies conducted in southern India in last decade. Methods: A retrospective cross-sectional study was conducted at the Dermatology department of MVJ teaching hospital to determine the pattern of pediatric dermatoses from May 2021 to October 2021 after obtaining institutional ethics committee clearance. Cases under the age of 18 years were included in the study. Cases with age above 18 years, incomplete data, dermatoses where diagnosis was uncertain were excluded from the study. A total of 150 children were included in the study. The results were entered and tabulated in MS-excel sheet and descriptive analysis was done. Results: 150 children were included in the study.36 types of dermatoses were noted overall. Eczematous diseases (32.7%) contributed to the maximum followed by infections and infestations (25.3%). The most frequent dermatoses found were Atopic dermatoses (10%), pityriasis alba (8.6%), scabies (8.6%), Acne vulgaris (8.6%). Eczematous diseases and hypersensitivity disorders were noted to have increased frequency when compared to other studies in last one decade Conclusions: Rising trend in atopic dermatitis has been noted which might be due to changing environmental factors and also due to better recognition of condition by physicians in last one decade. With respect to spectrum of skin infections and infestations not much of difference is appreciated when compared to previous studies

Prevalence and Clinical Aspects of Dermatoses Among Hairdressers in the City of Parakou in 2021

Introduction: Hairdressing is a profession that exposes people to many products responsible for dermatoses. The objective of this study was to determine the prevalence and the different types of dermatoses observed among hairdressers in the city of Parakou. Method: This was a descriptive and analytical cross-sectional study of hairdressers in the city of Parakou using probability sampling. The data were analyzed with the Epi-info7.2.2 software. The comparison of frequencies was done with the Pearson Chi2 statistical test and the significance threshold was set at p strictly less than 5%. Results: A total of 77 hairdressers had dermatoses out of 360 surveyed. The average age was 22.81 +/-8.14 years with extremes of 10 and 52 years. The sex ratio was equal to 0.56. The hand was the most affected area (61.04%). Macular and papular lesions were the most common (29.87%). The most frequent dermatoses were contact dermatitis (10.21%) with 4.72% of wear and tear dermatitis, 4.45% of irritation dermatitis and 1.11% of allergic contact dermatitis, acne (5%) and ungual damage (1.67%). Conclusion: The prevalence of dermatitis among hairdressers is not negligible in Parakou. Communication sessions for a continuous change of behavior would certainly contribute to the reduction of the latter.

Mask-related Facial Dermatoses in an Asian Pediatric Population in the Era of COVID-19 Pandemic: A Cross-sectional Study

Abstract Introduction: Mask-related dermatoses have been widely reported in adults since the global COVID-19 pandemic. Compulsory mask wearing has been mandated in many countries. As pediatric dermatologists, we aim to characterize different types of mask-related dermatoses in the pediatric population, evaluate the prevalence, and potential exacerbating and mitigating factors to improve compliance in children in this era of regular mask wearing. Methods: We conducted a cross-sectional study from November 1, 2020, to January 31, 2021, at a tertiary hospital in the form of an anonymous online questionnaire. This included all children aged (2–20 years old) in our pediatric dermatology clinics, tertiary education students (16–20 years old), and children of hospital/health-care cluster staff (2–20 years old). Results: Of the 577 participants who reported regular mask wearing, 140 (24.3%) reported symptoms. The most common symptoms were itching (74.5%), dryness (49.6%), dyspnea (32.1%), and oily skin (29.9%). The most common rashes were acne (48.9%), eczema (27%), dryness/peeling (23.4%), urticaria (18.2%), and cheilitis (16.8%). The most statistically significant risk factors for developing mask-related symptoms and/or rashes were (a) prolonged duration of mask wearing/day and (b) preexisting dermatoses and/or atopic history (especially atopic dermatitis). Conclusions: As the pediatric population remains vulnerable to emerging COVID-19 variants and other respiratory viruses, masks remain an important form of protection in daily life. Like in adults, regular mask wearing can lead to various facial symptoms/dermatoses in pediatric wearers, adding to dermatological burden during a pandemic. Those with preexisting risk factors should be made aware of this. We recommend all pediatric mask wearers should not exceed continuous mask wearing for 4 h and to take scheduled “mask breaks” in safe, well-ventilated areas.

A cross-sectional study to document socio-demographic profile and disease profile of dermatosis in pediatric age group

Background: Skin diseases are considered a major health problem in the pediatric age group and are sometimes associated with significant morbidity. Among them, dermatosis is one of the most common skin diseases in India, affecting the skin and hair. Early diagnosis and treatment are essential for pediatric patients to prevent long-term persistence or disability caused by the disease. Although some manifestations are physiological and require no treatment, different age groups have different sets of clinical dermatoses, with dermatitis being the most common among all age groups. Studying the proportions of various clinical presentations of different types of dermatosis helps in the proper diagnosis and management of patients. This study was conducted to document the socio-demographic profile and disease profile of various forms of pediatric dermatosis. Methods: A cross-sectional study was conducted from April 2017 to March 2019 among 401 pediatric patients at a tertiary-level hospital. Results: Out of the 401 participants, approximately two-thirds were male, and more than half (53.1%) were 5-11 years old. Among the dermatoses groups, the most common were dermatitis (20.4%), nutritional (15%), pigmentary (13.6%), and others. Conclusions: All forms were predominantly seen among males, except in a few dermatitis types like papulosquamous, hair, pigmentary, bullous, and keratinizing disorders, where females were more prone than males.

Three cases of subcorneal pustular dermatosis with immunohistochemical examinations.

Subcorneal pustular dermatosis, a rare, benign skin disease, is a type of neutrophilic dermatosis. The authors reported three cases of subcorneal pustular dermatosis. In case 1, a 9-year-old girl developed a skin rash with blisters following a mycoplasma infection and had a flare-up due to a common cold. She was successfully treated with a topical corticosteroid. In case 2, a 70-year-old woman who had been treated for rheumatoid arthritis with adalimumab, salazosulfapyridine, and leflunomide developed 3- to 5-mm pustules on her trunk and thighs 4 days after flu vaccination. The rash disappeared with drug withdrawal and treatment with diaminodiphenyl sulfone. In case 3, an 81-year-old man, who was diagnosed with pyoderma gangrenosum at 61 years old, developed multiple small flaccid pustules on his trunk and extremities due to an infection in the arteriovenous shunt area on the forearm. The pustule disappeared with intravenous antibiotic therapy; however, the pustules subsequently flared up along with ulcers typical of pyoderma gangrenosum. He was given oral prednisolone therapy, which was effective for the small pustules and some ulcers. Immunohistochemical examination of the three cases revealed neutrophilic infiltration in the subcorneal layer of the epidermis. The pustules contained neutrophils as well as some CD68+ and a few CD1a+ cells. The epidermis and dermis were more predominantly infiltrated by CD4+ cells than by CD8+ cells. Positive stainings for interleukin 8, interleukin 36γ, and phospho-extracellular signal-regulated kinases 1 and 2 were observed in the upper layers of the epidermis below the pustules. Although the pathogenesis of subcorneal pustular dermatosis has not been clarified, the current results suggest that a variety of inflammatory cells, including those responsible for both innate and acquired immunity, are involved in the accumulation of neutrophils in subcorneal pustular dermatosis.

Дисфункция мейбомиевых желез у детей с некоторыми видами хронических дерматозов

In order to investigate the possible presence and features of the clinical course of dry eye syndrome (DES) in children of various ages with certain types of chronic dermatoses, 65 patients aged 4 to 17 years were examined. The criteria for their inclusion in the study were the presence of a verified diagnosis of atopic dermatitis (in the acute stage) (48 children) or ichthyosis (vulgar and congenital) (17 children). All were examined for the severity of subjective discomfort, the condition of the ocular surface, the production and stability of the pre-corneal tear film. The results obtained indicate the presence of clinical and functional signs of DES (mainly due to dysfunction of the meibomian glands) in 31 children (64.6%) with atopic dermatitis and 14 (82.4%) with ichthyosis. At the same time, in children with the studied types of chronic dermatoses, DES occurred mainly in mild and moderate forms. It is advisable to conduct an examination of patients with other forms of chronic dermatoses in order to identify and treat their meibomian gland dysfunction and the associated dry eye syndrome. Keywords: dysfunction of the meibomian glands, dry eye syndrome, chronic dermatoses, atopic dermatitis, ichthyosis

Cytokine profile of the epidermis is region specific and may determine the characteristics of inflammation.

Recent data indicate that distinct skin areas show different microbial/chemical milieu. Keratinocytes (KC) respond to these stimuli by producing cytokine mediators. Therefore, we aimed to determine KC-derived cytokine expression in distinct healthy skin regions (gland-poor [GP], sebaceous gland-rich [SGR] and apocrine gland-rich [AGR]), and their changes in skin diseases of the given regions (atopic dermatitis [AD], papulopustular rosacea [PPR] and psoriasis). Cytokines were analysed at the mRNA and protein levels, and literature analysis was performed for functional categorization. The three regions showed characteristically different cytokine patterns. GP was featured by an IL-25/IL-33/IL-36RA/IL-38/IL-18 cytokine milieu, SGR was characterized by IL-23/IL-17C/IL-18, and AGR skin exhibited a mixed IL-25/IL-33/IL-23/IL-18 profile. Literature analyses revealed different homeostatic and proinflammatory roles of these cytokine patterns (Th2 related in GP, Th17 related in SGR and mixed Th2/Th17 in AGR). In skin diseases which are primarily epidermal cytokine-driven (AD, PPR), the level of the regionally characteristic cytokines were further elevated, in contrast to the autoantigen-driven psoriasis, where the cytokine pattern was independent from the localization. Healthy skin regions are equipped with different KC-derived cytokine profiles, which may influence each region's capability of mediator production in certain types of dermatoses.

Adverse effects of phototherapy: A review

It's very fortunate that skin diseases are treated and can be cured not only by the use of drugs but by applying the medicines topically and some therapies are very much effective. These therapies can be used after applying drugs and without drugs as well. Phototherapy is also an emerging branch of photobiology which are frequently used in treating various skin conditions. It now has become a popular way of treating various skin conditions like psoriasis, vitiligo and several types of dermatoses. Phototherapy which was started through natural means like sunlight in the treatment of vitiligo by Egyptians now has become advanced where several types of light of various wavelengths are being used to treat diseased skin conditions. After frequent and common use of these phototherapeutic options scientists have come across various adverse effects of phototherapy. So some protocols and SOPs have evolved for better outcomes and lesser side effects. The common adverse effects encountered are sunburn, erythema, pruritus, dry skin, and various types of dermatoses. These side effects are very much common after applying photosnsitizing drugs like psoralens. Besides these bad effects ocular and GIT-related side effects are also found. The most grievous adverse reactions are skin cancers which must be addressed. Here in this review, we are discussing some of them so as to avoid them and phototherapy can be used in a better way.

Epidemiological profile of tumor dermatoses in the hospital setting in Cotonou (Benin) from 2009 to 2018

Introduction Tumoral dermatoses are tissue neoformations due to an excessive, abnormal, anarchic and more or less autonomous cellular proliferation at the expense of the skin and its appendages. These tumoral dermatoses can be benign or malignant. They are responsible for a high morbi-mortality. Patients and methods Retrospective and descriptive cross-sectional study of the records of patients seen for mucocutaneous tumors, in the Dermatology-Venereology Department of the National Hospital and University Center Hubert Koutoukou Maga (NHUC-HKM) of Cotonou, from 2009 to 2018. Epidemiological data were collected from consultation registers and then entered and analyzed with Excel, EPI-DATA and SPSS software. Results A total of 10,627 new patients were registered, of which 885 cases of tumor dermatoses (8.32%). Thirty-five types of tumor dermatoses were collected. The average age was 31 years; the most represented age group was 20-39 years (46.30%). The sex ratio was 1.02. Lesions were acquired in 93.30% of patients. Benign tumors represented 94.80% of the patients. They were dominated by keloids (24.60%) followed by condylomas (16.20%), warts (10.40%), molluscum contagiosum (7.60%), cysts (6.50%) and the group formed by nevi and hamartomas (6.20%). Malignant tumors were rare and represented by carcinomas (basal and squamous cell) with 1.7% and melanoma (0.50%). Kaposi's disease was observed in 2.50%. Conclusion This study allowed us to know the frequency and the different types of tumoral dermatoses observed in the patients followed in the dermatology-venereology department of the NHUC-HKM of Cotonou during the last ten years.

Prevalence, risk factors and types of dermatoses among food handlers in Batticaloa MOH area

Introduction: Batticaloa is the capital city of Batticaloa District situated in Eastern Province of Sri Lanka, which harbors various ethnic groups with different religious backgrounds. The ethnic and religious diversity of population is responsible for variety of food items and dishes unique to the area where demand for food has created a rapidly growing food industry. Food safety standards require all persons involved in handling food to be in perfect hygienic condition in order to prevent contamination with microorganisms and to offer a perfect product to the consumer.
 Methods: A descriptive cross sectional study was carried out among food handlers who were working in the most populated PHI regions of Batticaloa MOH area. All workers were interviewed and examined at their workplace and relevant further examination and investigations were carried out at the Skin Clinic, Teaching Hospital, Batticaloa.
 Results: 69 (42.3%) out of the total 163 workers had occupational dermatoses (OD), and out of them physical injuries (thermal, cuts/ abrasions) was the commonest [22 (31.88%)]. Second commonest OD was paronychia and occupational contact dermatitis (OCD), which was found only among 12 (17.3%) workers. Irritant contact dermatitis (ICD) was more prevalent (11.5%) than allergic contact dermatitis (ACD) (5.7%) among the workers with OCD. Both personal history of atopy and increased frequency of hand washing were positively correlated with the risk of developing OCD. Acne vulgaris was the commonest none occupational dermatoses (NOD).
 Conclusions: Both personal history of atopy and increased frequency of hand washing were positively correlated with the risk of developing OCD. Physical injuries remained the commonest OD which may be contributed by lack of experience and substance abuse.

317 When Diagnosis Becomes a Challenge

Erythema dyschromicum perstans (EDP) or ashy dermatosis is a form of an acquired dermal macular hyperpigmentation. The etiology of this disease is still unknown. Often encountered in young adults, this type of dermatosis can sometimes occur in children. Women are affected more frequently than men. We report the case of a 35-year-old male patient with Fitzpatrick skin type III, non- smoker, with no occupational exposure to toxic substances. The patient has no significant family or personal pathological history and he denies drug use.