The article analyzes the application of methods of machine learning based on artificial neural networks in applied problems of detection and classification of cyber threats. The topic of gender is associated with a significant increase in the implementation of the information technology and cybersecurity technologies of the machine learning. The interdependence between the concepts of “artificial intelligence”, “machine learning”, “deep learning” is revealed. In the article, according to the results of the information sources analysis, the main methods of ML, which have been used in the field of cybersecurity, as follows: Bayes’ networks, artificial neural networks, support vector machine, fuzzy logic, and others are highlighted. A brief analysis of methods for detecting cybersecurity threats using information security and cybersecurity, as follows: statistical, signature, heuristic and abnormal detection methods, has been carried out. The general characteristic is given and the advantages and problems that solve the ML methods for the detection of abnormal events are outlined. The paper considers the main types of artificial neural networks that are used in the tasks of detecting cyber threats. In the article, the basis for considering the general application of machine learning methods is taken by artificial neural networks based on multilayered perceptron with a backpropagation. The general structure of artificial neural networks is selected and the basic mathematical expressions of its functioning are presented, the basic types of activation functions of artificial neurons are considered, the general mathematical expression of the calculation cost function for unsupervised machine learning is presented. More substantially consider the issues of the input data choice for systems machine learning (artificial neural networks). It is proposed to use informative data of attack compromise indicators as input to machine learning systems (artificial neural networks). The main data that can be used by the monitoring subsystem of information security and cyber defense can be used to perform detection, classification and forecasting incidents of cybernetic security. The main stages of the process of data processing and detection of cybersecurity incidents using the (artificial neural networks) are identified. The main systems of information protection and cybersecurity in which machine learning systems are implemented are described. According to the results of the article, the main implementation problems of the machine learning methods in the information security systems are highlighted, the main directions of further scientific research are outlined. This work can be used to highlight the subject area during the development and implementation of machine learning technologies in information security and cybersecurity systems
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