Carboxymethyl lysine (CML), an advanced glycation end product (AGE), is formed in food systems due to processing conditions employed. Dietary AGEs, when ingested, add to the endogenous AGEs pool and can have health consequences. Hence, in the present work, traditionally consumed foods from India were determined for bound and free CML levels formed by various cooking methods. Ultra-high performance liquid chromatography-mass spectrometry (UHPLC-MS/MS) with multiple reaction monitoring (MRM) was used to estimate the levels of CML for various food categories. In each category among the products tested, milk peda (Indian sweet) had a high amount of CML (230.4 ± 14.65 µg/g). Some of the food products which had significant amounts of CML are Panipuri (24.12 ± 0.35 µg/g), Curd rice (16.70 ± 2.05 µg/g), Pakoda (27.35 ± 4.71 µg/g), and roasted peanut (25.77 ± 2.79 µg/g). Correlating dietary CML consumption with various health parameters would help predict disease outcomes based on eating habits in the long run.
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