JUNO is a 20 kt liquid scintillator detector located ∼650 m underground in Jiangmen, China. The construction will be finished in 2023. Its energy resolution can reach 3% at 1 MeV, which allows it to realize its main goal of determining the neutrino mass ordering (NMO) detecting antineutrinos from two nuclear power plants at 53 km baseline. Mass ordering is expected to have 3 σ of significance in 6 years of data taking. Meanwhile the measurement of oscillation parameters sin2 θ 12, , and will reach sub-percent precision. The Taishan Antineutrino Observatory will be placed ∼30 m from the core of one power plant, in order to measure the reactor antineutrino spectrum, as a reference spectrum for the determination of NMO in JUNO, with resolution better than 2% at 1 MeV. The OSIRIS pre-detector is designed to monitor the LS of JUNO during the several months of filling. With its massive LS volume and excellent energy resolution, JUNO will be able to explore many other neutrino, astro, and particle physics topics. For example, detection of supernova neutrinos, atmospheric neutrinos, solar neutrinos, and geoneutrinos. This paper reviews the current status of JUNO and introduces recent studies on JUNO’s potential in many different physics topics.