In this work, the effects of various wall speed ratios and different heating and concentrating area of the side walls on thermosolutal mixed convection are analyzed. Nine cases are considered depending on the location of heat and concentration sources. Both the horizontal walls are in motion in the same or opposite direction with different speed ratios. A portion of length B of the vertical walls is heated and concentrated uniformly while the remaining parts of these walls are in adiabatic condition. The horizontal walls are considered with cold temperature and low concentration. The governing equations are modeled to describe thermosolutal phenomena. These equations are solved by reconstructing a recently developed compact scheme. To strengthen the analysis performed in this study, we have validated our in-house code with the numerical and experimental data. Computed results are presented in terms of streamlines, isotherms, iso-concentrations, and average Nusselt and Sherwood numbers to evoke the thermosolutal phenomena for various physical parameters. The computed outcomes are scrutinized for different values of the well-defined parameters namely thermal Grashof number (), Prandtl number (), Richardson number (), buoyancy ratio (), wall speed ratios () and Lewis number (). This numerical study has been carried out for different combinations of partially active walls to reveal their effects on heat and mass transfer. It is observed that the thermal and solutal transfer performance becomes effective with maximum wall speed ratios and lower Richardson numbers.