Temporal Cyst Research Articles

Long-Term Outcomes of Temporal Bone Aneurysmal Bone Cysts: Ambispective Study With Systematic Review and Pooled Analysis.

To analyse the clinical, radiological, and surgical management of temporal bone aneurysmal bone cysts (ABCs) and identify factors affecting outcomes. Ambispective study. A single tertiary care institution. This study reviewed 6 cases of temporal bone ABCs treated between 2017 and 2024. Patient demographics, clinical presentation, imaging characteristics, surgical details, and outcomes were collected. A systematic review of the literature was conducted, adhering to Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines, to compare institutional cases with published data. Statistical analyses were performed to identify predictors of treatment success and recurrence. The cohort had a mean age of 27.5 years. Presenting symptoms included scalp swelling, aural fullness, tinnitus, and hearing impairment. Imaging showed expansile lesions with fluid-fluid levels and bone erosion. All patients underwent gross total excision, with a mean intraoperative blood loss of 230.6 ml. One patient experienced temporary grade III facial palsy, which resolved within 3 months. No recurrences were observed during a mean follow-up of 35 months. A pooled analysis of 45 cases from the literature revealed that swelling in the temporal region was the most common presenting feature, and gross total resection was the most frequently employed treatment. Recurrences were rare and typically associated with subtotal resections or advanced-stage tumors. Surgical excision, particularly gross total resection, is the treatment of choice for temporal bone ABCs, with a low recurrence rate. Stage and extent of resection are critical factors in predicting outcomes. This study enhances understanding of the diagnostic and therapeutic approaches for this rare condition.

Dentigerous cysts in horses: A retrospective study

SummaryBackgroundDentigerous cysts are well‐known congenital defects in horses, and the literature on this condition is extensive. Recently, a third type of dentigerous cyst, associated with an exostosis arising from the temporal bone, has been described. Today, computed tomography (CT) is often available and provides detailed information about the exact location and extent of dentigerous cysts, allowing for the description of new findings.Study designThis is a case series outlining the clinical, radiographic and computed tomographic features of dentigerous cysts in seven horses presented to the Equine Clinic at the Vetsuisse Faculty, University of Zurich, Switzerland.ObjectivesThe aim of this case series was to describe the radiographic and computed tomographic findings, and the occurrence of exostoses arising from the temporal bone, in horses with dentigerous cysts.MethodsThe medical records of the Equine Hospital at the University of Zurich were reviewed for horses admitted with dentigerous cysts between 2007 and 2023. Data collected and analysed included patient signalment, clinical history, clinical signs and their duration prior to referral, diagnostic imaging results, treatment and outcomes.ResultsThe most common location for the cysts was the base of the ear, although in one case, the maxillary sinus was involved. Of the seven cases, four were Icelandic horses. CT proved superior to standard radiography for determining the extent and precise location of the cysts, as well as for identifying dental material and exostoses in the temporal region. CT also facilitated detailed surgical planning. All cysts were surgically removed with good long‐term outcomes.Main limitationsOverall, the incidence of dentigerous cysts in horses was low. The relatively high occurrence of dentigerous cysts in Icelandic horses in this study is an interesting finding, though the small sample size calls for further research.ConclusionsTwo of the cases in this series were similar to a recently described variant of a ‘temporal dentigerous cyst associated with an exostosis in the temporal region’ and were closely connected to the bony structure and draining tract.

The Clinical Utility of Finding Unexpected Subclinical Spikes Detected by High-Density EEG During Neurodiagnostic Investigations.

This study aimed to analyze the frequency of unexpected subclinical spikes (USCS) in pediatric patients who underwent high-density electroencephalogram (HD-EEG). Of the 4481 successful HD-EEG studies, 18.5% (829) were abnormal, and 49.7% of these abnormal studies showed SCS, of which 64.1% were USCS. USCS were found to be correlated with attention/concentration deficits and executive dysfunction, often accompanied by the dual psychiatric diagnosis of ADHD. MRI revealed abnormal findings in 32.6% of the subjects with USCS, such as abnormal signal or signal hyperintensity in brain parenchyma, temporal or arachnoid cysts, and vascular malformations. Moreover, the USCS group who received neuropsychiatric testing scored lower than the population mean on Full-Scale Intelligence Quotient, Working Memory Index, and Processing Speed Index. This study highlights the potential of USCS as biomarkers that can lead to changes in clinical management and outcomes, provide valuable information about pathophysiological mechanisms, and suggest potential treatment pathways.

FORENSIC EVALUATION OF SELF-INFLICTED SUICIDES WITH MULTIPLE GUNSHOT WOUNDS

Suicide is a common cause of premature death and a serious social problem. The use of firearms for suicide is quite common. The infliction of multiple self-inflicted wounds, including a fatal one, is rare among suicides, but it is possible and requires careful investigation. Aim To provide a forensic assessment of the possibility of suicide by multiple gunshot wounds. Methods. Archival material from the Kyiv City Clinical Bureau of Forensic Medicine and the Zhytomyr Regional Bureau of Forensic Medicine (2 "medical examination reports") was used. The objects of the study were: gunshot wounds on the head (wounds, wound channels), elastic bullets up to 9 mm cartridges and 9 mm bullets for pistol "Makarov", shot products, pistol "Makarov-MP 79" converted to shoot elastic bullets. Their characteristics were examined visually and under the stereo microscope. The detection of shot soot layers on skin flaps and gunsmith's grease was carried out in infrared and ultraviolet rays. The study of the elemental composition of shot products in objects of biological and non-biological origin was carried out using the X-ray fluorescence spectrometer "M4 TORNADO". Standard methods of variational statistics were used in the study. Results. The forensic examination of the entry and exit wounds and wounds on the head of the corpses of persons who died as a result of self-inflicted gunshot wounds, as well as of the bullets and weapons that caused bodily injuries, confirmed the possibility of committing suicide by firing double shots from pistols to shoot bullets of the so-called "non-lethal type": elastic bullets up to 9 mm cartridges and 9 mm bullets for pistol "Makarov". It was established that in case No 1 the first injury was non-fatal and the second was fatal, accompanied by damage to the skull and brain. In case No. 2, the first wound was fatal and the second was non-fatal, as it damaged only the soft tissues of the head without damaging the bones of the skull and brain. The wounds were caused by automatic shots due to the poor technical condition of the weapon, i.e. partial damage and wear of the trigger mechanism and the pistol sear. This was facilitated by a one-time partial self-destruction of the weapon, followed by the wedging of the next cartridge with an elastic bullet in the lower part of the barrel. Conclusion. Thus, the cases of double head injuries caused by shots from firearms (pistols) for shooting bullets of the so-called "non-lethal type" (elastic bullets up to 9 mm cartridges and 9 mm bullets for pistol "Makarov") serve as evidence of suicide. In case No. 1, one of the wounds was not fatal, as the wound channel began with an entrance hole in the lower half of the right temporal region, continued on the right through the right mastoid process and the soft tissues of the neck, and ended in the middle with an exit wound in the back of the neck. This wound was the first inflicted. The second wound was final and fatal, as there was damage to the skull and brain, as evidenced by the wound channel which passed through the right temporal cyst, the brain and its membranes, the left occipital bone, and ended with the exit wound in the left occipital region. It was the second in order of entry. In case 2, the first wound was fatal, resulting in damage to the bones of the skull and brain and the presence of an elastic ball in the substance of the brain. The second wound was non-fatal and tangential, injuring only the soft tissues of the head without damaging the bones of the skull and brain. It occurred as a result of automatic (independent) shots due to the poor technical condition of the weapon, namely partial damage and wear of the trigger mechanism and the pistol sear. This was facilitated by a one-time partial self-destruction of the weapon, followed by the wedging of the next cartridge with an elastic bullet in the lower part of the barrel.

Colour range of euglenoid (Euglenophyceae) blooms

The presence of autotrophs, heterotrophs and mixotrophs among euglenoid taxa, multiple means of nutrition, and high tolerance to a wide range of thermal living conditions contribute to their colonization of various types of water bodies in different climatic zones. The formation of water “blooms” by euglenoids occurs during accelerated development and intensive cell division of these organisms. Euglenoids outcompete other microalgae and produce significant biomass under favorable conditions. The ability to produce temporal, reproductive and protective cysts also contributes to rapid bloom formations. Our observations suggest that their features probably make them model organisms for observing environmental changes in small water bodies. So far, little attention has been given to the species-dependent color variation of euglenoid blooms. Long-time research on euglenoid taxonomy, biogeography and habitat observations allow observers to recognize different blooms depending on the species causing the phenomenon: Euglena sanguinea, E. mutabilis, E. clara, E. hemichromata, E. geniculata, E. agilis, Euglenaria anabaena, Euglenaformis chlorophoenica, Monomorphina pyrum, Phacus pleuronectes, Ph. orbicularis, Lepocinclis ovum, Trachelomonas volvocina, T. volvocinopsis and T. caudata. The color range of euglenoid blooms are presented here for the first time.

Growing Pains: A Rare Case of a Temporal Dermoid Cyst in an Adult and Review of the Literature

Dermoid cysts are common cutaneous developmental anomalies that occur due to the entrapment of ectodermal elements during embryonic closure. While the exact origin of dermoid cysts is unknown, they are theorized to originate from multipotent embryonic stem cells or translocated epithelial cells. Dermoid cysts are typically congenital but are sometimes diagnosed later in childhood and rarely in adulthood. They are reported as the most common pediatric skull tumors. Surgical excision is recommended to prevent enlargement, invasion, rupture, or infection. Temporal dermoid cysts, specifically, are extremely rare, with only a few cases having been reported in adulthood. We present a case of a 51-year old female with an enlarging left temporal mass found to be a dermoid cyst. The mass was excised, resulting in complete resolution of symptoms. This case highlights the importance of early excision, radiologic studies, and a tailored management approach based on cyst location. Our proposed treatment algorithm provides guidance for clinicians in identification and management of adult dermoid cysts.

20 Congenital Left Temporal Lobe Cyst: A Case Study of rs-fMRI and Cognitive Performance

Objective:Behavior is the product of interconnected brain regions that work together as networks. This case study examines whether there are differences between a participant with a large congenital left temporal lobe cyst, which impacted the volume of structures in the region, and control subjects of similar age on cognitive tasks and network connectivity as measured by resting-state functional magnetic resonance imaging (rs-fMRI).Participants and Methods:The case participant (CP; 71 year old female) and controls (CON; n = 25; 48% female) were recruited as part of a larger aging study. CON were chosen from the larger study population by age (+/- 10 years from CP; Range = 68-86 years). Cognitive tasks included: Shopping list memory task, Montreal Cognitive Assessment, WAIS-IV subtests: Digit Span, Digit-Symbol, Symbol Span, and Letter-Number Sequencing. For rs-fMRI, we administered four blood-oxygen level dependent (BOLD) functional connectivity (rs-fMRI) scans at 6 minutes each. Image processing was conducted using the CONN toolbox. Independent sample t-tests evaluated differences between CP and CON. Segregation was evaluated in the Auditory (Au), Cerebellar-basal ganglia (CBBG), Cingulo-Opercular Task Control (COTC), Dorsal Attention (DA), Default Mode (DMN), Fronto-Parietal Task Control (FPTC), Salience (Sa), Sensory Somatomotor Hand (SSH), Sensory Somatomotor Mouth (SSM), Visual (Vi), and Ventral Attention (VA) networks to assess CP’s functional segregation by network throughout the brain. Bonferroni correction was applied to account for multiple comparisons in cognitive testing (.05/7 for significance at p < 0.007) and network segregation (.05/11 for significance at p < .005).Results:Independent samples t-tests did not reveal significant differences across cognitive tasks (t(24) <1.04, p > .05). Network segregation did not reveal significant differences between CP and CON across networks examined (t(24) < 1.269, p > .005). However, DMN and DA segregation trended toward significance (t(24) = -2.724, p = .006 and t(24) =-2.006, p = .028), respectively) with CP demonstrating lower segregation as compared to CON.Conclusions:CP performed similarly on cognitive testing to CON, indicating that the congenital presence of a large temporal lobe cyst did not impact global cognition, list learning and memory, working memory, or processing speed. CP did not demonstrate significantly different segregation across networks of interest after Bonferroni correction. Our cognitive performance results are consistent with a similar case-study examining language, which revealed intact linguistic abilities (Tuckete et al., 2022). The lack of differences in cognitive performance and segregation highlight the capacity for plasticity in the human brain, even in the presence of a large structural abnormality. This also suggests that the processes of aging in this case are not markedly different from controls. In future research we intend to expand on this case study by evaluating right temporal to hippocampal seeds and language network seeds to delve deeper into memory and language functioning.

Giant Trichilemmal Cysts Mimicking an ox Horn associated with an Occipital Lipoma: An Observation at the Dermatology Hospital of Bamako

Summary: The pilar cyst or trichilemmal is a benign tumour of the skin appendages. This tumour develops on the isthmic part of the pilar follicle and is characterised histologically by trichilemmal keratinisation. We report a case of bilateral giant temporal trichilemmal cysts with a giant occipital lipoma. Observation: This is a 53-year-old patient who presented with multiple scalp lesions that had been present for three years. On clinical examination, there were two bilateral symmetrical temporal tumours with an occipital mass. Histology revealed a trichellemmal cyst for the temporal and a lipoma for the occipital.

Malignant transformation of a cerebral dermoid cyst into a squamous cell carcinoma with malignant intraperitoneal spreading along a ventriculoperitoneal shunt: illustrative case.

BACKGROUNDMalignant progression of intracranial dermoid cysts into squamous cell carcinoma is extremely rare with only three reports published so far. Intracranial dermoid cysts are uncommon benign tumors lined by stratified squamous epithelium of embryonic ectodermal origin.OBSERVATIONSHere, the authors present the case of a 64-year-old female with a recurrent temporal dermoid cyst. After surgery for the recurrent dermoid cyst, once in the early 1990s and another 16 years later, the patient presented with headache and nausea due to hydrocephalus. After implantation of a ventriculoperitoneal shunt, she deteriorated rapidly and died only 60 days after admission. Autopsy revealed malignant transformation of the epithelial lining of the dermoid cyst into a squamous cell carcinoma resulting in neoplastic meningiosis and intraperitoneal tumor spread along a previously implanted ventriculoperitoneal shunt.LESSONSMalignant transformation should be considered in patients with dermoid cyst who show new leptomeningeal contrast enhancement. In the case of hydrocephalus, alternatives to peritoneal shunting should be considered.

Aneurysmal bone cyst of the temporal bone presenting with reversible vestibular impairment.

Aneurysmal bone cysts are expansile benign lesions associated with compressive destruction and obscure pathogenesis. The most common sites of temporal bone involvement are the petrous apex, squamous portions and mastoid. This paper reports a right temporal aneurysmal bone cyst in a 51-year-old man who presented clinically with facial palsy, and hearing loss and impaired vestibular function. Magnetic resonance imaging and computed tomography findings were consistent with a diagnosis of aneurysmal bone cyst. Inter-operative findings showed that the lesion had caused compressive damage to the internal auditory canal. Following surgical excision, the patient experienced vertigo, indicating recovery of vestibular function. Follow-up imaging revealed complete resection without clinical recurrence. To our knowledge, this is the first report of aneurysmal bone cyst invasion of the inner auditory canal. Our clinical experience indicates that vestibular nerve damage recovery is relatively uncommon. This case report will hopefully inform future studies.

Temporosylvian arachnoid cysts in children. Part 1: Cognitive profile of children with a temporal cyst and impact of the cyst in daily life. A prospective study in 100 consecutive children.

The aim of this study was to determine the cognitive profile of children with a temporal arachnoid cyst (TAC) and its impact on daily life. The authors prospectively analyzed the cognitive and psychological profiles of 100 consecutive children relative to age and cyst characteristics (side, cyst size, and cyst shape: convex or nonconvex) and their outcome 4 years later. Mean IQs were normal but with high heterogeneity on Full Scale IQ (FSIQ; range 59-150); 29% of children had at least one Wechsler index below the norm, in particular, Processing Speed and Working Memory Indexes. Impairments were observed in language for 31% of children, as well as in verbal memory (28%), visual memory (23%), executive function (21%), and visual attention (24%). Half of the children (50%) needed rehabilitation for learning difficulties, and 26% had academic difficulties. The parental questionnaire BRIEF (Behavior Rating Inventory of Executive Function) revealed significant executive dysfunctions in daily life for 22% of the children. One-third of the patients (34%) required psychotherapy for anxiety or social disorders, with higher rates in patients with a right-sided cyst and older children. Cyst size had very little neuropsychological impact. Convex cysts were significantly associated with worse performance than nonconvex cysts on all Wechsler indexes and FSIQ, and in language, verbal memory, attention, and visuospatial skills. Children with a convex cyst had significantly more executive and behavior difficulties in daily life and more psychotherapy than other children. The effect of cyst shape was independent of Galassi type and cyst side. Children with a ruptured cyst or an incidentally discovered cyst usually had a good cognitive level. Four years later, children without initial disorders remained stable, whereas those with difficulties who did not undergo surgery needed more rehabilitation and school adaptations. This large cohort study revealed a varied profile of children with a TAC: at initial assessment, 50% had neuropsychological difficulties and needed rehabilitation and/or psychotherapy for learning or behavior difficulties, and 50% had no difficulties, which may explain the debate about this pathology. Patients with neuropsychological difficulties had a heterogeneous profile with normal intelligence but selective cognitive and/or behavior disorders that may have a long-term impact on their quality of life, particularly those with a right-sided cyst. A neuropsychological evaluation is not always necessary for a cyst discovered incidentally, but early evaluation is essential in patients with academic, learning, or psychological disorders. When assessment shows selective disorders presumably linked to cyst location, surgery may be considered, particularly for convex cysts, as this study revealed more effects in association with cyst shape than with cyst size and significantly poorer performance with a convex cyst.

Anatomical and diffusion-weighted imaging of brain abnormalities in third-trimester fetuses with cytomegalovirus infection.

In this study of cytomegalovirus (CMV)-infected fetuses with first-trimester seroconversion, we aimed to evaluate the detection of brain abnormalities using magnetic resonance imaging (MRI) and neurosonography (NSG) in the third trimester, and compare the grading systems of the two modalities. We also evaluated the feasibility of routine use of diffusion-weighted imaging (DWI) fetal MRI and compared the regional apparent diffusion coefficient (ADC) values between CMV-infected fetuses and presumed normal, non-infected fetuses in the third trimester. This was a retrospective review of MRI and NSG scans in fetuses with confirmed first-trimester CMV infection performed between September 2015 and August 2019. Brain abnormalities were recorded and graded using fetal MRI and NSG grading systems to compare the two modalities. To investigate feasibility of DWI, a four-point rating scale (poor, suboptimal, good, excellent) was applied to assess the quality of the images. Quantitative assessment was performed by placing a freehand drawn region of interest in the white matter of the frontal, parietal, temporal and occipital lobes and the basal ganglia, pons and cerebellum to calculate ADC values. Regional ADC measurements were obtained similarly in a control group of fetuses with negative maternal CMV serology in the first trimester, normal brain findings on fetal MRI and normal genetic testing. Fifty-three MRI examinations of 46 fetuses with confirmed first-trimester CMV infection were included. NSG detected 24 of 27 temporal cysts seen on MRI scans, with a sensitivity of 78% and an accuracy of 83%. NSG did not detect abnormal gyration visible on two (4%) MRI scans. Periventricular calcifications were detected on two MRI scans compared with 10 NSG scans. While lenticulostriate vasculopathy was detected on 11 (21%) NSG scans, no fetus demonstrated this finding on MRI. MRI grading correlated significantly with NSG grading of brain abnormalities (P < 0.0001). Eight (15%) of the DWI scans in the CMV cohort were excluded from further analysis because of insufficient quality. The ADC values of CMV-infected fetuses were significantly increased in the frontal (both sides, P < 0.0001), temporal (both sides, P < 0.0001), parietal (left side, P = 0.0378 and right side, P = 0.0014) and occipital (left side, P = 0.0002 and right side, P < 0.0001) lobes and decreased in the pons (P = 0.0085) when compared with non-infected fetuses. The ADC values in the basal ganglia and the cerebellum were not significantly different in CMV-infected fetuses compared with normal controls (all P > 0.05). Temporal and frontal ADC values were higher in CMV-infected fetuses with more severe brain abnormalities compared to fetuses with mild abnormalities. Ultrasound and MRI are complementary during the third trimester in the assessment of brain abnormalities in CMV-infected fetuses, with a significant correlation between the grading systems of the two modalities. On DWI in the third trimester, the ADC values in several brain regions are abnormal in CMV-infected fetuses compared with normal controls. Furthermore, they seem to correlate in the temporal area and, to a lesser extent, frontal area with the severity of brain abnormalities associated with CMV infection. Larger prospective studies are needed for further investigation of the microscopic nature of diffusion abnormalities and correlation of different imaging findings with postnatal outcome. © 2022 International Society of Ultrasound in Obstetrics and Gynecology.

Suprasellar arachnoid cyst with temporal extension or temporal cyst with suprasellar extension?

A 4-year-old female child presented to an emergency hospital with headache and episodes of seizures. Computed tomography and magnetic resonance imaging of the skull (Figs. 1a, b and c) were performed; they showed large suprasellar cystic lesions with right temporal extension and mild hydrocephalus. Subsequently, an endoscopic ventriculocystocysternotomy was performed (Figs. 1d, e, and f), which showed good results. Suprasellar arachnoid cysts account for 9%–21% of the pediatric arachnoid cysts [1,2]. According to the morphology and characteristics, there are three types of suprasellar arachnoid cysts, as follows: 1. Diencephalic leaflet dilatation of the Liliequist membrane with the formation of purely suprasellar cysts, which presents with hydrocephalus; 2. The defect of the mesencephalic leaflet of the Liliequist membrane with dilatation of the interpeduncular cistern, which presents without hydrocephalus; 3. Asymmetrical form that extends to other subarachnoid spaces, which presents with macrocrania and mild or no hydrocephalus [1], similar to the present case. The expansion could be due to an osmotic gradient, a slit valve mechanism, tissue debris transudation from the choroid plexus, or ectopic glial cells [3]. The first treatment option for suprasellar arachnoid cysts should be endoscopic ventriculocystocysternotomy; ventriculoperitoneal shunt may be considered the second treatment option if endoscopic ventriculocystocysternotomy fails [2]. Figure Caption Magnetic resonance imaging of the brain: (a) T1 axial and (b) T2 axial showing a large suprasellar (black arrows) cyst with expansion to the right temporal pole, having a mass effect and mild ventricular dilatation(white arrows) without ependymal transudation; (c) Sagittal FIESTA-T2 with compressive effect on the brain stem(white arrow) and basilar artery(black arrow) displacement; Endoscopic view: (d) ventriculocystotomy; (e) the third ventricular floor with pituitary stalk(black arrow) and gland(white arrow), dorsum of the sella turcica(black curved arrow), posterior communicating artery(black arrowhead), and oculomotor nerve(white arrowhead); (f) cyststocisternotomy was conducted with visualization of the basilar artery((black arrow) and dorsum of the saddle.

Right temporal intradiploic epi-dermoid cyst: a case report and review of the literature

&lt;p&gt;顱骨內表皮囊腫是一種少見、生長緩慢的良性腫瘤，可能是先天性或是後天造成的，多數表皮囊腫位於硬腦膜內，少數長在顱骨之中。這些病灶通常以無疼痛、數年至數十年間緩慢增大的腫塊來表現。我們報告一個年輕女性患有右側顳骨內表皮囊腫接受完整手術療程的病例，並且整理相關文獻探討。&lt;/p&gt; &lt;p&gt;&amp;nbsp;&lt;/p&gt;&lt;p&gt;Intradiploic epidermoid cysts are uncommon, slow-growing, benign tumors, ac-counting for approximately 1% of intracranial tumors. They can be congenital or ac-quired; most of them are located intradurally and rarely in the scalp. These lesions usually manifest as painless, gradually enlarging masses over years or decades. They are clinically and radiographically difficult to differentiate from other calvarial lesions. Accurate radiological assessment and complete surgical excision of the lesion and its capsule play a crucial role in ensuring favorable long-term outcomes. We present a case of a young female diagnosed with an epidermoid cyst in the right temporal bone who underwent complete and successful surgical treatment. A complete imaging study was obtained including X-rays and computed tomography and magnetic resonance imaging scans, which demonstrated pathognomonic findings of an epidermoid cyst. We review the relevant literature, pathogenesis, radiographic characteristics, and di-agnosis of the epidermoid cysts.&lt;/p&gt; &lt;p&gt;&amp;nbsp;&lt;/p&gt;

Pre- and postnatal brain magnetic resonance imaging in congenital cytomegalovirus infection: a case report and a review of the literature

BackgroundCongenital cytomegalovirus infection (cCMV) is the most common known viral cause of neurodevelopmental delay in children. The risk of severe cerebral abnormalities and neurological sequelae is greatest when the infection occurs during the first trimester of pregnancy. Pre- and postnatal imaging can provide additional information and may help in the prediction of early neurological outcome.Case presentationThis report presents the case of a newborn with cCMV infection with diffuse parenchymal calcifications, white matter (WM) abnormalities and cerebellar hypoplasia on postnatal brain imaging after magnetic resonance imaging (MRI) and neurosonogram (NSG) at 30 weeks showing lenticulostriate vasculopathy, bilateral temporal cysts and normal gyration pattern according to the gestational age (GA). No calcifications were seen on prenatal imaging.ConclusioncCMV infection can still evolve into severe brain damage after 30 weeks of GA. For this reason, a two-weekly follow-up by fetal NSG with a repeat in utero MRI (iuMRI) in the late third trimester is recommended in cases with signs of active infection.

Clinicoradiologic Correlation in 22 Egyptian Children With Megalencephalic Leukoencephalopathy With Subcortical Cysts.

Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare genetic form of cerebral white matter disease whose clinicoradiologic correlation has not been completely understood. In this study, we investigated the association between clinical and brain magnetic resonance imaging (MRI) features in 22 Egyptian children (median age 7 years) with MLC. Gross motor function was assessed using the Gross Motor Function Classification System, and evaluation of brain MRI followed a consistent scoring system. Each parameter of extensive cerebral white matter T2 hyperintensity, moderate-to-severe wide ventricle/enlarged subarachnoid space, and greater than 2 temporal subcortical cysts was significantly associated (P < .05) with worse Gross Motor Function Classification System score, language abnormality, and ataxia. Having >2 parietal subcortical cysts was significantly related to a worse Gross Motor Function Classification System score (P = .04). The current study indicates that patients with MLC manifest signification association between certain brain MRI abnormalities and neurologic features, but this should be confirmed in larger studies.

Hepatosplenomegaly and Periventricular Cyst in a Neonate with Direct Hyperbilirubinemia

Hepatosplenomegaly and Periventricular Cyst in a Neonate with Direct Hyperbilirubinemia

A Rare Case of Temporal Scalp Dermoid Cyst with No Intracranial Extension

We report a case of 37-year-old female patient presented with a history of a scalp swelling since birth. The swelling increased in size progressively. Magnetic resonance imaging of the brain revealed extracranial cystic lesion over the temporal bone with no intracranial extension. Cyst was excised completely with no postoperative complications. On histopathology it was dermoid cyst.

Intracranial Epidermoid Cyst: A Rare Case Series of 3 Patients

Of the intracranial epidermoids, temporal pole, interhemispheric region and prepontine, premedullary and inter-peduncular cisterns epidermoid are rare and only few cases have been reported. This is a case series study of 3 patients with temporal pole, interhemispheric region and in prepontine, premedullary and inter-peduncular cisterns epidermoids surgically treated in our institution. The age at the time of presentation varied between 40 and 65 years and 2 were males and one female. The presenting feature was headache, giddiness and visual disturbances. On computerized tomography scan the lesions showed dense calcification. On magnetic resonance imaging, the lesions were located in the temporal pole, interhemispheric region and in prepontine, premedullary and inter-peduncular cisterns with heterogenous signal intensities. All 3 patients underwent surgical resection. Keywords: Temporal pole epidermoid cyst, Interhemispheric epidermoid cyst, Prepontine epidermoid cyst, Intracranial Epidermoid Cyst

Non-Ruptured Temporal Lobe Dermoid Cyst Concomitant with Focal Cortical Dysplasia Causing Temporal Lobe Epilepsy—A Case Report and Literature Review

Background: Intracranial dermoid cyst is a rare, benign, nonneoplastic tumor-like lesion that could cause seizures, headache, and hydrocephalus. We hypothesized that the temporal lobe dermoid cyst in combination with other factors were causing the epileptic seizure. Methods: We encountered a 17-year-old girl with anti-seizure medication-resistant epilepsy secondary to dermoid cyst located in the temporal region depicted on magnetic resonance imaging (MRI). She showed neither symptoms of meningitis nor rupture of the cyst according to serial MRI. We hypothesized that temporal lobe dermoid cyst in combination with other factors, such as focal cortical dysplasia (FCD), etc., was causing epileptic seizures in this case. She underwent dermoid cyst removal surgery with resection of the tip of the antero-inferior temporal lobe. Results: Histopathological study showed multiple small intramedullary dermoid cysts in the left antero-inferior temporal lobe in addition to MRI lesions and FCD. Conclusion: A patient with medically intractable epilepsy secondary to left temporal lobe dermoid cyst showed multiple intramedullary dermoid cysts and focal cortical dysplasia that might have interacted to create epileptogenicity. To our knowledge, this is the first case report of dermoid cyst concomitant with FCD.