Two arc welders with more than 25 years of welding of tanks and pipelines showed ordinary subjective symptoms such as asthenia, dizziness, headaches, lumbalgia, profuse sweating, as well as disturbances in walking with feeling of spasticity in the calves in one of them, while the other one showed slight cerebellar signs (dysmetry, retropulsion at Romberg's test). The dosages in the air inhaled by the welders presented high concentrations of manganese up to 125 mgr/m3. In the feces of their workmates was found 2,5 times more Mn than is found in normal subjects. Only a thorough study of the electric neuro-muscular excitability (curves intensity/duration) and of electromyography allowed to prove in the two patients peripheral nervous lesions i.e. partial denervation. These disturbances in the electric neuro-muscular excitability seem to appear earlier than the usual clinical signs of manganese intoxication.
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