Synthesis Of Dihydrobenzo Research Articles

Lewis Acid Mediated Domino Intramolecular Cyclization: Synthesis of Dihydrobenzo[a]fluorenes.

An efficient and facile method for the regioselective synthesis of novel dihydrobenzo[a]fluorenes from readily accessible alkynols is presented. The current strategy triggers the formation of a dual C-C bond intramolecularly via Lewis acid catalysis under mild reaction conditions. Notably, secondary as well as tertiary alcohols bearing an alkyne moiety have been smoothly transformed into the corresponding products. As a result, novel tetracyclic dihydrobenzo[a]fluorenes have been accomplished using this approach.

Synthesis of Dihydrobenzo[1,4]oxazines by Palladium-Catalyzed Cyclization of N-Substituted 2-Aminophenols with Propargylic Carbonates

Synthesis of Dihydrobenzo[1,4]oxazines by Palladium-Catalyzed Cyclization of N-Substituted 2-Aminophenols with Propargylic Carbonates

A Simple One‐pot Three‐component Synthesis of Dihydrobenzo[4,5]imidazo[2,1‐ b ]thiazol‐3‐ols by Reaction of Acyl Chlorides, Isocyanides, and 2‐Mercaptobenzimidazoles

A Simple One‐pot Three‐component Synthesis of Dihydrobenzo[4,5]imidazo[2,1‐ <i>b</i> ]thiazol‐3‐ols by Reaction of Acyl Chlorides, Isocyanides, and 2‐Mercaptobenzimidazoles

ChemInform Abstract: Synthesis of Dihydrobenzo[b]pyrimido[4,5‐e][1,4]thiazepines; Derivatives of a Novel Ring System.

Several derivatives of the novel dihydrobenzo[b]pyrimido[4,5-e][1,4]thiazepine ring system have been synthesised through the initial heterocyclisation of 2,4-dichloro-5-(chloromethyl)-6-methylpyrim...

Synthesis of Dihydrobenzo[b]pyrimido[4,5-e][1,4]Thiazepines; Derivatives of a Novel Ring System

Several derivatives of the novel dihydrobenzo[b]pyrimido[4,5-e][1,4]thiazepine ring system have been synthesised through the initial heterocyclisation of 2,4-dichloro-5-(chloromethyl)-6-methylpyrimidine with o-aminothiophenol followed by treatment with various secondary amines in boiling ethanol.

ChemInform Abstract: Synthesis of Dihydrobenzo[b]furans by Diastereoselective Acyloxyarylation.

AbstractA highly regio‐ and diastereoselective dearomatizing 2,3‐difunctionalization of benzofurans (I) is reported.

Synthesis of Dihydrobenzo[h]coumarins and Their 4‐Methyl Analogues.

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Synthesis of Dihydrobenzo[h]coumarins and Their 4‐Methyl Analogs

Dihydrobenzo[h]coumarins (5a–7a) and their 4‐methyl analogs (5b–7b) were synthesized from 1‐naphthol via two different synthetic routes. One pathway is the direct condensation of 5,8‐dihydro‐1‐naphthol (9) with malic acid or ethyl acetoacetate, affording 7,10‐dihydrobenzo[h]coumarins 7a and 7b, respectively. The other is through the oxidation of 7,8,9,10‐tetrahydrobenzo[h] coumarins (15a–b), followed by the reduction of the carbonyl group and dehydration of hydroxyl group, giving 7,8-dihydrobenzo[h]coumarins (5a, b) and 9,10-dihydrobenzo[h]coumarins (6a, b). The regio selectivities for the oxidation reactions of 15a, b were rationalized on the basis of quantum chemical calculations and further confirmed by the X‐ray crystallographic analysis of the derivatives of oxidation products.