Synergistic Modulation Research Articles

Synergistic Modulation at Atomically Dispersed Fe/Au Interface for Selective CO2 Electroreduction

The electrocatalytic carbon dioxide reduction reaction (CO2RR) offers an attractive route to fuels and feedstocks from renewable energy. Gold is active for the electrochemical CO2RR to CO, while the competing hydrogen evolution reaction is unavoidable. Here, we report a synergistic strategy, via introducing atomically dispersed Fe to tune the electronic structure of the Au nanoparticle, to improve the CO selectivity. By using operando X-ray absorption and infrared spectroscopies, we reveal the dynamic structural evolution and the adsorption of reactant intermediates at the single-atom Fe1/Au interface. During the reaction, the interaction between Fe and Au atoms becomes stronger, and the Fe1/Au synergies affect the adsorption of reaction intermediates, thus improving the selectivity of CO up to 96.3% with a mass activity of 399 mA mg-1. These results highlight the significant importance of synergistic modulation for advancing the single-atom decorated nanoparticle catalysis.

Al, Fe-codoped CoP nanoparticles anchored on reduced graphene oxide as bifunctional catalysts to enhance overall water splitting

Rational design of high-efficiency and low-cost catalysts for water splitting electrolysis plays an important role in clean energy conversion technology. Herein, density functional theory simulations indicate that the codoping of p-metal Al and d-metal Fe could reasonably regulate the electronic structure of CoP, resulting in an optimal H adsorption free energy. Based on this finding, we successfully prepared a bifunctional catalyst of Al, Fe-codoped CoP nanoparticles/reduced graphene oxide, which displays superior HER performance in a wide pH range and OER performance in the alkaline medium with high H2/O2 evolution rates and Faradaic efficiencies. For overall water splitting, such a catalyst exhibits excellent activity (a low cell voltage of 1.66 V at 10 mA cm−2) and durability. The strategy of synergistic modulation of electronic structure by introducing different-type dopants into a hybrid proposed in this work is beneficial for designing novel electrocatalysts for applications in energy-conversion devices.

A FN-MdV pathway and its role in cerebellar multimodular control of sensorimotor behavior

The cerebellum is crucial for various associative sensorimotor behaviors. Delay eyeblink conditioning (DEC) depends on the simplex lobule-interposed nucleus (IN) pathway, yet it is unclear how other cerebellar modules cooperate during this task. Here, we demonstrate the contribution of the vermis-fastigial nucleus (FN) pathway in controlling DEC. We found that task-related modulations in vermal Purkinje cells and FN neurons predict conditioned responses (CRs). Coactivation of the FN and the IN allows for the generation of proper motor commands for CRs, but only FN output fine-tunes unconditioned responses. The vermis-FN pathway launches its signal via the contralateral ventral medullary reticular nucleus, which converges with the command from the simplex-IN pathway onto facial motor neurons. We propose that the IN pathway specifically drives CRs, whereas the FN pathway modulates the amplitudes of eyelid closure during DEC. Thus, associative sensorimotor task optimization requires synergistic modulation of different olivocerebellar modules each provide unique contributions.

Neuromodulatory Interventions for Traumatic Brain Injury.

Neuromodulatory Interventions for Traumatic Brain Injury.

Synergetic Subnano Ni‐ and Mn‐Oxo Clusters Anchored by Chitosan Oligomers on 2D g‐C3N4 Boost Photocatalytic CO2 Reduction

Synergistic modulation of photogenerated electrons and holes of g‐C3N4 especially achieved by simply modifying bimetallic species is highly desired for efficient photocatalytic CO2 reduction. Herein, ultrasmall subnano Ni‐ and Mn‐oxo clusters (average diameter of ≈0.8 nm) are uniformly anchored on tailored chitosan oligomer (COS)‐functionalized ultrathin g‐C3N4 nanosheets via OH and NH2 in COS as the coordination sites. Optimized Ni and Mn comodified photocatalyst obtained by regulating bimetallic molar ratio exceptionally exhibits 22‐times CO2 conversion rate under solar‐light irradiation and ≈20‐times quantum efficiency at 405 nm light compared with pristine g‐C3N4. By electron paramagnetic resonance, surface photovoltage spectroscopy, fluorescence spectra, photoluminescence spectra, and electrochemical curves, it is evidenced the enhanced photoactivities originate from the synergetic effect between Ni‐ and Mn‐oxo species, capable of photoelectron‐capture along with catalytic CO2 activation and hole‐capture along with catalytic H2O activation, respectively. More importantly, due to the carrier‐modulating capability difference, it is verified only a matching Ni:Mn molar ratio leads to the best charge separation then photoactivity as supported by the transient‐state photoluminescence spectra. A new avenue to rationally modulate photogenerated charge carriers for fabricating efficient g‐C3N4‐based photocatalysts for solar‐fuel production is proposed.

Synergistic modulation of electrical and thermal properties of Cu1.8S bulk materials via nanostructuring and band engineering

Digenite (Cu1.8S) is a subject of increasing interest as a potential p-type thermoelectric material because of its element abundance, low cost and environmental friendliness. However, its thermoelectric properties are limited by high thermal conductivity. In this work, the Cu1.8S with x wt% Bi2Te3 (x = 0, 0.5, 1, 3, 5) samples were prepared by combining mechanical alloying (MA) and spark plasma sintering (SPS) technology. The results reveal that Bi2Te3 addition can effectively optimize the thermoelectric properties of Cu1.8S materials by tuning the carrier concentration and introducing nanoprecipitates. As a result, the optimal Cu1.8S +1 wt% Bi2Te3 sample presents an excellent performance, with relatively high ZT value of 1.1 (at 773 K), which is approximately 2.4 times that of pure Cu1.8S.

Dynamic Control of 4-Hydroxyisoleucine Biosynthesis by Modified l-Isoleucine Biosensor in Recombinant Corynebacterium glutamicum.

4-Hydroxyisoleucine (4-HIL), a promising drug for treating diabetes, can be synthesized from the self-produced l-isoleucine (Ile) by expressing the Ile dioxygenase gene ido in Corynebacterium glutamicum. However, the requirement of three substrates, Ile, α-ketoglutarate (α-KG), and O2, makes such de novo biosynthesis difficult to be fulfilled effectively under static engineering conditions. In this study, dynamic control of 4-HIL biosynthesis by the Ile biosensor Lrp-PbrnFE was researched. The native PbrnFE promoter of natural Ile biosensor was still weak even under Ile induction. Through tetA dual genetic selection, several modified stronger PbrnFEN promoters were obtained from the synthetic library of the Ile biosensor. Dynamic regulation of ido expression by modified Ile biosensors increased the 4-HIL titer from 24.7 mM to 28.9-74.4 mM. The best strain ST04 produced even a little more 4-HIL than the static strain SN02 overexpressing ido by the strong PtacM promoter (69.7 mM). Further dynamic modulation of α-KG supply in ST04 by expressing different PbrnFEN-controlled odhI decreased the 4-HIL production but increased the l-glutamate or Ile accumulation. However, synergistic modulation of α-KG supply and O2 supply in ST04 by different combinations of PbrnFEN-odhI and PbrnFEN-vgb improved the 4-HIL production significantly, and the highest titer (135.3 mM) was obtained in ST17 strain regulating all the three genes by PbrnFE7. This titer was higher than those of all the static metabolic engineered C. glutamicum strains ever constructed. Therefore, dynamic regulation by modified Ile biosensor is a predominant strategy for enhancing 4-HIL de novo biosynthesis in C. glutamicum.

Synergistic optimization of electrical and thermal transport in n-type Bi-doped PbTe by introducing coherent nanophase Cu1.75Te

Based on the calculated results of band structures and density of states, Bi doping is used to adjust its carrier concentration in order to obtain n-type PbTe materials with high power factor. Then, coherent nanophase Cu1.75Te is in situ formed in the n-type PbTe matrix, which can simultaneously optimize the thermal and electrical properties. As a result, at a relative lower temperature than other reports, the highest ZT value of 1.4 is obtained at 623 K for the nominal Pb0.995Bi0.005Te+0.86 wt% Cu1.75Te sample. More importantly, the ZT hold a higher value in the broad temperature; especially, ZT value is about 1.2–1.4 in the temperature range of 573–773 K, which is beneficial to the significant average ZT value ZTave ∼ 0.9 in the temperature range of 300–773 K. These results indicate that it is an effective and feasible method to enhance the thermoelectric properties via synergistic modulation of electrical and thermal transport properties by element doping and in situ coherent nanophase.

Palladium nanoparticles embedded PPy shell coated CNTs towards a high performance hydrazine detection through optical fiber plasmonic sensor

A facile in-situ solvothermal method has been proposed for the synthesis of palladium nanoparticles (PdNPs) embedded in polypyrrole (PPy) shell coated over carbon nanotubes (CNTs). The synergistic modulation of physicochemical properties of PdNPs/PPy@CNTs nanocomposite so prepared upon interaction with hydrazine has been explored for the surface plasmon resonance (SPR) based sensing on optical fiber substrate with silver as plasmonic material. The efficacy of the nanocomposite has been probed for 0-1500 nM hydrazine concentration range. The effects of the composition of nanocomposite, thickness of the sensing layer and the pH of the hydrazine solution have been studied to obtain the best sensing performance. The sensor possesses highest sensitivity of 0.09 nm/nM for lowest concentration of hydrazine with limit of detection (LOD) of 20 nM. The specificity of the probe has been tested by using several other interfering analytes. The proposed probe has been found to be feasible for the detection of hydrazine in ground water with high stability, accuracy and reproducibility. The proposed optical fiber probe could be very promising for the hypergolic fuels like hydrazine due to the facility of online remote monitoring for an early detection of any leakage in such combustible environments.

A Methionine Sulfoxide Reductase B Is Required for the Establishment of Astragalus sinicus-Mesorhizobium Symbiosis.

Methionine sulfoxide reductase B (MsrB) is involved in oxidative stress or defense responses in plants. However, little is known about its role in legume-rhizobium symbiosis. In this study, an MsrB gene was identified from Astragalus sinicus and its function in symbiosis was characterized. AsMsrB was induced under phosphorus starvation and displayed different expression patterns under symbiotic and nonsymbiotic conditions. Hydrogen peroxide or methyl viologen treatment enhanced the transcript level of AsMsrB in roots and nodules. Subcellular localization showed that AsMsrB was localized in the cytoplasm of onion epidermal cells and co-localized with rhizobia in nodules. Plants with AsMsrB-RNAi hairy roots exhibited significant decreases in nodule number, nodule nitrogenase activity and fresh weight of the aerial part, as well as an abnormal nodule and symbiosome development. Statistical analysis of infection events showed that plants with AsMsrB-RNAi hairy roots had significant decreases in the number of root hair curling events, infection threads and nodule primordia compared with the control. The content of hydrogen peroxide increased in AsMsrB-RNAi roots but decreased in AsMsrB overexpression roots at the early stage of infection. The transcriptome analysis showed synergistic modulations of the expression of genes involved in reactive oxygen species generation and scavenging, defense and pathogenesis and early nodulation. In addition, a candidate protein interacting with AsMsrB was identified and confirmed by bimolecular fluorescence complementation. Taken together, our results indicate that AsMsrB plays an essential role in nodule development and symbiotic nitrogen fixation by affecting the redox homeostasis in roots and nodules.

2D Transition Metal Dichalcogenides: Design, Modulation, and Challenges in Electrocatalysis.

Hydrogen has been deemed as an ideal substitute fuel to fossil energy because of its renewability and the highest energy density among all chemical fuels. One of the most economical, ecofriendly, and high-performance ways of hydrogen production is electrochemical water splitting. Recently, 2D transition metal dichalcogenides (also known as 2D TMDs) showed their utilization potentiality as cost-effective hydrogen evolution reaction (HER) catalysts in water electrolysis. Herein, recent representative research efforts and systematic progress made in 2D TMDs are reviewed, and future opportunities and challenges are discussed. Furthermore, general methods of synthesizing 2D TMDs materials are introduced in detail and the advantages and disadvantages for some specific methods are provided. This explanation includes several important regulation strategies of creating more active sites, heteroatoms doping, phase engineering, construction of heterostructures, and synergistic modulation which are capable of optimizing the electrical conductivity, exposure to the catalytic active sites, and reaction energy barrier of the electrode material to boost the HER kinetics. In the last section, the current obstacles and future chances for the development of 2D TMDs electrocatalysts are proposed to provide insight into and valuable guidelines for fabricating effective HER electrocatalysts.

Laser‐assisted topical steroid application versus steroid injection for treating keloids: A split side study

Approaches to improve keloid scars include intralesional corticosteroid injections and fractional lasers exclusively. The combinative use of ablative fractional laser therapy and occluded topical corticosteroid as a drug delivery method enhances therapeutic outcome of two efficient scar therapy modules into one simple synergistic module. To compare the therapeutic effect of combining two modalities of scar treatment, the first is fractional ablative laser treatment and the other is occluded topical corticosteroid to the standard use of intralesional steroid injection. Keloids from thirty suffering patients were split faced into two identical parts; one part received an intralesional corticosteroid injection while the other part was treated first with fractional ablative 2940nm Er: YAG laser followed by occluded topical application of steroid cream. Four treatment sessions were performed with 4-week interval between sessions. Every session was assessed photographically and using the Vancouver Scar Scale (VSS). The mean keloid VSS before treatment was 6.9±1.9. After treatment, the mean keloid VSS of the injection side became 2.63±2.09, and mean keloid VSS of the laser-treated side became 2.07±2.02. Each of the treated halves showed a statistically significant improvement in their VSS. However, no statistically significant differences were observed for either of the treated halves over the other one. Although intralesional steroids injection is the standard procedure for treatment of keloid scars, the use of ablative fractional laser-assisted delivery of topical steroid can offer a safer and a better aesthetic treatment option.

79-OR: Signal-Dependent Chromatin Accessibility Dynamics in Pancreatic Islet Dysfunction

In type 2 diabetes (T2D), inflammation induces massive changes in beta cell transcriptome and epigenome, resulting in eventual dysfunction and death of beta cells. Accordingly, strategies designed to protect beta cells from inflammatory stress at transcriptional and epigenetic level could be attractive for combating diabetes. Through genome-wide CRISPR screening in human stem cell differentiated islet like organoids, we identified a novel mechanism connecting signal- dependent transcription by vitamin D receptor (VDR) and fine-tuning of chromatin accessibility by a balance between two SWI/SNF complexes, BAF and PBAF. Our studies revealed that VDR recruits BAF and PBAF complexes through two bromodomain proteins, BRD9 and BRD7, respectively. The balance between BAF-BRD9 and PBAF-BRD7 determines the VDR-driven anti-inflammatory and pro-survival response in pancreatic beta cells. In a dual regulatory mechanism, inhibition of the VDR-BRD9 interaction in combination with ligand activation of VDR cooperate to dismiss the BAF-BRD9 complex and shift the balance to the activating PBAF-BRD7 complex to induce a coordinated transcriptional response. Notably, pharmacologically potentiated VDR signaling by a synthetic ligand in combination with a BRD9 inhibitor can partially restore beta cell function and glucose homeostasis in various T2D mouse models. Tissue specific models further confirmed the functional role of VDR and BRD9 in beta cell stress response in vivo. Together, our results revealed that an unexpected epigenetic balance between the bromodomain readers has a major impact on beta cell survival and glucose homeostasis, and demonstrated the therapeutic potential of targeting inflammatory/metabolic stress through synergistic modulation of hormone receptors and chromatin accessibility. Disclosure Z. Wei: None. Funding National Institutes of Health (1K01DK120808)

Synergistic Modulation of Non-Precious-Metal Electrocatalysts for Advanced Water Splitting.

ConspectusHydrogen is an ideal energy carrier and plays a critical role in the future energy transition. Distinct from steam reforming, electrochemical water splitting, especially powered by renewables, has been considered as a promising technique for scalable production of high-purity hydrogen with no carbon emission. Its commercialization relies on the reduction of electricity consumption and thus hydrogen cost, calling for highly efficient and cost-effective electrocatalysts with the capability of steadily working at high hydrogen output. This requires the electrocatalysts to feature (1) highly active intrinsic sites, (2) abundant accessible active sites, (3) effective electron and mass transfer, (4) high chemical and structural durability, and (5) low-cost and scalable synthesis. It should be noted that all these requirements should be fulfilled together for a practicable electrocatalyst. Much effort has been devoted to addressing one or a few aspects, especially improving the electrocatalytic activity by electronic modulation of active sites, while few reviews have focused on the synergistic modulation of these aspects together although it is essential for advanced electrochemical water splitting.In this Account, we will present recent innovative strategies with an emphasis on our solutions for synergistically modulating intrinsic active sites, electron transportation, mass transfer, and gas evolution, as well as mechanical and chemical durability, of non-precious-metal electrocatalysts, aiming for cost-effective and highly efficient water splitting. The following approaches for coupling these aspects are summarized for both cathodic hydrogen evolution reaction (HER) and anodic oxygen evolution reaction (OER). (1) Synergistic electronic modulations. The electronic structure of a catalytic site determines the adsorption/desorption of reactive intermediates and thus intrinsic activity. It can be tuned by heterogeneous doping, strain effect, spin polarization, etc. Coupling these effects to optimize the reaction pathways or target simultaneously the activity and stability would advance electrocatalytic performance. (2) Synergistic electronic and crystalline modulation. The crystallinity, crystalline phase, crystalline facets, crystalline defects, etc. affect both activity and stability. Coupling these effects with electronic modulation would enhance the activity together with stability. (3) Synergistic electronic and morphological modulation. It will focus on concurrently modulating electronic structure for improving the intrinsic activity and morphology for increasing accessible active sites, especially through single action or processing. The mass transfer and gas evolution properties can also be enhanced by morphological modulation to enable water splitting at large output. (4) Synergistic modulation of elementary reactions. Electrocatalytic reaction generally consists of a couple of elementary reactions. Each one may need a specific active site. Designing and combining various components targeting every elementary step on a space-limited catalyst surface will balance the intermediates and these steps for accelerating the overall reaction. (5) Integrated electrocatalyst design. Taking all these strategies together into account is necessary to integrate all above essential features into one electrocatalyst for enabling high-output water electrolysis. Beyond the progress made to date, the remaining challenges and opportunities is also discussed. With these insights, hopefully, this Account will shed light on the rational design of practical water-splitting electrocatalysts for the cost-effective and scalable production of hydrogen.

Cooperatively modulating reactive oxygen species generation and bacteria-photocatalyst contact over graphitic carbon nitride by polyethylenimine for rapid water disinfection

Graphitic carbon nitride (C3N4) has gained broad attention as a metal-free photocatalyst for water disinfection. However, the low photocatalytic bactericidal activity of pristine C3N4 limits its applications. Here, we report a facile method to boost the photocatalytic disinfection activity of C3N4 with polyethyleneimine (PEI). With PEI modification, the generation of long-lifespan reactive oxygen species (ROS,•O2− and H2O2) in photocatalysis is significantly improved. Additionally, scanning electron microscopy and the atomic force microscopy force spectroscopy characterization reveal that PEI promotes the bacteria-photocatalyst contact via electrostatic adhesion. Due to the synergistic modulation of ROS generation and bacteria-photocatalyst interaction, the photocatalytic bactericidal activity of C3N4 is dramatically enhanced after PEI modification. Notably PEI/C3N4 composite achieves 6.2 logs of inactivation efficiency for Escherichia coli within 45 min and 4.2 logs for Enterococcus faecalis within 60 min under simulated solar irradiation. Overall, this work provides insights on designing metal-free photocatalysts with judicious polymer for antibacterial applications.

Absorbable Thioether Grafted Hyaluronic Acid Nanofibrous Hydrogel for Synergistic Modulation of Inflammation Microenvironment to Accelerate Chronic Diabetic Wound Healing.

Current standard of care dressings are unsatisfactorily inefficacious for the treatment of chronic wounds. Chronic inflammation is the primary cause of the long-term incurable nature of chronic wounds. Herein, an absorbable nanofibrous hydrogel is developed for synergistic modulation of the inflammation microenvironment to accelerate chronic diabetic wound healing. The electrospun thioether grafted hyaluronic acid nanofibers (FHHA-S/Fe) are able to form a nanofibrous hydrogel in situ on the wound bed. This hydrogel degrades and is absorbed gradually within 3 days. The grafted thioethers on HHA can scavenge the reactive oxygen species quickly in the early inflammation phase to relieve the inflammation reactions. Additionally, the HHA itself is able to promote the transformation of the gathered M1 macrophages to the M2 phenotype, thus synergistically accelerating the wound healing phase transition from inflammation to proliferation and remodeling. On the chronic diabetic wound model, the average remaining wound area after FHHA-S/Fe treatment is much smaller than both that of FHHA/Fe without grafted thioethers and the control group, especially in the early wound healing stage. Therefore, this facile dressing strategy with intrinsic dual modulation mechanisms of the wound inflammation microenvironment may act as an effective and safe treatment strategy for chronic wound management.

3D Holey‐Graphene Architecture Expedites Ion Transport Kinetics to Push the OER Performance

AbstractThe kinetics process of heterogeneous catalysis involves several steps including adsorption, diffusion, and surface chemical reactions. Current studies generally aim at increasing active site amount and improving intrinsic activity. However, the ion diffusion kinetics at the electrode/electrolyte interface as a bottleneck has been rarely directly addressed. Here, a 3D holey‐graphene framework is demonstrated as a catalyst‐loading platform, with nanoscale holes that can be elaborately tuned via facile aqueous‐phase chemical etching. This enables the ions to be efficiently transported to deeply buried active sites to mitigate their insufficient supply. With systematical electrochemical investigations tuned by varied pore structures, a series of models from a simplified equivalent circuit to complicate realistic one are proposed to figure out the modulation rules of weakened electrochemical diffusion domination and identify the ion transport resistance as well. Moreover, given the inevitable negative effect on the conductivity of graphene skeleton by introducing nanoscale holes, the balance between the outside ion transport and the inside charge transport of electrode is highlighted. Such a protocol represents a synergistic modulation of catalytic performance from both the supply side (reactive ion transport) and the consuming side (active site), and provides striking information for the precise design of catalyst electrodes toward further pushing the oxygen evolution reaction performance limit.

Intrinsic Plasticity of Cerebellar Purkinje Cells Contributes to Motor Memory Consolidation.

Intrinsic plasticity of cerebellar Purkinje cells (PCs) has recently been demonstrated in cerebellar local circuits; however, its physiological impact on cerebellar learning and memory remains elusive. Here, we suggest that intrinsic plasticity of PCs is tightly involved in motor memory consolidation based on findings from PC-specific STIM1 knockout male mice, which show severe memory consolidation deficiency in vestibulo-ocular reflex memory. Gain-up training of the vestibulo-ocular reflex produced a decrease in the synaptic weight of PCs in both the WT and KO groups. However, intrinsic plasticity was impaired only in the knockout mice. Furthermore, the observed defects in the intrinsic plasticity of PCs led to the formation of aberrant neural plasticity in the vestibular nucleus neurons. Our results suggest that synergistic modulation of intrinsic and synaptic plasticity in PCs is required for the changes in downstream plasticity in the vestibular nucleus, and thereby contributing to the long-term storage of motor memory.SIGNIFICANCE STATEMENT Synaptic plasticity is a well-known mechanism for learning and memory. Although plasticity of excitability, intrinsic plasticity, of the cerebellar Purkinje cell has been reported in both directions (potentiation and depression), the physiological role of intrinsic plasticity still remains ambiguous. In this study, we suggest that both synaptic and intrinsic plasticity are required for successful memory consolidation in cerebellar eye movement learning. Despite successful induction and maintenance of synaptic plasticity, we found deficits of memory consolidation when there were defects in intrinsic plasticity. Our results suggest that intrinsic plasticity of cerebellar Purkinje cell has a significant role in motor memory consolidation.

Charge separation and interfacial selectivity induced by synergistic effect of ferroelectricity and piezoelectricity on PbTiO3 monocrystalline nanoplates

Abstract Charge separation and surface chemistry are essential for photocatalytic reaction, which is challenging to manipulate the performance of catalyst. In this work, the effects of ferroelectric and piezoelectricity (piezophototronics) properties on photocatalytic properties were studied in detail by using PbTiO3 monocrystalline nanoplates (PMNs). Visualization of charge distribution on the surface of PMNs was carried out by noble metal loading and selectivity dependence of crystal surface was revealed by choosing organic molecules with different charge properties. The apparent quantum efficiency (AQE) for photocatalytic water splitting can be promoted to 6.5 times by the ferroelectric/piezoelectricity synergistic modulation of the internal carriers and the interaction with the matrix. This strategy based on the coupling of ferroelectricity and piezoelectricity provides a new idea for the preparation of highly active photocatalysts and the improvement of photocatalytic performance.

Fabrication of structurally colored basso-relievo with modulated elliptical vibration texturing

Elliptical vibration texturing is a newly arising method for the fast and cost-effective generation of near-subwavelength micro-structures on metal surfaces. This study proposes a fabrication method for structurally colored basso-relievo by combining the surface sculpturing and elliptical vibration texturing in one-step machining. Synergistic modulations of both nominal cutting speed and depth-of-cut (DOC) in elliptical vibration texturing are applied to provide concave-convex topography and structural coloration. A new rendering strategy for the face turning configuration with an equidistant spiral tool path has been presented to improve the image rendering efficiency over the raster scan tool path. In addition, different from the conventional elliptical vibration texturing, the nominal DOC dynamically changes pixel by pixel in the proposed new process. In order to identify the effects of DOC and elliptical vibration trajectories on the surface quality and fidelity of generated gratings, grooving experiments have been conducted on brass samples to further the understanding of nonlinear tool-workpiece interactions. Finally, both raster scan and face turning tests have been performed on an ultraprecision platform with optimized process parameters. Structurally colored basso-relievos with high quality have been successfully demonstrated using the proposed fabrication method.