Supratrochlear Foramen Research Articles

CT findings and anatomical aspects of a Labrador retriver humerus characterized by osteophytosis of the sulcus intertubercularis and obliteration of the supratrochlear foramen.

Degenerative changes in the skeletal system of dogs may occur as a consequence of aging, trauma, infection, or inflammation. The object of this study consisted of an 8-year-old male Labrador dog that was brought to a private veterinary clinic after a road traffic accident and died despite all interventions. For a different study planned in our department, CT images were taken of the Labrador retriever's humerus and osteophytes to encounter incidentally were investigated for found in these images. After the CT scan, the dissected humerus bones were boiled to remove soft tissues. Subsequently, the bones were underwent with a 10% hydrogen peroxide solution for bleaching. Osteophytes in the proximal part of the humerus extended from the tuberculum majus and tuberculum minus towards the cranial direction, forming a complete ring-like structure at the level of the sulcus intertubercularis in the left humerus. Although not fully ring-shaped, similar osteophytes were found in the right humerus. In addition, it was observed that the foramen supratrochleare seen in the left humerus in the CT images was covered with a thin membrane during dissection. The presence of this membrane suggested that it might be due to the joint not being able to reach sufficient extension due to osteophytes forming in the bone. Additionally, it was concluded that CT may not recognize thin, non-mineralized septations, such as the membrane obliterating the supratrochlear foramen, as observed during necropsy.

Simulating Upper Eyelid Ptosis During Neuromodulator Injections-An Exploratory Injection and Dissection Study.

Aesthetic neuromodulator injections of the upper face are frequently performed to temporarily block muscular actions of the periorbital muscles to ultimately reduce skin rhytids. However, the adverse event rate in the literature for toxin-induced blepharoptosis ranges from 0.51% to 5.4%. To identify access pathways by which injected neuromodulator product can travel from extra- to intra-orbital and therefore affect the levator palpebrae superioris muscle. Nine non-embalmed human body donors were investigated in this study with a mean age at death of 72.8 (16.1) years. The 18 supraorbital regions were injected in 28 times (14 for supratrochlear and 14 for supraorbital) with 0.5 cc, whereas eight cases (four for supratrochlear and four supraorbital) were injected with 0.1 cc of colored product. Anatomic dissections were conducted to identify structures stained by the injected color. The results of this injection- and dissection-based study revealed that both the supratrochlear and the supraorbital neurovascular bundles are access pathways for injected neuromodulator products to reach the intra-orbital space and affect the levator palpebrea superioris muscle. Out of 36 conducted injection passes, seven (19.44%) resulted in affection of the sole elevator of the eyelid of which 100% occurred only at an injection volume of 0.5 cc and not at 0.1 cc. Clinically, the results indicate that a low injection volume, a superficial injection for the supraorbital location, and angling the needle tip away from the supratrochlear foramen (toward the contralateral temple) when targeting the corrugator supercilii muscles, can increase the safety profile of an aesthetic toxin glabellar treatment.

Macro‐anatomical investigations on the skeleton of the Egyptian hedgehog (Hemiechinus auratus aegyptius)

AbstractThe skeletal anatomy of wild animals plays a major role in their adaptation to their habitats. Information regarding the skeletal architecture of the Egyptian long‐eared hedgehog (Hemiechinus auratus aegyptius), a terrestrial and nocturnal insectivorous mammal, was lacking. Current work described the detailed bone formation of this species' skeleton grossly and morphometrically. Skeletons of five adults, apparently healthy hedgehogs of both sexes, aged 10 ± 2 months, were obtained. Preparation of the bones was accomplished by using a hot water maceration procedure. The skull was elongated. The external sagittal crest and temporal lines were unclear. The mental foramen was ventral to P2. The angular process of the mandible was large. The vertebral formula was C7, T13, L6, S3, Ca 13–15. The transverse foramen was absent in the seventh cervical vertebra. The sternum was formed of five sternal segments. There was a supratrochlear foramen on the distal part of the humerus diaphysis, connecting the radial and the olecranon fossae. The radius and ulna were fused by connective tissue. The carpals had three bones in the proximal row and four bones in the distal row. There were five metacarpals with five digits. The acetabulum was circular and had deep acetabular fossa. The foramen obturatum was ovoid. The pelvic symphysis was confined only to the ischium. The greater trochanter of the femur was lower than the level of the femoral head. The trochanteric fossa was deep and oval. Tibia and fibula fused distally. Two tarsals were in the proximal row and four in the distal row. There were five metatarsals with five digits. These findings provide the anatomical basis for understanding the adaptation mechanisms of this hedgehog species to their feeding habits and habitats and aim to help veterinarians, taxonomists, and wildlife biologists' in future biomedical and comparative skeletal anatomical studies.

Distal Humerus’ta Bulunan Supratrochlear Foramen ile İlgili Anatomik Çalışma

Aim: Supratrochlear foramen (STF) is the variation of the distal part of the humerus. The aim of this study is to reveal the frequency, morphology and morphometry of the STF in Turkish population and compare with previous studies.
 Materials and Methods: This study was performed with 116 dry humeri (61 right, 55 left). The translucent and opaque bony lamina between the coronoid fossa and the olecranon fossa and STF on the humerus were noted. STF was classified as oval, round, irregular, triangular, rectangular, sieve like, reniform, hourglass shaped. The frequency and morphometry of the STF were also evaluated.
 Results: The translucent type 88 (75.9%) bony lamina was found mostly between the coronoid and olecranon fossa. STF was detected on 19 (16.4%) humeri, 13 of them were on the left humeri and 6 of them were on the right humeri. The shape of the 16 of 19 STF were oval shaped. The mean values of the transverse and vertical diameter of STF, distance between the most medial points of the STF and medial epicondyle, the most lateral points of the STF and lateral epicondyle, distance between the most distal point of the STF and the lower edge of the trochlea humeri were found as 4.41±2.34 mm, 3.1±0.85 mm, 26.65±3.82 mm, 27.94±3.34 mm, 14.62±1.9 mm respectively.
 Conclusion: There are few studies on STF in Turkish population and we believe that this clinically important variation will contribute to anatomists, especially radiologists and orthopedists, in terms of awareness and knowing the frequency, morphology and morphometry of STF.

The Impact of Supratrochlear Foramen on Humeri's Medullary Canal Diameter and Its Surgical Implications.

Introduction Supracondylar elbow fractures are prevalent in the pediatric age group, and retrograde intramedullary nailing of the humerus is a common treatment approach. The anatomy of the medullary canal and the presence of the supratrochlear foramen (STF) significantly influence the stabilization of the nail. This study aimed to determine the incidence and morphology of the STF and compare the width of the medullary canal in humeri with and without the STF. Methods We examined 40 humeri bones with fused humeral epiphyses for the presence of the STF obtained from the Department of Anatomy's osteology collections. We studied the morphology and measured the dimensions of the foramen. We then compared the morphometric characteristics of humeri bearing the STF with those without it. We also took radiographs of all bones and measured the medullary canal width at three levels. We compared the measured width of the medullary canal in humeri between those with an STF and those without. This analysis was performed using IBM SPSS Statistics version 27.0 (Armonk, NY: IBM Corp.) for Windows and an unpaired t-test. We considered p-values of less than 0.05 as statistically significant. Results We found the STF in six bones (15%) as follows: four on the left side and two on the right. Humeri with the STF had smaller mean head circumference, length, and shaft circumference than those without the foramen. However, this difference was not statistically significant (p>0.05). The mean width of the medullary canal in humeri with the STF was significantly smaller (p<0.05) than in bones without the STF. Conclusions Our study revealed that humeri with an STF present a significantly smaller diameter of the medullary canal, which can impact surgical procedures like retrograde intramedullary nailing. Clinicians should consider this when planning surgeries to avoid iatrogenic fractures and enhance procedural efficiency. Our data also suggest that larger humeri are less likely to have an STF, potentially influencing pre-surgical planning and fracture risk assessment.

Anatomical variants complicating the posterior approaches towards the elbow joint

IntroductionAnatomical variants observed during the posterior approach to the elbow joint require special attention due to their clinical relevance. We aim to present a compendious review of described variants potentially encountered during the posterior approach towards the elbow joint to the experts in the elbow surgery.MethodsA narrative review of surgical and anatomical textbooks, as well as search of scientific databases was carried out.ResultsVariability of the subcutaneous nerves is important during incision planning. Accessory muscles such as dorsoepitrochlearis, chondroepitrochlearis, epitrochleoanconeus, subanconeus or supernumerary flexor carpi ulnaris may confuse even the senior surgeon during the dissection and possibly complicate the fracture reduction. Some bony variants such as supratrochlear foramen may lead to fracture or possibly interfere with the osteosynthesis placement. Accessory bones are also present in the region of the elbow joint. Those situated intra-articular may present with symptoms.ConclusionMany variants can be encountered in the area of the elbow joint and their knowledge is essential to truly understand its anatomy. The presented review enables easier orientation in the current literature with the aim on the posterior approach towards the elbow joint.

Osteology and radiographic anatomy of the thoracic limb of the greater cane rat (Thryonomys swinderianus).

The greater cane rat (Thryonomys swinderianus) is mainly distributed in the humid and sub-humid regions of the sub-Saharan Africa. It is believed to be the second largest African rodent. The aim of this study was to describe the normal osteology and radiographic anatomy of the thoracic limb of the greater cane rat as a reference for teaching, clinical use, anatomical studies and biomedical research. Five intact dead greater cane rats were used for radiographic examination. Radiographic findings were correlated with bone specimens. The clavicle was seen in all animals. The scapula was wide with well-developed acromion and coracoid process. The major and minor tubercles did not extend higher than the head of the humerus. The deltoid tuberosity was very prominent. The medial epicondyle was larger than its lateral counterpart, and the supratrochlear foramen was present. The radial tuberosity was further distally located. The ulnar head was well-developed, and the olecranon tuber was square-shaped. The distal physes for the radius and ulna appeared transverse. The carpus had eight bones. The manus presented with five widely spread digits. The first digit was reduced in size and placed such that the dorsal and palmar surfaces face almost medial and lateral, respectively. Additionally, two rudimentary digits were seen. Variations exist in the normal osteology and radiographic anatomy of the thoracic limb in different species. Knowledge of the normal osteology and radiographic anatomy of the thoracic limb of individual species is important for species identification and diagnosis of musculoskeletal diseases involving the thoracic limb.

Osseous variability around the elbow joint.

There are many osseous variants that occur around the elbow joint such as supracondylar process, supratrochlear foramen, accessory ossicles, and others. Scientific databases were searched for variants around the elbow joint. Elbow radiographs from our center demonstrating some of these findings were included in the study. The aim of the present review was to provide comprehensive information on the terminology, prevalence, history, etiology, and clinical importance of these variants. These anatomical variants are important for radiologists while interpreting radiographs, computed tomography, and magnetic resonance imaging for trauma and orthopedic surgeons during osteosynthesis at the distal humerus, proximal ulna, and radius.

Comparative Morphology of the Humerus of Rabbit, Guinea Pig and Mongoose

In this study, six animals of each rabbit, guinea pig and mongoose were used to compare the morphological features of the humerus. The biometrical parameters of the humerus, viz., mean length, width and circumference at the proximal extremity, distal extremity, and shaft were studied. In proximal extremity, anteriorly, the head of the rabbit humerus was comparatively thicker as compared to guinea pig and mongoose. The lateral tuberosity was large and less clearly divided in mongooses and the division was not visible in guinea pigs and rabbits. The lateral surface of the lateral tuberosity was found with a notch that was deep in mongooses and shallow in rabbit and guinea pig. The bicipital groove was very deep in guinea pig, less deep in rabbit and shallow in mongooses. The lateral surface of the shaft was spiral, smooth, and with musculo-spiral groove which was deep in mongooses, shallow in rabbit, and the groove was not visible in the guinea pig. On the lateral surface of the mongoose's proximal extremity of the humerus, the deltoid tuberosity was found sharp but in rabbit and guinea pig, it was blunt. The coronoid and olecranon fossa were deep in all the three species studied, but was found to be prominent in rabbit and guinea pig when compared to mongoose. Mongoose humerus was observed with an additional supracondylar foramen in the medial surface of distal one fourth of the shaft above the supratrochlear foramen.

Morphometric Evaluation of Rarely Seen Supratrochlear Foramen and Supracondylar Process in the Humerus in Turkish Population

Abstract Background: Sometimes seen distal to humerus foramen supratrochleare and supracondylar process are rare variations. Supracondylar process is a variations observed on the distal side of humerus. The supracondylar process is a variant located 1/3 distal side of the humerus. The supratrochlear foramen may appear between the coronoid fossa and olecra-non fossa. Since the foramen may appear in a semi-transparent form, it may be misdiagnosed as an osteolytic lesion. The aim of the present study was to identify the prevalence and morphology of supratrochlear foramen and the supracondylar process of the humerus inTurkish population . Furthermore, we believe considering these variations by looking at this variation in the previously taken radiological images of the people, help identification of that person in any forensic case.Materials and Methods: The present study was conducted on 460 humerus samples (237 right; 223 left) with unclear age and gender in the Anatomy Laboratories of Necmettin Erbakan Meram, KTO Karatay, Yozgat Bozok, Kayseri Erciyes Faculties of Medicine. Morphometric measurements of such formations on the humerus were performed through a digital calliper and osteometric board. Furthermore, along with supratrochlear typing, the prevalence in the process and humerus was also detected.Results: In the present study, the supracondylar process was detected in 11 (2.4%) individuals (4 right; 7 left); however, it was not detected in 449 (97.6%) humerus samples. The supratrochlear foramen was detected in 63 (13.7%) of 460 humeri. The foramen supratrochlear was seen in 10.8% of the humerus on the right side in 16.5% (29) and in 16.5% of the left humerus. The prevalence of both process and foramen on the humerus was 0.7% (3). The average lengths of right supracondylar process and left supracondylar process were 9.47±1.94 mm and 16.24±14.06 mm, respectively. The verti-cal diameter was 3.45±1.07 mm on the right supratrochlear foramen, and 3.57±1.17 mm on the left supratrochlear foramen; mean transverse diameter of the right foramen was 4.73±2.81 mm, and mean transverse diameter was detect-ed 4.41± 2.49 mm on the left. Conclusions: The prevalence of supratrochlear foramen and the supracondylar process was higher on the left side; howev-er, both are detected on the right side. We believe that the data obtained would be helpful for an orthopaedic surgeon during intramedullary nailing, and for differential diagnosis of some osteolytic lessons for a radiologist. In addition, these variations can be an important indicator in the differentiation of different races.Key Words: Humerus, Supracondylar process, Supratrochlear foramen, Morphometry, Variation

Morphometric Study of Supratrochlear Foramen of the Humerus Related with Clinical Implications in a Thai Population

Supratrochlear foramen (STF) is a perforation of bony wall that separates the olecranon fossa and the coronoid fossa. Its incidence varies among different races. The aim of this study was to investigate the prevalence and morphometry of supratrochlear foramen among Thai population. A total of 640 dry humeri from 320 skeletons, 160 paired humeri of each sex, and known age were collected to study the prevalence of STF. The prevalence is reported categorized by sex and the side of humerus to identify whether there is a correlation. STF is categorized by shape and their metrics measured with digital vernier calipers. The ratio of transverse diameter (TD) and distance from the medial epicondyle to the lateral epicondyle (DMLE) were calculated to represent the size of STF. From 640 humeri, 404 cases were translucent septum, 133 cases were opaque septum, and 103 cases were recorded as foramen. In this study, the majority of supratrochlear foramen were oval-shaped, followed by irregular-shaped and round-shaped foramen. The ratio between TD and DMLE was 0.09±0.44 mm on the right and 0.08±0.41 mm on the left which was not significantly different. The findings can be used to understand the variation and location of supratrochlear foramen to help radiologists and orthopedic surgeons to avoid misdiagnosis of cystic lesion at the distal humerus.

Anatomical and radiographic study on the appendicular skeleton of the Tamandua mexicana

Tamandua mexicana species has an important role in the natural ecosystem as a pest controller, feeding on insects such as termites. One of the main anatomical adaptations that this species has undergone has been to its thoracic extremities. Having detailed knowledge regarding the osteology of the thoracic limbs of T. mexicana provides a strong base for its application in clinical-surgical practice. In addition to collaborating with the greater understanding of animal physiology and behavior. Because there was a lack of description about the appendicular skeleton anatomy of this species, the objective of this investigation was to describe the osteology and the radiographic anatomy of the appendicular skeleton of the T. mexicana. The bones used belonging to the appendicular skeleton of two specimens of T. mexicana were properly cleaned using standard boiling and maceration techniques. The morphometry of the bones was performed using a measuring tape, pachymeter, and radiographies. With this study, it was possible to identify and describe the anatomical peculiarities such as the presence of the double scapular spine that shapes the caudolateral fossa, and at the end of the humerus, the supratrochlear foramen, in addition to a markedly prominent medial epicondyle. In addition, a difference was observed between metacarpal bones and the phalanges of the third digit compared to the other ones, as it is significantly thicker. These findings reinforced the evidence that a certain degree of anatomical specialization is a result of an adaptation of this species to its environment and diet. The knowledge provided by research like this contributes to the improvement of surgical techniques and diagnostic approach in the species.

A Comprehensive Study on Supratrochlear Foramen of Human Humerus and its Clinical Significance - A Review.

The lower end of humerus has numerous fossae which play a significant role during extreme movements. Coronoid fossa and olecranon fossa are separated by a delicate supratrochlear septum; occasionally septum has perforation and form an aperture, named as Supratrochlear foramen (STF). The knowledge of this foramen will be beneficial for anatomists, anthropologists, orthopedic surgeons, and radiologists. The aim of the present study was to establish the prevalence and morphometry of STF of the humerus in South Indian population and to correlate with the previous studies. The present prospective study was carried out with 274 (146 left sided + 127 right sided) dried humeri of unknown sex and age. The distal humeri were examined for the presence of STF, morphometry such as diverse shapes, vertical and horizontal diameters, and distance from STF to medial, lateral epicondyle and also to the inferior margin of trochlea using digital vernier caliper. In the present study, out of 274 dried humeri, 69 showed presence of STF, 163 were translucent and 42 were opaque. The prevalence of STF was 25.18%. After keen observation, shapes of the STF were categorized accordingly. The oval (42%) showed higher percentage whereas the other shapes showed as follows: - irregular (12%), round (19%), rectangular (12%), reniform (9.7%), sieve (7.3%) and triangular (2%). The mean vertical and transverse diameters of STF on the right side were 3.12 ± 1.09 and 5.5 ± 1.83mm and on the left side, it was 3.47± 1.32 and 4.9± 1.5mm respectively. The mean distance from STF to medial and lateral epicondyle on the right side was 25.12± 3.1 and 28.09± 2.3mm and for the left side 24.97± 2.9mm and 27.16± 2.4mm respectively. The anatomical knowledge regarding the supratrochlear foramen is much promising for the orthopaedic surgeons during intramedullary nailing for supracondylar fracture of humerus. STF appears as a radiolucent area in radiographs, which may pose a difficulty for the radiologist in differentiating it from an osteolytic or cystic lesion. In addition, STF is predominantly found in the primates, it may act an evolutionary link between the humans and lower animals.

Humeral intracondylar fissures in French bulldogs.

French bulldogs have previously been reported to be at an increased risk of developing humeral condylar fractures (HCF). Humeral intracondylar fissures (HIF) are thought to be a predisposing factor for HCF occurrence in skeletally mature dogs particularly when the fracture occurs during normal activity. We hypothesised that HIF may be a predisposing factor for HCF in French bulldogs. A retrospective case series of nine French bulldogs that had sustained HCF and where CT was performed prior to surgery. Five of the fractured humeri had sclerosis adjacent to the fracture site. Six of the contralateral intact humeri were diagnosed with HIF on the basis of a partial (2/6) or complete (4/6) hypoattenuating area extending between the distal articular surface and the supratrochlear foramen in the sagittal plane, with adjacent sclerosis (6/6). Recognition of sclerosis at the intracondylar fracture surface on CT can prompt suspicion that HIF preceded HCF. A predisposing HIF has potentially great clinical significance for this breed if we draw parallels with breeds such as the springer spaniel for whom HIF and HIF-associated condylar fracture is well documented.

Skeleton Growth in Guinea Pigs and Humans

Every animal has a skeleton made up of many different bones. Bones are vital. Without bones we would not be able to move, protect our internal organs, store important minerals, or even make some cell types! When we are young, in addition to growing, our bones must develop into specific shapes. This article describes how and why bones grow and heal in humans and guinea pigs. Using a special imaging technique called micro-computed tomography, we will show you the unique structure of some guinea pig bones and how animals of different ages have important bone variations. We will also discuss how the fascinating discovery of a hole in a bone, called a supratrochlear foramen, was described for the first time in a species. We will also answer questions, such as “how can you keep your bones healthy” and “what happens to astronauts’ skeletons in space?”

Incidence of supratrochlear foramen of humerus

Introduction: The supratrochlear foramen of humerus is a small hole located above the trochlea of humerus. The supratrochlear foramen was first described by Meckel in 1825. The knowledge of the presence of supratrochlear foramen in the humerus is important for preoperative planning and management of supracondylar fractures and the interpretation of the abnormalities in the radiographs. Materials and Methods: The study was conducted in Jawaharlal Nehru Institute of Medical Sciences, Imphal. 60 dry humerus were studied. The parameters of the humerus. Supratrochlear foramen were measured with digital vernier caliper The supratrochlear foramen observed were photographed. Result and conclusion: The supratrochlear foramen was observed in 5 humerus. The supratrochlear foramen so observed were all on the left side. The incidence of supratrochlear foramen according to our present study is 8.33%. Two of the supratrochlear foramen observed were circular in shape . Another two were oval in shape .The fifth one was a slit. The present study may help the researchers in comparing the incidences of supratrochlear foramen of humerus. KEY WORDS: Humerus, Supratrochlear foramen of humerus.

Biomechanical Comparison of External Fixation and Double Plating for Stabilization of a Canine Cadaveric Supracondylar Humeral Fracture Gap Model.

Successful stabilization of comminuted supracondylar humeral fractures is challenging, and biomechanical studies are scarce. This study compares double-plate (DB-PLATE) and linear external fixator with an intramedullary pin tie-in (ESF-IMP) fixation techniques in a cadaveric gap model. The hypothesis was the DB-PLATE construct would be stiffer, stronger and more resistant to repeated loading than the ESF-IMP construct in both cyclic and load-to-failure axial compression testing. A 2 cm ostectomy was performed on 10 pairs of canine cadaveric humeri proximal to the supratrochlear foramen. Stabilization was with DB-PLATE (n = 10) or ESF-IMP (n = 10). Cyclic testing was performed by applying a 200 N load at 2 Hz for 63,000 cycles. Axial compressive load to failure testing followed. Data analysed included dynamic stiffness, stiffness and yield load. No constructs failed during cyclic testing or lost stiffness over time. Mean dynamic stiffness over the final 100 cycles was greater for DB-PLATE compared with ESF-IMP. Mean stiffness of DB-PLATE in load-to-failure testing was not different than ESF-IMP. Yield load of DB-PLATE was higher than ESF-IMP. Both DB-PLATE and ESF-IMP survived cyclic testing with no change in dynamic stiffness. DB-PLATE was stronger than ESF-IMP in load-to-failure testing, which may make this construct preferable when prolonged healing or poor patient compliance is anticipated. Results suggest that either method may be appropriate for fixation of comminuted supracondylar humeral fractures.

The Supratrochlear Foramen of Adult Humerus and its Clinical Considerations

The Supratrochlear Foramen of Adult Humerus and its Clinical Considerations

Supratrochlear foramen frequency In three Iraqi populations

The supratrochlear foramen (STF) is a perforation in the septum that separates the coronoid fossae and the olecranon, in the distal portion of the humerus. The supratrochlear foramen is present in some humans, with an incidence rate that varies greatly between populations. There are currently no studies in the literature on the frequency of the STF in Iraqi populations.This study details new data on the frequency of the supratrochlear foramen among three distinct populations (Kurdish, Yazidi and Arab) within Iraq. The STF was studied in 206 skeletonized adult remains (2 females, 204 males) of the Yazidi population, 49 skeletonized adult female of the Kurdish population, and 51 skeletonized adult male remains sampled of the Arab population. The overall frequency of STF was 25.98%, 30.61%, and 21.56% for Yazidi, Kurdish, and Arab populations, respectively, and the total general frequency was 25.81%. These percentages fall within a medium to high range distribution when compared to other populations studied in previous research. The present provides new data to the literature on STF. It is important because it sheds light into the frequency of this feature between different populations of close geographical regions. Moreover, researchers can use this initial study as basis for clinical, radiological, and anatomical considerations related to that anatomical area.

Multidisciplinary studies of heavily fragmented and commingled ancient Egyptian human remains found in KV 40 (Valley of the Kings, Luxor, Egypt): A pragmatic workflow and first results

IntroductionFor archaeological projects, a systematic study of recovered human remains is essential to determine the individual characteristics of buried individuals. This publication presents a transdisciplinary workflow specially adapted for the study of heavily fragmented and commingled skeletonized or mummified ancient Egyptian human remains as found in tomb KV 40 during excavations as part of the “University of Basel Kings’ Valley Project” in the Valley of the Kings, Luxor, Egypt. Furthermore, anthropological data from this investigation are presented, and challenges and best practices of corresponding state-of-the-art investigation methods under such field conditions are discussed. Materials and methodsSkeletonized remains were first examined anthropologically. Mummified remains or those showing pathological alterations were X-rayed beforehand for non-invasive assessment of bone morphology and possible differential diagnoses. Measurements, X-ray and photographic images, as well as any additional information, were digitally stored in a specially developed database for later “off-field” analysis. ResultsThe developed workflow proved practicable and highly efficient. The minimum number of individuals (MNI = 83), age and sex distribution, adult stature, as well as the prevalence of anatomical variants (e.g., 23 individuals with supratrochlear foramen) and pathologic alterations could be established. Discussion and ConclusionDespite being fragmented and scattered as a result of looting and fire, these recovered human remains provided valuable insights into living conditions, demography and state of health during the 18th and 22nd − 25th dynasty in ancient Egypt (ca. 1370 and ca. 900–700 BCE). The results presented here, therefore, highlight the potential and the need for a trans disciplinary yet pragmatic approach for the study of such heavily commingled material.