The article presents the results of research work carried out in the direction of studying the influence of biological fertilizers on the yield and qualityof the Tamasha potato variety on heavy loam dark chestnut soils of Central Kazakhstan. It was carried out on a land plot with a humus content of 2.73-2.79 %, total nitrogen - 0.147-0.172 %, total phosphorus - 0.20- 0.25 %, a high level of supply of mobile phosphorus and potassium, a low content of nitrate nitrogen, a weakly alkaline soil pH. The research work carried out showed that potatoes have a high need for biological fertilizers, which, according to the types of fertilizers, gave an additional yield of up to 20 %, and also had a positive effect on quality indicators. It was shown that the effectiveness of biological fertilizers depends not only on its composition, but also on the influence of external factors, including first the soil conditions and the supply of potatoes with macronutrients.