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  • Substance Use Disorder Treatment
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Articles published on Substance Use Disorder

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  • New
  • Research Article
  • Cite Count Icon 1
  • 10.1016/j.josat.2026.209907
Understanding health literacy and perceptions of substance use disorder among racial and ethnic minority communities: Insights from the health belief model.
  • May 1, 2026
  • Journal of substance use and addiction treatment
  • Amanda I Aguila Gonzalez + 1 more

Understanding health literacy and perceptions of substance use disorder among racial and ethnic minority communities: Insights from the health belief model.

  • New
  • Research Article
  • 10.1016/j.drugalcdep.2026.113095
Development and psychometric evaluation of two substance use disorder knowledge scales.
  • May 1, 2026
  • Drug and alcohol dependence
  • Valerie A Earnshaw + 5 more

Development and psychometric evaluation of two substance use disorder knowledge scales.

  • New
  • Research Article
  • 10.1016/j.drugalcdep.2026.113097
Improving social cognition in individuals with substance use disorders through the E-motional training program: A pilot study.
  • May 1, 2026
  • Drug and alcohol dependence
  • Adolfo Piñón-Blanco + 20 more

Improving social cognition in individuals with substance use disorders through the E-motional training program: A pilot study.

  • New
  • Research Article
  • 10.1016/j.drugpo.2026.105244
'I don't really want to speak up because they're on a different level to me': The stigma of not engaging in trauma talk.
  • May 1, 2026
  • The International journal on drug policy
  • James Windle + 1 more

The stigma attached to substance use disorder (SUD) can prevent entry into, and engagement with, treatment services. This paper provides an initial exploration into what could be an emerging trend using a case study approach. Semi-structured interviews were conducted with 15 women who have used, or were currently using, residential or community-based addiction services in Cork (Ireland). Some participants reported the well documented stigma attached to SUD as a barrier for entry into, and engaging with, the recovery process. Two participants reported feeling ashamed of being unable to identify specific traumas that could account for their substance use. They felt the stereotype of 'the addict' having had a traumatic life did not map onto their experiences, and felt stigmatised by others within recovery for this. Consequently, they questioned whether they had a SUD and should access treatment, and this initially prevented them from engaging in therapy. This paper does not refute the association between trauma and SUD. Rather it argues that common misunderstandings of trauma and substance use, and increased use of trauma talk, may have contributed to a new form of stereotype that some with SUDs must navigate.

  • New
  • Research Article
  • 10.1016/j.euroneuro.2026.112783
Predictors of treatment success in patients with substance use disorder (SUD) and co-morbid attention deficit/hyperactivity disorder (ADHD): Results from the International Naturalistic Cohort Study of ADHD and SUD (INCAS).
  • May 1, 2026
  • European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology
  • Christoffer Brynte + 20 more

Comorbid attention deficit/hyperactivity disorder (ADHD) and substance use disorder (SUD) is associated with poor treatment outcomes. This international multi-center observational prospective cohort study aimed to gain knowledge about predictors of treatment outcomes in adult SUD+ADHD patients. Data was collected from June 2017 to May 2021 at baseline, four weeks, three months, and nine months at twelve treatment services in nine countries. Main outcomes were: Treatment retention, ≥30% reduction from baseline to follow-up according to the adult ADHD self-report scale (ASRS-18), and self-reported substance use at three-month follow-up. A total of 137 adult females (24 %) and 441 adult males (76 %) were enrolled. Receiving stimulant treatment for ADHD was significantly associated with better treatment retention (OR: 2·4, 95% CI: 1·4-4·2), ≥30% reduction in ASRS total score (OR: 2·6, 95% CI: 1·2-6·1), and fewer heavy drinking days (IRR: 0·24, 95% CI: 0·13-0·42) at three months. Psychosocial treatment for ADHD was independently and significantly associated with fewer heavy drinking days at three months (IRR: 0·27, 95% CI: 0·14-0·51). In summary, treatment of ADHD in SUD+ADHD patients was related to improvements in ADHD-symptoms, treatment retention and fewer heavy drinking days at follow-up. These findings highlight the importance of ADHD treatment provision in this population. Future RCTs are warranted to confirm these results and should assess combinations of ADHD treatments and SUD treatments using different doses of stimulants. Trial Registration: ISRCTN (https://doi.org/10.1186/ISRCTN15998989).

  • New
  • Research Article
  • 10.1016/j.josat.2026.209912
Hope, resilience, and ambiguous loss among affected family members of individuals with substance use disorders.
  • May 1, 2026
  • Journal of substance use and addiction treatment
  • Alexia Florentin + 1 more

Hope, resilience, and ambiguous loss among affected family members of individuals with substance use disorders.

  • New
  • Research Article
  • 10.1016/j.drugpo.2026.105238
Family members' perspectives of laws, policies and practices in substance use disorder treatment: Systemic alienation of the family in Canada.
  • May 1, 2026
  • The International journal on drug policy
  • Oona St-Amant + 8 more

Family members' perspectives of laws, policies and practices in substance use disorder treatment: Systemic alienation of the family in Canada.

  • New
  • Research Article
  • 10.1016/j.josat.2026.209906
Revealing patterns of indigenous neglect in co-occurring posttraumatic stress and substance use disorder research: A systematic review.
  • May 1, 2026
  • Journal of substance use and addiction treatment
  • Mallet R Reid + 3 more

Revealing patterns of indigenous neglect in co-occurring posttraumatic stress and substance use disorder research: A systematic review.

  • New
  • Research Article
  • 10.1016/j.psychres.2026.117030
A multicenter study to validate the Brief Cognitive Status Examination as a screening tool for the detection of cognitive impairment in a substance use disorder population over 45 years of age in a Spanish population.
  • May 1, 2026
  • Psychiatry research
  • Elena Ros-Cucurull + 19 more

A multicenter study to validate the Brief Cognitive Status Examination as a screening tool for the detection of cognitive impairment in a substance use disorder population over 45 years of age in a Spanish population.

  • New
  • Research Article
  • 10.1016/j.brainresbull.2026.111842
Ketamine-induced changes in accumbal glutamate and their association with altered states of consciousness.
  • May 1, 2026
  • Brain research bulletin
  • Ladina Philomena Gubser + 4 more

Ketamine-induced changes in accumbal glutamate and their association with altered states of consciousness.

  • New
  • Research Article
  • 10.1016/j.neuroimage.2026.121858
Potentially traumatic events and substance use do not predict changes in resting state functional connectivity in early adolescence.
  • May 1, 2026
  • NeuroImage
  • Herry Patel + 5 more

Potentially traumatic events and substance use do not predict changes in resting state functional connectivity in early adolescence.

  • New
  • Research Article
  • 10.1111/acel.70499
Brain Aging Mediating Heart Imaging-Derived Phenotypes and Mental and Nervous System Disorders.
  • May 1, 2026
  • Aging cell
  • Zairen Zhou + 10 more

Mental and nervous system disorders often co-occur with cardiovascular diseases in aging populations, yet the biological relationships underlying these associations remain incompletely understood. Using heart and brain imaging data from 33,573 UK Biobank (UKB) participants, we developed a brain age prediction model to estimate the brain age gap (BAG), an imaging-based marker of brain aging. We then examined BAG as a mediator between 82 cardiac imaging-derived phenotypes (IDPs) and 11 disorders. Sixty-one cardiac IDPs, particularly those related to the atria and left ventricle, were significantly associated with BAG, with several also related to mental and nervous system disorders. Mediation analyses revealed that BAG significantly mediated 18 associations between heart and substance abuse, mood, and neurotic disorders. Furthermore, we observed a total of 49 significant associations, where lifestyle factors, including smoking and physical activity, were related to heart-brain aging-disorder relationships. These findings highlight brain aging as a potential pathway linking cardiovascular health to diverse brain disorders in aging populations.

  • New
  • Research Article
  • 10.1016/j.jpsychires.2026.01.059
Planning and problem solving across multiple psychiatric disorders in young adults.
  • May 1, 2026
  • Journal of psychiatric research
  • Raj A Shetty + 1 more

Planning and problem solving across multiple psychiatric disorders in young adults.

  • New
  • Research Article
  • 10.1016/j.ahjo.2026.100764
The incidence and associated factors of pulmonary embolism after cardiac surgery: A retrospective nationwide inpatient sample database study
  • May 1, 2026
  • American Heart Journal Plus: Cardiology Research and Practice
  • Lili Zheng + 10 more

The incidence and associated factors of pulmonary embolism after cardiac surgery: A retrospective nationwide inpatient sample database study

  • New
  • Research Article
  • 10.3928/02793695-20260414-01
Nurses' Relational Authenticity and Empathy Through the Lens of Peplau's Theory of Interpersonal Relations and Their Correlation With Recovery Capital in Individuals With Substance Use Disorder: A Rural-Urban Comparison.
  • Apr 28, 2026
  • Journal of psychosocial nursing and mental health services
  • Rasha Salah Eweida + 5 more

To compare relational authenticity and empathy among rural and urban psychiatric-mental health nurses and examine their correlation with recovery capital in individuals with substance use disorder (SUD) using Peplau's Theory of Interpersonal Relations as a conceptual framework. Using a descriptive comparative study design, 278 participants were recruited from rural and urban psychiatric settings. Nurses (n = 152) completed the Kernis-Goldman Authenticity Inventory, Interpersonal Reactivity Index, and Working Alliance Inventory-Short Version. Patients (n = 126) with SUD were evaluated using the Brief Assessment of Recovery Capital. A statistically significant difference was observed in responses regarding the relational orientation domain of authenticity, as well as the fantasy and empathic concern dimensions of empathy (p = .013, p = .042, and p = .022, respectively). Empathy and therapeutic alliance were identified as significant independent predictors of authenticity among nurses. Higher levels of empathy and authentic engagement were positively associated with increased recovery capital in patients with SUD. Empathetic and authentic nurse-patient relationships, as framed by Peplau's theory, are critical to supporting recovery in individuals with SUD. Enhancing these relational competencies, especially in under-resourced rural settings, may improve mental health outcomes and reduce disparities in recovery support.

  • New
  • Research Article
  • 10.1016/j.josat.2026.209992
Comorbidities of substance use: Opportunities realized and future needs.
  • Apr 23, 2026
  • Journal of substance use and addiction treatment
  • Judith Feinberg + 16 more

Comorbidities of substance use: Opportunities realized and future needs.

  • New
  • Research Article
  • 10.1177/10748407261442563
Exploring the Distinction Between Support and Enabling in Families With Substance Use Disorder.
  • Apr 22, 2026
  • Journal of family nursing
  • Alex Elswick + 1 more

Substance use disorders (SUDs) are a pervasive public health problem facing families in the United States. Although families are frequently urged to support loved ones who have SUDs and cautioned against enabling them, there is a dearth of literature that distinguishes between supporting and enabling. This phenomenological study examined the experiences of parents (n = 8) with adult children with SUD who were currently in recovery. The primary research question in this study centers on how parents navigate their loved one's SUD, attempting to support recovery without enabling addiction. Three themes emerged from the data, including (a) addiction and recovery knowledge, (b) support group philosophy, and (c) differentiation. The results of this study add to the literature by demonstrating the importance of respective family support group affiliation on family's perception of enabling versus supporting. More research is needed to compare and contrast family support groups and their respective philosophies.

  • New
  • Research Article
  • 10.1080/00952990.2026.2643888
Temporal trends in the burden of drug use disorders in East and Southeast Asian countries and territories from 1990 to 2021: findings from the Global Burden of Disease Study 2021
  • Apr 19, 2026
  • The American Journal of Drug and Alcohol Abuse
  • Jiahe Liu + 6 more

ABSTRACT Background: East and Southeast Asia face a severe drug epidemic. A detailed analysis of specific drug use disorders (DUDs) is urgently needed to inform targeted interventions. Objective: To quantify trends in the burden of four DUDs in East and Southeast Asia from 1990 to 2021. Methods: Using Global Burden of Disease Study 2021 data, we analyzed trends (1990–2021) in incidence, prevalence, and DALYs for four DUDs across 20 countries/territories. Estimated annual percentage changes and age-period-cohort models assessed trends and independent effects. Results: Significant disparities were observed. Amphetamine DALYs were higher in East Asia (41–79 per 100,000), while cocaine DALYs peaked in high-income Asia-Pacific (15–16 per 100,000). Amphetamine-related DALYs declined sharply in East Asia (net drift: −3.08%; 95% CI: −3.20 to −2.95, p < .001) but increased in Southeast Asia (0.16%; 0.11 to 0.22, p < .001). Cannabis-related DALYs rose in East Asia (0.27%; 0.2 to 0.35, p < .001). Cocaine-related DALYs fell markedly (−3.81%; −3.95 to −3.68, p < .001). Age effects peaked at 15–34 years. Conclusions: The patterns of drug prevalence and their changing trends in East Asia and Southeast Asia show regional characteristics. The proliferation of amphetamines is becoming increasingly severe in Southeast Asia, while in East Asia, although some success has been achieved in controlling other drugs, risks related to cannabis are continuously rising. Public health strategies must focus on subregional interventions, prioritizing the growing problem of amphetamines in Southeast Asia and the emerging trend of cannabis use among young people.

  • New
  • Research Article
  • 10.1177/00220426261446257
Patient-Reported Outcome Measures (PROMs) During and After Residential Substance Use Disorder Treatment: A Prospective Cohort Study in Belgium
  • Apr 18, 2026
  • Journal of Drug Issues
  • Amine Zerrouk + 8 more

This prospective multicenter cohort study examined changes in patient-reported outcome measures (PROMs) among 161 men and women entering residential substance use disorder (SUD) treatment in Belgium and explored how treatment setting and sociodemographic factors influence outcomes. PROMs were assessed at baseline and after 45, 90, and 180 days using the PROMIS-GH (general health), WHOQoL-BREF (quality of life), and SURE-NL (recovery). Linear mixed models showed significant improvements in mental and physical health, and in all quality of life (QoL) domains except for social relationships. Psychological and physical health improvements plateaued, while perceived QoL and environmental domains improved linearly. Males scored higher in psychological health whereas treatment modalities differed in psychological health and social relationships. Recovery scores remained consistently high, possibly due to ceiling effects, underscoring the importance of the timing and context of PROM assessment. Integrating PROMs into routine care has the potential to support patient-centered practices and enhance treatment outcomes in SUD services.

  • New
  • Research Article
  • 10.1007/s11606-026-10394-7
Impact of State Telemedicine Policies on Substance Use Disorder Treatment During the COVID-19 Pandemic.
  • Apr 17, 2026
  • Journal of general internal medicine
  • Matthew D Eisenberg + 9 more

The COVID-19 pandemic disrupted traditional substance use disorder (SUD) treatment modalities, prompting innovative telemedicine solutions. To evaluate the association between state-level telemedicine policies and SUD treatment during the COVID-19 pandemic. An augmented synthetic control analysis comparing changes in SUD treatment before and after the implementation of telemedicine policies in states that adopted these policies to changes in SUD treatment in comparison states without these policies from 2018 to 2022. This study utilized a comprehensive policy database merged with de-identified patient claims data from the OptumLabs® Data Warehouse. Individuals aged 18 in only fully insured commercial, private plans subject to state insurance policies between January 2018 and December 2022. Combined implementation of three state telemedicine policies during the early months of the COVID-19 pandemic (March-July 2020), including telemedicine coverage parity, telemedicine payment parity, and in-person relationship waivers. SUD treatment initiation and continuation, measured at the patient-month level and aggregated to the state-month level for analyses, with subgroup analyses for opioid use disorder (OUD) and alcohol use disorder (AUD) treatment. Implementation of the three policies was associated with average effects of less than 0.006 percentage points in the proportion of adults initiating SUD, AUD, or OUD treatment between March/April 2020 and December 2022, with confidence intervals not exceeding a 0.02 percentage point increase or decrease (p > 0.05). Among adults receiving treatment prior to the COVID-19 pandemic, these policies were associated with an estimated average change of less than 1.5 percentage points in the proportion of adults receiving SUD, AUD, or OUD treatment, with confidence intervals not exceeding a 4.5 percentage point increase or decrease (p > 0.05). Our study did not identify impacts of state telemedicine coverage parity, payment parity, and in-person relationship waiver policies on SUD treatment during the COVID-19 pandemic.

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