Groups Of Subjects Research Articles

Diagnostic value of whole blood cell parameters logistic regression model for radiation injury on radiation workers

Objective: To explore the diagnostic value of whole blood cell parameters logistic regression model for radiation injury on radiation workers by comparing the differences of whole blood cell parameters between occupational radiation injury population and occupational health examination population. Methods: In February 2023, 184 radiation workers who received occupational health examinations in our hospital and occurrenced chromosome aberration from July 2021 to July 2022 were retrospectively selected as the radiation injury group. And other 184 radiation workers encountered in the same period without chromosome aberration occurrence were selected as the control group. Collected whole blood cell parameters from two groups of research subjects, conducted comparative analysis, constructed a logistic regression model, and evaluated the diagnostic value of the logistic regression model for radiation injury on radiation workers by receiver operating characteristic curve (ROC) and area under curve (AUC) . In addition, with the same standard, 60 radiation workers with chromosome aberration and 60 radiation workers without chromosome aberration from August 2022 to January 2023 were included in the validation queue to validate the logistic regression model. Results: Neu_X, Neu_Y, Neu_Z, Lym_X, Lym_Y, Lym_Z, Mon_X, Mon_Y, Mon_Z, Micro, MCHC in the radiation injury group were significantly higher than those in the control group, and the difference was statistically significant (P<0.05) . And MCV and Macro in the radiation injury group were lower than those in the control group, and the difference was statistically significant (P<0.05) . Moreover, logistic regression analysis showed that Lym_X, Lym_Y, Lym_Z, MCHC, Micro were all independent risk factors for diagnosing radiation injury on radiation workers (OR=1.08、1.02、0.99、1.06、51.32, P<0.05) . ROC curve analysis showed that the AUC, sensitivity, specificity, and accuracy of the logistic regression model based by Lym_X, Lym_Y, Lym_Z, MCHC and Micro in diagnosing radiation injury on radiation workers were 0.80, 85.9%, 65.8% and 75.9% respectively. The validation queue verified the logistic regression model and the AUC, sensitivity, specificity, and accuracy of the logistic regression model were 0.80, 81.7%, 71.7% and 76.7% respectively, the model fitted well. Conclusion: Radiation damage can cause changes in multiple whole blood cell parameters of radiation workers. The logistic regression model based by Lym_X, Lym_Y, Lym_Z, MCHC and Micro showed good diagnosis ability and can be used for the screening of radiation injury on radiation workers.

Evaluation of Subjective Tinnitus Severity and Distortion Product Otoacoustic Emissions and Extended High-Frequency Audiometry.

Tinnitus is a multifactorial phenomenon with quality-of-life detriments for those affected by it. We aim to establish a relationship between subjective tinnitus severity with objective audiometric data in the extended high frequency (EHF) from 9 to 16 khz and with distortion product otoacoustic emissions (DPOAE). We hypothesize that severe subjective tinnitus as measured by the Tinnitus Handicap Inventory (THI) does not correlate with increased hearing thresholds in the EHF range. Prospective. Single Tertiary Care Center. Patients identified with tinnitus and normal hearing thresholds within standard frequency range (250-8000 Hz) were consented for participation. Those with underlying otologic disease, trauma, radiotherapy, or ototoxic drug use were excluded. The THI questionnaire was given to eligible patients and audiometric test results were collected. THI scores were categorized by severity groups. An n = 20 to 30 was determined to have an effect size of 0.7 with a significance level of P = .05. THI and audiometric data were collected for 38 patients and categorized into mild (n = 18, 47.4%), moderate (n = 8, 21.1%), slight (n = 7, 18.4%), and severe (n = 5, 13.2%) tinnitus severity groups. Mean THI score was 32.3 ± 19.6 with a statistically significant difference in scores by assigned THI severity group (P < .01). There were no significant differences or linear relationship among hearing thresholds in EHF range or DPOAE stratified by subjective tinnitus group (P = .49, r2 = 0.10) CONCLUSION: Subjective tinnitus severity is not predictive of audiometric outcomes. This finding can be used as a counseling tool to help tinnitus patients manage symptoms, expectations, and overall treatment outcomes.

Group-by-Treatment Interaction Effects in Comparative Bioavailability Studies

Comparative bioavailability studies often involve multiple groups of subjects for a variety of reasons, such as clinical capacity limitations. This raises questions about the validity of pooling data from these groups in the statistical analysis and whether a group-by-treatment interaction should be evaluated. We investigated the presence or absence of group-by-treatment interactions through both simulation techniques and a meta-study of well-controlled trials. Our findings reveal that the test falsely detects an interaction when no true group-by-treatment interaction exists. Conversely, when a true group-by-treatment interaction does exist, it often goes undetected. In our meta-study, the detected group-by-treatment interactions were observed at approximately the level of the test and, thus, can be considered false positives. Testing for a group-by-treatment interaction is both misleading and uninformative. It often falsely identifies an interaction when none exists and fails to detect a real one. This occurs because the test is performed between subjects in crossover designs, and studies are powered to compare treatments within subjects. This work demonstrates a lack of utility for including a group-by-treatment interaction in the model when assessing single-site comparative bioavailability studies, and the clinical trial study structure is divided into groups.Graphical

Simulating rigid head motion artifacts on brain magnitude MRI data-Outcome on image quality and segmentation of the cerebral cortex.

Magnetic Resonance Imaging (MRI) datasets from epidemiological studies often show a lower prevalence of motion artifacts than what is encountered in clinical practice. These artifacts can be unevenly distributed between subject groups and studies which introduces a bias that needs addressing when augmenting data for machine learning purposes. Since unreconstructed multi-channel k-space data is typically not available for population-based MRI datasets, motion simulations must be performed using signal magnitude data. There is thus a need to systematically evaluate how realistic such magnitude-based simulations are. We performed magnitude-based motion simulations on a dataset (MR-ART) from 148 subjects in which real motion-corrupted reference data was also available. The similarity of real and simulated motion was assessed by using image quality metrics (IQMs) including Coefficient of Joint Variation (CJV), Signal-to-Noise-Ratio (SNR), and Contrast-to-Noise-Ratio (CNR). An additional comparison was made by investigating the decrease in the Dice-Sørensen Coefficient (DSC) of automated segmentations with increasing motion severity. Segmentation of the cerebral cortex was performed with 6 freely available tools: FreeSurfer, BrainSuite, ANTs, SAMSEG, FastSurfer, and SynthSeg+. To better mimic the real subject motion, the original motion simulation within an existing data augmentation framework (TorchIO), was modified. This allowed a non-random motion paradigm and phase encoding direction. The mean difference in CJV/SNR/CNR between the real motion-corrupted images and our modified simulations (0.004±0.054/-0.7±1.8/-0.09±0.55) was lower than that of the original simulations (0.015±0.061/0.2±2.0/-0.29±0.62). Further, the mean difference in the DSC between the real motion-corrupted images was lower for our modified simulations (0.03±0.06) compared to the original simulations (-0.15±0.09). SynthSeg+ showed the highest robustness towards all forms of motion, real and simulated. In conclusion, reasonably realistic synthetic motion artifacts can be induced on a large-scale when only magnitude MR images are available to obtain unbiased data sets for the training of machine learning based models.

Emotion recognition in amyotrophic lateral sclerosis in a dynamic environment

ObjectiveThe aim of our study was to measure the ability of ALS patients to process dynamic facial expressions as compared to a control group of healthy subjects and to correlate this ability in ALS patients with neuropsychological, clinical and neurological measures of the disease. MethodsSixty-three ALS patients and 47 healthy controls were recruited. All the ALS patients also underwent i) the Geneva Emotion Recognition Test (GERT) in which ten actors express 14 types of dynamic emotions in brief video clips with audio, ii) the Edimburgh Cognitive and Behavioral ALS Screen (ECAS) test; iii) the ALS Functional Rating Scale Revised (ALSFRS-R) and iv) the Medical Research Council (MRC) for the evaluation of muscle strength. All the healthy subjects enrolled in the study underwent the GERT. ResultsThe recognition of irritation and pleasure was significantly different between ALS patients and the control group. The amusement, despair, irritation, joy, sadness and surprise had been falsely recognized differently between the two groups. Specific ALS cognitive impairment was associated with bulbar-onset phenotype (OR = 14,3889; 95%CI = 3,96-52,16). No association was observed between false emotion recognition and cognitive impairment (F(1,60)=,56,971, p=,45,333). The number of categorical errors was significantly higher in the ALS patients than in the control group (27,66 ± 7,28 vs 17,72 ± 5,29; t = 8723; p = 0.001). ConclusionsALS patients show deficits in the dynamic processing of a wide range of emotions. These deficits are not necessarily associated with a decline in higher cognitive functions: this could therefore lead to an underestimation of the phenomenon.

Efektivitas Model Pembelajaran Picture and picture terhadap Hasil Belajar IPA Siswa di Sekolah Dasar

This study aims to evaluate the effectiveness of the Picture and picture learning model in improving science learning outcomes at SDN Inpres Kawae. The methodology employed was a quasi-experimental design with a subject group of 13 fifth-grade students, comprising 1 male and 12 female students. Data were collected using a test instrument to measure learning outcomes before and after the implementation of the Picture and picture learning model. The results indicate a significant improvement in students' learning outcomes. Before the implementation of the model, no students achieved the very high category (scores 76-100) on the pretest. However, after implementation, 7 students (about 45% of the total sample) reached the very high category on the posttest. This demonstrates that the Picture and picture learning model is effective in enhancing the effectiveness of science learning outcomes at SDN Inpres Kawae

Characterization of patient population receiving bioactive glass bone graft substitute as intraoperative treatment for orthopaedic trauma fractures

BackgroundBioactive glass synthetic bone grafts are used to treat osseous defects in orthopaedic surgery. Characterization of the clinical scenarios associated with bioactive glass use in the context of orthopaedic trauma, are not well established. This study aims to characterize population demographics, operative variables, as well as postoperative variables, for patients who required bone grafting for treatment of traumatic orthopaedic injuries and received a bioactive glass bone substitute intraoperatively. MethodsThe electronic medical record at a large Level I trauma center was queried for fracture patients between January 1st, 2019, and April 30th, 2022. Our retrospective cohort included fracture patients who received Fibergraft Matrix or Fibergraft Putty intraoperatively, and their respective control groups. This study ascertained patient demographic variables, operative variables, and postoperative variables. Differences in categorical variables were tested with Fischer's Exact Tests, while differences in continuous variables were tested with ANOVA. Statistical significance was determined as P < 0.05. If the overall Group model was significant for a given variable, post-hoc Fischer's Exact or Tukey HSD tests were used to assess pairwise significance between individual Group pairs. ResultsA total of four categories across our analysis of demographic, operative, and postoperative variables displayed significant differences amongst subject Groups (P ≤ 0.03). Individual groups were compared such that significant differences between subject groups could be appreciated for a specific variable. FM subjects had greater length of surgery, billable costs, and vitamin D supplementation at the time of surgery compared to FM controls. Similarly, FP subjects had greater length of surgery, billable cost, and implants used intraoperatively compared to FP controls. ConclusionThis analysis revealed Fibergraft patients to have greater length of surgery and billable cost, with respect to their matched controls. These data suggest that Fibergraft patients had more severe orthopaedic fractures compared to matched controls.

Assessment of titanium and cobalt urinary release from dental implants by ICP-MS: A case-control study

IntroductionDental implants are medical devices designed to replace missing teeth. They are usually made of titanium and cobalt. The present study aimed to evaluate the systematic release of cobalt and titanium in patients with dental implants. Materials and methodsThe present case-control study was conducted in dentistry establishments of the region of Chlef and included 24 patients with dental implants (group P) and 24 control subjects (group C). Titanium and cobalt urinary evels were quantified using Inductively Coupled Plasma Mass Spectrometry. The Shapiro–Wilk and Mann-whitney statistical tests were performed using R software. ResultsAssessed levels ranged from 0.001 to 0.025 and 0.020–3.900 ug.g−1 of creatinine for titanium and cobalt respectively. No statistically significant differences in titanium and cobalt urinary concentrations were found between the Group P and C (p = 0.521 and p = 0.577 for titanium and cobalt respectively). No statistically significant difference in titanium urinary levels was found between the smokers and non-smokers (p = 0.137). However, a statistically significant difference in cobalt urinary levels was found between the smokers and non-smokers (p = 0.002). In addition, a statistically significant difference in titanium and cobalt urinary levels was found between the subjects with and without orthopaedic implant (p = 0.001). ConclusionThe results revealed that there was no significant release of titanium and cobalt through dental implants in the studied population. Further studies with multidisciplinary approach, long-term follow-up and larger sample are required to evaluate other metals release from dental and orthopaedic implants.

Quantifying female upper lip lengthening with age by direct surface measurement: A guide for the lip lifting procedure

Upper lip lifting is a very popular procedure but there is no objective guidelines on how much skin has to be removed to obtain an optimal result. We have measured and compared the philtral height in two groups of young and old female Lebanese subjects. We have found a mean philtral height of 14.3±1.9mm in the young group and 19.8±2.4mm In the old group, with a mean philtral lengthening of 5.5±2.9mm. We suggest using these results to plan the amount of skin that has to be removed during a lip lift procedure.

Somatomotor-visual resting state functional connectivity increases after 2 years in the UK Biobank longitudinal cohort.

Functional magnetic resonance imaging (fMRI) and functional connectivity (FC) have been used to follow aging in both children and older adults. Robust changes have been observed in children, in which high connectivity among all brain regions changes to a more modular structure with maturation. We examine FC changes in older adults after 2 years of aging in the UK Biobank (UKB) longitudinal cohort. We process fMRI connectivity data using the Power264 atlas and then test whether the average internetwork FC changes in the 2722-subject longitudinal cohort are statistically significant using a Bonferroni-corrected -test. We also compare the ability of Power264 and UKB-provided, independent component analysis (ICA)-based FC to determine which of a longitudinal scan pair is older. Finally, we investigate cross-sectional FC changes as well as differences due to differing scanner tasks in the UKB, Philadelphia Neurodevelopmental Cohort, and Alzheimer's Disease Neuroimaging Initiative datasets. We find a 6.8% average increase in somatomotor network (SMT)-visual network (VIS) connectivity from younger to older scans (corrected ) that occurs in male, female, older subject ( years old), and younger subject ( years old) groups. Among all internetwork connections, the average SMT-VIS connectivity is the best predictor of relative scan age. Using the full FC and a training set of 2000 subjects, one is able to predict which scan is older 82.5% of the time using either the full Power264 FC or the UKB-provided ICA-based FC. We conclude that SMT-VIS connectivity increases with age in the UKB longitudinal cohort and that resting state FC increases with age in the UKB cross-sectional cohort.

Adult Attention Deficit-Hyperactivity Disorder is associated with Lewy Body Disease and Cognitive Impairment: A prospective cohort Study With 15-year Follow-Up

ObjectivesPast reports have suggested that attention-deficit/hyperactivity disorder (ADHD) may be a risk factor for Lewy body disease (LBD). To confirm this relationship, we conducted the present study. DesignA prospective observational cohort study with a follow-up to 15 years. SettingThe subjects were recruited from cognitive neurology clinics, where they attended for a cognitive complaint or health check-up. ParticipantsTwo groups of subjects: ADHD adults and healthy subjects. MeasurementsThe risk of dementia and LBD was estimated with Kaplan-Meier analysis comparing for the presence or absence of ADHD with the log-rank test. Predictors of conversion were assessed through separate univariate and multivariate Cox regression analyses, adjusting for several variables. ResultsThe baseline sample consisted of 161 subjects with ADHD and 109 without ADHD. At the end of the follow-up, 31 subjects developed dementia, 27 cases in the ADHD group and 4 in comparison group. Dementia with Lewy bodies (DLB) was the most frequent type (N:20) of which 19 corresponded to the ADHD group. The incidence of non-amnestic-MCI in the ADHD group was higher representing 67.1 % of these subjects (N:108), and 17.4% (N:19) of healthy cases. The hazard ratios for dementia and LBD in the multivariate adjusted model were 3.33 (95% CI 1.0915 to 10.1699) and 54.54 (95% CI 7.4849 to 397.5028), respectively in the ADHD group. ConclusionsThis study showed that adult ADHD is independently associated with an increased risk of LBD, dementia, and na-MCI. Future studies should clarify this relationship to develop preventive measures for these patients.

FTO Gene Polymorphism and Physical Activity in Relation to Body Mass Index

The aim of this study was to determine the frequencies of alleles and genotypes of the single nucleotide polymorphism of the FTO gene (rs17817449) and the intensity of physical activity in relation to the BMI of subjects in the student population. Genotyping was performed using the PCR-RFLP method. 94 subjects stated that they were not physically active, 57 subjects were moderately physically active and 52 were intensely physically active. In the total sample, the risk allele G of the investigated polymorphism rs17817449 of the FTO gene had a lower frequency (41.8%) compared to the normal allele T (58.13%). Although a higher frequency of the risk allele G was found in the group of overweight subjects compared to the group with BMI &lt; 25, the difference was not statistically significant (p &gt; 0.05).

Evaluation of a Lipid Profile in Normoglycemic and Pre-diabetic Saudi Office Employees in Makka Region: A Case-Control Study.

Diabetes mellitus (DM) poses a significant health challenge worldwide. The impact of a sedentary lifestyle in predicting and managing complications of diabetes represents an urgent need for health strategies. The objective of this study was to evaluate the lipid profile among normoglycemic and prediabetic Saudi office workers. The research was a case-control study carried out in Makkah al-Mukarramah (Kingdom of Saudi Arabia, KSA).Seventy-five office worker volunteers between the ages of 19 and 45 years were recruited for the study. The participants were divided into two groups: a control group of non-diabetic normal subjects (NGT) and prediabetic subjects with impaired fasting plasma glucose and/or impaired glucose tolerance (IGT), based on the American Diabetes Association recommendations. Measurements of glucose, hemoglobin A1C (HbA1C), total cholesterol (TC), triglycerides (TG), high-density lipoprotein (HDL), and low-density lipoprotein (LDL) were performed using standard procedures and commercial kits. Statistical analysis was performed to compare the lipid profile in the two groups, and a P-value of <0.05 was considered statistically significant. A proportion (58.7%) of the office workers are prediabetics; prediabetic office workers had higher total cholesterol compared to the controlgroup (p < 0.05). Triglyceride levels were higher in office workers with prediabetes compared to the normoglycemic group (p < 0.05). LDL levels were elevated in the prediabetic office workerscompared to the control group (p < 0.05). Office employees with prediabetes exhibit elevated levels of cholesterol, triglycerides, and LDL. The disturbance in lipid profile may be linked to impaired glucose tolerance in individuals with a sedentary lifestyle, such as office workers.

PENGARUH PELAKSANAAN PAÑCASĪLA BUDDHIS DAN PAÑCADHAMMA TERHADAP PEMBENTUKAN KARAKTER BUDDHIS SISWA SMP MAITREYAWIRA BATAM

This study seeks to quantify the impact of implementing Buddhist Pañcasīla and Pañcadhamma on the development of Buddhist character in eighth-grade students at Maitreyawira Junior High School in Batam. A quantitative approach was employed, using a survey method with a causality model. The subject group for this study consisted of 300 students in class VIII at Maitreyawira Junior High School in Batam. The sample of this research is all Buddhist students of class VIII which amounted to 177 students. The sampling technique was carried out using sampling with simple random sampling. Data collection techniques using a questionnaire. Assumption test uses normality, linearity, heteroscedasticity, and multicollinearity tests.The data analysis reveals a significant influence between the variables of Buddhist pañcasīla and Pañcadhamma implementation on the formation of Buddhist character. Thus, it is evident that the implementation of Buddhist pañcasīla and Pañcadhamma have significant effects on the formation of Buddhist character. The regression coefficient of the Buddhist pañcasīla variable (X1) is 2.5% or 0.025, whereas the Pañcadhamma variable (X2) shows a regression of 0.006 or 6%. Based on the coefficient of determination test, the Adjusted R square value is 0.008%. This indicates that only 8% of Buddhist Pañcasīla (X1) and Pañcadhamma (X2) variables can account for the variation in the variable of Buddhist character formation (Y) in Batam's Maitreyawira Junior High School students. The remaining 92% is attributed to the regression test.The study concludes that Buddhist principles such as Pañcasīla (X1) and Pañcadhamma (X2), along with the development of Buddhist character, significantly impact the formation of Buddhist character within Maitreyawira Junior High School students in Batam. The recommendation is for students to further develop the application of Buddhist Pañcasīla (X1) and Pañcadhamma (X2) beyond school and into their homes. It is also suggested that other researchers conduct more in-depth studies on these subjects

Narcissistic predispositions of self-harm in young women with and without depression

Introduction Diagnostic criteria for narcissistic personality disorder primarily focus on grandiosity and significance. In psychotherapeutic work, it is important to distinguish two subtypes of pathological narcissism: narcissistic grandiosity and narcissistic vulnerability. One of the manifestations of narcissistic traits is unstable or unformed self-esteem, manifested in attempts to conform to ideals. A part of modern society perceives the female body as an object that “needs to be looked at”. Self-objectification refers to a learned pattern of self-assessment of the importance of one’s body and appearance compared to other aspects of the self. Self-observation and comparison of oneself with others is one of the manifestations of self-objectification. With acts of auto aggression, the body becomes a tool or a means to solve psychological problems. In order for this to become possible, the ability to objectify your body “to look at it from the outside” plays an important role.ObjectivesAnalysis of the relationship between non-suicidal self-injurious behavior and narcissistic personality traits in young women with depression and young women without a psychiatric diagnosis.MethodsТhe study included 49 women divided into two groups. The first group included 24 patients with depression undergoing inpatient treatment (mean age 18.4). The second group included 25 healthy subjects (mean age 18 years). The methods: The answer to the question “Sometimes I purposely injure myself” was used as an indicator of self-harm (NSSI) (five-point Likert scale); “Ich structure test” (ISTA); “Physical Appearance Comparison Scale-Revised” (PACS-R).Results In the clinical group, a significant association of severity of NSSI with indicators of “deficit narcissism” was revealed (Spearman r=,534*). Correlations were found between the severity of NSSI and PACS-R (r=,344**). In the clinical group, there was no connection between “Comparison with others” and narcissistic traits. In a group of healthy subjects, significant associations of NSSI severity with “destructive narcissism” (,572**) and PACS-R (,576**) were revealed. In the clinical group, the severity of NSSI is associated with a more serious pathology - the lack of formation of “normal” narcissism, and in the healthy group it is more likely to be deformed narcissism. Self-objectification and comparison of oneself with others in the clinical group is not associated with manifestations of narcissistic traits, such connections are demonstrated in the group of healthy young women.ConclusionsIt is shown that in the clinical group of depressed young women, the severity of self-harming behavior is associated with “deficit narcissism”, and in healthy young women, first of all, with “destructive narcissism” with an increased need to compare themselves with others.Disclosure of InterestNone Declared

The Effect of Coaching Organization Citizenship Behavior Model Grow on Employee Performance

The ultimate aims of research are to determine the effectiveness of the GROW model of OCB (Organizational Citizenship Behavior) coaching in improving the performance of PT employees. X. The subjects in this research were employees at PT. X, totaling 16 people from the Marketing Division, were divided into two groups. This research uses an experimental method, with the GROW model OCB coaching intervention in the experimental group. Data analysis used a parametric test with the ANOVA mixed design data analysis technique which looked at the effect of treatment on two groups of subjects. The results of this research were an increase in the performance of the experimental group with a significance score of 0.003 &lt; 0.05. Apart from that, looking at the results of the pretest and posttest comparison, it was 71.6% when compared to the control group. This indicates that there is a significant difference between the group that was given the OCB coaching of the GROW model and the group that was not given the same treatment. In line with the result, companies can therefore improve the performance of their employees by performing the OCB coaching of the GROW model. In addition, it is essential that researchers study the factors that helpinfluence the success of the OCB coaching from different dimensions. Also, researchers should hire professional certified coaches to ensure that the coaching practice shows satisfactory results and is directed following the scientific method.

Model of Information Dissemination in the Context of Reputation Formation of an Auditing Company: Official Sources or “Word of Mouth”?

The reputation of auditing firms is of paramount importance in ensuring trust and confidence in financial markets. This article investigates the information dissemination model and its impact on the reputation formation of auditing companies, focusing on the choice between official sources (formal channels, corporate communications, regulatory disclosures, etc.) and word-of-mouth mechanisms (informal channels, client recommendations, corporate gossip, etc.). The research reveals the complex dynamics between formal and informal information dissemination strategies (official sources provide trust and transparency, while word-of-mouth mechanisms offer detailed information and trust) and their implications for reputation management in the auditing industry. The relevance of this research problem lies in the critical role of auditing firms in supporting transparency and honesty in financial reporting, especially after corporate scandals and regulatory scrutiny. The primary aim of this research is to understand the relative effectiveness of different information dissemination models in shaping the reputation of auditing companies. The choice of research subject is justified by the significant influence of auditing firms on financial markets, corporate governance, and investor trust. Using VOSviewer 1.6.16 software, the article conducts a bibliometric analysis of English-language articles and conference abstracts indexed in the Scopus database from 2007 to 2023 (1177 publications) using the keywords “Reputation” and “Auditing Firm.” The analysis confirms the increasing scholarly interest in this topic and identifies 8 thematic clusters, the largest of which combines corporate, image, and social reputation with stability and consistency. The empirical part of the research involves constructing a polygamous model similar to the SIR model, which describes the behavior of three groups of subjects depending on the presence of information and actions regarding its dissemination (active, passive, neutral). The article models the intensity of changes in the number of group members considering various phenomenological parameters (e.g., intensity of communicative processes between groups, structure of social system connections, mathematical expectation of time required for a subject to transition from one group to another, etc.). The results of this research have practical implications for auditing firms, regulatory bodies, and stakeholders in the financial sector. By understanding the relative strengths and weaknesses of different information dissemination models, auditing firms can adapt their communication strategies to effectively enhance their reputation. This research contributes to the ongoing discourse on reputation management and trust-building in financial markets.

Intervention with Purple Okra Pudding and Supplement to Improve Antioxidant Status in Healthy Adults

This research aimed to analyze the potency of purple okra-based products in improving the antioxidant status of healthy adults. Thirty adults with high body fat percentages were allocated into three groups: the first group was treated with 100 g of purple okra pudding/day, the second group was provided with a purple okra extract supplement that contained 3.80 g of extract/day, and the third group was a control group. The intervention was carried out for 28 days. All subjects were exposed to nutrition education, and data on their characteristics, food intake, and physical activity level were collected. The results showed that purple okra pudding and supplement had antioxidant activity of 0.39 and 455.39 mg AEAC/g extract, IC50 of 543.79 and 71.78 ppm, and total phenol of 6.21 and 24.49 mg GAE/g extract, respectively. There were significant differences among subject groups in energy, protein, and fat intake as well as physical activity level. The group treated with purple okra pudding showed a significantly higher ΔSOD after the intervention, most probably due to the role of antioxidants contained in purple okra in upregulating antioxidant defense. In contrary, there was a declining trend of ΔSOD in the group treated with purple okra extract supplement. The different effects observed between the two groups might be due to the different phenol contents between the two intervention products. This study showed that purple okra has the potential as a functional food and health supplement in improving the antioxidant status of healthy adults with high body fat percentages as indicated by a higher change of SOD level (0.08 u/mL) in comparison to the control (-0.07 u/mL).

A study on time schedules for construction projects in Hanoi, Vietnam

With its position as the capital, Hanoi is the political center as well as the second largest economic center of the country. Therefore, the city is always allocated a large budget in construction investment to create material facilities for political tasks and economic and social development. During the implementation of construction projects, a number of difficulties and limitations have appeared. In which, projects are delayed in construction and disbursement, reducing investment efficiency and not meeting the expectations of the government and people. From this fact, the authors have conducted a study to evaluate the causes affecting the time schedule of construction projects in Hanoi. The method F-APH (Fuzzy Analytic Hierarchy Process) was used to analyze data objectively and accurately about the causes affecting the time schedule. From there, these causes are classified into groups of subjective causes (from within the project) and groups of objective causes (from outside the project). The results show that subjective causes, originating from project participants, have a stronger influence than objective causes. A number of specific proposals to the actors involved in construction projects are made to eliminate or limit the impact of the causes of construction progress.

Prevalence of myopia in schoolchildren of a highly urbanized city in Eastern Siberia

Myopia is one of the most urgent problems of modern ophthalmology. Statistics show that the number of children and adolescents suffering from myopia is steadily increasing worldwide. But it also noted that in different regions of the Russian Federation, the proportion of children who are diagnosed with myopia may differ markedly. Purpose: to determine the prevalence and structure of myopia in schoolchildren of the city of Krasnoyarsk, depending on age and gender. Materials and methods. A survey of 3005 students of secondary schools in the city of Krasnoyarsk aged from 6 to 18 years, including 1,421 schoolboys and 1,584 schoolgirls, was conducted. Refraction was determined after cycloplegia using the autorefractometry method. Results. The predominant type of refraction in primary school students of both fi elds is emmetropia, myopia is in second place and other refractive errors are in third place. The prevalence of myopia in schoolchildren increases as they grow up. At the same time, in the schools of the city of Krasnoyarsk, already in the primary grades in the group of subjects of both sexes, the proportion of students with myopia was 17.9 %, in the middle – 36.8 %, and by the high classes it reached 49.7 %. When considering the data obtained, depending on gender, approximately the same proportions of myopia were found in primary grades in both schoolgirls (19.2 %) and schoolchildren (16.7 %), in middle grades, a statistically significant predominance of myopic refraction in girls, compared with boys (42.8 and 29.5 %, respectively, p &lt; 0.05). In high school, the proportion of myopia increases both in girls to 52.1 % and in boys to 47.2 %. The proportion of subjects with emmetropic refraction decreases as individuals of both sexes grow up. The percentage of other refractive errors remains without significant gender-age changes. Low myopia was the most common in all groups, but its percentage significantly decreased as they moved to higher grades, simultaneously with an increase in the proportion of moderate and high myopia. Conclusions. There is an increase in the prevalence of myopia in schoolchildren as they move to higher grades. A threefold increase in the proportion of myopia in high school compared with primary school was revealed. It is necessary to further study the prevalence of myopia in all Russian regions and develop preventive programs to control myopia in children.