Objectives: A kind of Artificial Neural Network (ANN) known as a Back Propagation Neural Network (BPNN) has been extensively applied in a variety of sectors, including medical diagnosis, optical character recognition, stock market forecasting, and others. Many studies have employed BPNN to create decision-support tools for doctors to use while making clinical diagnoses. Chronic Kidney Disease (CKD) is one such kind of disease which has been receiving due importance from the past decades due to lack of symptoms in its early stages. The goal of this work is to demonstrate the performance of Artificial Intelligent (AI) algorithms in the early detection of CKD. Method: We received 800 patients’ real-time data from DY Patil Hospitals for this investigation. Self-Acclimation Graded Boolean PSO (SAG-BPSO), a modified version of Particle Swarm Optimization (PSO), has been proposed and used in this study to accomplish feature selection. Cuckoo Search Algorithm (CSA) has been used to optimise the weights and biases of the BPNN. Finally, this hybrid model is combined with BPNN for final predictions. Finally, a comparison is made between few state of art algorithms and the proposed approach. Results: The accuracy noted on applying BPNN on the dataset was approximately 91.45%. The combined model of BPNN+SAGBPSO provided an accuracy of about 92.25%. The accuracy achieved for the hybrid model of BPNN+SAGBPSO+CSA was approximately near to 98.07%. Conclusions: This research used SAGBPSO for feature selection and CSA for finalizing the weights and biases of BPNN. The research implemented BPNN, BPNN+SAGBPSO and BPNN+SAGBPSO+CSA on our real time dataset. The proposed hybrid model BPNN+SAGBPSO+CSA outperformed all the state of art deep learning algorithms in terms of performance metrics.
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