Chondrosarcoma Of Spine Research Articles

Spinal chondrosarcoma following adenocarcinoma of the breast: case report

BACKGROUND Chest wall chondrosarcomas have been reported rarely in breast cancer patients treated with chest wall radiation therapy. However, there are no prior reports of spinal chondrosarcomas arising in patients with a history of breast adenocarcinoma. CASE DESCRIPTION A neurologically intact 53-year-old woman with breast adenocarcinoma and new onset back pain was evaluated. Magnetic resonance imaging of the spine revealed a tumor of the posterior elements of T7, impinging upon the spinal cord. A computed tomography guided needle biopsy of the spinal mass failed to yield diagnostic results. The patient underwent an open surgical biopsy and complete excision of a low-grade chondrosarcoma. The patient’s thoracic pain resolved after surgical excision of her thoracic tumor. She remained neurologically intact. Pathological examination of the tumor revealed a low-grade chondrosarcoma. CONCLUSION We present the first reported case of chondrosarcoma of the spine arising in a patient with a history of breast adenocarcinoma without prior irradiation. Solitary spinal tumors in patients with breast adenocarcinoma should not be assumed to be metastatic lesions, and chondrosarcoma should be included in the differential diagnosis of spinal lesions in this patient population. Experimentally, chondrosarcomas have been shown to be sensitive to circulating levels of estrogens, and this might explain an association with adenocarcinoma of the breast treated with tamoxifen.

Compresión medular dorsal por condrosarcoma vertebral primario

Chondrosarcomas are the second commonest type of bony tumors, although they are not commonly found to be vertebral. They may originate in healthy bone or develop in a cartilaginous lesion with sarcomatous degeneration. A 62 year old woman complained of pain in the back and weakness of her legs. Following magnetic resonance studies a tumour at the level of the D6-D7 vertebrae was diagnosed. This was operated on and an extradural tumour, a grade 11 chondrosarcoma was removed. A local recurrence was removed two years later and three years afterwards she is still asymptomatic. A spinal chondrosarcoma is a tumour which usually presents with local pain and signs of spinal involvement. On magnetic resonance it is iso-intense on T1 and shows up with contrast. The treatment of choice is radical surgery since it does not respond well to oncological treatment.

Primary Spinal Chondrosarcoma Localized in the Cervical Spinal Canal and Intervertebral Foramen

A 48-year-old male presented with a very rare case of spinal chondrosarcoma localized in the cervical spinal canal and intervertebral foramen, but without marked destruction of the vertebral column. Spinal chondrosarcoma is characterized by radiological evidence of destruction of the surrounding bone structure and mottled calcification. Magnetic resonance imaging was useful in the diagnosis and determination of the extent of this spinal chondrosarcoma. However, preoperative differential diagnosis of the tumor was not possible based on neuroimaging evidence.

Primary spinal chondrosarcoma with eighteen-year follow-up

Primary spinal chondrosarcoma with eighteen-year follow-up