Sodium Dodecyl Sulfate Molecules Research Articles

Influence of Adsorption Characteristics of Surfactants Sodium Dodecyl Sulfate and Aerosol–OT on Dynamic Process of Water-Based Lubrication

Surfactant solutions are widely used in industry, and their steady-state lubrication properties have been comprehensively explored, while the “dynamic process” between steady states attracts much less attention. In this study, the lubrication behaviors of sodium dodecyl sulfate (SDS) and sodium bis (2–ethylhexyl) sulfosuccinate (Aerosol–OT, AOT) solutions were comparatively and extensively discussed. Experimental results showed that the duration of the dynamic process of AOT solution lubrication was significantly shorter than that of SDS. The essence of the dynamic process was revealed from the aspects of the running-in of solid surfaces and the adsorption process of surfactant molecules. Unlike the general recognition that the friction force evolution mainly corresponds to the running-in of surfaces, this study indicated that the dynamic adsorption behavior of surfactant molecules mainly contributes to this process. Various experiments and analyses showed that the smaller steric hindrance and lower orientation speed of SDS molecules led to longer diffusion into the confined contact zone and a longer duration of friction force decrease. This work enhances our understanding of the dynamic friction process in water-based lubrication, which could also have important implications for oil-based lubrication and its industrial applications.

Molecular dynamics simulation of demulsification of O/W emulsion containing soil in direct current electric field

The collision under direct current (DC) electric field and non-electric field coalescence behavior of heavy oil droplets in complex oil-in-water (O/W) emulsion system were studied by molecular dynamics (MD). By changing the simulation parameters of electric field intensity, the movement of various molecules of emulsified oil droplets, such as Sodium dodecyl sulfate (SDS) molecules, silica nanoparticles (SiO2 NPs), asphaltene and resin molecules under six electric field intensities, and the aggregation process of colliding oil droplets after electric field excitation are discussed. At the same time, the radial distribution function and conformational statistics are used to analyze the charge distribution of oil droplets and the change of interaction force of different molecules from the microscopic point of view, and further explore the demulsification mechanism of oil droplets under the electric field. The simulation results show that when the electric field intensity is lower than 1.5 V/nm, the oily components of emulsified oil droplets cannot contact because of the blocking effect of SDS molecules. When the electric field intensity is greater than or equal to 1.5 V/nm, SDS molecules separate from the oil phase and enter the water phase, and emulsified oil droplets contact. The interface is a bridge structure formed by the face-to-face accumulation of asphaltene and resin. The existence of this structure is the key to further coalesce oil droplets into a whole. The local oil droplets will spontaneously coalesce without electric field, and the bridge structure formed by asphaltene will gradually disappear. SiO2 nanoparticles will promote the coalescence of oil droplets.

A feasible approach to tune the interaction of chitosan with sodium dodecyl sulfate

Interaction of binary chitosan/nonionic surfactant (NIS) system with sodium dodecyl sulfate (SDS) in aqueous solution is described using turbodimetry, light scattering, electophoretic mobility and cryogenic electron microscopy. The formation of insoluble CHI/SDS complexes is weakened with a decrease in molecular weight of chitosan and critical micelle concentration of NIS as well as with an increase in NIS concentration. Soluble chitosan/NIS complexes absorb SDS molecules until the charge of mixed chitosan/NIS/SDS complexes reaches a critical value that depends on chitosan molecular weight followed by aggregation of primary electrostatic complexes via hydrogen bonding to complex nanoparticles. In contrast to formation of asymmetric swarm-like structures in the binary chitosan/SDS system, the aggregation of complex nanoparticles in the ternary chitosan/NIS/SDS system occurs by a head-to-tail binding mechanism with formation of elongated filamentous microstructures. The finding can be promising for preparation of microbiologically stable pharmaceutical and cosmetic compositions and drug delivery systems containing mixed surfactants.

Investigation on the lead adsorption capacity of Iranian natural zeolite: modifications, structural effects, adsorption isotherms, kinetics, and mechanism studies

ABSTRACT Clinoptilolite (NZ) as a natural and cost-effective adsorbent, modified with two different methods. At the first stage, by sodium chloride solution to obtain NaCl-modified natural zeolite (NaCl-MNZ), then sodium dodecyl sulfate (SDS) was used to modify NaCl-MNZ (SDS-MNZ). Along with NZ, NaCl-MNZ, and SDS-MNZ, commercial NaY zeolite was also used for removing lead cations from synthesized wastewater. The adsorption of SDS molecules on the outer surface of zeolite was confirmed by FTIR and the specific surface area of the SDS-MNZ was decreased due to the coverage of smaller pores by anionic surfactant molecules. The zeta potential measurements also revealed that the modification process has decreased the surface charge of the zeolite significantly, which was favorable for the adsorption of Pb2+ cations and improved clinoptilolite performance. The non-linear adsorption kinetics and isotherms are best described by the pseudo-first-order and Sips model, respectively. The maximum adsorption capacity of lead ions were 25.8435, 39.5992, 38.5454, and 101.0240 (mg/g) for NZ, NaCl-MNZ and SDS-MNZ and NaY, respectively. The results indicated that the adsorption capacity of natural zeolites modified with NaCl and SDS were approximately 35% and 33% higher than that of the clinoptilolite alone.

Critical micelle concentration of SDS through DPD simulations using COSMO-RS–based interaction parameters, the thermal effects

In order to obtain the critical micellar concentration (CMC) for sodium dodecyl sulfate (SDS) in water at 288.15, 293.15, 298.15, 303.15 and 308.15 K, two approaches were employed: the first, consisting of experimental Isothermal Calorimetric Titration (ITC) and the second by using Dissipative Particle Dynamics (DPD) simulations. To determine the experimental CMC the calorimetric signal was treated with the software D/STAIN, obtaining values between 8.24 and 9.22 mM, which are in good agreement with other experimental determinations. Also the SDS micellization enthalpies found agree with previous experimental reports. The pairwise aij DPD interaction parameters, needed to run the simulations, were obtained from quantum chemistry calculations under the application of the COSMO-RS solvation scheme jointly with the Flory-Huggins theory. A series of systems with variable concentration of SDS in water were simulated for each temperature. Then, the analysis of the percentage of aggregation of SDS molecules at each temperature, enable to visualized the theoretical aggregation isotherms. By delimiting an experimental CMC window, the DPD aggregation isotherms were used to identify the concentration where either the monomeric or micellar states domain. Intersection of linear fits, in the monomeric and in the micellar regime produced theoretical CMCs values from 8.1 to 8.9 mM. These results compare favorably with the experimental determinations at each temperature.

The Effect of Na-Based Salts on Critical Aggregation Concentration of Aqueous Peg-Sds Mixtures

Critical aggregation concentration (CAC) is a well-known parameter used to study the interactions between constituents in an aqueous mixture containing surfactant molecules. In this study, we have studied the effect of Na-based salts on CAC of aqueous binary mixture of neutral polymer, polyethylene glycol (PEG) and anionic surfactant, sodium dodecyl sulfate (SDS) using viscometric method. To estimate CAC, we have applied Jiang model to the measured viscosity data. From the estimated results, we observe that the value of CAC decreases with the increase of salt molecules in the mixtures. This behavior confirms that the presence of salt molecules favors the binding of SDS molecule to the PEG chain. Bangladesh Journal of Physics, 27(2), 39-48, December 2020

Ultrasmall Superparamagnetic Iron Oxide Nanoparticles Synthesized by Micellar Approach as a Potential Dual-Mode T1-T2 Contrast Agent

Purpose: A micellar approach is used to synthesize Ultrasmall Superparamagnetic Iron Oxide Nanoparticles (USPIONs) with an average diameter of 3.4±0.5 nm, suitable for dual-mode T1-T2 contrast agents. Methods: Micelles with 3.8 nm, measured by dynamic light scattering, were obtained by self-organizing the surfactant iron(III) dodecyl sulfate (IDS) in 1-octanol. IDS was prepared by replac-ing Na+ cation in sodium dodecyl sulfate molecule, and its critical micelle concentration (CMC) was measured by electrical conductivity. The USPIONs were synthesized in a biphasic system: IDS in octanol (55% above the CMC) and water containing NaBH4. Results: A yellow precipitate is immediately formed at the water/alcohol interface, rapidly changes to a black one, and transfers to the aqueous phase. The magnetite phase was confirmed by X-ray diffraction and Mössbauer spectroscopy. The magnetic behavior shows a major paramagnetic char-acter with a weak ferromagnetic component at 5 K, the latter attributed to the interparticle couplings below its blocking temperature (TB = 35 K). The particles were coated with carboxymethyl dextran, showing an isoelectric point of 2.7 with electrokinetic potential around -30 mV in the physiological pH range. Magnetic relaxation measurements showed relaxivity values r1 = 0.17 mM-1 s-1 and r2 = 1.73 mM-1 s-1 (r2/r1 = 10) in a 3T field. These values infer that the ultrasmall size affects the interac-tions with the protons of the nearby water molecules. The r2 value decreases because the core mag-netization decreases with size; r1 intensifies due to the high surface. Conclusion: The results show a system with high colloidal stability, non-cytotoxic, and potential application as T1-T2 dual-mode contrast agents.

Surfactant Adsorption to Gypsum Surfaces and the Effects on Solubility in Aqueous Solutions.

Vibrational sum frequency generation (VSFG) spectroscopy, conductometric titration measurements, and EDX elemental mapping were used to examine surfactant adsorption to the gypsum (010) surface and assess the effects of surfactant adsorption on gypsum solubility in aqueous solutions. Sodium dodecyl sulfate (SDS) and dodecyltrimethylammonium chloride (DTAC) were used as anionic and cationic surfactants, respectively. Gypsum/SDS interactions result in an ordered precipitate layer on the gypsum surface after water evaporation; gypsum/DTAC interaction did not show a similar effect, despite exposure of gypsum to equivalent amounts of surfactant. VSFG spectra showed that SDS molecules adsorb with their chains parallel to the gypsum surface; spectra from gypsum surfaces treated with DTAC, however, showed no measurable response, implying that these surfactants form disorganized aggregates with no polar ordering. Vibrational data were supported by independent EDX measurements that show a uniform distribution of SDS across the gypsum surface. In contrast, element-specific EDX images showed that DTAC clustered in tightly localized patches that left most of the gypsum surface exposed. The uniform adsorption of SDS on the gypsum surface suppresses long-term dissolution up to 40% when compared to samples exposed to DTAC. Gypsum samples in DTAC-containing solutions lose approximately the same amount of material to dissolution as samples immersed in pure water.

Polyamide thin film nanocomposite membrane with internal void structure mediated by silica and SDS for highly permeable reverse-osmosis application

The pursuit of highly permeable thin film nanocomposite (TFNC) membrane is an eternal topic for reverse-osmosis (RO) application. Here, we developed a new avenue based on interfacial polymerization to generate a polyamide TFNC membranes EVOH-SiS-PA by adding silica nanorods (SNRs) and sodium dodecyl sulfate (SDS) in water phase on the surface of EVOH nanofibrous scaffold. The resultant membrane presents a foam-like PA layers with a hierarchical internal voids structure, which is 2–3 μm in thick and distinctly differs to the membranes reported to date. The structure feature can be attributed to the fast reaction between MPD and TMC, Marangoni convection in water phase synergistically determined by SDS molecules on water/hexane interface and SNRs with abundant hydroxyl groups. Comparatively, PA TFNC membranes without SDS and/or SNRs just present a PA layer with smaller thickness (1–2 μm), surface roughness and surface area. As a result, a high permeance of 8.5 L m−2 h−1 bar−1 and a reasonably high rejection to NaCl, CuSO4 and MO feed solution (97.1%–2000 ppm NaCl, 98.2% rejection to 2000 ppm CuSO4 and 99.2% to 20 ppm MO) were obtained towards EVOH-SiS-PA, outperforming the currently reported RO membranes. Here, we provide an approach to fabricate advanced PA TFNC membranes with excellent performance, highlighting their great potential in reverse-osmosis application.

New Design of a Sample Cell for Neutron Reflectometry in Liquid–Liquid Systems and Its Application for Studying Structures at Air–Liquid and Liquid–Liquid Interfaces

Knowledge of interfacial structures in liquid–liquid systems is imperative, especially for improving two-phase biological and chemical reactions. Therefore, we developed a new sample cell for neutron reflectometry (NR), which enables us to observe the layer structure around the interface, and investigated the adsorption behavior of a typical surfactant, sodium dodecyl sulfate (SDS), on the toluene-d8-D2O interface under the new experimental conditions. The new cell was characterized by placing the PTFE frame at the bottom to produce a smooth interface and downsized compared to the conventional cell. The obtained NR profiles were readily analyzable and we determined a slight difference in the SDS adsorption layer structure at the interface between the toluene-d8-D2O and air-D2O systems. This could be owing to the difference in the adsorption behavior of the SDS molecules depending on the interfacial conditions.

Reversible assembly of silica nanoparticles at water-hydrocarbon interfaces controlled by SDS surfactant.

Achieving reversible and tunable assembly of silica nanoparticles at liquid-liquid interfaces is vital for a wide range of scientific and technological applications including sustainable subsurface energy applications, catalysis, drug delivery and material synthesis. In this study, we report the mechanisms controlling the assembly of silica nanoparticles (dia. 50 nm and 100 nm) at water-heptane and water-toluene interfaces using sodium dodecyl sulfate (SDS) surfactant with concentrations ranging from 0.001-0.1 wt% using operando ultrasmall/small-angle X-ray scattering, cryogenic scanning electron microscopy imaging and classical molecular dynamics simulations. The results show that the assembly of silica nanoparticles at water-hydrocarbon interfaces can be tuned by controlling the concentrations of SDS. Silica nanoparticles are found to: (a) dominate the interfaces in the absence of interfacial SDS molecules, (b) coexist with SDS at the interfaces at low surfactant concentration of 0.001 wt% and (c) migrate toward the aqueous phase at a high SDS concentration of 0.1 wt%. Energetic analyses suggest that the van der Waals and electrostatic interactions between silica nanoparticles and SDS surfactants increase with SDS concentration. However, the favorable van der Waals and electrostatic interactions between the silica nanoparticles and toluene or heptane decrease with increasing SDS concentration. As a result, the silica nanoparticles migrate away from the water-hydrocarbon interface and towards bulk water at higher SDS concentrations. These calibrated investigations reveal the mechanistic basis for tuning silica nanoparticle assembly at complex interfaces.

Kaolinite colloidal suspensions under the influence of sodium dodecyl sulfate

Rheological properties of kaolinite particle suspensions in water were studied in the presence of sodium dodecyl sulfate (SDS). The characterization of slightly and strongly sonicated samples revealed the impact of particle initial clustering and agglomeration on their flow behavior; findings revealed that sonicated samples exhibit a stronger network. The influence of kaolinite concentration, sonication, and SDS loading on the apparent slip of kaolinite suspensions was also studied. The presence of SDS molecules prevents particle aggregation and network formation, which leads to a gradual reduction in yield stress. Through a suggested spatial hindrance mechanism, adding SDS above the minimum amount for micelle formation also stops network formation. Finally, it was found that increasing the concentration of kaolinite and sonication reduces the apparent slip, whereas increasing the surfactant concentration increases slip significantly. As a result of shear-induced migration, adding surfactant causes the interface to deplete and thus exhibit apparent slip.

Understanding the interface structures of water-based and solvent-based poly(methyl methacrylate) coatings at the molecular level

Water-based polymer coatings usually exhibit poor adhesion performance compared to their solvent-based counterparts. Unveiling the difference in interface structures between water-based and solvent-based polymer coatings will help to improve the adhesion performance of water-based polymer coatings. Herein, sum frequency generation (SFG) vibrational spectroscopy was utilized to detect the buried interfaces of water-based and solvent-based polymer coatings. Water-based poly(methyl methacrylate) (PMMA) coatings containing sodium dodecyl sulfate (SDS) as an emulsifier and solvent-based PMMA coatings using toluene as solvent were selected as the model systems for this investigation. The results demonstrate that the interface between water-based PMMA and silica substrate is mainly occupied by SDS and water molecules, and the polymer chains show random-coil conformations due to their encapsulation by SDS. In contrast, for the solvent-based PMMA, the PMMA chains directly contact the silica substrate and exhibit stretched chain conformations at the interface. The interface structure of water-based PMMA coatings can be improved by annealing at Tg + 70 ℃ to form an adsorbed polymer layer. This work reveals the origin of the difference in the adhesion strength of water-based and solvent-based polymer coatings at the molecular level, which is significant for the design and performance optimization of water-based polymer coatings.

Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis of Proteins.

Most analytical electrophoreses of proteins are achieved by separation in polyacrylamide gels under conditions that ensure dissociation of proteins into individual polypeptide subunits and minimize aggregation. Most commonly, the anionic detergent sodium dodecyl sulfate (SDS) is used in combination with a reducing agent (β-mercaptoethanol or dithiothreitol) and with heating to dissociate proteins before loading onto the gel. SDS binding denatures the polypeptides and imparts a negative charge that masks their intrinsic charge. The amount of SDS bound is generally sequence-independent and proportional to molecular weight; at saturation, approximately one SDS molecule is bound per two amino acids, or ∼1.4 g of SDS per gram of polypeptide. Therefore, the migration of SDS-polypeptide complexes in an electric field is proportional to the relative size of the polypeptide chain, and its molecular weight can be estimated by comparison to protein markers of known molecular weight. However, hydrophobicity, highly charged sequences, and certain posttranslational modifications such as glycosylation or phosphorylation may also influence migration. Thus, the apparent molecular weight of modified proteins does not always accurately reflect the mass of the polypeptide chain. This protocol describes preparation and running of SDS-PAGE gels, followed by staining to detect proteins using Coomassie Brilliant Blue. Finally, the stained SDS-PAGE gel may be scanned to an image or preserved by drying.

Molecular dynamics study on the effect of surfactant mixture on their packing states in mixed micelles

Mixture of different surfactant molecules possess better performances than single surfactant, which has importantly scientific and practical significance. In this paper, the effects of different mole ratios on the packing states of sodium dodecyl sulfate (SDS) and n-dodecyl betaine (NDB) in mixed micelles are studied through molecular dynamics simulations. The packing state is characterized by calculating and comparing the configuration entropy and entropy decomposition of SDS and NDB. Results show that mixing with NDB molecules can cause the increase of SDS packing order in mixed micelles, while mixing with large proportions of SDS molecules can cause the decrease of NDB packing order in mixed micelles. Moreover, structural properties that are closely related to the packing state are analyzed. The surface hydrophobicity and hydrophilicity of SDS molecules in micelle can be reversed through changing its mole fraction. Both SDS and NDB terminal carbon atoms in mixed micelles possess opposite distribution tendency to those in pure SDS or NDB micelle. As mixed ratio changes, dominant packing patterns of SDS and NDB in mixed micelles are different. Two represent models of mixed micelle with the change of mole ratios are presented.

Cryo-TEM and rheological study on shear-thickening wormlike micelles of zwitterionic/anionic (AHSB/SDS) surfactants

HypothesisShear-thickening micelles were mostly made of cationic surfactants, but shear-thickening was rarely reported in the zwitterionic/anionic surfactants. Since wormlike micelles were essential in shear-thickening systems, it should be common for the hybrid wormlike micelles formed by zwitterionic/anionic surfactants, and their fundamental features need to be clarified. ExperimentsThe micellization of zwitterionic surfactant homologies alkyl dimethyl amidopropyl hydroxyl sulfobetaine (AHSB) and sodium dodecyl sulfate (SDS) in brine was studied, and various environmental factors were considered systematically. Light scattering, rheology, zeta potential, 1H NMR and cryo-TEM techniques were employed to characterize the AHSB/SDS wormlike micelles. FindingsAHSB/SDS hybrid wormlike micelles were formed in a wide xSDS region to endow them with apparent viscosities, in which the electrostatic and hydrophobic interactions between AHSB and SDS molecules were critical. AHSB with the longer tail, the higher cAHSB and cNaCl were advantageous to enhance the viscosity because of the longitudinal growth of wormlike micelles. The shear-thickening AHSB/SDS samples were commonly composed of unbranched wormlike micelles with various length, and the shear-induced alignment of wormlike micelles was the major cause as verified by cryo-TEM. Moreover, the quantitative relationships on the critical shear rate ɣ̇c were established, and the activation energies were obtained from the temperature-dependent ɣ̇c.

Physicochemical nature of sodium dodecyl sulfate interactions with bovine serum albumin revealed by interdisciplinary approaches

To rigorously characterize the interactions of sodium dodecyl sulfate (SDS) with bovine serum albumin (BSA) a set of experimental methods, namely isothermal titration calorimetry, conductometric titration, steady-state fluorescence spectroscopy, differential scanning calorimetry and circular dichroism spectroscopy, supported by in silico analysis have been applied. The influence of pH and temperature on the binding mode has been revealed. At a low molar ratio of SDS to BSA up to ca. 16:1, there are at least two structurally distinct binding sites in BSA. The formation of SDS-BSA complexes is an enthalpy-driven process in which the van der Waals interactions play a crucial role. The first binding site, located close to the Trp-134 residue within the sub-domain IA, is pH-independent and binds two molecules of SDS per one molecule of BSA whereas the total number of SDS molecules bound to the second site of albumin is affected by temperature and pH. The saturation of the first binding site of BSA (ca. 0.009 mg of SDS per 1 mg of BSA) is sufficient to thermally stabilize the helical conformation of BSA. The presented results have important structural and thermodynamic implications to understand the influence of a widely used anionic surfactant on globular protein functionality in modern branches of chemistry.

The Additive Influence of Propane-1,2-Diol on SDS Micellar Structure and Properties.

Micellar systems are colloids with significant properties for pharmaceutical and food applications. They can be used to formulate thermodynamically stable mixtures to solubilize hydrophobic food-related substances. Furthermore, micellar formation is a complex process in which a variety of intermolecular interactions determine the course of formation and most important are the hydrophobic and hydrophilic interactions between surfactant–solvent and solvent–solvent. Glycols are organic compounds that belong to the group of alcohols. Among them, propane-1,2-diol (PG) is a substance commonly used as a food additive or ingredient in many cosmetic and hygiene products. The nature of the additive influences the micellar structure and properties of sodium dodecyl sulfate (SDS). When increasing the mass fraction of propane-1,2-diol in binary mixtures, the c.m.c. values decrease because propane-1,2-diol is a polar solvent, which gives it the ability to form hydrogen bonds, decreasing the cohesivity of water and reducing the dielectric constant of the aqueous phase. The values of are negative in all mixed solvents according to the reduction in solvophobic interactions and increase in electrostatic interaction. With the rising concentration of cosolvent, the equilibrium between cosolvent in bulk solution and in the formed micelles is on the side of micelles, leading to the formation of micelles at a lower concentration with a small change in micellar size. According to the 1H NMR, with the addition of propylene glycol, there is a slight shift of SDS peaks towards lower ppm regions in comparison to the D2O peak. The shift is more evident with the increase in the amount of added propane-1,2-diol in comparison to the NMR spectra of pure SDS. Addition of propane-1,2-diol causes the upfield shift of the protons associated with hydrophilic groups, causing the shielding effect. This signifies that the alcohol is linked with the polar head groups of SDS due to its proximity to the SDS molecules.

Innovative Biotechnology for Generation of Cardiac Tissue

Heart transplantation remains the only curative treatment for end-stage heart failure. This life-saving option continues to be limited by the low number of organ donors, graft rejection and adverse effects of immunosuppressants. Engineering bioartificial hearts from acellular native-derived scaffolds and stem cells has gained attention because of its potential to overcome these limitations. In this study, rat hearts (n = 20) were decellularized by means of coronary perfusion with 1% sodium dodecyl sulfate (SDS) in a modified Langendorff device. The electrical field behavior of the SDS molecule was studied and it was assumed that when applying an alternating current, the exposure time of the tissue to the detergent might decrease. To repopulate the decellularized extracellular matrix (ECM), human mesenchymal stem cells (hMSCs) were used, induced to differentiate into cardiomyocytes (CMs) with 5-azacytidine (5-aza). The results showed no cellular debris and an intact ECM following decellularization. Decellularization in the presence of an electric field proved to be faster, decreasing the potential risk of ECM damage due to the detergent. After cell seeding and culturing of eight scaffolds with hMSCs, the recellularization process was analyzed using optic microscopy (OM), which showed cells suggestive for CMs. This study presents a novel and efficient decellularization protocol using an electric field and suggests that hMSCs can be useful in the generation of a bioartificial heart.

Sol-gel coating filled with SDS-stabilized fullerene nanoparticles for active corrosion protection of the magnesium alloy

Sodium Dodecyl Sulfate (SDS) surfactant was stabilized on the fullerene C60 nanoparticles. The raw, aminated (F-NH 2 ), and SDS-stabilized (F-SDS) fullerene nanoparticles were characterized by Scanning Electron Microscopy (SEM), Fourier-Transform Infrared Spectroscopy (FTIR), Energy Dispersive X-ray Spectroscopy (EDS), and Thermal Gravimetric Analysis (TGA). Then, the functionalized nanoparticles were dispersed inside the sol-gel coating for active corrosion protection of AM60B magnesium alloy . Suitable dispersion of the F-SDS nanoparticles inside the sol-gel coating was confirmed by Transmission Electron Microscopy (TEM). After addition of the F-NH 2 and F-SDS nanoparticles, micrometric defects in the sol-gel coating disappeared. A relative increment in the surface roughness of the coating was observed by Atomic Force Microscopy (AFM) after incorporation of the F-NH 2 and F-SDS nanoparticles. Also, a considerable improvement in the corrosion protection of the sol-gel coating after addition of the F-NH 2 and F-SDS nanoparticles (500 ppm) was shown by Electrochemical Impedance Spectroscopy (EIS) in 3.5 wt% NaCl. Based on the SEM and EDS-mapping analyses at the end of the corrosion tests , the corrosion damages of the F-SDS containing sol-gel coating has been considerably reduced. • SDS molecules were successfully stabilized on the fullerene C60 nanoparticles. • SDS grafted nanoparticles (F-SDS) showed suitable dispersion in sol-gel coating. • The F-SDS containing coating was crack-free, uniform, and thermally resistive. • The F-SDS containing sol-gel film showed the best corrosion protection performance.