Small Diameter Research Articles

An alternative filament fabrication method as the basis for 3D-printing personalized implants from elastic ethylene vinyl acetate copolymer

In this work, a novel tool for small-scale filament production is presented. Unlike traditional methods such as hot melt extrusion (HME), the device (i) allows filament manufacturing from small material amounts as low as three grams, (ii) ensures high diameter stability almost independent of the viscoelastic behavior of the polymer melt, and (iii) enables processing of materials with rheological profiles specifically tailored toward fused filament fabrication (FFF). Hence, novel materials, previously difficult to process due to HME limitations, become easily accessible for FFF for the first time. Here, we showcase the production of highly flexible drug-free, and drug-loaded filaments based on ethylene-vinyl acetate polymers with a vinyl acetate content of 28 w% (EVA28) and unprecedented high melt flow rates of up to 400 g/10 min. Owing to their low viscosity, FFF with low print nozzle sizes of 250 μm was achieved for the first time for EVA28. These small nozzle diameters facilitate 3D-printing of high-resolution structures in small-dimensional dosage forms such as subcutaneous implantable drug delivery systems, which can later be used for personalization. Consequently, the material portfolio for FFF is tremendously broadened, allowing material and formulation optimization toward FFF, independent of a preliminary extrusion process.

Narrow true lumen favors future complication even in small diameter of type B aortic dissection

Narrow true lumen favors future complication even in small diameter of type B aortic dissection

Comparison of Efficacy and Safety of Different Guided Technologies Combined With Ultrathin Bronchoscopic Biopsy for Peripheral Pulmonary Lesions.

Various bronchoscopic guidance techniques have emerged to improve the diagnostic yield of peripheral pulmonary lesions (PPLs), especially when combined with ultra-thin bronchoscopy. However, uncertainties exists in the convenience, accuracy rate, and complications of these techniques. We compared the feasibility, accuracy rate, and complication rates of transbronchial biopsy of PPLs sampled by the standard thin-layer CT navigation combined with ultrathin bronchoscopy (CTNUTB), the Lungpro virtual navigation combined with ultrathin bronchoscopy (VNUTB), and electromagnetic navigation combined with ultrathin bronchoscopy (ENUTB). Retrospectively identified were 256 patients sampled with transbronchial biopsy of PPLs. Eligible patients referred for CTNUTB, VNUTB, and ENUTB from January 2017 to December 2021 were included. We comprehensively compared the accuracy rate, feasibility, and complication rates for each method. There was no significant difference in the accuracy rate of CTNUTB, VNUTB, and ENUTB (p = 0.293). The operation time via Lungpro navigation was the shortest (14.4 min, p < 0.001). The planning time via CT planning was the shortest (7.36 min, p < 0.001). There was no difference in the incidence of complications such as hemorrhage, pneumonia, and pneumothorax (p = 0.123). Besides, ENUTB costs more than $2000, while CTNUTB and VNUTB cost only about $130-230. CTNUTB is still the main bronchoscopy method we recommended, which has low cost, simple operation, and safety no less than the others. In contrast, ENUTB provides a higher accuracy rate for small diameter nodules (less than 2 cm), which has a high use value and is worth promoting in the future.

Experimental study of oil-water two-phase flow patterns in a vertical large diameter pipe

The flow structure and the phase inversion have great influence on the flow measurement in vertical upward oil-water two-phase flow. This paper attempts to investigate the flow patterns in oil-water flows through a vertical upward large pipe with the designed mini-conductance array probes measurement system and the vertical multi-electrode array (VMEA) measurement system. According to the output waveform of the mini-conductance array probes, the oil-in-water flow, transition flow and water-in-oil flow can be identified effectively. The fluctuating signals of the VMEA is processed by the recurrence plot and the time-frequency representation, the results show that the VMEA conductance signal with average measurement characteristics can realize an effective identification of the above three flow patterns, which has a good agreement with the results of the mini-conductance array probes. Finally, via comparing with previous published flow pattern transition boundary models in different pipe diameters, it is founded that the boundary line of the transition to oil-in-water based on the kinematic wave-based model and the observation-based model in the same diameter pipe are consistent with our experimental data. And the pipe diameter affects the flow pattern transition, compared with the boundary in small diameter pipe, the phase inversion requires a larger oil velocity, and the transition zone becomes narrower in large diameter pipe.

The acoustic properties of FDM printed wood/PLA-based composites

The acoustic properties of the Fused Deposition Modelling (FDM) printed PLA wood composite was investigated. Initially tensile and flexural of wood PLA composite was studied with respect to varying layer thickness (0.15 mm, 0.20 mm, and 0.30 mm), infill density (30%, 60%, and 90%), and pattern (Layer, Triangle, and Hexagon). The outcomes demonstrated that the specimen produced with a hexagonal pattern, 90 % infill density, and 0.2 mm layer thickness had the highest tensile (16 MPa) and flexural strength (16 MPa). Utilizing this optimized parameter, micro-perforated panels were printed and acoustic properties were studied. Five specimens with a 3 mm thickness, various perforation diameters (5 mm, 4 mm, and 3 mm), and architecturally tapered perforations were fabricated. Using the impedance tube approach, the sound transmission loss and sound absorption coefficients were measured. The findings indicate that, in comparison to all the printed specimens, tapered type perforation with an exterior diameter of 5 mm and an internal diameter of 4.7 mm showed highest sound absorption coefficient of 0.60 Hz. A viscous loss is obtained by its convergent hole diameter reduction, which results in sound attenuations and is easily absorbed in the micro-perforated panel. Similar to this, the specimen printed with smaller perforation diameters (3 mm) had a high sound transmission loss of 79 dB. The small diameter of the perforations prevented the passage of sound waves. The current study is anticipated to lay the groundwork for extensive future research on these classes of materials, potentially serving as a catalyst for advancements in FDM based polymeric materials research and development.

Calibration and Experimental Verification of Finite Element Parameters for Alfalfa Conditioning Model

Conditioning is an important step in harvesting alfalfa hay, as squeezing and bending alfalfa stems can break down the stem fibers and accelerate the drying rate of alfalfa. The quality of alfalfa hay is directly affected by the conditioning effect. The finite element method (FEM) can quantitatively analyze the interaction relationship between alfalfa and conditioning rollers, which is of great significance for improving conditioning effects and optimizing conditioning systems. The accuracy of material engineering parameters directly affects the simulation results. Due to the small diameter and thin stem wall of alfalfa, some of its material parameters are difficult to measure or have low measurement accuracy. Based on this background, this study proposed a method for calibrating the finite element parameters of thin-walled plant stems. By conducting radial tensile, shear, bending, and radial compression tests on alfalfa stems and combining with the constitutive relationship of the material, the range of engineering parameters for the stems was preliminarily obtained. By conducting a Plackett–Burman experiment, the parameters that affect the maximum shearing force of stems were determined, including Poisson’s ratio in the isotropic plane, radial elastic modulus, and the sliding friction coefficient between the alfalfa stem and steel plate. By conducting the steepest ascent experiment and Box–Behnken experiment, the optimal values of Poisson’s ratio, radial elastic modulus, and sliding friction coefficient were obtained to be 0.42, 28.66 MPa, and 0.60, respectively. Finally, the double-shear experiment, radial compression experiment, and conditioning experiment were used to evaluate the accuracy of the parameters. The results showed that the average relative error between the maximum shear and the measured value was 0.88%, and the average relative error between the maximum radial contact force and the measured value was 2.13%. In the conditioning experiment, the load curve showed the same trend as the measured curve, and the simulation results could demonstrate the stress process and failure mode of alfalfa stems. The modeling and calibration method can effectively predict the stress and failure of alfalfa during conditioning.

Crop Improvement of Moringa oleifera L. through Genotype Screening for the Development of Clonal Propagation Techniques of High-Yielding Clones in Malaysia.

Moringa oleifera L. is a valuable multipurpose tree species widely planted for centuries due to its high medicinal value and antifungal, antiviral, antidepressant, and anti-inflammatory properties in the food industry. However, its cultivation is hindered by production constraints such as the unavailability of planting material and the inadequate number of high-yielding clones. Thus, a study was initiated to select high-yielding clones in terms of growth and chemical content for the mass propagation of superior moringa trees. Screening on high-yielding clones with high astragalin content was conducted through the high-performance liquid chromatography (HPLC) analysis of moringa leaf extract. Selected genotypes were evaluated for their anti-inflammatory potential through in vitro bioactivity assays of leaf methanol extract. The effects of the rooting hormone, rooting substrates, and size of the cutting on the rooting response of branch cuttings of moringa were investigated. Results found that samples collected from different ecological zones of Peninsular Malaysia show significant variation in terms of astragalin content. The extracts were observed to show considerable variation in biological activity against the pro-inflammatory enzymes. The size of the cuttings had significant effects on the rooting of the cuttings as longer cuttings with bigger diameters rooted better than shorter cuttings with smaller diameters. Several genotypes of M. oleifera with superior phenotypic characteristics and bioactive compounds have been identified. Factors affecting the rooting efficiency and optimal conditions of rooting are suggested, which provides valuable information for the propagation of the superior planting material of moringa. This effort will ensure the sustainable production and supply of good quality raw materials for the production of quality end-products for the food and pharmaceutical industry.

Heat transfer augmentation by using different techniques in small scale channels: A review study

In this paper highlights the most significant recent developments in scientific study on Heat sinks are thermal management components made of materials with sufficient thermal conductivity qualities. Due to the increase in operating power and speed as well as the general reduction in system size, the issues of heat removal and temperature management have taken on increasing importance in these studies. Changing the geometry of extended surfaces, the material from which they were made, the working fluid that ran over them and or the dimension of the channel, are some of the subcategories in which studies have been conducted. The current review addresses the main recent findings in the forced convection heat transfer happened at laminar flow inside small scale diameters channels. The recent studies indicated a remarkable enhancement with the change of Re, D and internal geometry of channel. The configuration of flow passages also adopted as a different passive technique to enhance thermal fluid flow.

Experimental Study on the Time-Dependent Resistance of Open-Ended Steel Piles in Sand

Open-ended steel piles are commonly used as the foundation for offshore structures. Numerous model and field tests have demonstrated a time-dependent increase in the resistance of these piles, a phenomenon referred to as pile ageing or pile setup. Additionally, for open-ended steel piles with comparably small diameters, soil plugging enhances the resistance against axial compressive loads. Realistically predicting these effects is necessary for their reliable incorporation into design practice. This contribution presents static compression and tension pile load testing conducted in an experimental pit filled with wet, uniformly graded silica sand. In total, twelve piles (L= 5.5 m, Do= 325 mm) were driven into homogeneously compacted sand using a pneumatic impact hammer. Firstly, static compression pile load testing was executed at various times after installation. Subsequently, static tension pile load tests were carried out. The results of the static compression pile load tests indicate that the compressive resistance doubles over an ageing period of 64 weeks. The experimental investigations of the effect of soil plugging showed marginal soil plugging during pile installation, but a significant influence of the soil plug on the compressive resistance.

Adoption of self-exothermic reaction for synthesis of multifunctional carbon quantum dots: Applications to vincristine sensing and cell imaging

This work introduces an extremely easy method for preparing luminescent carbon dots (CDs) at ambient temperature using 1,2-naphthoquinone sulphonate and ethylenediamine as precursors via self-exothermic reaction without energy input. The as-obtained CDs have a high quantum yield (34.1 %), a production yield of 21.2 %, and a small size diameter (3.44 nm). Various techniques (NMR, TEM, EDX-mapping, XPS, XRD, FT-IR, fluorescence, and UV–visible spectroscopy) were used to characterize the prepared CDs. The CDs exhibited an excitation-independent emission with λex of 275 nm, demonstrating their homogeneity and high purity. The anticancer drug vincristine (VCR) quantitively quenched the fluorescent signal of the synthesized CDs, allowing their application as the first fluorescent nano-sensor to determine VCR. The quenching effect was linear within the range of 0.2–5.0 μg mL−1, enabling the determination of VCR in vials, plasma, and for content uniformity testing with a detection limit of 0.06 μg mL−1. Moreover, the synthesized CDs were employed as a bio-sensing platform to detect VCR in cancer cells owing to their good selectivity, excellent biocompatibility, minimal cytotoxicity, and high stability. The fabrication of CDs with excellent properties at room temperature under mild conditions paves the way for new advancements in the room temperature synthesis of CDs and offers a highly efficient alternative to traditional synthesis approaches.

Understanding the Size‐Dependent Photostability and Photoluminescence Intermittency of Blue‐Emitting Core/Graded Alloy/Shell “giant”‐Quantum Dots

AbstractRecently, giant quantum dots (g‐QDs) with a core/interface graded alloy shell/shell structure have shown promise in reducing photoluminescence (PL) intermittency and improving photostability. However, this approach has been mainly demonstrated with red and green emitting g‐QDs but the blue‐emitting graded alloy QDs has remained less explored. To tackle this challenge, a composition gradient method is employed to create three blue‐emitting CdZnS/CdxZn1–xS/ZnS core/interface graded alloy shell/shell (C/A/S) quantum dots (QDs) with different diameters. The sample with the largest diameter (gQD‐3) exhibits superior optical characteristics, with a photoluminescence quantum yield (PLQY) of approximately 62% and around 80% ON/radiative events at the single‐particle level. Conversely, the smallest diameter (gQD‐1) sample shows lower PLQY and only 30% radiative events with longer OFF/nonradiative events. Probability distribution analysis of PL trajectories, fitted with a truncated power law, reveals a significantly higher carrier de‐trapping rate in gQD‐3 compared to gQD‐1, attributed to its proximity to band edge trap states. Additionally, the largest diameter sample retains remarkable optical performance during 48 h of continuous UV irradiation in colloidal suspension and single‐particle levels. These findings show optimized core/shell structures, gradual alloy interfaces, and outer shell coatings can stabilize blue‐emitting quantum dots, advancing next‐gen optoelectronics.

Optimization of mechanical properties of small diameter artificial blood vessels based on alginate/chitosan/gelatin

Due to the rise in cardiovascular disease and the problem of autologous transplant limitation, the emergence of 3D bioprinted blood vessels using natural polymer materials as ink is becoming increasingly important in the field of small-diameter artificial blood vessels (φ ≤ 6 mm). In this paper, gelatin was firstly adopted to explore alginate/chitosan composite hydrogel properties and solve the current issues of poor mechanical performance and suboptimal printability of small-diameter blood vessels, which indicated that the modification caused a 17.7 % increase in compressive strength and a 63.2 % enhancement in tensile properties. The material microstructure evaluation showed that the samples with gelatin(4 %) presented the excellent water absorption rate(>90 %) significantly increasing their porosities. A self-developed 3D bioprinter was utilized to clarify the controllable mechanism of small-diameter artificial blood vessel, which has superior performance and excellent printability. This study provides a new reference solution to the current challenges in the bio-ink performance and printability of small-diameter artificial blood vessels.

Fabrication of 3D Bioactive Melt Electrowriting Composite Scaffold with High Osteogenic Potential

A key challenge in using melt electrowriting (MEW) technology is incorporating large amounts of bioactive inorganic materials, such as hydroxyapatite (HA). In the present study, following optimization of the fabrication parameters, 40%-HA (HA40) nanoparticles were pre-mixed into medical-grade polycaprolactone (PCL) and processed using the MEW (MEW) technique to mimic the structure and function of the natural extracellular matrix (ECM) for bone regeneration. The HA40 fibrous composite scaffolds showed continuous writing and obtained a well-connected and orderly stacked fibre with a small diameter size (67 ± 8.5µm). A major result of the present study was the successful enrichment and accumulation of the HA particles, which mostly occurred on the MEW fibre external surfaces. This design allows for direct interfacial interaction with human periodontal ligament cells (hPDLCs). We systematically investigated the behaviour and function of hPDLCs on the HA40 composite scaffold, alongside parameters related to mineralization. The HA40 scaffold demonstrated significantly higher metabolic activity and enhanced expression of osteonectin and RUNX2 compared to PCL-only scaffolds, as well as increased levels of ALP and COL1. The study’s findings demonstrate that bioactive composite scaffolds, incorporating 40% HA into m-PCL via MEW, effectively enhance the biological response of the ECM and are promising for potential applications in bone regeneration.

Structure-Mechanical Property Relationships in Carbon Nanotube Yarns

Carbon nanotube (CNT) is an innovative material with significant potential for a wide range of applications, including but not limited to the development of lightweight composite materials or superconductors. A single CNT demonstrates an exceptional degree of tensile strength. CNTs are commonly employed in a structure of yarn, wherein several CNT strands are arranged and aligned together. CNT yarns, on the other hand, have a lower tensile strength than individual CNTs due to the different parameters of the yarn. This study aimed to investigate the effect of different structural parameters on the mechanical properties of CNT yarn. Sixty CNT yarn models with different structures were simulated with the molecular dynamic (MD) simulation. The varied parameters are the chirality of the CNTs, CNTs’ inner diameter, number of walls, crosslink density, and yarn twist angle. Tensile strength results from the simulations were compared concerning the varied parameters, and their influence on the nominal tensile strength of the CNT yarn was studied. It was found that the parameters for the CNT yarn that yields a higher tensile strength are the armchair type CNT with a small diameter, a large number of walls, crosslink density higher than approximately 1%, and a low twist angle.

Experimental study on the influence factors of falling film heat transfer characteristics outside different types of horizontal tubes

An experimental setup was established to analyze the performance of a spiral wound heat exchanger applied to natural gas liquefaction. The boiling behavior of subcooled flow over a small diameter, non-round, horizontal tube was investigated using n-pentane as the working fluid. The effects of flow rate, heat flux, fluid inlet temperature and tube spacing on heat transfer performance were investigated. Based on the experimental conditions of this study, the results indicate that: (1) raising the Reynolds number can effectively enhance the heat transfer coefficient; (2) the increasing in heat flux also has a positive impact on heat transfer performance, but the extent of which is related to the Reynolds number; (3) increasing the tube spacing resulted in higher heat transfer coefficients; (4) under the same working conditions, the heat transfer performance of non-round tubes is higher than that of round tubes; (5) correlation equations were developed to calculate the Nu for smooth, round, elliptical, and egg-shaped tubes. The predictions made by these correlation equations deviated by less than 10 % from the experimental results for the entirety of the experimental conditions.

Comparative experimental and numerical study of mixing efficiency in 3D-printed microfluidic droplet generators: T junction, cross junction, and asymmetric junctions with varying angles

In droplet-based microfluidics, rapid mixing during droplet formation enhances reaction uniformity, eliminating the need for micromixers. In this research, we conducted a comprehensive study by first employing a series of two-dimensional (2D) numerical simulations, followed by experimental investigations using 3D-printed microfluidic chips. We compared the mixing efficiency, droplet diameter, and droplet eccentricity of three different types of droplet generators: T junction, cross junction, and asymmetric droplet generators with various angles. Regarding mixing efficiency, we observed that the asymmetric droplet generators outperformed the cross junction by 30 % but fell slightly short of the mixing efficiency achieved by the T junction (1 %). Additionally, while the mixing index in the asymmetric generators closely matched that of the T junction, these asymmetric generators produced smaller droplets by 72 %. Increasing the angle in asymmetric droplet generators resulted in enhanced mixing efficiencies and an increase in droplet diameters. The asymmetric junction with a 30° angle could achieve a mixing efficiency of up to 80 %. Additionally, an analysis of the dispersed phase flow rate revealed that higher flow rates lead to larger droplet sizes and reduced mixing efficiencies. The asymmetric droplet generators improve mixing efficiency facilitating rapid reagent mixing, all while maintaining a small droplet diameter.

A multi-objective method for large multi-lane roundabout design through microscopic traffic simulation and SSAM analysis

Urban traffic congestion poses a significant challenge, impacting both economic efficiency and environmental sustainability. Roundabouts, recognized for their ability to improve traffic flow and reduce collisions, have become a focal point in traffic management strategies in urban areas. Different types and sizes of single and multi-lane roundabouts can be used, including conventional and innovative roundabouts with small, medium or large size diameters. Many optimization models are available for designing conventional roundabouts but not large roundabouts. To partially cover this gap, the present paper introduces a novel approach integrating simulation-based analysis with a goal programming method to optimize large roundabout design. By leveraging advanced traffic simulation tools like AIMSUN Next and Surrogate Safety Assessment Models (SSAMs), this methodology evaluates multiple design scenarios to enhance traffic flow, safety, and environmental performance. A case study of a complex large roundabout in the Italian greenest and sustainable city demonstrates the efficacy of this methodological approach. The findings provide valuable insights for traffic and highway engineers, emphasizing a data-driven, holistic approach to sustainable traffic management and roundabout optimization.

Latest Findings on the Effects of Gold Nanoparticles on the Storage Quality of Blood Products (2011-2022) - A Narrative Review

Abstract: A wide range of challenges are faced during the storage of blood products, including storage lesions, contamination that must be removed, and cell and protein damage due to chemicals and UV exposure. The enhancement of stability exhibited by gold nanoparticles (GNPs) is a notable advantage of these nanoparticles for the storage of blood products. The results of our review of articles from 2011 to 2022 discussing the effect of GNPs on blood products revealed that in RBCs, the dose, concentration, amount, and surface charge of GNPs significantly affect their compatibility. Purified GNPs were compatible with RBCs. Negatively charged GNPs with smaller diameters at lower concentrations were more compatible. However, in the plasma product, the nanoparticle surface modification with different agents showed greater compatibility. PEGylated nanospheres and GNPs exhibited higher albumin conformational stability than those coated with cetyltrimethylammonium bromide and rods. In the platelet product, smaller GNPs and high GNP concentrations induce platelet aggregation. PEGylation increased the platelet compatibility of GNP. The combination of GNPs with human fibrinogen and clopidogrel prevented clot formation. Finally, the findings of this investigation demonstrate that GNPs are contingent on their surface charge, dosage, and concentration.

Slow depolarizing electrical stimuli reveal differential time courses of nociceptor recovery after prolonged topical capsaicin in human skin

AbstractBackgroundWe examined de‐functionalization and temporal functional recovery of C‐nociceptor evoked pain after topical 8% capsaicin applied for 4 consecutive days.MethodsCapsaicin and placebo patches were applied to human forearm skin (n = 14). Cold, warmth and heat pain thresholds, pain NRS to electrical and thermal (48°C, 5 s) stimuli and axon reflex flare were recorded weekly for 49 days. Mechanical and heat sensitive (‘polymodal’) nociceptors were activated by single electrical half‐period sinusoidal pulses (0.5 s, 1 Hz). Mechanical and heat insensitive (‘silent’) nociceptors were activated by 4 Hz sinusoidal stimuli.ResultsCapsaicin abolished heat pain. Sensation to electrical sinusoidal stimulation was reduced but never abolished during the treatment. Pain to electrical 1 Hz ‘polymodal’ nociceptor stimulation took longer to recover than pain ratings to 4 Hz 2.5 s sinusoidal stimulation activating ‘polymodal’ and ‘silent’ nociceptors (35 vs. 21 days). Heat pain was indifferent to placebo from day 21–49. Axon reflex flare was abolished during capsaicin and only recovered to ~50% even after 49 days.ConclusionsCapsaicin abolishes heat transduction at terminal nociceptive endings, whereas small‐diameter axons sensitive to sinusoidal electrical stimulation can still be activated. 1 Hz depolarizing stimuli evoke burst discharges, as demonstrated before, and recover slower after capsaicin than single pulses induced by 4 Hz. The difference in recovery suggests differential time course of functional regeneration for C‐nociceptor sub‐types after capsaicin. All sensations recovered completely within 7 weeks in healthy subjects. Our findings contrast analgesia lasting for months in spontaneous neuropathic pain patients treated with 8% capsaicin.SignificanceSinusoidal electrical stimulation can still activate small diameter axons desensitized to heat after 4 consecutive days of topical 8% capsaicin application and reveals differential temporal functional regeneration of C‐nociceptor sub‐types. Electrical sinusoidal stimulation may detect such axons that no longer respond to heat stimuli in neuropathic skin.

Design and Experimentation of Small Potato Harvester for Heavy Soil in Hilly and Mountainous Areas

At present, the potato’s mechanized harvesting rate in hilly and mountainous areas is very low. The reasons for this are that in heavy soil, the separation of potato rhizomes from soil or vines is not sufficient, harvesting machinery is seriously damaged by the potato epidermis, and the harvested potato is easily buried in soil, resulting in a missed harvest. In this paper, a two-stage cleaning potato harvester with wave-type and roller-group-type separating mechanisms was designed, and its overall structure and working principle are introduced in detail. The new cleaning mechanism can increase the effective separating length and effective contact area of the potato–soil mixture so as to achieve the purpose of removing clay and heavy soil. The main separator uses a structure that combines offset waves with opposite waves and a staggered arrangement of large–small diameter straight bars. The secondary separator adopts a device combining left-hand and right-hand separating rollers. The discrete element model of the whole machine was established, and the results of the theoretical analysis were verified by simulation. The key factors affecting the harvest quality were analyzed by variance analysis and response surface analysis, and the field experiment was carried out with the rate of clean potatoes, damaged potatoes, and peeled potatoes harvested as the indexes. The field experiments showed that the machine achieved a rate of photos on or out of the earth of 98.87%, a damaged potato rate of 0.91%, and a peeled potato rate of 1.13%. The research results provide theoretical support and a technical reference for the design and optimization of potato harvesters, as well as the improvement of the potato–soil separating efficiency and harvest quality.