SESSION TITLE: Critical Care 2 SESSION TYPE: Affiliate Case Report Poster PRESENTED ON: Tuesday, October 31, 2017 at 01:30 PM - 02:30 PM INTRODUCTION: Horner's syndrome manifests in varying degrees of ptosis, miosis, and anhidrosis. Etiology can vary from central lesions, intracranial tumors and strokes, to peripheral causes, such as carotid artery dissections, pancoast tumors, blunt trauma or iatrogenic injuries. Tracheobronchial injury secondary to intubation is a rare complication, occurring in 0.005% of intubations1. We report a case of Horner's syndrome in an intubated patient due to a tracheal tear. CASE PRESENTATION: A 34 year old woman presented to the emergency department with dyspnea. She was febrile, tachycardic, tachypnic and became hypotensive requiring intubation and vasopressors with a diagnosis of septic shock due to pneumonia. On volume assist control ventilation with a positive end expiratory pressure of 10 cm H2O, her PaO2 to FiO2 ratio was 135. Chest x-ray showed bilateral alveolar infiltrates consistent with acute respiratory distress syndrome; treatment included lung protective ventilation and paralysis. She was positive for influenza A and her urine antigen was positive for Streptococcus pneumoniae, however, tracheal cultures from the day of admission grew only Staphylococcus aureus. She received appropriate antibiotics and oseltamivir. On hospital day 9, she was found to have a pneumothorax and a chest tube was placed. That evening, new onset, unilateral right pupil dilation prompted a CT scan of both the head and neck. The CT revealed a linear laceration of the trachea and air extending into the posterior mediastinum (Figures 1 and 2) and superiorly along the carotids. Bronchoscopy revealed a small anterior tracheal tear. The endotracheal tube was advanced beyond the tear and ventilator settings were changed to minimize ventilator pressures. A subsequent bronchoscopy revealed resolution of the tracheal tear. DISCUSSION: We believe that the increased intrathoracic pressure from free air compressed neurons in the sympathetic chain resulting in Horner’s syndrome. Several reported cases demonstrate Horner's syndrome as a complication of pneumomediastinum. Chipman et al, reported an alcoholic patient who presented with right sided ptosis and miosis and was subsequently found to have significant pneumomediastinum stemming from alveolar rupture in the setting of severe retching2. CONCLUSIONS: The development of Horner's syndrome due to tracheal rupture in an intubated patient is a rare finding. In critically ill patients, as here, it may be possible to treat the laceration with conservative, non-procedural management. Reference #1: Management of iatrogenic tracheobronchial injuries: a retrospective analysis of 29 cases. Schneider et al. Ann Thorac Surg. 2007 Jun;83(6):1960-4. Reference #2: Unilateral ptosis and miosis caused by pneumomediastinum Chipman et al. Neurology 2007;68;1155 DISCLOSURE: The following authors have nothing to disclose: Shivdeep Deo, Michael Vest, David Manoff, Michael Sneider, Alberto Iaia, Timothy Roedder No Product/Research Disclosure Information
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