Slide Surface Research Articles

An Improved Dynamic Surface Sliding Mode Method for Autonomous Cooperative Formation Control of Underactuated USVS with Complex Marine Environment Disturbances

Abstract In this paper, a novel dynamic surface sliding mode control (DSSMC) method, combined with a lateral velocity tracking differentiator (LVTD), is proposed for the cooperative formation control of underactuated unmanned surface vehicles (USVs) exposed to complex marine environment disturbances. Firstly, in view of the kinematic and dynamic models of USVs and the design idea of a virtual control law in a backstepping approach, the trajectory tracking control problem of USVs’ cooperative formation is transformed into a stabilisation problem of the virtual control law of longitudinal and lateral velocities. Then, aiming at the problem of differential explosion caused by repeated derivation in the process of backstepping design, the first-order low-pass filter about the virtual longitudinal velocity and intermediate state quantity of position is constructed to replace differential calculations during the design of the control law, respectively. In order to reduce the steady-state error when stabilising the virtual lateral velocity control law, the integral term is introduced into the design of the sliding mode surface with a lateral velocity error, and then the second-order sliding mode surface with an integral is structured. In addition, due to the problem of controller oscillation and the role of the tracking differentiator (TD) in active disturbance rejection control (ADRC), the LVTD is designed to smooth the state quantity of lateral velocity. Subsequently, based on the dynamic model of USV under complex marine environment disturbances, the nonlinear disturbance observer is designed to observe the disturbances and compensate the control law. Finally, the whole cooperative formation system is proved to be uniformly and ultimately bounded, according to the Lyapunov stability theory, and the stability and validity of the method is also verified by the simulation results.

A Novel Methodology for Detecting Variations in Cell Surface Antigens Using Cell-Tearing by Optical Tweezers.

The quantitative analysis of cell surface antigens has attracted increasing attention due to the antigenic variation recognition that can facilitate early diagnoses. This paper presents a novel methodology based on the optical “cell-tearing” and the especially proposed “dilution regulations” to detect variations in cell surface antigens. The cell attaches to the corresponding antibody-coated slide surface. Then, the cell-binding firmness between a single cell and the functionalized surface is assayed by optically tearing using gradually reduced laser powers incorporated with serial antibody dilutions. Groups B and B3 of red blood cells (RBCs) were selected as the experiment subject. The results indicate that a higher dilution called for lower power to tear off the cell binding. According to the proposed relative-quantitative analysis theory, antigenic variation can be intuitively estimated by comparing the maximum allowable dilution folds. The estimation result shows good consistency with the finding in the literature. This study suggests a novel methodology for examining the variation in cell surface antigens, expected to be widely capable with potential sensor applications not only in biochemistry and biophysics, but also in the micro-/nano- engineering field.

Using a Novel Floating Grinding Process to Improve the Surface Roughness Parameter of a Magnetic Head.

This work concentrated on the improvement of the surface roughness of a magnetic head, through the use of an ultrafine nanodiamond slurry, and a novel floating grinding process, which optimize different experimental factors required for the fine grinding of a magnetic head. The preparation of the grinding plate was confirmed by the observation of the surface change, depth detection, and flatness after ultrafine nanodiamonds were embedded into it by a Keyence high-power microscope at a 20 K magnification. The flatness was measured by a TOTO instrument. The optimum conditions were found to be a pit ratio reach of 30:70 and a plate flatness (average) of 1.8 μm. The rotation speed and vibration frequency were 0.3 and 10 rpm, respectively, for the grinding process. The morphology, size, and elemental composition of blackspots were investigated by SEM, AES, AFM, and transmission electron microscopy (TEM) analysis, which showed that the diameter of the diamonds in the slurry was important for grinding surface improvement. A novel method was proposed in this study to fine grind a magnetic head using a small-sized diamond slurry (100 nm) in conjunction with a novel float lapping method. Comparison experiments were performed under both normal conditions and improved conditions. The results show that by using the novel float lapping method with a small-sized diamond slurry, the minimum roughness was obtained. The finest roughness obtained for the slider surface reached 0.165 nm without blackspots or scratches.

Effects of Ethyl Lauroyl Arginate (LAE) on Biofilm Detachment: Shear Rate, Concentration, and Dosing Time

Biofilm formation is one of the main obstacles in membrane treatment. The non-oxidizing biocide ethyl lauroyl arginate (LAE) is promising for mitigating biofilm development on membrane surfaces. However, the operating conditions of LAE and their impact on biofilm detachment are not comprehensively understood. In this study, a real-time in vitro flow cell system was utilized to observe biofilm dispersal caused by the shear rate, concentration, and treatment time of LAE. This confirmed that the biofilm was significantly reduced to 68.2% at a shear rate of 3.42 s−1 due to the increased physical lifting force. LAE exhibited two different mechanisms for bacterial inactivation and biofilm dispersal. Biofilms treated with LAE at sub-growth inhibitory concentrations for a longer time could effectively detach the biofilm formed on the surface of the glass slides, which can be attributed to the increased motility of microorganisms. However, a high concentration (i.e., bactericidal concentration) of LAE should be seriously considered because of the inactivated sessile bacteria and their residual debris remaining on the surface. This study sheds light on the effect of LAE on biofilm detachment and provides insights into biofouling mitigation during the membrane process.

Pairwise control in swarm flocking with application to UAVs

We propose a pairwise cooperative mode and control method to perform short-range cooperative missions of two specific UAVs in a swarm. The pair of UAVs can converge simultaneously to a specified distance and keep flocking with others. For pairwise control, we propose a new sliding mode control architecture including “Quadratic Error Sliding Surface” and “Sliding Mode Sign Multiplier”, which have the advantages of simple parameter design, high precision, and anti-disturbance ability. The proposed sliding surface is reachable, and the controller is stability which is proved based on the Lyapunov stability theory. Finally, to verify the influence of the pairwise control effect in swarm flight, simulations were carried out with a different number of UAVs based on the quadrotor nonlinear dynamic model. Compared with the classical control method, the simulations demonstrate the superiority in control accuracy.

The concept of tectonic provenance: Case study of the gigantic Markagunt gravity slide basal layer

AbstractFormation and evolution of the basal layer in large landslides has important implications for processes that reduce frictional resistance to sliding. In this report, we show that zircon geochronology and tectonic provenance can be used to investigate the basal layer of the gigantic‐scale Markagunt gravity slide of Utah, USA. Basal layer and clastic injectite samples have unique tectonic chronofacies that identify the rock units that were broken down during emplacement. Our results show that basal material from sites on the former land surface is statistically indistinguishable and formed primarily by the breakdown of upper plate lithologies during sliding. Decapitated injectites have a different tectonic chronofacies than the local basal layer, with more abundant lower plate‐derived zircons. This suggests clastic dikes formed earlier in the translation history from a structurally deeper portion of the slide surface and a compositionally different basal layer before being translated to their current position.

Abnormal wetting dynamics of Silwet-laden droplets on partially wetting substrates

Silwet L-77 surfactant has the unique ability to spread water droplets across surfaces to a greater extent than conventional surfactants within a second. By using Silwet, the N,N-dimethylformamide (DMF) droplets can exhibit self-propulsion on a glass substrate. The peculiar wetting dynamics of the Silwet-laden DMF droplets was explored on the partially wetting substrates, including the polytetrafluoroethylene slide and slippery liquid-infused porous surface with negligible contact angle hysteresis (CAH). The time evolution of the contact angle (CA) was monitored for both high and low Silwet concentrations. Moreover, the volume inflation/deflation method and inclined plane method were employed to investigate the CA relaxation. The sessile droplet exhibits long-time wetting dynamics and it spreads very slowly, depending on the Silwet concentration. The dynamic CA decreases for more than 20 min at low Silwet concentrations (e.g., 1 wt%), but the droplet reaches its equilibrium state within 4 min at high concentrations (e.g., 10 wt%). The relaxation behavior is also influenced significantly by CAH which is found to impede the initial CA relaxation. Finally, the abnormal wetting dynamics is explained by the time-varying interfacial tensions according to Young’s equation.

Sliding Mode Control of Manipulator Based on Improved Reaching Law and Sliding Surface

Aiming at the problem of convergence speed and chattering in sliding mode variable structure control of manipulator, an improved exponential reaching law and nonlinear sliding surface are proposed, and the Lyapunov function is used to analyze its stability. According to the dynamic model of the 6-DOF UR5 manipulator and the proposed reaching law and sliding surface, the corresponding control scheme is designed. The control performance of the proposed control scheme is verified by tracking the end trajectory of the manipulator on the MATLAB and CoppeliaSim robot simulation platform. The experimental results show that the proposed control scheme can not only significantly improve the convergence speed and make the system converge quickly, but also can effectively reduce the chattering of the system. Even in the presence of disturbance signals, fast and stable tracking can be achieved while ensuring the robustness of the system, and the chattering of the robotic arm system can be weakened to a certain extent. Compared with the classical control method based on the computational torque method and the traditional sliding mode control scheme based on the exponential reaching law, the proposed scheme has certain advantages in terms of tracking accuracy, convergence speed, and reducing system chattering, and effectively improves the overall control performance of the system.

Lactobacillus spp. derived biosurfactants effect on expression of genes involved in Proteus mirabilis biofilm formation.

Nosocomial infections (NIs) have been defined as infections ocuurring shortly after hospitalization or discharging from the hospital. It is associated with increased morbidities and mortalities. Proteus mirabilis considered as the hospital-acquired pathogen. The purpose of this study was to investigate the effect of Lactobacillus acidophilus-derived biosurfactant on P. mirabilis biofilm formation and flhDC/rsmA expression level (P. mirabilis standard strain ATCC 7002 and urinary infection isolated P. mirabilis strains). One of the potential strategies for the prevention of nosocomial infections is the use of probiotics. L. acidophilus was selected as a probiotic strain to produce biosurfactants. A biosurfactant reduces the adhesion of strains to microtiter plate and glass slide surfaces due to the reduction of surface tension. By using Real time PCR quantitation method we showed that biosurfactant significantly reduced rsmA expression whereas increased flhDC expression in P. mirabilis isolates. Several properties of P. mirabilis cells (biofilm formation, adhesion, and gene expression) were changed after L. acidophilus- derived biosurfactant treatment. In this study we showed that biosurfacant treatment can pave the way for a possible control of biofilm development. Based on our findings, we suggest that the prepared biosurfactant may interfere with adhesion of P. mirabilis to catheters and other devices.

Nonlinear homogeneous sliding mode approach for fixed-time robust formation tracking control of networked quadrotors

A formation flight control algorithm for a multi-agent system composed of a group of perturbated quadrotors is thoroughly investigated in this paper. Both theoretical and practical aspects are addressed in detail to design and implement the control algorithm in a distributed fashion among the networked agents. By adopting the sliding mode framework: (i) A novel Nonlinear Homogeneous Nonsingular Terminal Sliding Surface (NHNTSS) is designed. To ensure Global Asymptotic Stability (GAS) as well as fixed-time convergence of the states, the sliding surface design skillfully employs the generalized weighted homogeneity theory. (ii) A novel Distributed Fixed-Time Continuous Nonsingular Control Protocol (DFCNCP) is proposed for the position-loop of each quadrotor agent by utilizing the designed NHNTSS. Moreover, the control scheme comprises a disturbance observer to compensate for the lumped disturbances affecting the position dynamics and estimate the unmeasurable linear velocities of the quadrotors. Overall, the synthesized controller can drive the formation tracking errors into close vicinity of the origin in fixed-time uniformly to the values of the Initial Conditions (ICs), i.e., initial positions of the quadrotors in the 3D state-space. The mathematical proofs based on the bi-limit approximation in the existing related works can only indicate that the system is guaranteed to be fixed-time stable without any estimation of the settling (convergence) time. In contrast, rigorous stability analyses are conducted in the present work by virtue of algebraic Lyapunov tools, i.e., Algebraic Lyapunov Equation (ALE) and Lyapunov Quadratic Function (LQF). Thus, an expression of the upper-bound on the settling-time is given explicitly. Numerical simulations and real experiments in the form of exhaustive comparative studies are carried out to validate the findings of this research work. Overall, the obtained results confirm the superiority of the proposed control strategy in terms of uniform fast fixed-time convergence, strong disturbance rejection, chattering alleviation, and control precision.

SPH Modelling of a Dike Failure with Detection of the Landslide Sliding Surface and Damage Scenarios for an Electricity Pylon

The 3D SPH code SPHERA (RSE SpA) simulates the triggering and runout stages of a full-scale earth-filled dike failure with coastal flood. The code formulation is consistent with the Kinetic Theory of Granular Flow KTGF and requires no tuned input. The main Landslide Sliding Surface LSS within the dike is detected from the field of the quadratic invariant of the strain-rate tensor. The comparison with the experimental LSS position shows Maximum Gross Errors of 0.90m, in terms of depth difference at fixed planimetric point, and of 0.41m, in terms of LSS distance (i.e. 22% and 10% of the initial dike-top height over the excavation bottom). Inter-comparisons consider calibrated FEM results for the triggering stage. The LSS detection criterion is defined and verified via analytical solutions and code validations on spherical Couette flows. The impact on a virtual electricity pylon is assessed. The code improvements and tutorials are available at github.com.

Effect of laser quenching process on surface hardness and wear performance of cylindrical slideway on the upper base of combined vibration separation equipment

Abstract Combined vibration equipment is widely used in the separation and classification of grain, mineral and other granular materials. The cylindrical slideway on the upper part of the base of the combined vibration equipment bears all the weight of the vibrating silo and the particulate matter in the vibrating silo during the vibration process, and supports the combined vibration of the vibrating silo and the particulate matter in the vibrating silo, the cylindrical slideway on the upper part of the base is seriously worn. The vibrating silo can only vibrate horizontally and linearly along the cylindrical slide on the upper part of the base and swing back and forth around the center of the bottom surface of the cylindrical slide on the upper part of the base. It is required that the cylindrical slide on the upper part of the base has good strength and toughness, and the contact surface has a hardness of more than 35HRC to ensure wear resistance. The effect of laser surface quenching process on the surface hardness of the upper cylindrical slide of the base is studied by using the method of three factors and four levels. The experimental results show that after laser surface quenching, the minimum surface hardness and the maximum surface hardness of the upper cylindrical slide of the base are 35.6HRC and 39.6HRC, which meet the hardness requirements of vibration equipment for the slide of the base. When 1450W laser quenching power, 500mm/min laser scanning speed and 2.25mm laser spot diameter are used, the maximum surface hardness will be 39.6HRC, which is about 38.6% higher than that of the pretreated sample. The maximum section hardness of test sample 14 after laser quenching reaches 388HV, which is about 1.25 times higher than that of the matrix in the quenching areas of samples 13, 15 and 16. It is close to the matrix hardness when it is 1.6mm away from the surface. The thickness of the surface hardened layer exceeds 0.6mm, indicating that the greater the laser power, the greater the thickness of the hardened layer. In the wear test, the minimum wear amount of sample 14 is 0.0331g, which is about 25.2% of the matrix wear amount of 0.1312g. The larger the laser power is, the smaller the scanning speed and spot diameter are, which plays a positive role in promoting the reduction of sample wear. We will use the laser surface quenching process parameters of sample 14: laser power 1450W, spot diameter 2.25mm and scanning speed 500mm/min to conduct laser quenching on the upper cylindrical slide surface of the base of the combined vibration equipment in order to obtain a thicker hardened layer and higher hardness, and greatly improve the service life, safety and stability of the combined vibration equipment.

Experimental and Numerical Investigation of a Surface Sliding Discharge in a Supersonic Flow with an Oblique Shock Wave

This study presents an experimental and numerical investigation on a surface sliding discharge in a supersonic airflow in the presence of an oblique shock wave. In experiments, flow Mach numbers were 1.20–1.68 in the shock tube combined with the discharge chamber. A single high-voltage 25 kV pulse sustains the plasma; the discharge current has a duration of ~500 ns. A surface sliding discharge is developed as a localized channel in a zone of interaction of an oblique shock wave with a boundary layer on the upper wall of the discharge chamber. The discharge channel acts as a linear source of heat and is at the origin of the induced shock wave. The flow field in the discharge chamber is spatio-temporally surveyed using high-speed shadowgraphy imaging with a frequency of up to 525,000 frames per second. The experiments show that the perturbed flow restored the initial structure after more than 100 μs. Numerical simulation with local energy input into the supersonic flow in a flat channel is carried out on the base of unsteady two-dimensional Navier–Stokes equations. It is determined that the dynamics of an induced shock wave are dependent on the energy input regime and on the flow parameters. The thermal energy release in the discharge channel of 0.22–0.29 J was estimated from a comparison of experimental data and numerical simulations.

Tribology and the Ocular Surface.

IntroductionTribology is known as the science of friction, lubrication and the determination of what occurs when two surfaces slide against one another. The required partners in this science are a minimum of two surfaces and relative motion. Tribology could be a key factor in dissecting the issues that surround and confound dry eye in patients as well as contact lens discomfort and intolerance. Specifically, it is this issue that is a potential causative underlying factor that could lead to conditions like lid wiper epitheliopathy (LWE).MethodsPeer-reviewed literature was reviewed as It pertains to ocular tribology and the application to the ocular anatomy. A PubMed review was performed using the keywords: tribology, friction, lid wiper epitheliopathy, contact lens, and dry eye. All manuscripts were reviewed for mentions of tribology and friction. The exact same process was performed with The Association for Research in Vision and Ophthalmology (ARVO) abstracts.ResultsIn relation to the ocular surface, tribology describes the mechanical interactions between the upper and lower lid wipers and the globe. The Stribeck curve can be applied, as the sliding partners are separated by a complex, lubricating tear film. The surface brush anatomy at the eye to eyelid juncture reduces friction and alters the Stribeck curve in favor of the hydrodynamic regime, allowing for high velocity movement with minimal wear. Changes to the tear film or the introduction of a contact lens can displace the Stribeck curve, increase friction, and induce wear thus leading to patient symptomology.ConclusionFurther studies may provide new insight into contact lens discomfort and ocular surface disease, including LWE; however, adaptation of tribology work performed in vitro to in vivo patient care is challenging.

Hydration Lubrication in Biomedical Applications: From Cartilage to Hydrogels.

ConspectusIn the course of evolution, nature has achieved remarkably lubricated surfaces, with healthy articular cartilage in the major (synovial) joints being the prime example, that can last a lifetime as they slide past each other with ultralow friction (friction coefficient μ = the force to slide surfaces past each other/load compressing the surfaces < 0.01) under physiological pressures (up to 10 MPa or more)). Such properties are unmatched by any man-made materials. The precise mechanism of low friction between such sliding cartilage tissues, which is closely related to osteoarthritis (OA), the most widespread joint disease, affecting hundreds of millions worldwide, has been studied for nearly a century, but is still not fully understood. Traditionally, the roles of load bearing by interstitial fluid within the cartilage bulk and that of thin exuded fluid films at the interface between the sliding cartilage surfaces have been proposed as the main lubrication mechanism. More recent work, however, suggests that molecular boundary layers at the surfaces of articular cartilage and other tissues play a major role in their lubrication. In particular, in recent years hydration lubrication has emerged as a new paradigm for boundary lubrication in aqueous media based on subnanometer hydration shells which massively reduce frictional dissipation. The vectors of hydration lubrication include trapped hydrated ions, hydrated surfactants, biological macromolecules, biomimetic polymers, polyelectrolytes and polyzwitterionic brushes, and close-packed layers of phosphatidylcholine (PC) vesicles, all having in common the exposure of highly hydrated groups at the slip plane. Among them, vesicles (or bilayers) of PC lipids, which are the most widespread lipid class in mammals, are exceptionally efficient lubricating elements as a result of the high hydration of the phosphocholine headgroups they expose. Such lipids are ubiquitous in joints, leading to the proposal that macromolecular surface complexes exposing PC bilayers are responsible for the remarkable lubrication of cartilage. Cartilage, comprising ∼70% water, may be considered to be a complex biological hydrogel, and studying the frictional properties of hydrogels may thus provide new insights into its lubrication mechanisms, leading in turn to novel, highly lubricious hydrogels that may be used in a variety of biomedical and other applications. A better understanding of cartilage lubrication could moreover lead to better treatments for OA, for example, through intra-articular injections of appropriate lubricants or through the creation of low-friction hydrogels that may be used as tissue engineering scaffolds for diseased cartilage.In this Account, we begin by introducing the concept and origin of hydration lubrication, extending from the seminal study of lubrication by hydrated simple ions to more complex systems. We then briefly review different modes of lubrication in synovial joints, focusing primarily on boundary lubrication. We consider modes of hydrogel lubrication and different kinds of such low-friction synthetic gels and then focus on cartilage-inspired, boundary-lubricated hydrogels. We conclude by discussing challenges and opportunities.

Robust ADP-Based Sliding-Mode Fault-Tolerant Control for Nonlinear Systems with Application to Spacecraft

This paper considers a novel fault-tolerant control (FTC) scheme for a category of cascade nonlinear systems with mismatched uncertainties and unknown actuator faults. The robust adaptive dynamic programming (RADP) is used to design a novel optimal sliding surface (SS) off-line, which renders the corresponding sliding-mode dynamics able to obtain robustness of stability to mismatched uncertainties. Subsequently, a simple sliding-mode control (SMC) with the adaptive fault compensation is developed to guarantee reachability of the sliding mode. Then, it is proven that the weight errors of neural networks (NN) of RADP and the closed-loop system are stable based on Lyapunov stability theory. In the simulation section, this proposed scheme is used to deal with the attitude FTC of a spacecraft, and simulation results verify the effectiveness of the proposed novel control scheme.

Development of scaffold-free micro-tissues to accelerate soft and hard tissue regeneration via delaying cellular senescence and regulating inflammation

Stem cell therapies are highly attractive due to their potential to repair the injured or diseased tissue and restore function. However, the most commonly used in clinical applications were digested cells (DCs), harvested using trypsin or dispase. And scaffold-based tissue engineering techniques are too complex to achieve clinical transformation. In this work, a novel approach to fabricate scaffold-free micro-tissues (MTs) with high homogeneity and quality on a large scale is reported. The MTs prepared in this way do not require scaffolds and could retain their cell-to-cell interactions and extracellular matrix (ECM). Firstly, temperature-sensitive polymer poly(N-isopropyl acrylamide) (PNIPAM) was adopted as a base coating for the surface of glass slides to facilitate the MTs detachment when the temperature changes from 37 °C to 4 °C. Then polydopamine (PD) was imprinted onto the substrates via microcontact printing (μCP) to fabricate micropatterned substrates. After that, negatively charged heparin was grafted onto the surface of PD patterns to create anti-adhesion networks. Given the rational design and all the components' virtues, we could prepare MTs on a large scale for soft and hard tissue repair with high performance. Compared to the enzyme-treated DCs, the MTs could accelerate soft and hard tissue regeneration via delaying cellular senescence and regulating inflammation.

Average Temperature Limits of the Dry Sliding Surface of Steel under High-Density Electric Current

Average Temperature Limits of the Dry Sliding Surface of Steel under High-Density Electric Current

Stability Satisfied Design and Construction of Excavated Soil Dumps in a Soft Soil Region in China

Dumping is the main disposal method of the excavated soil from underground engineering in China; however, due to a lack of construction experiences and technical standards, landslide disasters often occurred during rapid dumping of excavated soil in soft soil regions. In this paper, geotechnical tests were conducted on the excavated soil from a foundation engineering site in Hangzhou, where the excavated soil would be used to construct a piled mountain. On this basis, a numerical study was carried out to investigate the effects of the design parameters (heap height, slope gradient) and construction parameters (layer thickness, heap speed) on the dump stability and failure mode. The results show that the safety factor of the excavated soil dump decreases with increasing heap height, slope gradient, layer thickness, and heap speed. The potential slide surfaces are toe circle, and compared to layer thickness and heap speed, the heap height and slope gradient have more remarkable influence on the depth and area of potential slide mass. The heap height limit increases with a decrease in slope gradient, and the heap speed limit decreases with an increase in layer thickness. Under the premise of ensuring the slope stability, the optimal design and construction parameters were obtained, i.e., heap height 28 m, slope gradient 1:2.75, layer thickness 1.0 m, and heap speed 0.50 m/day. Compared to the original design scheme, the storage capacity increases by 20.01%, and the construction duration decreases by 30.25% in the optimal design.

Development of cost-effective fabrication process for on-site methamphetamine detection by adsorbable SERS substrate

In this study, the adsorbable SERS substrate was successfully fabricated on polydimethylsiloxane (PDMS) with the nanometer-sized roughness existing in a micrometer-sized roughness (nano-in-micro rough) structure which was completely transferred from the laser engraving aluminum (Al) mold by a replication process. Then the silver nanoparticle (Ag NPs) was deposited by magnetron sputtering. The physical morphology of the obtained samples was characterized by a field emission scanning electron microscope (FE-SEM). The ability for direct adsorb trace detection of the methylene blue (MB) on the glass slide surface was investigated. From the results, the SERS signal of the prepared adsorbable SERS substrates was influenced by the topography of the nano-in-micro rough feature and Ag NPs. It was found that combined nano-in-micro rough and microgroove structures exhibit high sensitivity of MB (10−5 M). In addition, the optimum adsorbable SERS substrate was then applied in practical application by adsorbing the methamphetamine (MAP) residues on the glass slide surface with a limit of 10−2 M, which could be expected to be an on-site screening platform for drugs detection.