Infant Sleep Disturbance Research Articles

Pengaruh Pijat Bayi terhadap Kualitas Tidur Bayi di Wilayah Kerja Puskesmas Sei Langkai Kota Batam

The infancy period is a crucial phase for a child's growth and development, where attention to sleep and stimulation is paramount. Sleep disturbances, such as sleeping less than nine hours per night, frequent awakenings, and difficulty returning to sleep, can affect a baby's emotions and development. This study aims to explore the impact of infant massage on the quality of sleep in infants. The method used was a pre-experimental study with a one-group pretest-posttest design, conducted at the Sei Langkai Public Health Center in Batam City from July to August 2023. The sample consisted of 15 infants selected through purposive sampling. The independent variable was infant massage, and the dependent variable was the quality of infant sleep. Data were analyzed using the Shapiro-Wilk normality test and the Wilcoxon test to assess differences before and after the intervention. The results showed a p-value of 0.001, which is less than 0.05, leading to the rejection of the null hypothesis (H0). This indicates that infant massage has a significant effect on the quality of infant sleep. In conclusion, infant massage is effective in improving the quality of infant sleep and can be recommended as an intervention to address sleep disturbances in infants in the Sei Langkai Public Health Center area.

THE EFFECT OF ROSE AROMATHERAPY (ROSA CENTIFOLIA) ON SLEEP DURATION FOR INFANTS AGED 0-28 DAYS AT PONCOWATI PUBLIC HEALTH CENTER LAMPUNG TENGAH IN 2022

ABSTRACT Approximately 75% of growth hormone in children is excreted during sleep. In Indonesia, quite a lot of babies have sleep problems, which is around 44.2% of babies experience sleep disorders such as frequently waking up at night, but more than 72% of parents consider sleep disturbances in infants not a problem or only consider it a small problem (Sekartini , 2012; Chandraini, 2021).Based on presurvey data by looking at data on baby sleep duration problems, which was carried out in 2 Puskesmas Kabupaten Lampung Tengah, namely at UPTD Puskesmas Bandar Jaya and UPTD Puskesmas Poncowati, it was found that 12 infants aged 0-28 days had problems sleeping at UPTD Puskesmas Bandar Jaya, while in In Poncowati Health Center, 20 babies aged 0-28 days had problems fulfilling the baby's sleep time, which was marked by fussy babies and crying, babies couldn't sleep if they weren't carried by their mothers.This study was to determine the effect of giving rose aromatherapy on the sleep duration of infants aged 0-28 days at Poncowati Health Center in Lampung Tengah in 2022.The research method was qualitative with questionnaire research instruments, thenumber of samples were 36 respondents (infants aged 0-28 days) taken by purposive sampling technique, data analysis using t test with a two group pretest posttest approach with control group design.Result of the study with an increase in the average quality of baby sleep after beinggiven rose aromatherapy (Rosa Centifolia) at the Poncowati Health Center, Lampung Tengah in 2022 was 33.33% higher than the average increase in infant sleep quality in the control group of 29.17%. From the t-test, the p value of 0.001 ˂ α (0.05) means that H0 is rejected and Ha is accepted, which means that there is an influence between the two variables.The conclusion is that there is an effect of giving rose aromatherapy on the sleepduration of infants aged 0-28 days. Therefore, it is suggested that this research can be an alternative to get good sleep quality for infants aged 0-28 days. Keywords : Infant, Rose Aromatherapy, Sleep Duration. Bibliography : (35) 2015-2021

Prenatal exposure to per- and polyfluoroalkyl substances and infant sleep disturbance: A prospective cohort study

BackgroundPrenatal exposure to per- and polyfluoroalkyl substances (PFAS) may adversely affect fetal brain development, yet no study has investigated the potential association between prenatal PFAS exposure and infant sleep. ObjectivesTo explore the associations of prenatal PFAS exposure with infant sleep disturbances during the first year of life in a prospective cohort study. MethodsWe recruited 4127 pregnant women from the Shanghai Birth Cohort (SBC) and followed their children from birth to 12 months old. A total of 2366 infants were included in the 6-month analyses, and 2466 infants in the 12-month analyses. Ten PFAS were quantified in blood serum collected in the first trimester. Sleep quality was measured using the Brief Infant Sleep Questionnaire. We used multiple linear regression and multinomial logistic regression to estimate the individual effects of PFAS on sleep outcomes. We utilized a quantile-based g-computation model to determine the joint effects of the PFAS mixture on infant sleep outcomes. Additionally, generalized estimating equation (GEE) models were performed to examine the longitudinal effects of PFAS exposure during pregnancy. ResultsIn infants aged 6 months, perfluorooctane sulfonate and perfluoroheptanoic acid were associated with a more than 2-fold risk of parent-reported sleep problems as severe. Perfluorodecanoic acid was associated with an increased risk of often or almost always snoring in one-year-old infants (relative risk ratios, 1.79; 95% CI, 1.12–2.86). PFAS mixtures were positively associated with nighttime awakenings both among infants aged 6 months (β, 0.11; 95% CI, 0.04–0.19) and 12 months (β, 0.11; 95% CI, 0.05–0.18). Prenatal exposure to PFAS were associated with longer sleep latency, increased nighttime awakenings, longer nocturnal wakefulness hours, snoring, and earlier sleep-onset time in infants aged 6–12 months, according to GEE models. ConclusionsOur study suggests that prenatal exposure to PFAS may increase the risk of sleep disturbance in infants.

Penerapan Aroma Therapy Bunga (rose centifolia) dan Pijat Bayi Terhadap Durasi Tidur Bayi Usia 3-12 Bulan di RSUD Poso

Introduction: The impact of sleep disturbances in infants is that the baby becomes often awake and fussy. The importance of sleep time in infants, then the duration of sleep in infants must be completely fulfilled so as not to adversely affect their development. One of the nursing interventions to treat sleep disorders in infants is massage and rose aroma therapy. The purpose of this study was to describe the application of nursing care with massage interventions and rose aroma therapy to increase infant sleep duration. Method : Descriptive research methods with a case study approach. Results : the patient's mother said her child had a cough with phlegm, fever for 3 days, the patient was fussy and restless, the patient slept only ± 8 hours a day, the patient often woke up at night due to coughing, the patient was difficult to sleep well, the patient's face looked pale, often seen yawning, temperature: 38.9 ° C RR 46x / min, pulse 120x / min, there are additional ronchi breath sounds, nursing diagnosis of airway clearance, hyperthermia, sleep pattern disorders. Nursing interventions for airway management, warm compresses, massage therapy and aromatherapy. Implementation of chest physiotherapy measures as well as giving 1ml combiven nebulizer + 2ml Nacl and suctioning. Giving tepid water sponge, doing baby massage and giving rose aroma therapy. The results of the evaluation of the patient's sleep increased from 8 hours to 12 hours a day, the patient was calm, the patient woke up at night only asking for milk and after waking up the patient could fall asleep again, coughing with phlegm was reduced, vesicular breath sounds, temperature: 37°C, RR: 38x/min. Conclusion: giving baby massage and rose aroma therapy can increase the duration of infant sleep. nurses can provide baby massage combined with rose aroma therapy to increase the duration of infant sleep.

Infant sleep predicts trajectories of social attention and later autism traits.

Children with neurodevelopmental disorders including autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) often experience sleep disturbances, but little is known about when these sleep differences emerge and how they relate to later development. We used a prospective longitudinal design in infants with a family history of ASD and/or ADHD to examine infant sleep and its relation to trajectories of attention and later neurodevelopmental disorders. We formed factors of Day and Night Sleep from parent-reported measures (including day/night sleep duration, number of naps in the day, frequency of night awakenings and sleep onset problems). We examined sleep in 164 infants at 5-, 10- and 14-months with/without a first-degree relative with ASD and/or ADHD who underwent a consensus clinical assessment for ASD at age 3. By 14-months, infants with a first-degree relative with ASD (but not ADHD) showed lower Night Sleep scores than infants with no family history of ASD; lower Night Sleep scores in infancy were also associated with a later ASD diagnosis, decreased cognitive ability, increased ASD symptomatology at 3-years, and developing social attention (e.g., looking to faces). We found no such effects with Day Sleep. Sleep disturbances may be apparent at night from 14-months in infants with a family history of ASD and also those with later ASD, but were not associated with a family history of ADHD. Infant sleep disturbances were also linked to later dimensional variation in cognitive and social skills across the cohort. Night Sleep and Social Attention were interrelated over the first 2 years of life, suggesting that this may be one mechanism through which sleep quality influences neurodevelopment. Interventions targeted towards supporting families with their infant's sleep problems may be useful in this population.

Sleep disturbances in infants and young children following an acquired brain injury.

Sleep disturbances impact over half of older children and teens with acquired brain injury (ABI) following critical care hospitalization but are underevaluated in infants and young children. Given the importance of sleep in brain development and healing after injury, we hypothesized sleep disturbances would be associated with worse neurodevelopmental outcomes in infants with ABI. We performed a retrospective cohort study of 68 children aged 2-32 months following critical care hospitalization for ABI. The Brief Infant Sleep Questionnaire assessed sleep disturbances. Bayley Scales of Infant and Toddler Development, third edition and Adaptive Behavior Assessment System, third edition assessed developmental and adaptive functioning outcomes, respectively. t tests compared sleep characteristics in infants with ABI to historical healthy controls. Spearman's correlation evaluated relationships among sleep and outcomes. Multiple linear regression investigated relationships controlling for demographic and ABI characteristics. Compared to healthy controls, children with ABI had shorter nighttime sleep duration (P = .01), longer daytime sleep duration (P < .001), and longer duration of nighttime awakenings (P < .001). Duration of night awakenings negatively correlated with Bayley Cognitive scores (Spearman's correlation = -.40). Night awakenings negatively correlated with worse Adaptive Behavior Assessment System, third edition General Adaptive Composite scores (Spearman's correlation = -.42). When controlling for demographic and ABI characteristics, ≥ 3 awakenings was significantly associated with worse Adaptive Behavior Assessment System, third edition General Adaptive Composite (β = -11.3; 95% confidence interval = -19.2, -3.5). Sleep disturbances are associated with poorer outcomes in infants and toddlers after ABI. Sleep is vital to recovery and a potentially modifiable target to improve outcomes. Klapp JM, Hall TA, Riley AR, Williams CN. Sleep disturbances in infants and young children following an acquired brain injury. J Clin Sleep Med. 2022;18(10):2387-2395.

Infant sleep and negative reactivity: The role of maternal adversity and perinatal sleep

Sleep during infancy contributes to the development and maintenance of infant regulatory functioning and may be an early risk marker for more difficult temperamental traits like negative reactivity. Further, maternal adverse childhood experiences (ACEs) may predispose individuals to greater sleep disturbances in adulthood and have been linked with sleep disturbances in both mothers and infants. Thus, examining maternal history of ACEs and maternal sleep difficulties during pregnancy and postpartum may provide insight into underlying risk factors affecting infant sleep difficulties and early temperament development. Fifty-nine mothers from a diverse, community sample (44% white) completed questionnaires on ACEs, maternal sleep, infant sleep, and infant temperament at 30-weeks gestation, 6-weeks postpartum, and 16-weeks postpartum. Results indicated that maternal ACES and sleep problems during pregnancy have long term implications for infant negative reactivity at 16-weeks, with significant indirect effects through maternal and infant sleep problems at 6-weeks. Addressing psychosocial functioning and prenatal sleep during pregnancy, particularly among women with high ACEs, may be a target of intervention to improve maternal and infant sleep health during the postpartum, and reduce the risk for difficult infant temperament.

P012 Maternal and infant stress during a bedtime separation: a pilot RCT

Abstract Background Behavioural sleep interventions to improve infant sleep disturbance commonly include extinction where an unwanted behaviour (night time crying) is periodically ignored. There have been conflicting findings regarding the impact of extinction methods on infant stress levels as measured with cortisol and as perceived by mothers and only one that measured cortisol at the time of the separation. This study aimed to compare a responsive method to extinction (controlled crying) and a control group evaluating subjective and objective stress for mother/infant dyads at the time of bedtime separation. Methods Mother/infant dyads were randomly allocated to behavioural sleep interventions (Responsive - n= 7, Controlled Crying - n=6 or Controls - n=4). Cortisol (two oral swabs on two nights at T2), maternal self-reported stress (Subjective Units of Distress - SUDS), and perceived infant distress (PIS) were compared over eight weeks. Correlations tested relationships between PIS, SUDS and infant cortisol levels. Mixed models analysis were used for cortisol analyses. Results There were no significant differences in cortisol levels between groups across time points but significant inter and intra-individual variability. Maternal stress was positively correlated with infant cortisol and PIS (p&amp;lt;0.05) and mothers in the Responsive group were significantly less stressed (p=0.02). Conclusion In this small sample, infant cortisol during bedtime separation was variable, elevated in all sleep interventions and not significantly different. Mothers were less stressed in the Responsive group. Findings indicate responsive methods are comparable to extinction and less stressful for mothers offering a possible gentler choice at bedtime separation.

Effect of Play2Sleep on mother-reported and father-reported infant sleep: a sequential explanatory mixed-methods study of a randomized controlled trial.

This study evaluated the effect on infant sleep of a novel intervention (Play2Sleep) that combined infant sleep information with self-modeled video feedback on parent-infant interactions. An explanatory sequential mixed-methods design consisting of a randomized controlled trial with 63 mother-father-infant triads randomized to Play2Sleep or comparison home visit interventions was used. We used repeated measures analysis of covariance to detect changes in infant night wakings, nocturnal wakefulness, and sleep durations and Wilcoxon signed rank test to evaluate changes in perception of infant sleep problems. Family interviews (n = 20) were used to explain the quantitative findings and analyzed qualitatively using thematic analysis. Play2Sleep was effective in reducing maternal-reported infant wakefulness, F(1,55) = 5.33, P = .03, partial η2 = .09, and the number of paternal-reported naps, F(1,58) = 4.90, P = .03, partial η2 = .08. Parents in the Play2Sleep group reported significant improvements in problematic infant sleep that were not observed in the comparison group; however, Play2Sleep was not effective in reducing the number of parent-reported night wakings. Information overwhelm, learning infant cues, and working together with a subtheme of father involvement were key qualitative themes developed to explain the quantitative results. Unplanned exploratory analyses revealed a significant improvement in maternal depression symptoms in the Play2Sleep group. This study suggests Play2Sleep could improve infant sleep by promoting parental awareness of infant cues and father involvement and improving maternal depression. Additional research is needed to determine the optimal number and timing of sessions. Registry: ClinicalTrials.gov; Name: Play2Sleep: Using Play to Improve Sleep; URL: https://clinicaltrials.gov/ct2/show/NCT02742155; Identifier: NCT02742155. Keys EM, Benzies KM, Kirk VG, Duffett-Leger L. Effect of Play2Sleep on mother-reported and father-reported infant sleep: a sequential explanatory mixed-methods study of a randomized controlled trial. J Clin Sleep Med. 2022;18(2):439-452.

Maternal emotional distress and infant sleep: A longitudinal study from pregnancy through 18 months.

This longitudinal study examined whether changes in maternal emotional distress (depressive, anxiety, and parenting-stress symptoms) predict changes over time in subjective and objective infant sleep. We recruited 226 Israeli expectant mothers (M age 28.8 ± 3.3), most representing the middle-upper socioeconomic class. Maternal depressive and anxiety symptoms were assessed in the third trimester of pregnancy. After delivery (3, 6, 12, and 18 months), infant sleep quality and duration were assessed for 5 nights using actigraphy and the Brief Infant Sleep Questionnaire. Maternal depressive and anxiety symptoms were reassessed, and maternal parenting-stress was measured at all postpartum assessments. The findings demonstrated significant correlations between maternal emotional distress and mothers' subjective ratings of infant sleep problems (rs >.16 and < .46). Latent trajectory analyses indicated no significant effects of changes in maternal emotional distress variables on changes in infant subjective or objective sleep. Post hoc power analyses demonstrated that we had enough statistical power to reject the null hypothesis. The results suggest that mothers with higher emotional distress symptoms-and especially those with parenting-stress symptoms-are more likely to experience their infant's sleep as problematic. However, our results challenge the assumption that maternal emotional distress symptoms contribute to infant sleep disturbances over time. The findings are relevant to mothers with mild to moderate emotional distress symptoms and must not be generalized to mothers who experience major clinical depression. Future studies should evaluate whether maternal emotional distress interacts with other risk factors, such as infant temperament, to predict infant sleep disturbances. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

Perinatal depression as a risk-factor for infant sleep disturbances: Subjective data from a case-control study

IntroductionPerinatal period is characterized by a broad range of physical, psychological and relational changes. Maternal perinatal depression (PD) is defined as an episode of major depression with the onset from pregnancy to the first year after delivery. Depressive symptoms influence the earlier mother-child interaction and impact on child cognitive, affective and behavioral development.ObjectivesPurpose of our study was to evaluate the consequences of PD on sleep-wake patterns in the early stages of infant development. We aim to investigate the presence of poor sleep in infants/ toddlers and also to identify differences in sleep ecology variables.MethodsWe enrolled, from December 2019 to September 2020, a clinical sample of children born from women with PD (N=19, m.a.=13,7, SD= 7,6) and a healthy control group (N=21, m.a.=15,5, SD=5,43). Infant sleep data were obtained from the Brief Infant Sleep Questionnaire (BISQ). Poor sleepers were defined by the following criteria: &gt;3 night wakings, nocturnal wakefulness &gt;1 hr or total sleep duration &lt;9 hr. Maternal depression was assessed with clinical and psychometric evaluation. T-test was used for comparison between the two samples.ResultsStatistical analysis indicates that there were not significant differences between the two groups concerning night wakings (p= .678), nocturnal wakefulness (p= .815), total sleep duration (p= .209) and nocturnal sleep onset time (p= .475).ConclusionsOur findings suggest that PD is not a risk-factor in the onset of infant sleep problems. Probably negative parentig, affective disengagement, delegation in maternal care and sedative effects of pharmacotherapy may affect mother’s perception of her infant’s sleep.

Implementation of Infant Behavioral Sleep Intervention in a Diverse Sample of Mothers

ABSTRACT Objective/Background Behavioral Sleep Interventions (BSI) is an efficacious class of treatment approaches for infant sleep disturbance. Little is known about BSI implementation in the real world. Objectives were to a) examine the prevalence of BSI implementation and related factors in a diverse sample of US mothers; b) assess racial-ethnic group differences; and c) examine predictors of BSI implementation. Participants Participants included mothers (n= 353) with an infant (6–18 months) from one of the three racial-ethnic groups: White Hispanic (n= 113), White non-Hispanic (n= 122), Black non-Hispanic (n= 118). Methods Respondents completed an online survey assessing BSI implementation, familiarity, barriers, sleep knowledge, cognitions, and sleep patterns. Results Approximately one-third (36%) of the sample endorsed BSI implementation and 59% reported BSI familiarity. Black non-Hispanic mothers were more likely to report stopping a BSI prior to completion (OR = 4.92, p <.05) and more likely to hear about BSI from a health-care professional (OR = 1.32, p <.05) compared to White non-Hispanic mothers. Racial-ethnic group differences were identified for a variety of sleep practices, including bedsharing, independent sleep onset, and score on a validated measure of problematic sleep. No racial-ethnic group differences were found in BSI implementation, cognitions, or barriers. BSI implementation was predicted by BSI familiarity, more maternal education, and cognitions around infant self-soothing. Conclusions Differential BSI implementation does not appear to be a major driver of sleep disparities, although Black non-Hispanic mothers who decide to implement BSI do report notably lower completion rates. Future studies should examine alternative mechanisms of sleep disparities as well as strategies to promote sleep health in diverse families.

0978 Snoo: A Wellness Device To Improve Infant Sleep

Abstract Introduction One of the primary contributors to new parent sleep deprivation is infant sleep disturbances. Evidence shows that increasing sleep in infants has a positive effect on parental sleep. SNOO, a wellness device, was developed to provide sleeping babies 3 of the 5 S’s (safe swaddling, sound and swinging) in a response fashion (increasing levels of motion and white noise if babies cry) to soothe crying and improve infant sleep. Methods The current study compares infant sleep derived from SNOO to a reference group of a compilation of 13 peer reviewed studies of normative sleep data on sleep in traditional cribs/bassinets. Participants were 7157 babies using SNOO beginning within one week of birth and for at least 6 hours per night for 6 months. Sleep metrics calculated on a day to day basis include Longest Sleep Period: Maximum uninterrupted sleep at night (7 PM - 7 AM); Total Sleep Duration: Total time spent sleeping at night (7 PM - 7 AM); and Night Awakenings: Number of times parents attended to the baby (10 PM - 6 AM). Results Improvement in the longest sleep duration varied with age. Across the 6 month collection period, longest sleep period increased between 42 minutes - 2 hours 0 minutes and total sleep duration increased between 33 minutes - 1 hour 24 minutes. Babies in SNOO averaged one less waking per night compared to the reference population (1.09±.89 vs 1.89 ±1.1). The improvements in all three sleep metrics were statistically significant with p’s &amp;lt; 0.0005 across all ages from birth to 6 months. Conclusion This large-scale study suggests that infant sleep can be significantly improved by using SNOO compared to babies who slept in normal cribs or bassinets. We believe there are myriad areas of public health that may be positively impacted as a result of this significant level of improvement of infant sleep. Support Happiest Baby, Inc.

Massage with lavender aromatherapy reduced sleep disturbances on infant

To determine the effectiveness of lavender aromatherapy's massage on reducing sleep disturbances in infants. a pre-experimental one group pre-posttest design involving thirteen infants aged 6-12 months who were selected purposively with criteria having sleep disturbances. Massage is given for 30min in three consecutive days by using two drops of oil lavender aromatherapy mixed in 50ml of oil-based. Data collection used a valid and reliable questionnaire, which is Sleep Disturbances Scale in Children (SDSC), one day before and after the intervention. Data were analyzed using the Wilcoxon Test. Massage using lavender aromatherapy is effective in reducing sleep disturbances in infants especially in the dimension of starting and maintaining sleep, somnolence disorders, and interruption of wakefulness sleep transition dimension (p<0.001). Massage with Lavender aromatherapy is recommended as an alternative intervention to reduced sleep disturbances on infants aged 6-12 months.

Effectiveness of an mHealth Intervention for Infant Sleep Disturbances

Bedtime problems and night wakings are highly prevalent in infants. This study assessed the real-world effectiveness of an mHealth behavioral sleep intervention (Customized Sleep Profile; CSP). Caregivers (83.9% mothers) of 404 infants (age 6 to 11.9 m, M = 8.32 m, 51.2% male) used the CSP (free and publicly available behavioral sleep intervention delivered via smartphone application, Johnson’s® Bedtime® Baby Sleep App). Caregivers completed the Brief Infant Sleep Questionnaire–Revised (BISQ-R) at baseline and again 4 to 28 days later. Changes in sleep patterns were analyzed, based on sleep problem status (problem versus no problem sleepers; PS; NPS). Sleep onset latency improved in both groups. Earlier bedtimes, longer continuous stretches of sleep, as well as decreased number and duration of night wakings, were evident in the PS group only. The BISQ-R Total score, total nighttime sleep, and total 24-hour sleep time improved for both groups, with a greater change for the PS group. Further, caregivers of infants in the PS group decreased feeding (bedtime and overnight) and picking up overnight, and perceived better sleep. Bedtime routine regularity, bedtime difficulty, sleep onset difficulty, and caregiver confidence improved for both groups, with the PS group showing a greater magnitude of change. Thus, a real-world, publicly available, mHealth behavioral sleep intervention was associated with improved outcomes for older infants. Intervention recommendations resulted in changes in caregivers’ behavior and improvements in caregiver-reported sleep outcomes in infants, in as few as 4 days.

Child's respiratory and sleep health following mid-trimester amniocentesis Danielius Serapinas and Daiva Bartkeviciene Special articles.

The aim was to investigate the rates of respiratory and sleep disturbances in infants whose mothers experienced amniocentesis. Infants whose mothers have undergone midterm amniocentesis (between 16 and 20 weeks) and no invasive procedure (controls) were enrolled. The study analyzed 50 infants whose mothers have undergone amniocentesis (amniocentesis group) and 47 controls. Amniocentesis group had higher incidence of sleep disturbances: 30 cases (60 %), compared with 11 controls (23.4 %) (P = 0.001). In the amniocentesis group there were 7 children (14 %) with asthma, while in the control group, asthma was confirmed in 1 child (2.1 %) (P = 0.032). Our data triggers the hypothesis that associations between midterm amniocentesis, child's asthma and sleep disturbances may exist. These preliminary results reveal the importance of further studies and the need for the analysis of long term effects of invasive testing.

The Impact of Infantile Atopic Dermatitis on Patients' and their Families' Quality of Life

Background Atopic dermatitis (AD) is detrimental to the infants' and their families' quality of life. We aimed to study the disease effects on Iranian infants and their familiesapplying theinfants’ dermatitis quality of life index (IDQOL), and the dermatitis family impact questionnaires (DFI). Materials and Methods Questionnaires (DFI and IDQOL) were translated into Persian and retranslated into English. Three experts assessed the content validity of the questionnaires by evaluating the relevance and transparency of the tools. Test-re-test was used to evaluate the questionnaires reliability. The reliability and internal consistency of the IDQOL and DFI were accessed by Cronbach’s alpha coefficient which was 0.74. The construct validity of the questionnaires was assessed using the Pearson correlation index to evaluate convergent and divergent validity. 50 Infants with AD fulfilling the criteria as well as their parents entered the study in Mashhad, Iran, in 2017. An independent-sample t-test was used to compare mean scores and one-way ANOVA was used to analyze other data. Results Intense itching (64%), taking one to more than two hours to get the child to sleep (52%), and three to more than five hours of infant sleep disturbance (34%) were significant. Family expenses (70%), and emotional stress (68%) affected the families' quality of life prominently. There were significant differences between the average DFI scores and other allergic diseases, both among infants suffering from AD (p = 0.04), and their families (p = 0.03(. Conclusion The Persian versions of the questionnaires (DFI and IDQOL) have validly and reliably measured both groups' quality of life. Theyexperienced remarkable disturbances in their quality of life.

0816 Effectiveness of an mHealth Intervention for Infant Sleep Disturbances

0816 Effectiveness of an mHealth Intervention for Infant Sleep Disturbances

Adaptation and study of the measurement properties of a sleep questionnaire for infants and pre-school children

Abstract Introduction Although sleep disturbances in infants and toddlers are common, there is no suitable validated tool in Spanish to evaluate sleep disorders. The Brief Infant Sleep Questionnaire (BISQ) is a well-established multidimensional questionnaire widely used internationally. Objectives To adapt the BISQ questionnaire to Spanish and analyse its reliability and validity. To explore its feasibility, both in the clinical context, and in epidemiological research. Methods Participants were parents of children between 3 and 30 months of age. The adaptation to Spanish (BISQ-E) was achieved by using both back translation and consensus, following the international guidelines.Reliability was determined by means of test–retest and measurement of agreement (Kappa value) between 2 forms of administration of the questionnaire (self-administration and clinical interview). Construct validity was established by analysing its correlation with a sleep diary. Results A total of 87 families/children participated. The test–retest reliability undertaken in 60 subjects was r = 0.848 (P Conclusions The Spanish adaptation of the BISQ shows overall adequate validity and reliability for the evaluation of sleep in infants and pre-school children. Its use as a clinical tool, or for clinical-epidemiological research studies, is feasible.

Adaptation and study of the measurement properties of a sleep questionnaire for infants and pre-school children

Although sleep disturbances in infants and toddlers are common, there is no suitable validated tool in Spanish to evaluate sleep disorders. The Brief Infant Sleep Questionnaire (BISQ) is a well-established multidimensional questionnaire widely used internationally. To adapt the BISQ questionnaire to Spanish and analyse its reliability and validity. To explore its feasibility, both in the clinical context, and in epidemiological research. Participants were parents of children between 3 and 30 months of age. The adaptation to Spanish (BISQ-E) was achieved by using both back translation and consensus, following the international guidelines.Reliability was determined by means of test-retest and measurement of agreement (Kappa value) between 2forms of administration of the questionnaire (self-administration and clinical interview). Construct validity was established by analysing its correlation with a sleep diary. A total of 87 families/children participated. The test-retest reliability undertaken in 60 subjects was excellent; r=0.848 (P<0.001). The kappa value was 0.939 (95% CI: 0.858-1.00, P<0.001).The agreement between BISQ-E and the sleep diary was analysed in 27 families/children, with statistically significant values being obtained for the following variables: bedtime (r=0.731), hours of night sleep (r=0.726), hours of daytime sleep (r = 0.867), and number of nocturnal awakenings (r=0.888) (P<0.001). The Spanish adaptation of the BISQ shows overall adequate validity and reliability for the evaluation of sleep in infants and pre-school children. Its use as a clinical tool, or for clinical-epidemiological research studies, is feasible.