Skin Window Research Articles

Cytological examination of experimental contact allergy using the skin window technique.

AllergyVolume 17, Issue 6 p. 547-557 CYTOLOGICAL EXAMINATION OF EXPERIMENTAL CONTACT ALLERGY USING THE SKIN WINDOW TECHNIQUE12 PER WOLF-JÜRGENSEN, PER WOLF-JÜRGENSEN From med. dep. F, Copenhagen County Hospital, Glostrup. Denmark, Head: M. Schwartz, M.D.Search for more papers by this author PER WOLF-JÜRGENSEN, PER WOLF-JÜRGENSEN From med. dep. F, Copenhagen County Hospital, Glostrup. Denmark, Head: M. Schwartz, M.D.Search for more papers by this author First published: December 1962 https://doi.org/10.1111/j.1398-9995.1962.tb03124.xCitations: 30 1 Presented at meeting of “Dansk Selskab for Allergiforskning” on Dec. 7th, 1962. 2 Supported by a grant from “Kong Chr. X's Fond”. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume17, Issue6December 1962Pages 547-557 RelatedInformation

Tissue Eosinophilia in Hypersensitivity Reactions as revealed by the Human Skin Window

THE elusive eosinophil has been credited with a variety of diverse pathophysiological functions. It has been postulated as a carrier of histamine1,2 though this has been disputed3,4. This cell has been shown to contain substances exhibiting anti-histaminic activity5, and to possess phagocytic ability. It is capable of ingesting sensitized erythrocytes6 and mast cell granules7. Eosinophil granules form the nidus and may supply the basic protein for the formation of Charcot–Leyden crystals8. It has also been suggested that the eosinophil plays a part in the sequence of events leading to secondary antibody formation9,10. This view has been challenged recently by Litt11, who demonstrated that antibody in association with antigen initiates the aggregation of eosinophils, a view which is supported by the work of Cohen et al.12.

Human Skin Window: A Cytologic Method for the Study of Allergic Inflammation

The cytology of acute inflammation was originally described by Metchnikoff in experimental animals. Rebuck and Crowley (1) have advanced the technic of human skin windows which confirmed the description of the acute inflammatory cycle. The basic sequences consisted of an early migration of phagocytic granulocytes, reinforcing available tissue macrophages. These phagocytes were supplemented by migrating lymphocytes and blood mononuclears (monocytes) which hypertrophied to form additional macrophages. In the present study we have employed the skin window technic to study the inflammatory response to a contact allergen.

Skin windows and the action of the reticuloendothelial system in man.

Skin windows and the action of the reticuloendothelial system in man.

A New Qualitative Defect of Leukocyte Function in Ulcerative Colitis

Summary The pattern of leukocytic exudation in patients with ulcerative colitis has been studied by the skin window technique. A majority of patients with ulcerative colitis (13 of 19 patients studied) showed a difference from the pattern of exudation seen in normal subjects consisting of an excessive number of basophilic leukocytes. The biochemical and pathogenetic implications of this finding are discussed.

Local action of thyroxin on amphibian metamorphosis. III. Formation and perforation of the skin window in Rana pipiens larvae effected by thyroxin‐cholesterol implants

Local action of thyroxin on amphibian metamorphosis. III. Formation and perforation of the skin window in Rana pipiens larvae effected by thyroxin‐cholesterol implants