Skin Graft Research Articles

Short-term morbidity following primary closure, skin grafting and flap reconstruction after surgical resection of extremity soft-tissue sarcomas: Pushing the limits of limb preservation.

Short-term morbidity following primary closure, skin grafting and flap reconstruction after surgical resection of extremity soft-tissue sarcomas: Pushing the limits of limb preservation.

Donor site in anterolateral thigh (ALT) free flaps: A systematic review of closure techniques and introduction of a management algorithm.

Donor site in anterolateral thigh (ALT) free flaps: A systematic review of closure techniques and introduction of a management algorithm.

Management of hypertensive leg ulcers: A French national survey.

Management of hypertensive leg ulcers: A French national survey.

Atypical care of burned patients is typical in war: Adapting old dogma for maximal survival.

Atypical care of burned patients is typical in war: Adapting old dogma for maximal survival.

Clinical outcomes of reconstruction on tissue defects with thin anterolateral thigh flap versus commonly used free soft flaps: A meta-analysis.

Clinical outcomes of reconstruction on tissue defects with thin anterolateral thigh flap versus commonly used free soft flaps: A meta-analysis.

Deep Dissecting Hematoma, an Often Misdiagnosed Lesion: Case-Control Analysis of Risk Factors and Wound-Healing Prognosis.

Deep Dissecting Hematoma, an Often Misdiagnosed Lesion: Case-Control Analysis of Risk Factors and Wound-Healing Prognosis.

Blue light therapy device for wound healing

<p>Cuts, diabetic ulcers, and pressure sores are examples of chronic skin wounds that pose a serious healthcare danger because of their delayed healing rates. This problem emphasizes the necessity of creating noninvasive, economical, and successful wound treatment plans. Conventional treatments, such as skin grafting, negative pressure wound therapy, and hyperbaric oxygen therapy, have demonstrated effectiveness; nevertheless, they are frequently costly, intrusive, and have possible side effects. On the other hand, blue light treatment has become a viable substitute due to its antimicrobial characteristics and capacity to encourage cellular restoration. However, there is a crucial gap in the development of a portable, noninvasive, and cost-effective photobiomodulation device for wound treatment and monitoring, despite its demonstrated potential in wound healing. This work aims to address this gap by creating a novel blue light therapy tool specifically suited for wound healing. The gadget allows for controlled blue light exposure and real-time temperature monitoring to minimize overheating. It has a portable arm housing with integrated blue light strips, a temperature sensor, and an integrated fan. An STM 32 microcontroller powers the system’s pulse width modulation (PWM) technology, which modifies light intensity and therapy duration in response to conditions unique to each wound. This novel strategy seeks to improve the effectiveness of wound healing, lower the likelihood of adverse effects, and offer patients and healthcare providers a workable alternative that is noninvasive, inexpensive, and easy to use.</p>

Accelerated wound healing of enzymatically debrided deep dermal burn wounds after the use of fish skin (Kerecis Omega3 Wound®) in comparison to Suprathel®.

Accelerated wound healing of enzymatically debrided deep dermal burn wounds after the use of fish skin (Kerecis Omega3 Wound®) in comparison to Suprathel®.

Extended Anterolateral Thigh Flaps: Maximum Size for Covering Cancerous Defects.

The anterolateral thigh perforator flap is frequently used for massive soft-tissue defect reconstruction. Cadaver perfusion examinations of isolated anterolateral thigh flaps have suggested a maximum skin area that may be vascularized based on the perforating vessels (ie, 250 cm 2 ). Therefore, this study aimed to evaluate a series of consecutive cases involving use of extended anterolateral thigh flaps for oncologic reconstruction of massive soft-tissue defects. To our knowledge, this is the largest study of extended anterolateral thigh flaps at a single center. Patients who underwent transfers of anterolateral thigh flaps exceeding 250 cm 2 at our institution between April 2018 and December 2022 were retrospectively identified. The operative data and results were analyzed. Thirty-eight flaps in 36 cases were included. The 38 flaps consisted of 31 free flaps and 7 pedicled flaps. The average skin paddle size was 363 ± 101 cm 2 (range, 250-660 cm 2 ). The donor site was primarily closed in 7 flaps. The remaining 31 flaps required skin grafting to ensure donor-site closure. Neither total nor partial flap loss was observed. Four patients had wound dehiscence due to tightness. Three patients had surgical-site infections. Two patients had seromas. The postoperative courses of the 5 patients were complicated by partial skin graft loss at the donor sites. The anterolateral thigh flap is versatile and reliable for the treatment of massive oncological defects. Even flaps much larger than 250 cm 2 can usually be harvested safely based on 2 to 4 perforators without special techniques, such as compound flaps or additional vessel anastomoses.

Autologous Chin Augmentation with Cervico-mental Angle Correction in Burn Scar Contracture.

Autologous Chin Augmentation with Cervico-mental Angle Correction in Burn Scar Contracture.

Keloid formation after congenital toe syndactyly release is associated with preoperative toe hypertrophy: A retrospective observational clinical study.

Keloid formation after congenital toe syndactyly release is associated with preoperative toe hypertrophy: A retrospective observational clinical study.

Successful Treatment of a Chronic Venous Ulcer Caused by an Undiagnosed Arteriovenous Fistula: A Case Report.

This case report presents a 53-year-old male patient with a chronic venous ulcer (CVU) on his left lower limb that persisted for over 10 years despite various treatments. The patient had a history of a gunshot wound to the left femoral area 12 years prior. Despite regular follow-ups and multiple interventions, including debridement and split-thickness skin grafting, the ulcer showed poor healing. Further diagnostic imaging, including angiography and computed tomography, revealed an previously undiagnosed arteriovenous fistula (AVF) at the left external iliac artery and femoral artery level. The patient underwent a minimally invasive endovascular intervention involving percutaneous transluminal angioplasty and stent graft placement. This approach successfully closed the AVF, significantly reducing venous hypertension and promoting wound healing. One month after operation, the CVU showed complete healing without recurrence. This case underscores the importance of considering AVFs in the differential diagnosis of CVUs, especially in patients with a history of trauma or surgery. It also highlights the effectiveness of endovascular techniques in treating complex vascular anomalies and their associated complications.

Clinical outcomes of closed versus open simple ankle fractures patterns requiring soft tissue reconstruction: A prospective comparative observational study.

Clinical outcomes of closed versus open simple ankle fractures patterns requiring soft tissue reconstruction: A prospective comparative observational study.

Purse-string suture: A fast and effective option for closing the donor area of a clavicular full-thickness skin graft.

Purse-string suture: A fast and effective option for closing the donor area of a clavicular full-thickness skin graft.

Redefining the concept of the elderly burn patient: Analysis of a multicentre international dataset.

The elderly are highly vulnerable to major burn injuries. Typically, 'elderly' is accepted as ≥ 65 years of age. This cut-off is arbitrary, lacks a robust evidencebase and is potentially damaging from a clinical-decision-making perspective. The study objective was to utilise a large international dataset of major burns to stratify mortality risk by age and objectively define 'elderly' patients with significantly higher risk of poor outcome. We performed a sub-analysis of the RE-ENERGIZE clinical trial dataset. RE-ENERGIZE included 1200 patients admitted to 54 burn centres worldwide with 2nd and/or 3rd degree burns, who were expected to require skin grafting. In a first-of-its-kind age stratification study, we stratified major burns patients by five-year age intervals. Logistic regression and Cox proportional hazards analyses were performed with three-month mortality and time-to-discharge-alive (TTDA) as the primary and secondary outcomes. Three-month mortality was 15.41 %. Age was associated with three-month mortality upon multivariable logistic regression analysis (p = 0.000, OR=1.06, CI=1.05-1.08), independently of total burn surface area burned (TBSA%), Acute Physiology and Chronic Health Evaluation II (APACHE II) and Charlson Comorbidity Index (CCI). Age 80 + was independently associated with increased mortality and TTDA, when compared to all referent 5-year age groups (p ≤ 0.000-0.043). The Lethal Dose 50 (LD50) for the 80 + group was 20.5 %. We present a new threshold of risk stratification in patients with major burns; Patients ≥ 80 years have a significantly poorer outcome, irrespective of injury severity, resultant critical illness severity, and variables including comorbidities, which has implications for prognostication and management decisions.

Nile tilapia skin in burn wound healing: A scoping review.

Nile tilapia skin in burn wound healing: A scoping review.

Autologous Meshed Graft Healing Within the Interstice versus Surrounding Adhered Split Thickness Skin Sites: Where Should Tissue Biopsies be Taken to Assess Tissue-Level Histoarchitecture?

Autologous Meshed Graft Healing Within the Interstice versus Surrounding Adhered Split Thickness Skin Sites: Where Should Tissue Biopsies be Taken to Assess Tissue-Level Histoarchitecture?

The Effect of Intraoperative Use of Intact Fish Skin Grafts for High-Risk Patients With Class 3 and Class 4 Wounds Who Undergo Urgent/Emergent Abdominal Surgery

Surgical site infections (SSIs) remain a significant concern in high-risk patients undergoing abdominal surgeries with class 3 and class 4 wounds. This study examines the efficacy of Intact Fish Skin Grafts (IFSGs) in reducing SSIs. Conducted at two urban hospitals from July 2021 to November 2023, the study included 31 patients who underwent emergency abdominal procedures. IFSG was applied at the fascia level, and patients were monitored for 40 days postoperatively. The results demonstrated SSI rates of 5.9% in class 3 wounds and 7.1% in class 4 wounds, which is significantly lower than historical averages. The median hospital length of stay was reduced to 4 days for class 3 and 6 days for class 4 wounds. These findings suggest that IFSG presents a promising alternative to standard closure techniques, offering improved clinical outcomes and potential cost savings.

Comparison of bupivacaine infiltration with and without tramadol for post-operative analgesia in split skin graft donor sites: A prospective randomized controlled study

Background: Split skin graft (SSG) creates a new partial-thickness wound at the donor site. Donor site pain is the most common concern in the post-operative period. Local infiltration of the donor site is an effective way to reduce immediate post-operative pain. Prolonged pain relief is always sought after. Aims and Objectives: In this study, we intend to know if the addition of tramadol to bupivacaine local infiltration prolongs post-operative analgesia. Materials and Methods: Sixty patients posted for SSG with donor site in the thigh were included in the study. They were divided into Group BB, who received local infiltration of the donor site with 0.25% bupivacaine, and Group BT who received local infiltration with 0.25% bupivacaine and 50 mg tramadol. Visual analog scale (VAS) score up to 24 h, time of 1st rescue analgesia, total analgesic consumption in 24 h, and side effects were noted. Results: Patients in Group BB had significantly higher VAS scores at 8, 9, 10, 11,12, and 16 h as compared to Group BT. The time of first rescue analgesia was higher in Group BT with 721.03±54.79 min as compared to Group BT which had 463.21±43.89 min and these values were statistically significant. Total rescue analgesia consumption was significantly higher in Group BB with 2928.57±377.96 g when compared with Group BT which had 2068±257.88 g. There were no significant side effects. Conclusion: Local infiltration of the donor site with bupivacaine and tramadol combination decreased the post-operative pain score, total analgesic consumption, and prolonged the time of first rescue analgesia as compared to local infiltration of donor site with bupivacaine alone with minimum side effects.

Personalized 3D-printed retainers as a novel approach to maintain the auricular morphology after corrective surgery for cryptotia: a retrospective study

Cryptotia, a congenital auricular deformity, presents both aesthetic and functional challenges. This study evaluates the efficacy of personalized 3D-printed retainers in maintaining auricular morphology following corrective surgery for cryptotia. A total of 69 patients with unilateral cryptotia were enrolled in this single-center retrospective cohort study. All patients underwent corrective surgery, and postoperative management included the use of retainers in the experimental group, while the control group did not use any supportive devices. The effect of surgery and retainers relied on the measurement and analysis of auricular indicators preoperatively, immediately postoperatively, and at the last follow-up. Patient satisfaction was assessed using the Likert scale and Visual Analog Scale. Significant improvements in auricular indicators were observed postoperatively in both groups. At the last follow-up, no statistical significances were observed in the differences of key indicators between the affected and normal ears in the experimental group, whereas significant differences were observed in the control group. The experimental group demonstrated a significantly high satisfaction rate (82.25%). Subgroup analysis revealed that the retainers were particularly effective in patients without the need for free skin grafting. This study highlighted the personalized 3D-printed retainers in maintaining auricular morphology and reducing the recurrence after corrective surgery for cryptotia.