Simple Approach For Fabrication Research Articles

Silicon nanosheets confined into nitrogen-doped porous carbon microcage enabling efficient lithium storage

Silicon (Si) is regarded as the promising next-generation commercial anode in high energy lithium-ion batteries (LIBs), attributed to its natural abundance, high theoretical capacity (4200 mAh g−1) and low voltage profile (<0.5 V). However, the huge volume change and tremendous capacity fading of silicon during lithiation/de-lithiation have been hindering its practical application. Herein, a facile and scalable method was proposed to prepare the Si nanosheets limited in 3D porous N-doped carbon micro cages (Si@NCM) particles with ternary oxygen-bridged covalent chemical bond, i.e., Si–O–C bonding. As a kind of anode materials, the Si@NCM rendered an extremely surprising reversible capacity of 930.2 mAh g−1 after 2000 cycles at a current density of 5 A g−1 at ambient temperature. More interestingly, it afforded an overwhelming capacity of 950.7 mAh g−1 after 3000 cycles at 20 A g−1 at 80 °C, with 89.8% capacity retention, and an excellent rate capability of 594.8 mAh g−1 at 50 A g−1. The impressive electrochemical performance was ascribed to its multi-scaled network structure and moderate covalent bonding, which enhanced Li+ diffusion kinetics and accommodated the volume expansion of the silicon. This simple fabrication approach holds great commercial possibility in practical application of next-generation advanced LIBs.

Improving parameters of inorganic perovskite solar cells by more than one spin coating method

This work reports the fabrication process for preparation of perovskite films with good quality morphology and optimal thickness by a simple process of more than one spin coating or multiple spin coating (MSC) method. It should be noted that perovskite films with good quality morphology and optimal thickness are prepared without antisolvent engineering in full air conditions. In this work, we obtained an optimal good power conversion efficiency (PCE) value for CsPbI3 perovskite solar cells (PSCs) at 11.69%. Although, the PCE result is not high enough, however, this MSC method provides a simple and uncomplicated approach for fabrication of PSCs. (PCE) value for at 11.69%. CsPbI3.

Amidation reaction to derive waterborne, tolerant, and optically transparent solid slippery and superhydrophobic coatings

Separate and lubrication-free association of low surface energy with hierarchically featured and highly smooth interfaces yield two distinct and prospective bio-inspired wettability—superhydrophobicity and solid slippery properties, respectively. However, the derivation of such bio-inspired wettability with high optical transparency—following a simple, completely waterborne, non-fluorinated and scalable fabrication approach is an extremely challenging task to achieve. Here, a simple amidation reaction between thioester and amine groups is rationally extended for aqueous processing of strategically selected small molecules to attend desired outputs through formation of nanoparticles. An aqueous reaction mixture of selected non-fluorinated small molecules provided a stable (for 30 days) dispersion of nanoparticles (size ∼210 nm). While the ‘in-situ’ deposition of the reaction mixture yielded completely waterborne, optically transparent, physically and chemically durable lubrication-free solid slippery coating on a planar substrate, a highly deformable superhydrophobic coating on porous and fibrous substrates was obtained following a rapid and facile post-deposition of the prepared nanoparticles. The prepared solid slippery coating remained efficient in sliding the beaded droplets of various (e.g., polar and non-polar) liquids having a wide range (70.2 mN/m to 22.3 mN/m) of surface tension. The embedded slippery property remained unaltered even after exposure of prepared coating to extremes of temperatures and severe abrasive conditions—including continuous drop of 250 g of sand, sandpaper abrasion with a distance of 500 cm under an applied load of 25 KPa, adhesive tape peeling for 500 cycles, pencil (6H) & knife scratching, and prolonged (15 days) treatments of extremes of pH, seawater, river water, etc. The synthesized superhydrophobic coating on porous and fibrous-substrate remained efficient in sustaining repetitive and large physical deformations and other relevant abrasive exposures.

High-performance photodetector arrays for near-infrared spectral sensing

Spectral sensing is an emerging field driven by the need for fast and non-invasive methods for the chemical analysis of materials in agri-food, healthcare, and industrial applications. We demonstrate a near-infrared spectral sensor, based on a scalable fabrication process and combining high responsivity, narrow linewidth, and low noise. The sensor consists of 16 resonant-cavity-enhanced photodetectors, each showing a unique spectral response consisting of narrow peaks. The spectral sensor thereby covers the wavelength range between 890 and 1650 nm, where organic materials show relevant spectral features from first and second overtones. For the fabrication of the detector arrays, we propose a simple and scalable fabrication approach that yields largely improved device characteristics with respect to the grey-scale electron-beam lithography process reported earlier. Through a series of five optical lithography steps, tuning layers of silicon nitride are deposited stepwise to obtain 16 different thicknesses and reduced surface roughness. With this novel fabrication approach, the obtained photodetectors achieve an average peak linewidth of 55 nm, a maximum peak responsivity of 0.3 A/W, and high suppression of the non-resonant background. We also demonstrate the impact of these improvements on the sensing performance for two relevant problems through an experiment and a set of simulations. With lateral dimensions of ∼1.4 × 1.4 mm2, the proposed photodetector array can be the key to robust, portable, and low-cost sensing instrumentation for on-site material analysis in various application fields.

Modulation of MG-63 Osteogenic Response on Mechano-Bactericidal Micronanostructured Titanium Surfaces.

Despite recent advances in the development of orthopedic devices, implant-related failures that occur as a result of poor osseointegration and nosocomial infection are frequent. In this study, we developed a multiscale titanium (Ti) surface topography that promotes both osteogenic and mechano-bactericidal activity using a simple two-step fabrication approach. The response of MG-63 osteoblast-like cells and antibacterial activity toward Pseudomonas aeruginosa and Staphylococcus aureus bacteria was compared for two distinct micronanoarchitectures of differing surface roughness created by acid etching, using either hydrochloric acid (HCl) or sulfuric acid (H2SO4), followed by hydrothermal treatment, henceforth referred to as either MN-HCl or MN-H2SO4. The MN-HCl surfaces were characterized by an average surface microroughness (Sa) of 0.8 ± 0.1 μm covered by blade-like nanosheets of 10 ± 2.1 nm thickness, whereas the MN-H2SO4 surfaces exhibited a greater Sa value of 5.8 ± 0.6 μm, with a network of nanosheets of 20 ± 2.6 nm thickness. Both micronanostructured surfaces promoted enhanced MG-63 attachment and differentiation; however, cell proliferation was only significantly increased on MN-HCl surfaces. In addition, the MN-HCl surface exhibited increased levels of bactericidal activity, with only 0.6% of the P. aeruginosa cells and approximately 5% S. aureus cells remaining viable after 24 h when compared to control surfaces. Thus, we propose the modulation of surface roughness and architecture on the micro- and nanoscale to achieve efficient manipulation of osteogenic cell response combined with mechanical antibacterial activity. The outcomes of this study provide significant insight into the further development of advanced multifunctional orthopedic implant surfaces.

Fabrication of SERS Substrates Based on Porous- Si Nanostructures and Silver Nanoparticles for Application in Identification of Carbendazim

In this work, we present a quick and simple approach for fabrication of active-surface-enhanced Raman scattering (SERS) substrates based on silver nanoparticles (AgNPs) and porous silicon nanostructures (denoted by Si/Ag substrate). SERS substrates were fabricated by a 3-stage-process including the deposition of Au nanoparticles on Si wafer, etching for porous Si wafer, and coating Ag NPs on porous Si to produce SERS-active layer. To control the uniformity and cleanliness of the SERS substrate, sputtering technique was used to coat Au and AgNPs. The absorption spectra of the Si/Ag substrates exhibited a strong surface plasmon resonance absorption band of AgNPs at 425 nm. Using Si/Ag substrates to detect carbenzadim (CBZ) residue dispersed in acetone has shown that Si/Ag substrates morphology greatly affected the Raman intensity of carbendazim which opens up a promising and potential approach using SERS spectroscopy for food, environment and especially pharmaceutical applications.&#x0D; Keywords: Raman, SERS, plasmon, nanoparticles, carbendazim.&#x0D; &#x0D;

Development of fibroblast/endothelial cell-seeded collagen scaffolds for in vitro prevascularization.

The development of vascularized scaffolds remains one of the major challenges in tissue engineering, and co-culturing with endothelial cells is known as one of the possible approaches for this purpose. In this approach, optimization of cell culture conditions, scaffolds, and fabrication techniques is needed to develop tissue equivalents that will enable in vitro formation of a capillary network. Prevascularized equivalents will be more physiologically comparable to the native tissues and potentially prevent insufficient vascularization after implantation. This study aimed to culture human umbilical vein endothelial cells (HUVECs), alone or in co-culture with fibroblasts, on collagen scaffolds prepared by simple fabrication approaches for in vitro prevascularization. Different concentrations and ratios of HUVECs and fibroblasts seeded on collagen gel and sponge scaffolds under several culture conditions were examined. Cell viability, scaffolds morphology, and structure were analyzed. Collagen gel scaffolds showed good cell proliferation and viability, with higher proliferation rates for cells cultured in a 2:1 (fibroblasts: HUVECs) ratio and kept in endothelial cell growth medium. However, these matrices were unable to support endothelial cell sprouting. Collagen sponges were highly porous and showed good cell viability. However, they became fragile over time in culture, and they still lack signs of vascularization. Collagen scaffolds were a good platform for cell growth and viability. However, under the experimental conditions of this study, the HUVEC/fibroblast-seeded scaffolds were not suitable platforms to generate in vitro prevascularized equivalents. Our findings will be a valuable starting point to optimize culture microenvironments and scaffolds during fabrication of prevascularized scaffolds.

Whole‐Device Mass‐Producible Perovskite Photodetector Based on Laser‐Induced Graphene Electrodes

AbstractPerovskites have attracted enormous attention in optoelectronics, owing to their excellent optoelectronic properties, low‐cost constituents, and simple solution fabrication approaches. Despite significant advances in large‐scale production of perovskite films, electrode layers—indispensable components of an optoelectronic device—are typically fabricated by depositing noble metals onto perovskite films using complicated techniques, which hinder the large‐scale production of optoelectronic devices. Herein, a whole‐device mass‐producible perovskite photodetector is developed using low‐cost and high‐scalability direct laser writing (DLW) of laser‐induced graphene on a flexible polyimide (PI) film as electrodes, followed by depositing a formamidinium cesium lead triiodide perovskite film using solution methods as the sensing element. The fabricated device exhibits a broad bandwidth (from 365 to 940 nm), a decent responsivity (15.1 mA W−1) and detectivity (5.12 × 1013 Jones), a large photo‐to‐dark current ratio (47.2), and short response time (rise time = 0.4 s and decay time = 0.4 s). The device demonstrates a high humidity (relative humidity = 85%) stability, a long‐term (&gt;48 days) stability, and a high flexibility (0°/90° bending cycles &gt; 1000 times) after encapsulation. The developed whole‐device scalable fabrication sheds light on the mass production and commercialization of perovskite based optoelectronic devices and flexible electronics.

Electric field-mediated regulation of enzyme orientation for efficient electron transfer at the bioelectrode surface: A molecular dynamics study

Surface immobilization with favorable orientation of biocatalysts is critical for developing bioelectrochemical devices. To improve the performance of electrochemical electrodes, biocatalyst surface modification and engineering has been attempted via expensive and complex fabrication processes. For proper orientation and deposition of biomolecules on the surface, application of external electric field (EF) to small molecules has been suggested. Here, to the best of our knowledge, a unidirectional external EF was applied for the first time to oxygen-reducing enzymes with high catalytic activity and a Laccase-graphene interface was constructed using computational methods. The external EF rotated the active site of laccase, resulting improvement in the electron transfer rate compared to enzymes physically immobilized on graphene. The external EF fabrication process was also evaluated for graphene congeners (graphene oxide (GO) and reduced GO (rGO)). The morphology of the electrode surface was visualized, and computational methods were applied to verify binding conformation, orientations of dipole moment, secondary structure, and binding stability. Graphene was the most promising material compared to GO and rGO by 10 and 5 % for DET rate, respectively. Results suggest that using an external EF to favorably orientate the Laccase-graphene interface may be a simple, economical, and efficient approach for bioelectrode fabrication.

Slippery liquid-infused porous surface (SLIPS) with super-repellent and contact-killing antimicrobial performances

Slippery liquid-filled porous surfaces (SLIPS) have attracted extensive research attention for their unique repellent properties, but such surfaces typically lack essential bactericidal activity and cannot defend against the spread of bacteria once bacterial contamination occurs. Herein, a slippery liquid-infused porous surface (SLIPS), endowed with both super-repellent and contact-killing antimicrobial performances is reported. Firstly, polystyrene (PS) based porous structures are developed via a facile microphase separation technique with poly(ethylene glycol) (PEG) as the sacrifice template. The porous surface was then covalently modified by 3-(trimethoxysilyl)propyl dimethyl undecyl ammonium chloride (QAC-Silane) to get the contact-killing antimicrobial performances. After lubricant (silicone oil) is introduced to the porous structure, the SLIPS surface demonstrates remarkably high super-repellence against both Gram-positive and negative bacteria, and also maintains essential contact-killing antimicrobial activities from the fixed QAC-11 groups, once the infused lubricant was depleted. Also, this surface demonstrates a reduced coefficient of friction (COF) of ∼56% as compared to that of the control flat surface. Moreover, this SLIPS surface can be easily realized on various substrates, such as silica glass, polycarbonate (PC), polyethylene terephthalate (PET), polyethylene (PE) and silicone catheter tube. Owing to its simple, low-cost and fast fabrication approach, this kind of surface may find unique biomedical applications where an effective antibacterial performance and lubricity are highly needed.

Development of ZnCo alloy enclosed in N-doped carbon with hexagonal close packing crystal phase inspires potential oxygen evolution reaction

The tuned crystal structure and electrical properties of metal alloy nanoparticles can vary their catalytic capabilities. In the present study, hexagonal close-packed (hcp) ZnCo nanoalloy enclosed in N-doped carbon (hcp-ZnCo@NC) are created using a simple fabrication approach and are characterized via various complementary techniques. The fabricated hcp-ZnCo@NC shows remarkable oxygen evolution reaction (OER) performance in alkaline conditions (1 M KOH). The synthesized hcp-ZnCo@NC with Zn/Co ratio of ≈ 1:1 exhibits overpotentials of 282 mV at a current density of 10 mA cm−2 with a smaller tafel slope of 51.9 mV dec−1, and good stability of 30 h. These characteristics of the present material are better when compared with the state of the art. The enhanced efficiency of the hcp-ZnCo@NC is because of its favorable electron transfer characteristics and high conductivity. Hence, this study offers a new perception for future applications due to the unique crystal phase-linked electrical properties.

Nanoscale Electrically Driven Light Source Based on Hybrid Semiconductor/Metal Nanoantenna.

A micro- or nanosized electrically controlled source of optical radiation is one of the key elements in optoelectronic systems. The phenomenon of light emission via inelastic tunneling (LEIT) of electrons through potential barriers or junctions opens up new possibilities for development of such sources. In this work, we present a simple approach for fabrication of nanoscale electrically driven light sources based on LEIT. We employ STM lithography to locally modify the surface of a Si/Au film stack via heating, which is enabled by a high-density tunnel current. Using the proposed technique, hybrid Si/Au nanoantennas with a minimum diameter of 60 nm were formed. Studying both electronic and optical properties of the obtained nanoantennas, we confirm that the resulting structures can efficiently emit photons in the visible range because of inelastic scattering of electrons. The proposed approach allows for fabrication of nanosized hybrid nanoantennas and studying their properties using STM.

Fabrication and pH Sensing Characteristics Measurement of Back Gate ZnO Thin Film Planar FET

Here in we demonstrate the design of a low-cost zinc oxide (ZnO) thin-film planar transistor-based pH sensor controlled by the bottom gate fabricated by a fairly simple fabrication approach. The performance of the fabricated device is evaluated by electrical as well as surface characterization. The surface morphology is analyzed by scanning electron microscope (SEM) and atomic force microscopy (AFM) and it shows surface properties that are essential required device to function as a pH sensor. The fabricated thin-film FET comprises Zinc Oxide (ZnO) as a channel layer of length 6 μ m and thickness 200 nm, Silicon Nitride (Si3N4) as a passivation layer, and Aluminum (Al) as a contact layer. The effect on pH sensitivity for varied channel lengths (6 μ m, 12 μ m, and 15 μ m) is also examined and optimum results have been achieved at channel length = 6 μ m. The change in threshold voltage (△Vth) & change in current ( $\triangle I_{\max \limits }$ ) are used as a sensing metrics to analyze the sensing performance of the device. The device shows excellent pH sensitivity in terms of average current and average voltage sensitivity 120.97 mA/pH and 97.85 mv/pH respectively at pH ranging from 3.2 to 11.1 with best pH stability (linearity) for pH value 4 to 10. The voltage sensitivity is higher than the Nernstian value (59 mv/pH) at room temperature.

Design and fabrication of an electrochemical‐based nanofibrous immunosensor for detection of prostate cancer biomarker, PSMA

AbstractConvenient medical diagnostics and treatments can replace conventional healthcare procedures because of their fast and profitable applications with reduced infection risk. Meanwhile, early diagnosis of cancer is a leading research subject due to the high fatality rate of the disease and being a vital precursor in the treatment effectiveness. Electrochemical‐based micro‐biosensors are the best candidates for measuring particular biomarker concentrations in body fluids. To address this need, we used a simple fabrication approach to develop an effective immunosensor for the early detection of cancer, in particular prostate cancer. The carbon fibers, obtained from the electrospinning technique, decorate the sensor's working electrode. The available immobilization surface for antibodies doubled by taking advantage of carbon nanofibers. This modification would increase sensor sensitivity and simplify steps of immobilization. Furthermore, the prostate‐specific membrane antigen (PSMA) biomarker, a more reliable substitute for prostate‐specific antigen in prostate cancer diagnosis, was evaluated in cell culture media as a provisional model. Compared to other works, the present sensor uses more accessible materials and simple techniques. Still, it functions reasonably in the linear range of 10–200 ng/ml with the sensitivity of 22.1 pg/ml and detection limit of 9.5 ng/ml without the need for labeling or any other complicated processes. Specific sample concentrations were assessed with sensors and a commercial PSMA ELISA assay kit. According to obtained results, the present sensors have sufficient accuracy in PSMA detection.

Bio-fabricated nanocomposite hydrogel with ROS scavenging and local oxygenation accelerates diabetic wound healing.

Chronic wounds, especially diabetic wounds, involve abnormally long inflammatory periods due to their pathological microenvironment of high reactive oxygen species (ROS) levels and lack of blood vessels. Here, via a mild, simple and feasible fabrication approach, a sustained oxygenation system is proposed, consisting of MnO2 nanosheets and a dual-network hydrogel fabricated from natural biomaterials including silk fibroin (SF) and carboxymethyl cellulose (CMC). Compared with the initial value (61.09 kPa), the compression modulus of the dual-network hydrogel increased by 116.2% through the coordination of strong covalent bonds and sacrificial coordination bonds constructed by enzymatic crosslinking and UV-irradiation crosslinking; the intrinsic shear-thinning effect endows the dual-network hydrogel with satisfactory injectable properties to be customized as a predetermined shape to accommodate the irregular wounds of diabetes. The encapsulated MnO2 nanosheets can catalyze the excessive ROS into necessary O2in situ and, after co-incubating with the SF/CMC@MnO2 hydrogels, cells in oxidative stress show significantly lower ROS (3 times) and higher O2 (17 times) levels that are conductive to relieving oxidative stress, promoting angiogenesis and reducing inflammation in vivo. Meanwhile, these SF-based hydrogels can offset the overexpression of matrix metalloproteinases (MMPs) in diabetic wounds (more than 80%) and promote remodeling of the extracellular matrix. Eventually, wound healing rates >76% in 7 days and 100% in 14 days were achieved by the bio-fabricated nanocomposite hydrogel and are remarkably faster than the commercial dressing healing rates (<30% in 7 days and <80% in 14 days). These results indicate that this bio-fabricated hydrogel system with multiple and customizable functions has great promise in the personalized clinical care of chronic wounds.

Keratin Functionalized Electrospun Pei/Pan Microfiltration System for Anionic Dye Removal: A Simple and Sustainable Fabrication Approach

Keratin Functionalized Electrospun Pei/Pan Microfiltration System for Anionic Dye Removal: A Simple and Sustainable Fabrication Approach

A simple approach for fabrication of superhydrophobic titanium surface with self-cleaning and bouncing properties

A simple, scalable, rapid and eco-friendly method for the fabrication of superhydrophobic (SHP) titanium surface was developed using rapid breakdown anodization (RBA) for the first time. The desired hierarchical surface morphology for superhydrophobicity is achieved by controlling the RBA process parameters and low surface energy modification by using stearic acid (SA). The prepared samples were characterized using Field emission scanning electron microscope (FESEM), Energy-dispersive X-ray spectroscopy (EDX), Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS), and water contact angle (WCA) measurements. The anodized samples showed islands of TiO2 microclusters with complex hierarchical structures randomly distributed in the passive TiO2 matrix. Ti sample anodized at 30 V was hydrophobic with a WCA of ~ 130° and a sliding angle > 30°, whereas the one anodized at 50 V was superhydrophobic with a WCA of ~ 154° and a sliding angle of 10° after the low surface energy modification. The growth mechanism of RBA leading to the formation of pores and microclusters was understood from the current-time transient data analysis. Our results show that the sustained oxidation of titanium and pore growth by chemical or field-assisted dissolution reactions governed the final morphology of the anodized sample. The superhydrophobic sample exhibited excellent self-cleaning, adhesion (bouncing) properties and abrasion resistance.

Electrochemical DNA/aptamer biosensors based on SPAAC for detection of DNA and protein

Electrochemical DNA/aptamer (E-DNA/aptamer) biosensors based on target-induced change in conformation of surface-anchored oligonucleotides have been developed in recent years. In order to improve electrode surface modification versatility, we developed a simple approach for fabrication of DNA-conjugated electrochemical platform on screen-printed electrodes for the detection of DNA and protein. The conjugation of oligonucleotides was conducted based on a copper-free strain-promoted azide-alkyne cycloaddition (SPAAC), in which the dibenzocyclooctyne (DBCO)-modified oligonucleotides were covalently conjugated to azide-terminated gold-plated screen-printed carbon electrodes. As a proof-of-principle, we employed the p53 DNA probe and anti-VEGF165 DNA aptamer as the receptors to determine the versatility of the electrode surface modification. The proposed E-DNA/aptamer sensors showed a limit of detection of 0.76 nM for p53 DNA target and 8.2 pM for VEGF165 protein, respectively. In addition, both sensors demonstrated satisfactory stability in 50% fetal bovine serum samples. The results indicated that the E-DNA/aptamer sensors fabricated by SPAAC reaction performed well when compared to those fabricated via the conventional gold-thiol coadsorption or CuAAC reaction. The proposed approach has a great potential to fabricate biosensors on less-expensive substrates for detection of DNA or proteins.

3D printed cross-shaped terahertz metamaterials with single-band, multi-band and broadband absorption

Terahertz metamaterial absorbers (THz MAs) have attracted significant attention for their unprecedented ability to modulate the incident terahertz wave effectively. Prevalent manufacturing of THz MAs has been mainly restricted by the traditional micro-nano fabrication technique due to their micro-scale characteristic size of the unit cell. However, conventional fabrication technique has been suffered by the involvement of multi-step and time-consuming processes as well as expensive facilities. To overcome these bottlenecks, we have proposed a novel and efficient fabrication technique based on the projection micro-stereolithography 3D printing followed by the electron beam evaporation coating to manufacture the THz MAs additively. A typical cross-shaped MA is taken into account as the prototype to demonstrate the effectiveness of the proposed technique. A broadband and a triple-band MA are then realized by combining four cross-shaped resonators and the alternative of the cross-shaped resonator. Both experimental measurements and theoretical simulation exhibit the expected absorption performance of three types of 3D printed MA samples in the THz band. It can be estimated that the proposed 3D printed technique provides a simple but universal fabrication approach for the THz MAs and paves the avenue toward its foreseeable applications on the versatile design and manufacturing of functional THz devices.

Free-Standing Multilayer Molybdenum Disulfide Memristor for Brain-Inspired Neuromorphic Applications.

Recently, atomically thin two-dimensional (2D) transition-metal dichalcogenides (TMDs) have attracted great interest in electronic and opto-electronic devices for high-integration-density applications such as data storage due to their small vertical dimension and high data storage capability. Here, we report a memristor based on free-standing multilayer molybdenum disulfide (MoS2) with a high current on/off ratio of ∼103 and a stable retention for at least 3000 s. Through light modulation of the carrier density in the suspended MoS2 channel, the on/off ratio can be further increased to ∼105. Moreover, the essential photosynaptic functions with short- and long-term memory (STM and LTM) behaviors are successfully mimicked by such devices. These results also indicate that STM can be transferred to LTM by increasing the light stimuli power, pulse duration, and number of pulses. The electrical measurements performed under vacuum and ambient air conditions propose that the observed resistive switching is due to adsorbed oxygen and water molecules on both sides of the MoS2 channel. Thus, our free-standing 2D multilayer MoS2-based memristors propose a simple approach for fabrication of a low-power-consumption and reliable resistive switching device for neuromorphic applications.