Grocery List Research Articles

Understanding food consumer behavior using projective methods and the big five personality traits model: The case of traditional Mexican cheeses

AbstractThis research aimed to use two projective methods and the Big Five Personality Traits (BFPT) model to study food consumer behavior in the case of traditional Mexican cheeses. Based on an online survey (n = 197), this study employs the Word Association and Mason‐Haire's Shopping List projective techniques with two shopping lists (traditional vs. supermarket). Several factors influencing consumers' perceptions of traditional cheeses were identified, such as hedonism, sensory characteristics, quality and freshness. The shopping list allowed the identification of factors related to food consumption and consumer personality traits. Conscientiousness and Neuroticism were associated with the profile of the consumer who purchases food in supermarkets. In contrast, the personalities of Agreeableness and Openness were associated with the profile of the consumer of traditional Mexican cheeses. The results of this research could be helpful in promoting and marketing traditional foods, considering consumers' personality traits.Practical applicationsThis research identified consumer perceptions of traditional cheeses produced in the central region of Mexico and the personality traits associated with the consumer profile of these food products. The results can be of great use to the cheese‐producing agroindustry, considering that consumers are aware that by purchasing these products, they are contributing to the development and support of the local economy. Therefore, it is essential for producers and sellers to consider the attributes that consumers associate with traditional cheeses, such as artisanal and local characteristics, hedonic value, and consumers' personality traits.

Food Resource Management and Healthy Eating Focus Associates with Diet Quality and Health Behaviors in Low-Income Adults.

Nutrition education and food resource management (FRM) can assist food-insecure individuals in acquiring healthy and affordable food. We aimed to assess the relationships between FRM skills and healthy eating focus with diet quality and health-related behaviors in low-income adults during the COVID-19 pandemic. This cross-sectional study was conducted using an online survey of 276 low-income adults living in a low-food-access community in Northeast Connecticut. Through analysis of covariance, adults who usually or always had a meal plan, considered reading nutrition labels important, made a grocery list, were concerned about their food healthiness, and rated their diet quality as very good/excellent reported higher diet quality (frequency-based and liking-based scores) (p < 0.05 for all). Individuals who considered reading food labels very important and reported having a good diet reported less frequent pandemic-related unhealthy behaviors (consumption of candy and snack chips, soda or sugary drinks, weight gain, smoking) (p < 0.001). Furthermore, higher-frequency-based diet quality was associated with lower risk of overweight or obesity (OR: 0.37; 95% CI: 0.18, 0.76; p-trend < 0.01). Thus, FRM skills and healthy eating focus were associated with higher diet quality and healthier self-reported changes in diet, weight, and smoking behaviors during the pandemic.

A single-blinded, randomized, parallel intervention to evaluate genetics and omics-based personalized nutrition in general population via an e-commerce tool: The PREVENTOMICS e-commerce study

BackgroundPersonalized nutrition (PN) has been proposed as a strategy to increase the effectiveness of dietary recommendations and ultimately improve health status. ObjectivesWe aimed to assess whether including omics-based PN in an e-commerce tool improves dietary behavior and metabolic profile in general population. MethodsA 21-wk parallel, single-blinded, randomized intervention involved 193 adults assigned to a control group following Mediterranean diet recommendations (n = 57, completers = 36), PN (n = 70, completers = 45), or personalized plan (PP, n = 68, completers = 53) integrating a behavioral change program with PN recommendations. The intervention used metabolomics, proteomics, and genetic data to assist participants in creating personalized shopping lists in a simulated e-commerce retailer portal. The primary outcome was the Mediterranean diet adherence screener (MEDAS) score; secondary outcomes included biometric and metabolic markers and dietary habits. ResultsVolunteers were categorized with a scoring system based on biomarkers of lipid, carbohydrate metabolism, inflammation, oxidative stress, and microbiota, and dietary recommendations delivered accordingly in the PN and PP groups. The intervention significantly increased MEDAS scores in all volunteers (control—3 points; 95% confidence interval [CI]: 2.2, 3.8; PN—2.7 points; 95% CI: 2.0, 3.3; and PP—2.8 points; 95% CI: 2.1, 3.4; q < 0.001). No significant differences were observed in dietary habits or health parameters between PN and control groups after adjustment for multiple comparisons. Nevertheless, personalized recommendations significantly (false discovery rate < 0.05) and selectively enhanced the scores calculated with biomarkers of carbohydrate metabolism (β: −0.37; 95% CI: −0.56, −0.18), oxidative stress (β: −0.37; 95% CI: −0.60, −0.15), microbiota (β: −0.38; 95% CI: −0.63, −0.15), and inflammation (β: −0.78; 95% CI: −1.24, −0.31) compared with control diet. ConclusionsIntegration of personalized strategies within an e-commerce–like tool did not enhance adherence to Mediterranean diet or improved health markers compared with general recommendations. The metabotyping approach showed promising results and more research is guaranteed to further promote its application in PN.This trial was registered at clinicaltrials.gov as NCT04641559 (https://clinicaltrials.gov/study/NCT04641559?cond=NCT04641559&rank=1).

A Survey of On Personalized E-Commerce

The Personalized e-commerce application proposed by us incorporates several essential modules to provide a seamless and convenient shopping experience for users. The app utilizes GPS or network-based location services to determine the user's location and search for nearby shops within a specified radius of 5 km. The app also allows users to set preferences such as cuisine, product category, and price range, which are used to filter the list of nearby shops and display only those that match the user's preferences. The app provides relevant information for each shop, such as its name, address, product offerings, prices, and rating options to get directions to the selected shop. Additionally, the app will enable users to make purchases either by redirecting them to the shop's website or by implementing an in-app purchasing process. With these features, the proposed personalized e-commerce app offers a personalized and convenient shopping experience for users, allowing them to find and purchase products from nearby shops with ease.

Grocery Management System

This Application builds a user-friendly grocery management system in Java. Users can create and manage shopping lists by adding items, adjusting quantities, and marking purchases. The system goes beyond basic lists by offering functionalities like item categorization (dairy, produce, etc.) and optional expiration date tracking. This allows for smarter planning by generating shopping lists based on low stock and expiring items. Additionally, the Java application can integrate with unit prices (optional) to estimate total grocery costs before heading to the store. This user-friendly system empowers individuals or families to streamline their grocery management, potentially saving time, money, and reducing food waste

Enhancing adherence to recommended food practices in Norwegian kindergartens: The role of knowledge and application of national guidelines for food and meals

Aim: This study sought to investigate the relationship between knowledge and the practical application (including grocery lists, meal plans and food-related pedagogical plans) of Norwegian national guidelines for food and meals in kindergartens, together with the quality of food served in adherence to these guidelines. The study also examined the frequency of daily meals provided and the quality of food served. Moreover, it explored whether pedagogical staff’s knowledge of these guidelines was linked to their practical application. Method: Data were collected from 324 kindergarten staff members by means of a web-based questionnaire distributed to both public and private kindergartens in Norway between 2018 and 2020. Univariate and multivariate linear regression analyses were employed to explore associations between pedagogical staff knowledge of the content of national guidelines and food quality in line with national guidelines. Results: Of the 324 participating kindergartens, two-thirds were private providers and one-third were public. A total of 155 kindergartens were in eastern Norway, 41 in mid-Norway, 50 in the west, 48 in the south and 26 in northern Norway. The study found that pedagogical staff’s knowledge and the use of national guidelines were positively associated with better food quality and adherence to guidelines for food and meals in kindergartens. In addition, the frequency of daily meals provided by kindergartens was associated with food quality. Conclusions: An association was found between pedagogical staff’s knowledge and application of national guidelines for food and meals, and the quality of food served in adherence to these guidelines. In addition, a correlation was observed between the frequency of meals provided by a kindergarten and food quality. These findings suggest that stressing the development of a better understanding of the content of national guidelines for food and meals could potentially enhance food and meal practices in kindergartens, but further research to explore this possibility is warranted.

A Cross-Sectional Study of Grocery Shopping Factors of Importance among Food-Insecure African Americans.

The objective of this study was to (1) assess via cross-sectional survey the prevalence of food insecurity among African Americans [AAs] after their most recent grocery shopping trip, and (2) examine the grocery shopping factors of importance and characteristics of food-insecure AA grocery shoppers. Most (70.4%) were food-insecure. Food-insecure grocery shoppers were significantly more likely to be younger, less educated, who often skipped meals and/or practiced fasting, accessed a food pantry, were SNAP recipients, were considered to not be in "good" health, and who had higher BMI compared to food-secure shoppers (p ≤ 0.03 * for all). Our data showed that AAs shopped for groceries a mean 2.20 ± 1.29 times per week, for low prices (72.1%), without a weekly budget (58.9%), with a grocery list (44.6%) or using an app (27.6%), for high-quality vegetables (27.5%), for good customer service (22.9%), for store brands (20.8%) and name brands (17.9%).Food-insecure shoppers were significantly more likely to grocery shop more times per week, have a weekly budget, and use an app, but were significantly less likely to report store brands, name brands, good customer service, and high-quality vegetables as grocery factors of importance (p ≤ 0.03 * for all). Grocery strategies such as shopping with a grocery app and/or grocery list could help food-insecure AAs reduce grocery trips, promote meal planning to save money, and avoid skipping meals/fasting, while eating healthier.

Access Control Using Facial Recognition

The field of smart home technology has grown by leaps and bounds over the last few decades. This development has made several new products available that can add convenience and security to facility. People became aware of smart home devices with the introduction of the smart thermostat, but these thermostats were only the beginning to smart homes. Smart devices helps people manage their sched-ules, grocery lists, home lighting and even the home security. These devices work together to make life a bit easier as well as safer. One group of such smart home security devices that are gaining popularity are smart door locks. Smart door locks are also seeing new innovative features being added recently where some companies are adding the capability of facial recognition to the locks. With nothing but the face, it’s now possible for a door lock can be operated. As far back as 2016, manufacturers started talk-ing about smart locks with face recognition. The innovation has continued to grow as several main-stream tech devices with facial recognition like the phones and handheld devices with facial recogni-tion unlock features. In smart door locks, the device uses facial recognition, leveraging advanced processing and analytics to identify a person’s facial attributes at the door. KEY WORDS Access control, facial recognition, door locks, security.

Grocery Shop Application

The grocery shop app is a user-friendly mobile application designed to streamline the grocery shopping experience. With a clean and intuitive interface, users can easily browse a wide selection of products, add items to their virtual cart, and conveniently place orders for home delivery or in-store pickup. The app features personalized recommendations based on past purchases, real-time inventory updates, and a robust search function for efficient product discovery. Users can create and manage shopping lists, take advantage of exclusive deals and discounts, and enjoy a seamless checkout process with various payment options. The app aims to enhance the overall convenience and efficiency of grocery shopping, providing users with a modern and hassle-free way to meet their daily food and household needs. KEYWORDS - Fresh,Convenient, Variety, Quality, Affordable, Fresh produce, Organic options,Dairy products, Household essentials

Abstract P483: Food Purchase Priorities and Healthy Food Purchase Supports and Barriers for U.S. General and Low-Income Consumers: A Quantitative Survey

Introduction: Identifying priorities and attributes that influence food purchase decisions will inform interventions and strategies to promote healthy eating. Aim: This study aimed to identify food purchase priorities and healthy food purchase supports and barriers for the general population and those with limited household income. Methods: Participants were recruited by a market research company in May 2023 and were required to be ≥ 18 years old, not work in healthcare/medical/nutrition or advertising/public relations/marketing/market research and be the primary/shared food decision maker for the household. Recruitment quotas ensured age, income, gender and geographic region approximated 2022 US census data (n=1,182) (Census-representative group, CRG). A sample with limited income and participation in federal food or healthcare programs (low-income group, LIG) was also recruited (n=506). The survey was administered online in May and June 2023. Differences between LIG and CRG were assessed using z-tests (p &lt; 0.05). Results: Taste was most commonly rated by CRG as very or extremely important in household food purchasing (87%). Availability, price, ingredients and nutritional value were also important to at least two-thirds of CRG. Taste was similarly important to LIG (85%), but they were more likely to rate price and less likely to rate availability, nutritional value and ingredients as important. When prompted to choose the most important factor, price and taste were the most common responses, chosen by similar proportions of CRG, while price was the most important factor for LIG, followed by taste. CRG versus LIG were more likely to prioritize personal taste over cost, health and nutrition information on labels, buying local and selecting according to nutrition, brand and origin/sourcing information. CRG were less likely than LIG to prefer a lower cost and usually select according to price. LIG were more likely than CRG to state that nothing supports them in selecting healthier foods and less likely to have found support from good-tasting recipes, advance meal or grocery list preparation, cooking equipment access, following influencers, recommendations from organizations or consulting a dietitian/nutritionist. Conversely, LIG were more likely to identify price and availability as barriers to selecting healthier foods, and less likely to see long preparation time, small servings sizes or nothing as barriers. Conclusions: Cost is a strong barrier to healthy eating, especially with limited income, along with taste, while nutrition is not a leading influence on food choice. Strategies to enable healthy eating among low-income households must prioritize taste and cost.

Impact of the COVID-19 Pandemic on Changes in Consumer Purchasing Behavior in the Food Market with a Focus on Meat and Meat Products-A Comprehensive Literature Review.

The coronavirus has wreaked havoc on the global economy before the eyes of the entire world. Due to evolving consumer needs and expectations during the pandemic, the supply and demand for various goods and services varied from the pre-COVID-19 period. This article aims to understand the changes in purchasing and food choices, focusing particularly on meat and meat products, made by consumers and households in response to the crisis caused by the COVID-19 pandemic. The study also indicates the impact directions of these changes and assesses the magnitude of the contribution of various determinants that influenced them. The literature review from 2020 to 2023 was conducted using Scopus and the Web of Science scientific databases. The study identified sociodemographic and individual factors as the main determinants influencing consumers' purchasing or eating behavior. Positive shifts (e.g., implementing strategies to better manage food at home through activities like creating shopping lists, the average increase in consumer spending during store visits, and decrease in visit frequencies) or negative changes (e.g., shortages of food products in stores due to consumer panic buying, unusually high demand resulting from stockpiling, purchasing fewer fresh products, increased consumption of unhealthy foods and snacking, among other factors) during isolation were influenced by various individual factors (e.g., motivation, mental state) or sociodemographic factors (e.g., gender, age, income level, education). While individual factors had a greater impact on changes in consumer behavior in the early stages of the COVID-19 pandemic, socio-demographic factors became more important as the pandemic progressed.

Consumption of a variety of plant foods, ultra-processed foods, and risk for chronic disease: A dietary intervention

BackgroundThe reliance on ultra-processed foods (UPF) as a source of energy has increased over the last decade. Consumption of UPF is associated with increased calorie intake and increased risk for chronic disease. An intentional increase of a variety of non-ultra-processed plant foods may decrease UPF intake and reduce risk for chronic disease. MethodsThe objective of this study was to determine whether an intervention to increase in the number of varieties of non-ultra-processed plant foods consumed each week along with grocery reimbursement was associated with reduced intake of UPF and reduced risk of chronic disease. An 8-week dietary intervention with the intention for subjects (22 were recruited and started the study, while 19 subjects completed the study) to consume at least 30 varieties of non-ultra-processed plant foods per week was conducted. Subjects watched a weekly educational module, received recipes and grocery lists, and received reimbursement for non-ultra-processed plant foods that were purchased. Diet assessments were conducted by 24-h recall and 3-day diet records. Fasting plasma glucose, C-reactive protein, LDL and HDL cholesterol, and anthropomorphic measurements were assessed at four time points. ResultsThe number of different types of non-ultra-processed plant foods consumed each week was significantly increased after the 8-week intervention compared to before (34.7 ± 10.8 vs 23.1 ± 12.1; p < 0.001). The number of ultra-processed foods consumed per day was significantly lower during the intervention compared to the control period (5.32 ± 1.65 vs 6.54 ± 2.04; p = 0.02). There were no significant changes to biochemical or anthropomorphic following the 8-week intervention. DiscussionEducating individuals on the importance of the variety of plant foods intake along with reducing the financial barrier for purchasing plant foods may be an effective way to reduce reliance on ultra-processed foods. More research is needed to determine whether an increase in varieties of plant foods and reduction in ultra-processed food intake impacts risk for chronic disease.

Sparrow, and: This Is a Shopping List

Sparrow, and: This Is a Shopping List

Phase 2A Learnings Incorporated into RewinD-LB, a Phase 2B Clinical Trial of Neflamapimod in Dementia with Lewy Bodies

BackgroundIn an exploratory 91-participant phase 2a clinical trial (AscenD-LB, NCT04001517) in dementia with Lewy bodies (DLB), neflamapimod showed improvement over placebo on multiple clinical endpoints. To confirm those results, a phase 2b clinical study (RewinD-LB, NCT05869669 ) that is similar to AscenD-LB has been initiated.ObjectivesTo optimize the choice of patient population, primary endpoint, and biomarker evaluations in RewinD-LB.DesignEvaluation of the efficacy results from AscenD-LB, the main results of which, and a re-analysis after stratification for absence or presence of AD co-pathology (assessed by plasma ptau181), have been published. In addition, the MRI data from a prior phase 2a clinical trial in Early Alzheimer’s disease (AD), were reviewed.Setting22 clinical sites in the US and 2 in the Netherlands.ParticipantsProbable DLB by consensus criteria and abnormal dopamine uptake by DaTscan™ (Ioflupane I123 SPECT).InterventionNeflamapimod 40mg capsules or matching placebo capsules, twice-a-day (BID) or three-times-a-day (TID), for 16 weeks.Measurements6-test Neuropsychological Test Battery (NTB) assessing attention and executive function, Clinical Dementia Rating Sum-of-Boxes (CDR-SB), Timed Up and Go (TUG), International Shopping List Test (ISLT).ResultsWithin AscenD-LB, patients without evidence of AD co-pathology exhibited a neflamapimod treatment effect that was greater than that in the overall population and substantial (cohen’s d effect size vs. placebo ≥ for CDR-SB, TUG, Attention and ISLT-recognition). In addition, the CDR-SB and TUG performed better than the cognitive tests to demonstrate neflamapimod treatment effect in comparison to placebo. Further, clinical trial simulations indicate with 160-patients (randomized 1:1), RewinD-LB conducted in patients without AD co-pathology has >95% (approaching 100%) statistical power to detect significant improvement over placebo on the CDR-SB. Preliminary evidence of positive treatment effects on beta functional connectivity by EEG and basal forebrain atrophy by MRI were obtained in AscenD-LB and the Early AD study, respectively.ConclusionIn addition to use of a single dose regimen of neflamapimod (40mg TID), key distinctions between phase 2b and phase 2a include RewinD-LB (1) excluding patients with AD co-pathology, (2) having CDR-SB as the primary endpoint, and (3) having MRI studies to evaluate effects on basal forebrain atrophy.

Further Validation of a Self‐administered Smartphone‐based Verbal Learning and Memory Assessment

AbstractBackgroundThe International Shopping List test (ISLT) is a verbal word list learning test set within a realistic shopping list context, supporting ease of cultural adaptation, and addressing content validity and patient relevance. Improvements to and the wide adoption of natural language processing (NLP) software has enabled the possibility for self‐administered tests of verbal learning. LilaTM a self‐administered, smartphone‐application (app) was developed, using the virtual assistant and NLP. We have previously reported acceptability and usability data from qualitative analysis of concept elicitation interviews. We now seek to provide preliminary validation data around its use.MethodA convenience sample of healthy young adults (n = 40), M(SD)age = 35 (16), were invited to install and complete one assessment of the LilaTM app. A usability survey was also administered to explore participants’ experiences. The sample was predominantly female (70%) and of Asian ethnicity (62.5%). Data were collected in Australia, using an English word pool developed for the USA.ResultAcceptability was generally high with N = 38 completing immediate recall rounds and N = 32 completing the delayed recall round. Eight‐two percent found it extremely or somewhat easy to hear and understand what items were on the shopping list and 95% indicated that it was extremely or somewhat easy to understand what they had to do to complete the assessment. Scoring accuracy was 88% at the word item level, with reprocessing to address accent, context setting, and other NLP approaches to improve accuracy underway e.g., homophones biased to the grocery item.ConclusionWhilst acceptability was high, the importance of localization of test stimuli was confirmed as well as the need for additional data processing options to account for accent. Continued optimization of data processing to score participant responses and word item pools to reduce ambiguity is expected to further improve accuracy e.g., accounting for regional accents and consideration of homophones and compound words. However, specific characteristics of speech including in those for whom English may be a second/foreign language will be an area of focus for future development.

Further Validation of a Self‐administered Smartphone‐based Verbal Learning and Memory Assessment

AbstractBackgroundThe International Shopping List test (ISLT) is a verbal word list learning test set within a realistic shopping list context, supporting ease of cultural adaptation, and addressing content validity and patient relevance. Improvements to and the wide adoption of natural language processing (NLP) software has enabled the possibility for self‐administered tests of verbal learning. LilaTM a self‐administered, smartphone‐application (app) was developed, using the virtual assistant and NLP. We have previously reported acceptability and usability data from qualitative analysis of concept elicitation interviews. We now seek to provide preliminary validation data around its use.MethodA convenience sample of healthy young adults (n = 40), M(SD)age = 35 (16), were invited to install and complete one assessment of the LilaTM app. A usability survey was also administered to explore participants’ experiences. The sample was predominantly female (70%) and of Asian ethnicity (62.5%). Data were collected in Australia, using an English word pool developed for the USA.ResultAcceptability was generally high with N = 38 completing immediate recall rounds and N = 32 completing the delayed recall round. Eight‐two percent found it extremely or somewhat easy to hear and understand what items were on the shopping list and 95% indicated that it was extremely or somewhat easy to understand what they had to do to complete the assessment. Scoring accuracy was 88% at the word item level, with reprocessing to address accent, context setting, and other NLP approaches to improve accuracy underway e.g., homophones biased to the grocery item.ConclusionWhilst acceptability was high, the importance of localization of test stimuli was confirmed as well as the need for additional data processing options to account for accent. Continued optimization of data processing to score participant responses and word item pools to reduce ambiguity is expected to further improve accuracy e.g., accounting for regional accents and consideration of homophones and compound words. However, specific characteristics of speech including in those for whom English may be a second/foreign language will be an area of focus for future development.

Shopping Lists Increase Nutrition Quality of Foods Donated Through Food Drives

ABSTRACT During April and May 2022, four schools in rural southern Illinois hosted food drives to stock pantry shelves for summer. To test the efficacy of a brief intervention encouraging healthier donations, a random sample of foods from each drive was evaluated for nutrition quality. The Supporting Wellness at Pantries (SWAP) stoplight nutrition system was used to evaluate saturated fat, sodium, and sugar content of 1,157 foods. Results were positive with 35.2% of foods being categorized as green (choose often), 42% yellow (choose sometimes), and 22.7% red (choose rarely). No significant differences existed between drives. Providing shopping lists increases healthier donations.

SAT127 What’s Cookin’: Attitudes Towards A Healthy, Budget-friendly Meal Planning Tool In Patients With Type 2 Diabetes

Abstract Disclosure: R. Abramczyk: None. S. Sadiq: None. C. Vaz: None. Background: Eating home-cooked meals has been associated with reduced risk of developing type 2 diabetes (T2DM). Additionally, nutrition counseling can aid weight loss and improve glucose levels. However, these interventions may be less effective in underserved patients as food prices can be a barrier to healthy food access. We performed a preliminary assessment of a quality improvement nutritional intervention at a university-based clinic in a medically underserved area. Aim: This analysis aimed to measure patients’ perceived levels of confidence in shopping for and preparing healthy, DM-friendly meals and interest in receiving a sample grocery list with matching recipes. Methods: Patients with T2DM seen in fellows’ clinic over 3 months were offered surveys that measured confidence levels in shopping for and preparing a healthy, DM-friendly diet. Participants were subsequently offered an ADA-compliant, Supplemental Nutritional Assistance Program-friendly sample grocery list and weekly meal plan. Results: 50 patients completed surveys. 70% were &amp;gt;50 years and 70% identified as African American. 98% shop for food at a supermarket, with 12% also utilizing smaller grocery and corner stores. 8% were not confident in shopping for healthy, DM-friendly foods. 30% were somewhat confident, 46% were confident, and 16% were extremely confident in shopping for DM-friendly foods. 82% of participants either did their own meal prep at home or had someone else at home who cooked. 16% were not confident in cooking DM-friendly foods, whereas 26% were somewhat confident, 50% were confident, and 8% were extremely confident. 92% were interested in receiving a 1-week shopping list for healthy groceries with corresponding recipes. Conclusion: While many patients in a low socioeconomic status neighborhood reported feeling confident shopping for healthy, DM-friendly foods, fewer felt confident in preparing and cooking these foods. Most patients were interested in a budget friendly shopping list and meal planning tool to assist in both shopping for and cooking foods that will assist in achieving improved DM control. A follow up phase study will evaluate the rate of utilization and other patient behavioral factors in response to this intervention. Further research is needed to develop and evaluate the impact that tools such as this may have on changes in behavior towards shopping for and cooking healthy, DM-friendly foods at home and its effects on glycemic control. Presentation: Saturday, June 17, 2023

Association of Plasma Phosphorylated Tau With the Response to Neflamapimod Treatment in Patients With Dementia With Lewy Bodies.

In a proportion of patients, dementia with Lewy bodies (DLB) is associated with Alzheimer disease (AD) copathology, which is linked to accelerated cognitive decline and more extensive cortical atrophy. The objective was to evaluate the relationship between a biomarker of AD copathology, plasma tau phosphorylated at residue 181 (ptau181), and the treatment effects of the p38α kinase inhibitor neflamapimod, which targets the cholinergic degenerative process in DLB. The AscenD-LB study was a phase 2a, randomized (1:1), 16-week, placebo-controlled clinical trial of neflamapimod in DLB, the main results of which have been published. After the study was completed (i.e., post hoc), pretreatment plasma ptau181 levels were determined and participants were grouped based on a cutoff for AD pathology of 2.2 pg/mL (established in a separate cohort to identify AD from healthy controls). Clinical outcomes for the comparison of placebo with neflamapimod 40 mg three times daily (TID; the higher and more clinically active of 2 doses studied) were analyzed using mixed models for repeated measures within each subgroup (baseline plasma ptau181 < and ≥2.2 pg/mL). Pretreatment plasma ptau181 levels were determined in eighty-five participants with mild-to-moderate DLB receiving cholinesterase inhibitors, with 45 participants below and 40 above the 2.2 pg/mL cutoff at baseline. In the 16-week treatment period, in the comparison of placebo with neflamapimod 40 mg TID, for all end points evaluated, improvements with neflamapimod treatment were greater in participants below the cutoff, compared with those above the cutoff. In addition, participants below the ptau181 cutoff at baseline showed significant improvement over placebo in an attention composite measure (+0.42, 95% CI 0.07-0.78, p = 0.023, d = 0.78), the Clinical Dementia Rating Scale Sum of Boxes (-0.60, 95% CI -1.04 to -0.06, p = 0.031, d = 0.70), the Timed Up and Go test (-3.1 seconds, 95% CI -4.7 to -1.6, p < 0.001, d = 0.74), and International Shopping List Test-Recognition (+1.4, 95% CI 0.2-2.5, p = 0.024, d = 1.00). Exclusion of patients with elevated plasma ptau181, potentially through excluding patients with extensive cortical neurodegeneration, enriches for a patient with DLB population that is more responsive to neflamapimod. More generally, plasma biomarkers of AD copathology at study entry should be considered as stratification variables in DLB clinical trials. NCT04001517 at ClinicalTrials.gov.

Types of E-Consumers and Their Implications for Sustainable Consumption—A Study of the Behavior of Polish E-Consumers in the Second Decade of the 21st Century

This article is based on the findings of a longitudinal study examining the behavior of Polish e-consumers. A series of methodically planned and executed surveys was conducted to elucidate the evolution of online consumer behavior over the past decade. The objective of this article is to diagnose changes in the behavior of selected types of e-consumers from Generations X and Y over the last decade, and link them to the concept of sustainable consumption. The 2020 study employed a sample possessing attributes similar to the 2010 research study, maintaining the sample distribution in terms of gender, education, and age. Characterizations of the identified consumer types were derived from prevalent psychographic traits, attitudes towards oneself and others, behavioral patterns, and determinants of buying behavior. Four distinct types of Polish e-consumers were identified: HQ_type (those seeking the Highest Quality products), MS_type (those intending to Save Money during shopping), LT_type (those dedicating the Least amount of Time to shopping), and DP_type (those Deriving Pleasure from the shopping experience). The identified Polish e-consumer types were subjected to a comparative analysis spanning a decade. The findings reveal significant alterations in the behavior of e-consumers representing various types, with a trend favoring sustainable consumption. Generally, Polish e-consumers are shown to demonstrate conscious and sustainable consumption behaviors, such as effective financial management, especially evident in the MS_type group. They typically purchase products within their means, avoiding expensive credits to fulfill their “needs.” Half of the HQ_type, MS_type, and LT_type e-consumers recognize the importance of budgeting and spending tracking for informed consumption, whereas the DP_type, who enjoy shopping, tend to overlook active financial management, perceiving it as a burdensome task. Over the years, a positive shift in the HQ_type’s attitude towards spending management has been observed. A significant aspect of conscious and sustainable consumption involves planned purchases. More than half of the HQ_type, MS_type, and LT_type e-consumers adhere to ready-made shopping lists, while the more impulsive DP_type frequently opts to shop in-store without any preceding planning. This research carries both theoretical and practical implications. The repeatability of the studies renders them a fundamental source of knowledge about the studied populations over time, and serves as an exclusive means of learning about changes in market phenomena and processes in a scientific manner. The findings of this article may prove valuable for e-commerce managers in devising strategies for effective sales promotion and customer communication for different types of e-consumers.