Shenqi Fuzheng Injection Research Articles

Clinical study on treatment of malignant neoplasms with Shenqi Fuzheng Injection and chemotherapy

Clinical study on treatment of malignant neoplasms with Shenqi Fuzheng Injection and chemotherapy

Effects of Shenqi Fuzheng injection on changes of matrix metalloproteinases in patients with acute myocardial infarction

Objective: To investigate the effects of Shenqi Fuzheng injection SQFZI) on ventricular remodeling (VR) after acute myocardial infarction (AMI).Methods: Sixty patients with AMI were randomly divided into two groups and received conventional therapy and conventional therapy plus SQFZI separately. Matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-9 (TIMP-9) in plasma was measured on the 1st and 14th days after AMI.Results:MMP-9 andMMP-9/TIMP-9 were increased after AMI, after 2-week treatment, the level ofMMP-9 andMMP-9/TIMP-9 decreased more significantly in SQFZI group than that in the conventional group (P<0.05).Conclusion; Early treatment with SQFZI after AMI could reduce the level of MMPs and the production of collagen. It may be useful for the prevention of VR and heart failure after AMI.

Clinical observation on effect of Shenqi Fuzheng injection combined with chemotherapy in treating post-operational patients with colorectal carcinoma

Chemotherapy (CT) is the most important therapeutic means in treating post-operational patients with colorectal carcinoma (CA) , but its efficacy is often affected by the toxic side-effects of CT agents. TCM could reinforce body resistance and tonify the qi, alleviate the toxic side-effects of CT, thus strengthening the efficacy of organism against tumor. Shenqi Fuzheng ( ~ ~ JE, SQFZ) injection manufactured by Limin Pharmaceutical Factory of Livzon Group was used in treating 69 patients with post-operational colorectal CA in the surgical department of our hospital from October, 1999 to September, 2000, and with the simple CT group of 63 cases as the control. The difference of reaction during the period of CT and the 2-year relapse rate after therapy was observed and is now reported as follows.