Social scientists have long been interested in the varying responses to a specific intervention, motivating the enterprise of heterogeneous treatment effects (HTE) analysis. Over the past five decades, the rapid development of HTE methods, from conventional multiplicative interactions in linear models to explorations based on machine learning techniques, has been witnessed. This article presents a systematic review of major HTE methods, including multiplicative interaction modeling, generalized additive modeling, propensity-score-based methods, marginal treatment effect, separate LASSO constraints, causal trees, causal forests, Bayesian additive regression trees, and meta-learners (i.e., the S-learner, T-learner, X-learner, and R-learner). These methods, as described roughly in a chronological order to emphasize methodological developments, are addressed to highlight their respective strengths and limitations. Following an illustrative example, this article reflects on future methodological developments.
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