Methods Section Research Articles

Research on Construction Technology of Steel Structure Tie Rod Arch Bridge with Less Support

In order to explore the installation method of the steel box tie-rod arch bridge across the canal, in order to meet the requirements of rapid installation under the condition of near the existing diagonal bridge. Based on qingshuihe Bridge of G50 Shanghai-Chongqing Expressway, the installation technology of steel box pole arch bridge is studied by combining theoretical analysis and field practice. This paper analyzes the construction problem of Qingshuihe Bridge and proposes an construction method of small supports and large sections. The oblique asymmetric beam arch is designed to avoid the influence on the channel headband. The installation process of bridge deck system is optimized, the bending moment of steel beam is effectively reduced, and the temporary span of beam beam installation is improved. The finite element analysis shows that the beam, arch ribs and other components are in good stress condition according to the asymmetric deformation of the boom force, and ensure the smooth installation of the beam and bridge deck.

Jaringan Sekresi Pada Tanaman Dysoxylum parasiticum Osbeck (Meliaceae) di Mataram, Lombok

Dysoxylum parasiticum is a flowering plant from the Meliaceae family. This plant has a number of secondary metabolite compounds that have not been specifically identified at the anatomical and tissue level. The presence of secondary metabolite compounds can be identified through the presence of secretory tissue in plants. The aim of this research is to determine the structure, type and location of the secretory tissue in the stem and leaf organs. Preparations were made using the fresh preparation method, and slicing using the free-hand section method, with Tuloidine blue O 0.025% staining. The results show that the secretory tissue has an elongated channel structure like a lumen surrounded by epithelial cells. The location of the secretory tissue in the stem is evenly distributed in the cortex and pith, in the petiole of the leaf it is only found in the cotex, and in the leaf blade, the secretion ducts are found in the cortex of the midrib and the mesophyll of the leaf blade.

A Critical Review of Holistic Infection Control Practices in Healthcare Systems

The safety of patients and the general public has never been seriously doubted regarding infection control, especially in health facilities where nosocomial infections are still rampant. This critical review discusses comprehensive essential infection control concerns, including an evidence-based and multidimensional framework. Thus, presented in the literature and method sections, the outcomes focus on recent issues, ideas, and applications. It offers ideas about the effectiveness of adopting approaches to whole-person care to minimize the prevalence of infection and international compliance with quality healthcare. The result shows the importance of building stronger networks of effective systems against new emerging diseases.

Calculating and Reporting Coefficients of Variation for DIA-Based Proteomics.

The coefficient of variation (CV) is a measure that is frequently used to assess data dispersion for mass spectrometry-based proteomics. In the current era of burgeoning technical developments, there has been an increased focus on using CVs to measure the quantitative precision of new methods. Thus, it has also become important to define a set of guidelines on how to calculate and report the CVs. This perspective shows the effects that the CV equation, data normalization as well as software parameters, can have on data dispersion and CVs, highlighting the importance of reporting all these variables within the methods section. It also proposes a set of recommendations to calculate and report CVs for technical studies, where the main objective is to benchmark technical developments with a focus on precision. To assist in this process, a novel R package to calculate CVs (proteomicsCV) is also included.

Collocations in Methods Section of Masters of English Language Theses

Collocation has long been recognised as a problematic domain for Second language learners of English and acknowledged to lag far behind the acquisition of other Second language acquisition (SLA) aspects. This mixed approach study was, therefore, aimed to identify content words and their collocations in the methods section of the Master of Philosophy in English Language theses. Specifically, the research question was: What are the collocations of the content word in the Methods sections of English language MPhil theses at the University of Cape Coast, Ghana? The data was purposively sampled from 20 MPhil theses submitted to the Department of English and analysed using AntConc 3.5.8 software. The Firthian (1986) Collocation Approach was used for the study. The findings showed that the content word data is the keyword typical of the methods section, and it strongly collocates with both nouns and verbs to both the left and to the right in varied ways. Also, near-synonyms collocate differently with the keyword data. This study makes a vital contribution by revealing how the students in the Master of Philosophy in English programme make use of language to present the methods section of their theses. The study offers implications for engendering students’ academic writing, especially at the postgraduate level. Received: 18 September 2024 / Accepted: 10 November 2024 / Published: 20 November 2024

A novel method for calculating the ultimate bearing capacity of in-service RC arch bridges using sectional constitutive relation

Ultimate bearing capacity is the main basis for evaluating the safety state of in-service reinforced concrete (RC) arch bridges. However, current evaluation methods require a lot of cost to handle the material nonlinearity problem, thereby failing to efficiently addressing such a tough issue. To this end, a novel method for calculating the ultimate bearing capacity of in-service RC arch bridges is proposed. This method accelerates the material nonlinear analysis by the sectional constitutive relation, which avoids the computational intensiveness in conventional methods and may provide a quick solution for structural safety assessment. Firstly, considering the arch axis deviation, temperature change and arch rib damage, the geometric nonlinear differential equation is established, and the real internal force and deformation of the structure are obtained by spline function and Newton–Raphson method. On this basis, the sectional stiffness identification method of in-service arch bridges is developed, in which the identified stiffness is taken as the input parameter. Then, a practical formula of the sectional constitutive relation is proposed to accelerate the material nonlinear analysis based on the fiber model. Finally, the practical formula of the sectional constitutive relation is combined into the geometric nonlinear analysis of arch bridges, by which the double nonlinear analysis of in-service arch RC bridges is fast realized. The effectiveness and superiority of the proposed method is verified experimentally and numerically, and the main factors affecting the service safety of arch bridges are revealed through parameter analysis. The results show that the proposed method can improve the calculation efficiency significantly while maintaining the same accuracy as the traditional method. In numerical validation, the relative calculation error is only 2.08 %, and the total calculation time is only 1/25 of the finite element method.

Advanced Data Analytics and Machine Learning Driven Fraud Detection and Data Loss Prevention for Automated Incident Response in the US Healthcare Corporations

Fraud detection and data loss prevention are critical challenges facing US healthcare corporations as they strive to safeguard sensitive patient information and comply with stringent data protection regulations. The integration of advanced data analytics and machine learning has emerged as a powerful approach to enhance the efficiency and accuracy of detecting fraudulent activities and preventing data breaches. This study explores the application of machine learning-driven solutions in automating incident response for healthcare data security. The research begins by examining the current landscape of data analytics and machine learning in fraud detection, emphasizing the limitations of traditional methods. Through an extensive literature review and analysis of case studies within the US healthcare industry, the paper identifies key areas where advanced technologies can bridge existing gaps. The methods section outlines the data collection process, the machine learning algorithms implemented, and the evaluation metrics used to measure model performance. Results demonstrate the enhanced detection accuracy and prompt response capabilities of machine learning models compared to conventional techniques. The discussion delves into the implications of these findings, showcasing the transformative potential of automated incident response systems in reducing response times and mitigating data loss risks. Although promising, the study acknowledges limitations in data variability and model generalizability, suggesting avenues for further research. The paper concludes with strategic recommendations for adopting machine learning solutions in healthcare security protocols. By highlighting best practices and policy recommendations, this research aims to provide a roadmap for healthcare corporations seeking to strengthen their data protection frameworks. The insights presented underscore the pivotal role of advanced data analytics and machine learning in fortifying healthcare data security against evolving cyber threats.

Autism Transition to Adulthood Groups (ATAG): protocol for a feasibility RCT of a new peer-group intervention to promote successful transition to adulthood for autistic young people

IntroductionAutism is a lifelong neurodevelopmental condition diagnosed on the basis of differences in social communication, interaction and repetitive behaviours, including sensory sensitivities. Autistic individuals without intellectual disabilities often face barriers...

Retracted] Dual inhibition of COX‑2/5‑LOX blocks colon cancer proliferation, migration and invasion in vitro.

Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that there appeared to be a number of anomalies in the presentation of data, including both tabulated data and data in figures: First, a discrepancy was noted between the numbers of males and females reported in the Materials and methods section on p. 1681 (47 females and 47 males) and yet, in Table I, showing clinicopathological characteristics of the patients, different numbers of male and female patients were reported. Secondly, data in Fig. 1 on p. 1683 had been misassembled: Experiments with COX‑2 and 5‑LOX are shown, but the panels for the x40 and x100 magnified images are presented the wrong way around. Thirdly, regarding the western blotting data, there were a couple of instances where it appeared that different exposures of gels had been undertaken in an attempt to show the same data for different experimental conditions. Fourthly, western blotting data featured internally in Fig. 4C on p. 1686 appeared to be strikingly similar, such that the same data may have been used to show the results for differently performed experiments. Fifthly, the data shown in the left‑hand columns for the scratch‑wound assay experiments in Figs. 2A and 5A were the same, even though different experiments were intended to have been portrayed in these figures. Finally, after having conducted an independent investigation of this paper in the Editorial Office, the presence of overlapping sections was also noted comparing the Transwell cell invasion assay data in Figs. 3 and 5. Given the identification of these various issues in the paper, the Editor of Oncology Reports has decided that this article should be retracted from the Journal on account of the uncertainties, and an overall lack of confidence, in the presented data. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused. [Oncology Reports 35: 1680‑1688, 2016; DOI: 10.3892/or.2015.4506].

Circumstantial and tactic augmentation

Abstract The present study attempts to unveil patterns in interactive information structure of clause enhancement that conventionalize the actual representation of circumstantial elements which add information about time, place, manner, means, and reason/cause through circumstantial augmentation, tactic augmentation, or connectives in method sections of research articles (RAs). The dataset consisted of 120 method sections of randomly selected empirical RAs from ISI-indexed Q1-ranked applied linguistic journals published between 2020 and 2022. The results of the study point to a significant distinction in hypotactic augmentation to register circumstantial information in comparison to other choices available to authors. Moreover, the most striking observation to emerge from the data is that a logical information structure of circumstantial meaning is mostly facilitated through hypotactic non-finite enhancement rather than its finite counterpart. This viable preference lies in elliptical, evincing, and expressive functions of hypotactic clauses that make comprehension more attainable to the readers and assist authors in fulfilling the generic conventions and communicative purposes of academic writing and managing interactive information structures. A major theoretical implication of the current research entails the significance of the interactive functions of the options available to authors which can impose priorities on the system of choices within the context of information.

Optimizing Fundamental Frequencies in Axially Compressed Rotating Laminated Cylindrical Shells

Optimizing composite materials, particularly in rotating structures, offers several practical benefits in the mechanical engineering and aerospace engineering industries. Improved material configurations, such as optimal fiber orientations, enhance the structural performance by maximizing stiffness-to-weight ratios and reducing vibrations. This study optimized the fundamental frequencies of rotating laminated cylindrical shells using the golden section method with respect to fiber orientations. The investigation explored the impact of various factors such as end conditions, shell length, axial compressive force, rotating speed, and the size of the cutout on the maximum fundamental frequencies. Additionally, the associated vibration modes and optimal fiber orientations were demonstrated in relation to these influencing parameters. Generally, it was observed that the optimal frequency decreased with increasing length-to-radius ratio and compressive force.

SQSTS: A sequential procedure for estimating steady-state quantiles using standardized time series

ABSTRACT We develop and evaluate SQSTS, an automated sequential procedure for computing confidence intervals (CIs) for steady-state quantiles based on the simulation analysis methods of standardized time series (STS), batching, and sectioning. Using recent theoretical developments for STS-based quantile estimation in dependent sequences, we formulate the key steps in SQSTS for controlling the growth of the batch size on successive iterations of the procedure. The variance parameter associated with the full-sample quantile estimator is estimated by a combination of estimators that are asymptotically independent of each other and the full-sample quantile estimator with increasing batch size and a fixed number of batches. Extensive experimentation revealed that SQSTS performed well compared to its competitors in terms of estimated CI coverage probabilities; and it outperformed those competitors with regard to average sample-size requirements. Finally, we outline an extension of SQSTS for computing individual CIs for a set of selected quantiles.

Assessing the Prognostic Value of Cytoplasmic and Stromal Caveolin-1 in Early Triple-Negative Breast Cancer Undergoing Neoadjuvant Chemotherapy.

Triple-negative breast cancer (TNBC) is a highly aggressive subtype with limited therapeutic options, leading to higher relapse rates and mortality. Identifying prognostic biomarkers like caveolin-1 (CAV1) is crucial for personalized treatment. CAV1 influences tumor progression and chemotherapy response, particularly through its interaction with the tumor microenvironment (TME) and cancer metabolism. Understanding the prognostic value of CAV1 in different cellular compartments is essential for its clinical application in TNBC. In the methods section CAV1 gene expression in TNBC was evaluated using in silico analysis, followed by the immunohistochemical staining of tumor cytoplasm (cCAV1) and stromal cells (sCAV1) in 58 early-stage TNBC patients. Statistical analyses were performed to correlate CAV1 expression with clinicopathological features and survival. In the results section, in silico analysis revealed higher CAV1 expression in TNBC, correlating with shorter overall survival. In the patient samples, cCAV1 was observed in 10.3% of cases, and was associated with larger tumors, higher grades, and poorer prognoses. sCAV1 was detected in 42% of cases, associated with less proliferative and less aggressive tumors, but did not significantly impact prognoses. In conclusion, cCAV1 expression is a significant prognostic marker in early-stage TNBC, highlighting the importance of assessing CAV1 in different cellular compartments. Further research is needed to explore the mechanisms and clinical implications of cCAV1.

Research Article Abstracts in Management Sciences Written by Thai EFL Scholars: An Analysis of Rhetorical Moves, Verb Tenses and Voices

Research article (RA) abstracts play a critical role in disseminating research findings, particularly challenging for non-native English speakers. While prior studies have explored the move analysis of RA abstracts across various subjects, the management sciences—a globally prominent field—have received less attention. This study addresses this gap by examining the rhetorical move patterns, verb tense usage, and voice constructions in 200 RA abstracts from Thai tier 1 management journals written by Thai scholars. The results showed that: 1) the Purpose-Method-Product structure was the most commonly employed move pattern; 2) present simple tense was mostly found in the Introduction, Purpose, and Conclusion sections, while past simple tense was preferred in the Method and Result sections; and 3) active voice was frequently used in the Introduction, Purpose, Product, and Conclusion sections, with a mix of active and passive voice mainly appearing in the Method section. The findings of the present study offer valuable insights for academic writing course developers, material designers, lecturers, and novice researchers, enhancing their understanding of RA abstract writing and supporting their integration into scientific communities.

Characterization of Contusive Spinal Cord Injury by Monitoring Motor-Evoked Potential.

The objective of the study is to characterize the onset and progression of contusive SCI over an eight-week period using a clinically applicable tool in an in vivo model. The background highlights the importance of a reliable and reproducible injury model and assessment tools for SCI. The methods section describes the experimental setup, including randomly assigned rats in three groups: Sham, Control, and Injury (undergoing a moderate contusive SCI using the NYU-Impactor). MEP monitoring and BBB examinations are conducted at baseline and weekly for eight weeks post-injury. The results indicate that the relative MEP power spectral decreased to 11% and 22% in the left and right hindlimbs, respectively, during the first week post-SCI. In the second week, a slight spontaneous recovery was observed, reaching 17% in the left and 31% in the right hindlimbs. Over the following four weeks post-SCI, continuing deterioration of MEP signal power was observed with no detectable recovery. SCI attenuates hindlimb MEP power spectral and reduces locomotion, though the changes in MEP and locomotion exhibit distinct temporal patterns. The MEP monitoring provides valuable insights into the functional integrity of motor pathways following SCI and offer a sensitive and reliable assessment. By implementing MEP monitoring, researchers can track the progression of SCI and evaluate the efficacy of therapeutic interventions quantitatively.

Factors Relationship with Fly Density Level in Telanaipura Subdistrict Temporary Waste Storage

Fly density is an indicator of environmental sanitation assessment. Fly density is influenced by waste management, the National Waste Management Information System (SIPSN) shows that waste generation in Jambi City reaches 159,688.01 tons/year. The aim of this research is to determine factors related to the level of fly density in Temporary Waste Storage Sites (TPSS) in Telanaipura District, Jambi City 2023. This research is a quantitative research with a cross sectional method research design. This research was conducted in the Telanaipura District community with a sample of 94 people. Data analysis was carried out using univariate and bivariate methods using correlation tests. The results of this study indicate that knowledge (p=0.027), action (p=0.029), monitoring (p=0.017), sorting (p=0.016), collection (p=0.027), and transportation (p=0.026) have relationship with the level of fly density, while attitude (p=0.245) had no relationship with the level of fly density. Knowledge, action, monitoring, sorting, collection and transportation are factors related to the level of fly density in temporary waste storage sites in Telanaipura District. It is hoped that the public will pay attention to managing household waste properly.

Indeks Massa Tubuh (IMT) dengan Kadar Hemoglobin Remaja Putri

Anemia is a condition experienced by the body when red blood cells have hemoglobin levels less than the normal limit (<12 gr/dl). Adolescent groups, especially young women, are susceptible to anemia because they menstruate every month. One of the factors causing anemia in adolescent girls is poor nutritional status. Wrong eating habits, such as being lazy about eating and liking to eat fast food instead of home-cooked food, cause insufficient nutrition, thus affecting the nutritional status of young women. The aim of this research is to determine the relationship between Body Mass Index (BMI) and hemoglobin levels in adolescent girls. This type of quantitative research uses a cross sectional method. The population is 406 young women from the Mamboro Community Health Center Area High School. The sample was 89 female students with a sampling technique, namely cluster random sampling. Data analysis uses the Chi Square test. The results of the study showed that the majority of young women with BMI were thin at 56.2% and there was a relationship between BMI and hemoglobin levels of young women with a P-Value of 0.000 <0.1. The conclusion of the study is that there is a relationship between BMI and hemoglobin levels in adolescent girls.

Indeks Massa Tubuh (IMT) dengan Kadar Hemoglobin Remaja Putri

Anemia is a condition experienced by the body when red blood cells have hemoglobin levels less than the normal limit (<12 gr/dl). Adolescent groups, especially young women, are susceptible to anemia because they menstruate every month. One of the factors causing anemia in adolescent girls is poor nutritional status. Wrong eating habits, such as being lazy about eating and liking to eat fast food instead of home-cooked food, cause insufficient nutrition, thus affecting the nutritional status of young women. The aim of this research is to determine the relationship between Body Mass Index (BMI) and hemoglobin levels in adolescent girls. This type of quantitative research uses a cross sectional method. The population is 406 young women from the Mamboro Community Health Center Area High School. The sample was 89 female students with a sampling technique, namely cluster random sampling. Data analysis uses the Chi Square test. The results of the study showed that the majority of young women with BMI were thin at 56.2% and there was a relationship between BMI and hemoglobin levels of young women with a P-Value of 0.000 <0.1. The conclusion of the study is that there is a relationship between BMI and hemoglobin levels in adolescent girls.

Obstetric Penicillin Allergy Evaluations

BackgroundPenicillin allergy is reported in 5-15% of the world population, with 3-10% of pregnant women reporting the same. However, more than 90% of these patients can tolerate penicillin after appropriate evaluation. Penicillin is indicated for various issues that arise in pregnancy, and a history of allergy can have negative individual and public health consequences. ObjectiveTo prospectively evaluate the feasibility, safety, and select obstetric outcomes of obstetric penicillin allergy evaluations arranged through a direct referral phone line from obstetric practices to an employed allergy/immunology practice. MethodsPatients were referred via direct phone line for evaluation during their antenatal visits between May 2019 and May 2022. Patients skin prick testing, and those with negative PST were given an amoxicillin challenge. In select cases, direct oral challenge was performed with a low-risk history. Data were analyzed using descriptive statistics. For detailed Methods, please see the Methods section in this article's Online Repository at www.jacionline.org ResultsOf the 324 patients referred between May 2019 to May 2022, 251 (77.5%) presented for in-office evaluations. 239/251 (95.2%) patients underwent penicillin skin testing followed by oral challenge if negative, 12 (4.8%) patients underwent direct challenge without skin testing, and all of them passed the challenge. Of the patients undergoing penicillin skin testing, 230 (97.2%) had negative skin testing and 229 tolerated subsequent oral amoxicillin doses, with 1 patient experiencing a delayed reaction to the amoxicillin. The patients who presented for evaluation had more people who lived in Zip codes that have been attributed to have high socioeconomic status, compared to the no-show group (73.7% vs 63.3%). ConclusionWe are the largest study to date to demonstrate the safety and feasibility of a phone line for obstetric penicillin allergy referrals. We demonstrate a better show rate than previous analyses, with most of these patients successfully de-labeled.

The evaluation of therapeutic outcomes of biologics in allergic fungal rhinosinusitis: a systematic review and meta-analysis.

Allergic fungal rhinosinusitis (AFRS) is a localized inflammatory, hypersensitivity reaction affecting the nasal cavity and its sinuses secondary to fungal colonization. The burden of surgical revisions and recurrence rates in this disease led to a recent hypothesized advancement in the medical management being experimented, which is the use of biologics. Therefore, this systematic review analyzed nine articles to highlight the significance of biologics in the management of AFRS through a comprehensive strategy, as seen in Supplementary Methods Section (1-9).