BackgroundNew graduate nurses are expected to have the clinical decision making (CDM) skills necessary to safely care for multiple patients with complex, competing needs. Limited opportunities to care for multiple patients in the clinical setting hinders the development of students’ CDM and clinical judgment abilities. This study aimed to ascertain the impact of commercially designed screen-based simulations (SBS) on students’ performance across CDM elements of the National Council for State Boards of Nursing (NCSBN) Clinical Judgment Measurement Model (CJMM). SampleThe purposive sample included 68 students enrolled in an adult medical-surgical course. MethodsA quasi-experimental posttest design was implemented by integrating two prioritization of care SBS across a semester (weeks four and nine) as part of required clinical hours. ResultsIncreases in intervention selection (p = .001, d = 0.404) and intervention prioritization (p = .012, d = 0.313), in less time (p = < .001, d = −0.763), were noted with a small to medium effect size. Decreases in level of care selection (p = .063, d = −0.229) and patient prioritization (p = .001, d = −0.440) were noted with a small to medium effect size. Trends were noted in overall score increases with a small effect size (p = .096, d = 0.204). ConclusionsStudy outcomes suggest that prelicensure nursing students need repetitive practice in multiple-patient triage and prioritization of care opportunities. Prelicensure coursework and direct care clinical experiences can be supplemented with targeted SBS to facilitate the development of all foundational components of CDM to help bridge the knowledge-to-practice gap.