Evolution Of Science Research Articles

Network Medicine as a Tool to Enhance Regenerative Rehabilitation Practice.

The aim of the study was to demonstrate the utility of network medicine for enhancing regenerative rehabilitation approaches. We employed a scientometric approach to illustrate the scientific evolution of regenerative rehabilitation and network medicine over the past 20 yrs. We then present two exemplars of a novel application of network medicine, first to optimize the development of a multimodal rehabilitation program for osteoarthritis and, second, to demonstrate the potential utility of a regenerative rehabilitation protocol for neurological applications. The scientometric analysis revealed thematic clusters guiding the fields of regenerative rehabilitation, while also revealing a notable gap in the integration of advanced computational biology tools, such as network medicine. To address this gap, we applied a network medicine paradigm as a proof-of-principle in rehabilitation, demonstrating its ability to predict previously known combinational benefits of a multimodal rehabilitation protocol for osteoarthritis and potential of a regenerative rehabilitation protocol to enhance outcomes after stroke. The trajectory of progress in regenerative rehabilitation has been defined by embracing new technologies and approaches. We propose that network medicine is a new frontier for the field. Toward the design of efficient and optimized clinical protocols, we anticipate that the network medicine paradigm may have broad applications in the field of rehabilitation, even beyond the examples presented here.

Scientific evolution of “Gender parity” concept as a key strategy for empowerment

Scientific evolution of “Gender parity” concept as a key strategy for empowerment

Scientific evolution from the definition of Hirschsprung disease to the present: a bibliometric analysis (1980-2023).

The primary objective of this study is to define the global productivity of Hirschsprung disease (HSCR), identify influential studies, determine research directions focused on both historical and contemporary perspectives. The study obtained 2816 articles published between 1980 and 2023 related to HSCR from the Web of Science database, and comprehensive bibliometric analysis were conducted. The top three most productive countries were the USA (n = 1283), China (n = 1167), and Japan (n = 587). The most productive institution was Université Paris Cité (n = 149), and the most productive author was Prem Puri (n = 99). The most frequently used keywords in the articles were enterocolitis (n = 191), enteric nervous system (n = 136), and transanal endorectal pull-through (n = 129). Academic interest in HSCR began in 1887-1888, significantly increased in 1948 and 1964, and reached its highest peak in 1994. The findings indicate that key topics such as enterocolitis, enteric nervous system, surgical techniques, and genetic factors have been prominent in HSCR research. Previous studies, which often focused on molecular and genetic mechanisms, have shifted towards clinical and surgical applications in the last decade. Factor analysis reveals the complexity and diversity of HSCR research, with various topics examined, including clinical features, surgical treatments, pathological findings, and genetic bases. This study presents a comprehensive bibliometric analysis of global research trends and future directions in Hirschsprung disease, revealing significant changes and developments in the study of the disease. The study provides an important contribution to the existing literature by detailing the historical development, main research topics, and thematic evolution of Hirschsprung disease research. The findings indicate that future research focus in Hirschsprung disease may increasingly prioritize innovative approaches, such as stem cell therapy, alongside clinical and surgical advancements. These advancements have the potential to enhance patient quality of life and guide future research strategies.

Mapping analysis of sixty-seven years of scientific evolution about the transgender population

Gender, traditionally treated in a dichotomous manner as male and female, does not encompass non-binary gender identities. One of the terms used to refer to a non-binary gender identity is transgender, which is employed in this study to investigate its strategic themes and thematic evolution. To achieve this, a bibliometric performance and network analysis (BPNA) was carried out using the existing data from the Web of Science database between 1954 and March 2021. A total of 23,471 articles were identified and included in the SciMAT software to conduct a bibliometric analysis, resulting in the visualization of the graph depicting the thematic evolution structure and the strategic diagram. This analysis highlights eight motor themes and a significant cross-cutting theme, which are discussed in depth. The results demonstrate the relationship between the transgender theme and gender, identity, sexual orientation, hormone therapy, and gender-affirming surgery. It is concluded that, despite the large number of associated research, some areas of study are still in their early stages, such as the inclusion of transgender people in the formal labor market and in the prison context. This opens up the field for further studies.

Human motivation is organized hierarchically, from proximal (means) to ultimate (ends).

Murayama and Jach raise a key problem in behavioral sciences, to which we suggest evolutionary science can provide a solution. We emphasize the role of adaptive mechanisms in shaping behavior and argue for the integration of hierarchical theories of goal-directed cognition and behavioral flexibility, in order to unravel the motivations behind actions that, in themselves, seem disconnected from adaptive goals.

Exploring the holobiont concept through a plant evolutionary experiment study

Exploring the holobiont concept through a plant evolutionary experiment study The evolutionary processes underlying interactions between hosts and their associated microbes remain a black box that biologists have long sought to illuminate. A major limitation has been the lack of knowledge about precise molecular events, which are now increasingly accessible through next-generation sequencing technologies. The ERC Starting Grant HoloE2Plant project leads the way in host-microbiome evolutionary studies, utilising fast-cycling B. rapa plants and synthetic microbial communities. By harnessing high-throughput sequencing, experimental coevolution and advanced modelling, it unravels plant-microbiome interactions under pathogen pressure across multiple plant generations. By validating the holobiont concept and identifying key genetic mechanisms, HoloE2Plant sets the stage for designing microbial consortia for biocontrol and biostimulation, advancing functional evolutionary science in service of agroecology.

Deciphering Aging, Genetic, and Epigenetic Heterogeneity in Cancer Evolution: Toward Personalized Precision Preventative Medicine

ABSTRACTBackgroundCancer's inherent ability to evolve presents significant challenges for its categorization and treatment. Cancer evolution is driven by genetic, epigenetic, and phenotypic diversity influenced by microenvironment changes. Aging plays a crucial role by altering the microenvironment and inducing substantial genetic and epigenetic heterogeneity within an individual's somatic cells even before cancer initiation.ObjectivesThis review highlights the clinical significance of epigenetic mechanisms in cancer evolution, focusing on hematopoietic and solid tumors. The review aims to explore opportunities for integrating evolutionary principles and data science into cancer research.MethodsThe review synthesizes recent advancements in omics technologies, single‐cell sequencing, and genetic barcoding to elucidate epigenetic mechanisms and aging's role in cancer evolution.ResultsEpigenetic mechanisms' high plasticity generates heritable phenotypic diversity, driving malignant evolution toward poor prognosis. Advances in single‐cell sequencing and genetic barcoding enable the precise detection and tracking of biomarkers, allowing early, personalized interventions. Incorporating data science into cancer research has the potential to map, predict, and prevent cancer evolution effectively.ConclusionUnderstanding cancer evolution through novel technologies and data analysis offers a proactive approach to cancer prevention and treatment. By predicting key evolutionary events and leveraging personalized strategies, patient outcomes can be improved, and healthcare burdens reduced, marking a transformative shift in oncology.

Immunological Poetics and Postcolonial Echoes: Traversing the Medical Narratives From T.S. Eliot to J.M. Coetzee

ABSTRACTThis article explores the intersection of immunological discourse and literary narrative through the works of T.S. Eliot and J.M. Coetzee. The paper examines the early twentieth‐century shift from holistic disease models to germ theory, paralleling this scientific evolution with Eliot's use of chemical metaphors in “Tradition and the Individual Talent.” Eliot's essay is analyzed alongside scientific insights from scholars like Michael Whitworth and Kevin Brazil, highlighting the blend of personal insight and historical awareness in poetic and scientific innovation. This analysis extends to Coetzee's Age of Iron, contrasting Eliot's impersonal poetics with Coetzee's nuanced exploration of cancer, apartheid, and racial and gendered bodies. Through an immunological lens, the paper delves into how literature can challenge canonical boundaries, advocate for inclusive narratives, and foster cross‐racial empathy. By drawing parallels between medical narratives and literary expressions of illness and identity, it proposes literature as a means to navigate and reconcile the divides between health, the body, and the postcolonial other.

2024: A Year of Quantum Progress

2024 has proven to be a significant year for a number of scientific and technological advancements. In this News and Views article we review briefly some of the relevant developments in the field of information, quantum computation, AI, biology and evolutionary sciences.

The development of the profession and education of Prosthetics and Orthotics in South Africa.

The history of a profession is valuable literature as it recognizes the noteworthy contributions of its forerunners and the scientific evolution from its earliest state. The purpose of this paper is to recount the historical developments in the profession of Prosthetics and Orthotics (P & O) in South Africa. An electronic literature search identified 54 Sabinet and 17,400 Google Scholar records. Key search words were "medical orthotics and prosthetics," "South Africa," and "history." The selection criteria of literature were accomplished in the subsequent 3 phases: (1) the title review, (2) the abstract review, and (3) the full-text review. The records were screened by all 3 authors. Records were excluded if they were unrelated to the history and/or development of P & O in South Africa, the history and development of other medical professions in South Africa, the historical development of P & O in other countries, the historical development of other medical professions of other countries, and records that were non-English. No peer-reviewed record was found describing the history of P & O in South Africa. Faced with the paucity of peer-reviewed evidence, the authors browsed Tshwane University of Technology, Durban University of Technology, and Walter Sisulu University websites to secure historical context. The analyses of these P & O training institutions websites provide a glimpse of the history of P & O in South Africa. The authors had identified the following areas noteworthy to be reported on (1) the historical account of the profession in South Africa, (2) the recognized tertiary training institutions, (3) the minimum admission criteria to South Africa P & O training institutions, and (4) regulatory and statutory bodies of the profession of P & O in South Africa.

Expanding the Diversity of Actinobacterial Tectiviridae: A Novel Genus from Microbacterium.

Six novel Microbacterium phages belonging to the Tectiviridae family were isolated using Microbacterium testaceum as a host. Phages MuffinTheCat, Badulia, DesireeRose, Bee17, SCoupsA, and LuzDeMundo were purified from environmental samples by students participating in the Science Education Alliance Phage Hunters Advancing Genomics and Evolutionary Science (SEA-PHAGES) program at Alliance University, New York. The phages have linear dsDNA genomes 15,438-15,636 bp with 112-120 bp inverted terminal repeats. Transmission electron microscopy (TEM) imaging analysis revealed that the six novel phages have six-sided icosahedral double-layered capsids with an internal lipid membrane that occasionally forms protruding nanotubules. Annotation analysis determined that the novel Microbacterium phages all have 32-34 protein-coding genes and no tRNAs. Like other Tectiviridae, the phage genomes are arranged into two segments and include three highly conserved family genes that encode a DNA polymerase, double jelly-roll major capsid protein, and packaging ATPase. Although the novel bacteriophages have 91.6 to 97.5% nucleotide sequence similarity to each other, they are at most 58% similar to previously characterized Tectiviridae genera. Consequently, these novel Microbacterium phages expand the diversity of the Tectiviridae family, and we propose they form the sixth genus, Zetatectivirus.

Review of Gary Clark, Carl Jung and the Evolutionary Sciences: A New Vision for Analytical Psychology. London and New York: Routledge, 2025

Abstract Carl Jung and the Evolutionary Sciences: A New Vision for Analytical Psychology by Gary Clark returns to the anthropological theories of Jung’s time to assess whether they, and those of Jung’s ideas informed by them, remain useful for contemporary Jungian research in light of more recent scientific advances. This essay presents Clark’s central claims, including his validation of Jung’s use of supposedly discredited evolutionary beliefs, and evaluates whether Clark’s project truly represents ‘a new vision for analytical psychology’.

A minőségi növekedés felé – a nemnövekedés értékelése

The concept of degrowth, which advocates for quantitatively more restrained economic growth, is much maligned in mainstream economics. The aim of this paper is to provide constructive critique for this theory promoting qualitative growth and to encourage in-depth professional dialogue. It points out that the current socio-economic configuration does not allow for the achievement of sustainable development, therefore a more radical shift towards quality growth is in order. It then critically reviews the concept of degrowth representing a shift towards qualitative growth. In doing so it highlights the concept’s shortcomings, the ambiguity of its nexus with capitalism and democracy, and the neglect of the relevant role of modern industrial policy. In addition to a narrow interpretation of the concept, the transdisciplinary nature of the degrowth transition is also explored, incorporating relevant aspects of evolutionary science, systems theory and neuroscience. Finally, five insights are elaborated that may catalyse a degrowth research agenda and a meaningful professional dialogue.

ВПЛИВ ЦИФРОВІЗАЦІЇ НА ФОРМУВАННЯ ЛЮДСЬКОГО КАПІТАЛУ: ВИКЛИКИ ТА МОЖЛИВОСТІ

The accelerated digitalization of socio-economic processes creates an unprecedented dialectical unity of challenges and opportunities in human capital formation, necessitating a rethinking of approaches to its development. The aim of the research. Theoretical and methodological substantiation of digitalization's impact on human capital formation through systematization of scientific views' evolution and development of an assessment matrix for enterprise digital maturity influence. The subject of the research. Processes of human capital formation and development in the context of digital transformation of economy and society. The methods of the research. The methodology is based on a dialectical approach to analyze the unity of digitalization challenges and opportunities, a systematic approach to examine digital maturity, comparative analysis of international experience, and a matrix approach to assess digital maturity impact. The hypothesis of the research. Enterprises with higher levels of digital maturity create a more favorable environment for human capital development through effective utilization of digital technologies. The statement of basic materials. The dialectical unity of digitalization challenges and opportunities has been revealed. The periodization of human capital concept evolution identified stages from economic resource to hybrid intelligence paradigm. The proposed matrix enabled identification of nine scenarios of interaction between digitalization level and human capital development. The originality and practical significance of the research. A matrix approach for evaluating the relationship between organizations' digital maturity and human capital development is proposed. The matrix serves as a practical tool for diagnostics and determining human capital development directions. Conclusions and perspectives of further research. The stages of human capital concept development have been established, and the necessity of a systematic approach to digital transformation management has been proven. Further research will focus on empirical verification of the matrix and development of methodological tools for assessing investment efficiency in digital competencies development

Mapping Scientific and Topic Evolution Around Lithium-Based Clean Energy Technologies: A Bibliometric Analysis

Mapping Scientific and Topic Evolution Around Lithium-Based Clean Energy Technologies: A Bibliometric Analysis

The cognitive and evolutionary science of behavioural modernity goes beyond material chronology.

Stibbard-Hawkes' taphonomic findings are valuable, and his call for caution warranted, but the hazards he raises are being mitigated by a multi-pronged approach; current research on behavioural/cognitive modernity is not based solely on material chronology. Theories synthesize data from archaeology, anthropology, psychology, neuroscience, and genetics, and predictions arising from these theories are tested with mathematical and agent-based models.

Artificial intelligence applied to early childhood education: A focus for educational research?

The study focuses on a currently emerging topic: artificial intelligence (AI). The impact of AI on the field of education is considerable. The possibilities and risks associated with its use are already well known, especially when the ethical and/or legal boundaries associated with it are crossed. However, the potential of AI as an emerging technology, in the field of education in general, and in early childhood education in particular, is yet to be realised. In this paper we consider what has occurred to date, and then focus the attention of researchers who have conducted studies in the field of early childhood education. To do this, we adopted a bibliometric study approach. This type of analysis has allowed us to consider the scientific activity carried out in the field of AI as applied in early childhood education. As we note throughout this paper, this type of analysis is highly valued among the scientific community as a way of assessing the quality, productivity and scientific evolution of a subject of study. It provides academics with valuable information about research conducted in a particular area. Following the recommendations of experts in the field, in this paper we not only address the volume of publications (quantity), but also assess other scientometric indicators that measure their quality. The results of this study then can make a significant contribution to the field of research and work in early childhood education in the face of the new challenges presented by today’s society.

Cooperative research and development projects: researchers’ motivations for participation and the benefits and barriers they encounter

Purpose Research and development (R&D) initiatives are fundamental for society to evolve in its social, economic, technological and environmental dimensions. This study aimed to provide a view of what motivates researchers to participate in such projects as well as the benefits and barriers they encounter when cooperating in R&D projects. Design/methodology/approach A qualitative methodology was adopted, within which a case study was conducted: R&D project “GreenHealth - Digital Strategies”. This initiative was based on leveraging biological assets to improve well-being and promote health. Data were obtained from 10 interviews with researchers and documentary analysis such as the project’s official website and social media accounts. Findings The content analysis led to the conclusion that the researchers’ motivations for participating in R&D projects were the opportunity to contribute to scientific and social evolution, the creation of knowledge and personal factors inherent to the participating researchers. The benefits they derived were related to creating and spreading knowledge, as well as financial incentives. Barriers to participation were related to management, communication, organisational culture, the COVID-19 pandemic. Practical implications From this study the research team members can understand the importance of cooperation between institutions, which illustrates the importance of creating and transferring knowledge. This study shows also that, in R&D projects, educational and health institutions access new knowledge, attract highly qualified personnel/researchers, establish networks and share financial risks. Originality/value The study’s innovation derives from its demonstration that an R&D project of this nature is important for several organisations to develop the conception and implementation of a long-term strategy centred on human beings and focused on the eco-sustainability of the affected regions.

An Evolutionary Psychology Perspective on Athletic Development and Performance: Differences Between Proximate and Ultimate Explanations.

Many areas of mainstream psychology have embraced the notions that understanding human behaviour can be improved by integrating developments from evolutionary science; however, evolutionary principles have not been as widely applied among sport researchers or practitioners, especially those examining athlete development and the psychology of competition and performance. In this paper, we discuss the distinction between ultimate and proximate explanations of psychological outcomes, and the relevance of this distinction for exploring issues related to skill acquisition and athlete development. We use three examples-deliberate practice, early sport play and sustained engagement-to highlight the benefits and challenges of applying evolutionary theories to sport contexts. Embracing our species' evolutionary history has the potential to inform ongoing debates in athlete development and performance, among other areas of sport science.

A bibliometric analysis on the effects of land use change on fire dynamics: current status and progress

Bibliometrics has been widely applied across various scientific domains as a valuable tool to assess scientific evolution and identify developmental trends. Fire ecology, an emerging field, represents a significant ecological and evolutionary force that regulates populations and communities across time and space. Consequently, studies on how anthropogenic land use changes have altered fire regimes are increasing. This study seeks to analyze the evolution, geographical distribution, and collaboration patterns of scientific knowledge to understand trends in the literature and the primary conceptual and methodological foundations underlying research on land use change impacts on fire dynamics. Using the SCOPUS database, we employed bibliometric tools to examine key descriptive patterns in the literature. Co-occurrence networks were applied to identify scientific advancements based on titles, abstracts, and keywords, while a detailed analysis of 10% of the most cited articles offered insight into prevalent methodologies. We identified 295 relevant publications, with the United States and Brazil leading the research, highlighting substantial cooperation between these two countries. Among the authors, Shimabukuro Y. was the most prolific. Remote Sensing was the predominant journal for publication. Analysis of co-occurrence networks and the most cited articles indicated extensive use of satellite data, with applications in mapping and monitoring burned areas and identifying factors driving the emergence and shifts in fire regimes.