Safe Complementary Therapy Research Articles

The efficacy and safety of Baduanjin exercise as complementary therapy for pain reduction and functional improvement in knee osteoarthritis: A meta-analysis of randomized controlled trials.

The efficacy and safety of Baduanjin exercise as complementary therapy for pain reduction and functional improvement in knee osteoarthritis: A meta-analysis of randomized controlled trials.

Effectiveness and safety of Arecae Semen compounds for patients with depression: a systematic review and meta-analysis

BackgroundArecae Semen is a traditional herbal medicine widely used in the medical service and food industry, but in recent years, the carcinogenesis of edible Arecae Semen chewing has aroused comprehensive attention, therefore it is necessary to evaluate its medicinal properties. Increasing evidence has shown that Arecae Semen Compounds (ASC) possess antidepressant ability. This study aimed to evaluate the effectiveness and safety of ASC in the treatment of depression.MethodsWe retrieved articles in eight databases from their inception to May 2024. Randomized controlled trials (RCTs) comparing the effects of ASC alone or combined with routine treatment in patients with depression were identified. The Cochrane risk of bias (ROB) tool (ROB 2) was used for assessing the ROB in the included trials. Grading of Recommendations Assessment, Development, and Evaluation (GRADE) was used to assess the certainty of the evidence for the review outcomes. The outcomes included Hamilton depression rating scale (HAMD) scores, depression-related symptoms, serum dopamine levels, and adverse events. Stata 14.0 was used for data analysis calculating standardized mean difference (SMD) for continuous outcomes and relative risk (RR) for binary outcomes, both with 95% confidence intervals (CI).ResultsNine RCTs involving 787 patients were included in this review. ASC lowered HAMD scores (SMD − 3.43, 95% CI − 5.24 to − 1.61; I2 = 95.2%, P < 0.001), alleviated depression-related symptoms, increased serum dopamine levels, and reduced the incidence of adverse events slightly (RR 0.18, 95% CI 0.04 to 0.77; I2 = 0, P = 0.775) compared with the control group. Publication bias might account for the asymmetrical presentation of funnel plots. Meta-regression analysis revealed that regarding HAMD scores, there was no significant relationship with duration, sample size, or treatment strategy. The evidence of the outcomes was of very low certainty.ConclusionsASC may achieve better therapeutic effects, alleviate depression-related symptoms with a lower incidence of adverse events, and provide a potentially effective and safe complementary therapy for patients with depression. However, the evidence is very uncertain so further researches are required to validate our results and explore clinical implications of Arecae Semen in depth.Systematic review registrationPROSPERO CRD42022361150.

The Effect of Intradialytic Aerobic Exercise on Dialysis Parameters and Fatigue in Hemodialysis Patients: A Non-randomized Interventional Study.

Introduction Hemodialysis is the standard treatment for end-stage renal disease. However, patients receiving hemodialysis can become less active as a result of treatment, resulting in the accumulation of waste products. Intradialytic exercise improves the clearance of urea and creatinine by opening up vascular beds. Materials and methods We conducted a non-randomized interventional study to evaluate the effect of intradialytic aerobic exercise on dialysis parameters and fatigue among 295 hemodialysis patients selected through consecutive sampling (control group, n=147; experimental group, n=148) from two tertiary care centers. Baseline data on background variables and pre-test dialysis parameters (e.g., blood urea, creatinine, potassium, and hemoglobin levels) were assessed in both groups. Following connection to the hemodialysis machine, participants in the experimental group engaged in 15 minutes of intradialytic aerobic exercise per two hours of dialysis for a total of eight weeks, besides receiving routine care, compared to those in the control group. Post-test dialysis parameters were assessed for both groups at the end of the eighth week. The collected data were analyzed and tabulated using SPSS (IRB Inc., Armonk, New York). Results Intradialytic exercise led to significant improvements in post-test blood urea, creatinine, and fatigue in the experimental group (p<0.001). However, post-test serum potassium and hemoglobin levels remained relatively unchanged. Conclusion This study demonstrates the benefits of intra-dialytic aerobic exercise as a safe complementary therapy for a large population of dialysis patients, leading to better patient outcomes.

Efficacy and Safety of Traditional Chinese Medicines as a Complementary Therapy Combined With Chemotherapy in the Treatment of Gastric Cancer: An Overview of Systematic Reviews and Meta-Analyses.

In China, traditional Chinese medicines (TCMs), as a complementary therapy combined with chemotherapy, is widely used in the treatment of gastric cancer (GC). In order to systematically evaluate and synthesize existing evidence to provide a scientific basis for the efficacy and safety of this complementary therapy, we present an overview of systematic reviews (SRs) and meta-analyses (MAs) on the topic of TCMs as a complementary therapy in combination with chemotherapy for the treatment of GC. SRs/MAs on TCMs combined with chemotherapy for GC were comprehensively searched in 8 databases. Methodological quality, risk of bias, reporting quality, and quality of evidence were assessed using the Assessment of Multiple Systematic Reviews 2 (AMSTAR-2), the Risk of Bias in Systematic (ROBIS) scale, the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 (PRISMA 2020), as well as the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system. Thirteen published SRs/MAs were included in our study. In terms of methodology, all SRs/MAs were considered to be of very low quality. Only 3 SRs/MAs has been assessed as low risk of bias. None of the SRs/MAs has been fully reported on the checklist. A total of 97 outcome indicators extracted from the included SRs/MAs were evaluated, and only 1 item was assessed as high quality. TCMs may be an effective and safe complementary therapy in combination with chemotherapy for the treatment of GC. However, this conclusion must be treated with caution as the quality of the evidence provided by SRs/MAs is generally low.

The Effect of Foot Massage Relaxation Techniques To Reduce Pain Level In Patients With Ventilator In ICU Cengkareng Hospital In 2022

Pain usualy experienced by patients on ventilator in the ICU. Efforts to reduce pain with foot massage done independently on the patient. Foot massage safe complementary therapy, providing relaxing effect, feeling comfortable and reducing pain. This study used quasi experiment research design with pre and post test control group design. The total sample of 40 respondents was divided into an intervention group 30 respondents were given foot massage once a day for 2 consecutive days, the control group was 10 respondents given analgesic therapy for 2 consecutive days. Post test pain scores 30 minutes after getting treatment on first and second days. Results showed that majority of the age group 46-55 years 30%, majority male 57%, 65% were suctioned, and body position changes 82%, there was difference in pre-test (p = 0.001) and post-test (p=0.007) the intervention group, there was difference in the level of pain after foot massage in the intervention group and the administration of analgesics the control group (p=0.000), there was effect of suctioning mucus (p=0.003), there was effect of changes in body position (p=0.008). This means that foot massage has effect reducing pain levels in patients. This study recommends the need for further research and foot massage one of independent nurse interventions in nursing care for patients with ventilatory pain.

A randomized trial on the effect of transcutaneous electrical nerve stimulator on glycemic control in patients with type 2 diabetes

Transcutaneous electrical nerve stimulator (TENS) has been demonstrated to be beneficial in glycemic control in animal models, but its application in humans has not been well studied. We randomly assigned 160 patients with type 2 diabetes on oral antidiabetic drugs 1:1 to the TENS study device (n = 81) and placebo (n = 79). 147 (92%) randomized participants (mean [SD] age 59 [10] years, 92 men [58%], mean [SD] baseline HbA1c level 8.1% [0.6%]) completed the trial. At week 20, HbA1c decreased from 8.1% to 7.9% in the TENS group (− 0.2% [95% CI − 0.4% to − 0.1%]) and from 8.1% to 7.8% in the placebo group (− 0.3% [95% CI − 0.5% to − 0.2%]) (P = 0.821). Glycemic variability, measured as mean amplitude of glycemic excursion (MAGE) at week 20 were significantly different in the TENS group vs. the placebo group (66 mg/dL [95% CI 58, 73] vs. 79 mg/dL [95% CI 72, 87]) (P = 0.009). Our study provides the clinical evidence for the first time in humans that TENS does not demonstrate a statistically significant HbA1c reduction. However, it is a safe complementary therapy to improve MAGE in patients with type 2 diabetes.

Pendidikan Kesehatan tentang Terapi Komplementer pada Masa Nifas

Complementary midwifery services are part of the application of complementary and alternative medicine in midwifery services. Complementary midwifery services are an option for midwives and women to reduce medical interventions during pregnancy and childbirth and the puerperium, and based on experience this is quite helpful. However, most of these therapies are not considered meaningful in conventional medicine. This is due to the scarcity of published clinical evidence and information regarding the effectiveness of complementary obstetric services in pregnancy, childbirth and the puerperium. The use of complementary therapies in the field of midwifery must be proven safe by research. Although traditional / complementary medicine is relatively safer, it does not mean that it does not pose a risk, for that mothers must have adequate knowledge about the use of safe complementary therapies during the postpartum period. This community service is carried out in the work area of the Putri Ayu Community Health Center with the largest target number of pregnant women, so it is hoped that the mother will get correct information about the use of complementary therapies during the postpartum period since pregnancy, so that mothers can leave harmful therapies and utilize complementary therapies appropriately.

Effects of nanocurcumin supplementation on T‐helper 17 cells inflammatory response in patients with Behcet’s disease: a randomized controlled trial

Objective Present research was performed to assess the effects of nanocurcumin supplementation on T‐helper 17 (Th17) cells inflammatory response in patients with Behcet’s disease (BD). Methods In this randomized double-blind, placebo-controlled trial, 36 BD subjects were randomly placed into two groups to take 80 mg/day nanocurcumin or placebo for eight weeks. Disease activity, frequency of Th17 cells and expression of related parameters including retinoic acid‐related orphan receptor γ (RORγt) transcription factor messenger RNA (mRNA), related microRNAs (miRNAs) such as miRNA-155, miRNA-181, and miRNA-326 as well as proinflammatory cytokines including interleukin (IL)‐17 and IL‐23 were evaluated. Results Thirty-two patients (17 in the nanocurcumin and 15 in the placebo groups) completed the trial. Number of Th17 cells decreased significantly in the nanocurcumin group compared to baseline (p = .012) and placebo (p = .047). Moreover, RORγt, IL‐17, IL‐23, miRNA-155, miRNA-181, and miRNA-326 mRNA expression decreased significantly in the nanocurcumin group compared with baseline (p = .004, p = .009, p < .001, p < .001, p < .001, p < .001, respectively) and placebo (p = .002, p = .021, p = .006, p = .035, p < .001, p = .017, respectively). Significant reductions in IL-17 and IL-23 were seen in nanocurcumin group compared with baseline (p = .017 and p = .015) and placebo (p = .047 and p = .048, respectively). Significant reduction in disease activity was observed in nanocurcumin group compared with placebo group (p = .035). Conclusion Nanocurcumin supplementation had favorable effects in improving inflammatory factors and disease activity in BD patients. Additional studies are warranted to suggest nanocurcumin as a safe complementary therapy in BD. Highlights Nanocurcumin supplementation decreased Th17 cells frequency significantly compared with baseline and placebo group. Nanocurcumin supplementation decreased mRNA expression of RORγt, IL‐17, IL‐23, miRNA-155, miRNA-181, and miRNA-326 significantly compared to baseline and placebo group. Nanocurcumin supplementation decreased cell supernatant IL-17 and IL-23 significantly compared to baseline and placebo group. Nanocurcumin supplementation decreased disease activity significantly compared to placebo group.

Impacts of mindfulness-based interventions in people undergoing hemodialysis: a systematic review.

Introduction:Chronic kidney disease (CKD) is a serious public health problem worldwide, leading to a series of physical and psychological comorbidities, in addition to costly treatments, lifestyle and dietary restrictions. There is evidence that mindfulness-based interventions (MBIs) offer complementary treatment for people with chronic illnesses, including CKD, with the aim of improving overall health, reducing side effects and treatment costs. This review aims to investigate the MBIs impact on people with CKD undergoing hemodialysis, and to identify the methodological quality of the current literature in order to support future studies.Methods:We ran searches in five databases (MEDLINE via PubMed, PsycINFO, Embase, Web of Science and Scopus) in July 2020. The papers were selected and evaluated by two reviewers independently, using predefined criteria, including the Cochrane Group's risk of bias tool and its recommendations (CRD42020192936).Results:Of the 175 studies found, 6 randomized controlled trials met the inclusion criteria, and ranged from 2014 to 2019. There were significant improvements in symptoms of anxiety, depression, self-efficacy, sleep quality, and quality of life (n=3) in the groups submitted to the intervention, in addition to physical measures such as blood pressure, heart rate and respiratory rate (n=1).Conclusions:MBIs can offer a promising and safe complementary therapy for people with CKD undergoing hemodialysis, acting on quality of life and physical aspects of the disease.

Moxibustion for Chronic Fatigue Syndrome: A Systematic Review and Meta-Analysis.

Objective This review aimed at systematically evaluating the efficacy and safety of moxibustion for chronic fatigue syndrome (CFS). Methods Relevant trials were searched in seven digital databases up to January 2021. After literature screening, data extraction, and literature quality evaluation, the included studies were meta-analyzed using RevMan 5.4 software. The evidence level was assessed using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE). Results Fifteen studies involving 1030 CFS participants were included. Meta-analyses showed a favorable effect of moxibustion on the total effective rate compared with acupuncture (OR = 4.58, 95%CI = [2.85, 7.35], P < 0.00001) and drugs (OR = 6.36, 95%CI = [3.48, 11.59], P < 0.00001). Moxibustion also appeared to significantly reduce fatigue severity measured by fatigue scale-14 (FS-14) (WMD = −2.20, 95% CI = [−3.16, −1.24], P < 0.00001) and fatigue assessment instrument (FAI) (WMD = −16.36, 95% CI = [−26.58, −6.14], P=0.002) compared with the control group. In addition, among the 15 included studies, only two studies reported adverse events related to moxibustion, and the symptoms were relatively mild. The quality of evidence based on the 15 included trials was assessed as moderate to very low. Conclusions Based on limited evidence, moxibustion might be an effective and safe complementary therapy for CFS, which can be recommended to manage CFS. Because of the limited level of evidence in this review, further high-quality trials are still needed to confirm these findings.

APPLICATIONOF BLUE COLOR THERAPY TO REDUCING STRESS LEVELS IN THE ELDERLY IN THE AREA PUSKESMAS ROWOSARI SEMARANG

Decreased physical abilities, the emergence of disease, and psychosocial changes are sources of stress in the elderly ehich can develop into depression and even suicide. Treatment with anti-depresant in the long run cause dangnerous side effects. Blue color therapy is a safe complementary therapy using electromagnetic radiation spectrum which produces a relaxing effect and reducing stress in the elderly This therapy is one of the non pharmacological therapies that can reduce stress levels in the elderly in the area of puskesmas rowosari semarang.the type of research used is descriptive method of case study approach. The subject used by 2 people with the criteria of being willing to be an opponent, no suffer from color blindness, elderly with mild to moderate stress levels, elderly who like the blue color. Measurement of stress levels using depresion anxiety stress scale (DASS42), interventions of blue color therapy for 7 consecutive days, the results of the analysis obtained by subject 1 decreased from 20 (moderate stress) to 14 (mild stress), subject II from 22 (moderate stress) to 16 (moderate stress). The result of the case studies concluded that there was a reduction in stress levels reaching 6 score DASS42. The application of blue color therapy is recomended as a nursing intervention in the management of reduced stress levels in the elderly.the application of blue therapy is effective in reducing stress in the elderly, so it is recomended as a nursing intervention in the management of reducing stress levels in the elderly

Pendidikan Kesehatan tentang Terapi Komplementer dalam Kehamilan

Complementary therapy in health care is a non-conventional treatment aimed at increasing the degree of public health. The terpi includes promotional, preventive, curative, and rehabilitative efforts that have proven their quality of safety, and effectiveness based on research and science (Evidence Based Medicine). In complementary therapy, the therapist treats various diseases or complaints using traditional techniques and is not done by surgery and drugs or pharmaceutical products, but by utilizing various types of therapy and herbs.The use of complementary therapies in the field of midwifery must be proven safe by research. Pregnant women are a group that is recommended to take advantage of complementary therapy or medicine in dealing with perceived complaints, because complementary therapy can avoid the side effects of conventional medicine and have great control over their own health. Although traditional / complementary medicine is relatively safer, it does not mean that it does not pose a risk, therefore pregnant women must have adequate knowledge about the use of safe complementary therapies during pregnancy.Health education on complementary therapies in pregnancy is provided by extension methods when pregnant women carry out motherhood classes in the working area of Puskesmas Putri Ayu, Jambi City. This activity was carried out in conjunction with the clinical practice of students of D III Midwifery Stikes Baiturrahim Jambi.

Efficacy of cinnamon patch treatment for alleviating symptoms of overactive bladder: A double-blind, randomized, placebo-controlled trial

Efficacy of cinnamon patch treatment for alleviating symptoms of overactive bladder: A double-blind, randomized, placebo-controlled trial

Safety and efficacy of Berberis integerrima root extract in patients with type 2 diabetes. A parallel intervention based triple blind clinical trial.

To evaluate the safety and efficacy of methanol extract of Berberis integerrima root on type 2 diabetes compared to metformin. In a parallel triple blind clinical trial, 80 type 2 diabetic patients,, were randomized into two groups (treated with Berberis integerrima root, 480mg (oral), compared to control group treated with metformin 1000mg daily). Efficacy was evaluated by fasting and prandial glucose and HbA1c and side effects confirmed by physical examination, biology and hematology tests and urinalysis on days 15, 45 and 90. They were followed for 3months. Two hundred and eighteen patients were recruited and 80 (55female and 25 male) patients randomized in two groups and 60 patient were analysed. The mean age of patients was 51.8 ± 9.3 and 46.5 ± 10 in the experimental (Berberis integerrima ) and control (metformin) groups respectively (P = 0.02). The mean HbA1c at baseline was 8.1 ± 1.6% and 7.9 ± 1.6% for B. integerrima and metformin group respectively (P = 0.53), and there was no significant difference between the two groups (7.5 vs. 7.2) after 3months (P = 0.34).Weight loss was observed in both groups compared to baseline.No adverse event led to preventing the study was reported. Berberis integerrima root not only was effective as much as metformin in reducing blood glucose and controlling type 2 diabetes but also, no specific side effect was reported (in short term).So, it might be an effective and safe complementary therapy in diabetic patients.Iranian Research and Clinical Trial (IRCT) registeration number; 201,207,191,774N5.Funding: Vice chancellor for research, Physiology Research Center of Kerman University of Medical Sciences and the Exir pharmaceutical company.

Yiqi Fumai Injection as an Adjuvant Therapy in Treating Chronic Heart Failure: A Meta-Analysis of 33 Randomized Controlled Trials.

Background Yiqi Fumai injection (YQFM) is a traditional Chinese medicine widely used for cardiovascular diseases in China. This systematic review aimed to evaluate whether YQFM could be an effective and safe complementary therapy for chronic heart failure (CHF). Methods Eight electronic literature databases were searched up to March 31, 2020. Randomized controlled trials (RCTs) comparing YQFM + conventional treatment with conventional treatment alone for CHF were included. The primary outcome was response to treatment, which was graded by improvements in heart function based on the New York Heart Association (NYHA) criteria, while the secondary outcomes included the left ventricular ejection fraction (LVEF), cardiac output, left ventricular end-systolic diameter (LVESD), amino-terminal pro-brain natriuretic peptide (NT-proBNP), 6-minute walk test performance (6MWT), quality of life (QoL) as assessed by the Minnesota Living with Heart Failure questionnaire, and adverse reactions. Data from individual RCTs were pooled by a random-effects meta-analysis with effect measures of proportional odds ratios (pORs) and 95% confidence intervals (95% CIs) for the ordinal outcomes and the mean difference (MD) and 95% CI for the continuous outcomes. Results In total, 33 RCTs involving 3070 patients with an overall moderate-to-high risk of bias were selected. The meta-analysis showed that compared with conventional treatment alone, YQFM plus conventional treatment had a significantly higher likelihood of improving the response to treatment (pOR 1.88, 95% CI 1.47 to 2.42, I2 = 0%). YQFM also significantly improved the LVEF (MD 5.53%, 95% CI 4.73 to 6.33, I2 = 82%), cardiac output (MD 0.32 L/min, 95% CI 0.19 to 0.45, I2 = 47%), and LVESD (MD −3.73 mm, 95% CI −5.51 to −1.95, I2 = 22%), reduced the NT-proBNP levels (MD −341.83 pg/mL, 95% CI −417.89 to −265.77, I2 = 88%), and improved the 6MWT (MD 61.86 m, 95% CI 45.05 to 78.67, I2 = 64%) and QoL (MD −9.82, 95% CI −14.17 to −5.46, I2 = 81%). No serious adverse events related to YQFM were reported. Conclusion Although limited by a moderate-to-high risk of bias, the current evidence suggests that YQFM as a complementary treatment significantly improves heart function and related indicators in patients with CHF. The clinical use of YQFM needs careful safety monitoring. Well-designed studies are still required to further evaluate the efficacy and safety of YQFM for CHF.

The Effects of a Fixed Combination of Berberis aristata and Silybum marianum on Dyslipidaemia - A Meta-analysis and Systematic Review.

A fixed combination of Berberis aristata and Silybum marianum (Berberol) has been used by patients with dyslipidaemia. The aim of the present meta-analysis was to systematically evaluate the efficacy and safety of a fixed combination of B. aristata and S. marianum (Berberol) on serum lipid levels compared to placebo in a meta-analysis based on randomised, controlled trials. The meta-analysis was reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement, using the PICO (patients, intervention, comparison, outcome) format, and it was registered in the International Prospective Register of Systematic Reviews. The Cochrane Central Register of Controlled Trials, PubMed, Embase, and Web of Science databases were searched for relevant studies. Placebo-controlled clinical studies involving adult patients with a condition of dyslipidaemia and receiving a fixed combination of B. aristata and S. marianum were included. Four randomised trials, including a total of 491 patients, were pooled in statistical analysis. According to the present meta-analysis, Berberol significantly lowered the low-density lipoprotein level, total cholesterol, fasting plasma glucose levels, and the Homeostatic Model Assessment index compared to placebo; however, its effects on the high-density lipoprotein level, triglyceride level, and body mass index were not statistically significant by the end of a 3-month treatment period. Berberol appeared to be safe, and it did not increase the levels of alanine transaminase, aspartate transaminase, and creatine kinase enzymes. Berberol is an effective and presumably safe complementary therapy for the treatment of dyslipidaemia; however, the evidence supporting its use is very limited. The optimum dose and duration of treatment are unclear. A comprehensive evaluation of efficacy and safety is required in further high-quality clinical studies involving larger patient populations.

The combination of hawthorn extract and camphor significantly increases blood pressure: A meta-analysis and systematic review

The combination of hawthorn extract and camphor significantly increases blood pressure: A meta-analysis and systematic review

Therapeutic body wraps (TBW) for treatment of severe injurious behaviour in children with autism spectrum disorder (ASD): A 3-month randomized controlled feasibility study.

IntroductionThe use of therapeutic body wraps (TBW) has been reported in small series or case reports, but has become controversial.ObjectivesThis is a feasibility, multicentre, randomized, controlled, open-label trial with blinded outcome assessment (PROBE design).SettingChildren with autism and severe-injurious behaviours (SIB) were enrolled from 13 specialized clinics.InterventionsDry-sheet TBW (DRY group) vs. wet-sheet TBW (WET group).Primary outcome measures3-month change in the Aberrant Behaviour Checklist irritability score (ABC-irritability) within per-protocol (PP) sample.ResultsFrom January 2008 to January 2015, we recruited 48 children (age range: 5.9 to 9.9 years, 78.1% male). Seven patients (4 in the DRY group, 3 in the WET group) were dropped from the study early and were excluded from PP analysis. At endpoint, ABC-irritability significantly improved in both groups (means (standard deviation) = -11.15 (8.05) in the DRY group and -10.57 (9.29) in the WET group), as did the other ABC scores and the Children Autism Rating scale score. However, there was no significant difference between groups. All but 5 patients were rated as much or very much improved. A repeated-measures analysis confirmed the significant improvement in ABC-irritability scores according to time (p < .0001), with no significant difference between the two groups (group effect: p = .55; interaction time x group: p = .27). Pooling both groups together, the mean 3-month change from baseline in ABC-irritability score was -10.90 (effect size = 1.59, p < .0001).ConclusionsWe found that feasibility was overall satisfactory with a slow recruitment rate and a rather good attrition rate. TBW was a safe complementary therapy in this population. There was no difference between wet and dry TBW at 3 months, and ABC-irritability significantly decreased with both wet and dry sheet TBW. To assess whether TBW may constitute an alternative to medication or behavioural intervention for treating SIB in ASD patients, a larger randomized comparative trial (e.g. TBW vs. antipsychotics) is warranted.Trial registrationClinicalTrials.gov NCT03164746.

Effect of Lavender Oil on Relieving Post Cesarean Incisional Pain

This study aimed to evaluate the effect of lavender oil on relieving post cesarean incisional pain.A Quasi-experimental design was adopted in the current study. Setting: The study was conducted at the postpartum unit in Sueze-Canal University Hospital during the period from October 2013 to January 2014. A sample of convenience including 100 mothers was divided into two groups (study and control). Three tools were used for data collection, general charecteristic questionnaire, Visual Analogue Scale (VAS) and Modified Johansson Pain-O-Meter (MJPOM). The study group inhaled lavender oil and the control group received placebo. Results of the study showed highly statistically significant differences in pain intensity between the groups understudy (p<0.001), lavender oil was more effective with educated mothers and multiparous mothers. Conclusion; Lavender oil is a successful and safe complementary therapy in reducing pain after cesarean section. Results of the current study recommended that dissemination of lavender oil to all maternity hospital all over Egypt and added inhaled lavender oil into nursing curriculum in Port-Said.

La définition de la maladie de Parkinson est-elle génétique ?

La définition de la maladie de Parkinson est-elle génétique ?