Role Of KI Research Articles

Musa paradisiaca extract as a corrosion inhibitor of steel. Role of KI as a synergistic additive

Musa paradisiaca extract as a corrosion inhibitor of steel. Role of KI as a synergistic additive

English

English

Is proliferative index (Ki-67) useful to stratify patients (pts) with G2 gastroenteropancreatic neuroendocrine tumors (GEP-NETs)? Clinicopathologic correlation.

255 Background: Grade 2 (G2) Neuroendocrine tumors (NETs), of the digestive tract is a heterogeneous group of tumors. Several treatment options including chemotherapy and target therapy are available, but there is a lack of prospective trials assessing the role of pronostic factors in this population. Aim(s): to analyze prognostic factors and clinical characteristics in a population of patients with G2 GEP-NETs. To determine the role of ki 67 in the stratification of G2 population. Methods: Study population was obtained from our prospective database (Argentum Group). Survival was estimated using the Kaplan-Meier method and compared between Ki-67 quartiles using the log-rank test. Value of Ki-67 to discriminate mortality was assesed with a ROC curve analysis Results: 144 pts were evaluated. Mean age 54.9, 46.7% male. 102 (70.8%) with metastatic disease, mainly hepatic in 97 pts. (67.4%). 67.9 % underwent surgery. 34% received chemotherapy, and 10.9% target therapy. Median Ki-67 value was 6 (IQR 4-10), ROC curve=0.62 (95% CI 0.53 a 0.72 p=0.021. cut-off: 6.5 (sensitivity 62.2%, specificity 57.7%). Median survival was 97, 67, 51 and 27 months according stratification by quartile (p.001), 45 events (31.7%). Conclusions: Our results suggest that in the heterogenous G2 GEP-NETs there are significant differences in survival. This study was underpowered to detect differences between Ki-67 quartiles, we detected that chemotherapy was mostly used in the higher quartiles.

Rethinking the Man-agement of Knowledge in Organisations

The purpose of this paper is to contribute to our understanding of knowledge integration and dis-integration by revealing some of the conditions that support or hinder the management of knowledge especially in relation to Knowledge Management interventions. For the purposes of this analysis knowledge integration (thereafter KI) is defined as the process by which disperse knowledge within a social context across individual actors, in social relations, in actions and artefacts and other repository mechanisms, is connected. The main purpose of KI is to support practical judgment (phronesis) especially when addressing competing priorities and tensions. In other words, KI needs to be understood not just for the scope it provides to support new possibilities to be explored through the connections made, thus fostering management innovations through the choices exercised and actions taken. This latter focus presents scope to understand the role of KI as a process of accounting for and accommodating the impacts of...

Catalytic activities and properties of Au(III)/Schiff-base complexes in methanol oxidative carbonylation

Several Au(III)/Schiff-base complexes were studied and proven to be effective catalysts for oxidative carbonylation of methanol to generate dimethyl carbonate (DMC). Effects of Schiff-base ligands, promoters, and promoter mole ratio to Au(III)/Schiff-base complexes on catalytic activity were studied. When the reaction was carried out at a methanol/Au(III) molar ratio of 5060:1, an [AuCl 2(phen)]Cl/KI (phen = 1,10-phenanthroline) ratio of 1:4, a CO/O 2 pressure of 2:1, and a temperature of 120 °C for 3 h, the conversion, selectivity, and TOF value of the model reaction were 10.8%, 98%, and 138.9 h −1, respectively. The catalyst was characterized by FTIR, UV–vis, 1H NMR, and cyclic voltammetry. The oxidation state of gold during the reaction and the role of KI were discussed using data on electrochemical experiments and ESI-MS. [AuI 2(phen)] + was considered an intermediate in the reaction. A plausible Au(III)/Au(I) catalytic cycle mechanism was proposed.

Potassium iodide-assisted polyol route synthesis of monodisperse silver nanospheres

Monodisperse silver nanospheres have been synthesised in high yield by a developed polyol process, in which silver nitrate (AgNO3) was reduced by ethylene glycol (EG) with the assistance of polyvinyl pyrrolidone (PVP) and potassium iodide (KI). Both the KI concentration and reaction temperature are crucial for the morphologies and diameter distribution of silver nanostructures. Transmission electron microscopy and X-ray diffraction have been employed to characterise silver nanoparticles. The role of KI for the formation of monodisperse silver nanospheres has been discussed by taking into account the formation of silver iodide (AgI) as seeds.

Ki: A Key to Transform the Century of Death to the Century of Life

This is my response to the commentary written by Mr James Flowers with the title of ‘What is Qi?’ in the issue 4 of Vol.3 (2006) of eCAM. I will explain my opinions regarding the importance of Ki research, philosophical aspects of Ki and a possible role of Ki now and in the future.

Potassium Iodide as a Thyroid Blocker—Three Mile Island to Today

The Three Mile Island (TMI) nuclear emergency in the U.S. in March 1979 marked the first occasion when use of potassium iodide (KI) was considered for thyroid blocking of the population in the vicinity of a potentially serious release of fission products from a nuclear power reactor. In face of a demand that could not be satisfied by commercial supplies of low-dose KI drug products from the U.S. pharmaceutical industry, the Food and Drug Administration directed the manufacture and stockpiling of sufficient quantities of saturated solution of potassium iodide (SSKI) to provide protection for one million people in the event of a large-scale release of radioiodines. Although the drug was not used, the experience of producing, stockpiling, and making ready for use a large quantity of the drug resulted in significant public policy, regulatory, and logistical issues. A number of these issues have been resolved through scientific debate and consensus, development of official guidance regarding the proper role of KI in nuclear emergencies, and the approval of New Drug Applications for KI products specifically intended for thyroid blocking in nuclear emergencies. Other issues regarding broad-scale implementation of the guidelines remain today. This paper traces the history of the development and implementation of the use of KI from pre-TMI to the present.