Congenital obstruction of the duodenum, first described by Calder (7) in 1733, was long considered a fatal malformation of the newborn and a subject merely of academic interest. In view of the rapid downhill course within a week or two after birth, the diagnosis was formerly made by the pathologist at the necropsy table. More recently, however, the condition has been recognized clinically and roentgenologically, and during the past decade surgical procedures have been carried out successfully (2, 5, 11,12, 13, 18, 19, 24, 25, 31, 38, 40, 43, 46, 48, 49). So far about three hundred cases have been recorded in the literature (32). Approximately fifty patients have been operated upon, one-half of whom survived. Due to improved methods, introduced by Ladd (29), Donovan (10), and their coworkers, the mortality rate has been still further reduced. In spite of these advances, however, the disorder has received but little attention in the roentgen literature (20, 26, 35, 44, 45). In this communication we shall report six cases of congenital duodenal obstruction and summarize the salient features from the literature. Report Of Cases Case 1: Atresia of First Portion of the Duodenum (French Hospital, Service of Dr. F. C. Holden). A newborn white male vomited persistently after each feeding, at first food, later blood-tinged and finally coffee-ground material. The stools contained only meconium. The patient died on the third day of life, having had no roentgen examination. At autopsy, the stomach and first portion of the duodenum were found to be greatly dilated, the latter forming a blind pouch. There were numerous submucosal hemorrhages. The second portion of the duodenum was completely separated and contained at its funnel-shaped apex the orifice of the common bile duct. The head of the pancreas was closely attached to this region. There was no abnormality of the gallbladder or extrahepatic bile ducts. The pathological diagnosis was congenital atresia of the first portion of the duodenum. Case 2: Duodenal Atresia at Ampulla with Anomalies of Pancreatic and Common Bile Ducts. Non-Rotation of Intestine (French Hospital, Service of Dr. F. C. Holden). A newborn white male vomited shortly after the first feeding and continuously thereafter. The stools contained only meconium. A roentgen study revealed a moderate dilatation of the stomach and proximal portion of the duodenum; no barium passed into the jejunum. The intestine contained no gas (Fig. 1). A diagnosis of congenital duodenal atresia was made, but when a laparotomy was performed, on the ninth day, only a non-rotation of the intestine was found. Death occurred five days later. At autopsy, the stomach appeared moderately dilated. The first portion of the duodenum formed a blind pouch with a small bulge through which the duct of Santorini emptied.
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