Matharu plots: a thought-provoking exercise that empowers us to explore global research and eliminate biases.

Abstract ObjectivesWhen formulating new strategies, contemporary analysts prioritize sustainability. Research in green analytical chemistry aims to replace hazardous reagents with eco-friendly alternatives and minimize waste generation. This study employed a comprehensive assessment of greenness evaluation tools. A newly validated RP-HPLC method was subsequently applied for the quantitative analysis of Telmisartan (TEL) and Atorvastatin calcium (ATV Ca) in both pure form and tablet formulation.MethodsThe analysis utilized an HPLC-UV Youngling Acme 9000 system with an Inertsil ODS RP column (250 × 4.6 mm, 5 μm), operating at 250 nm. The mobile phase, a 60:40 (v/v) blend of acetonitrile and phosphate buffer (pH 3.5), was delivered at 1.50 mL min−1 under isocratic conditions. Telmisartan (TEL) and Atorvastatin calcium (ATV Ca) showed retention times of 2.75 and 5.33 min, respectively.ResultsCalibration curves were developed to evaluate the linearity of TEL (10–100 μg mL−1) and ATV Ca (2.5–25 μg mL−1), showing a high R2 of 0.999. The LOD and LOQ for TEL were 0.41 μg mL−1 and 0.23 μg mL−1, while for ATV Ca, they were 1.246 μg mL−1 and 0.695 μg mL−1, with recoveries averaging 98.59%–99.95% and 99.57%–99.98%, respectively. Validation of the method was performed following ICH guidelines. Moreover, the greenness assessment of the HPLC method was assessed using the AES, NEMI, AGP, AGREE, ComplexMoGAPI, AMGS, and BAGI.ConclusionThis study validates the newly developed method and evaluates its environmental impact with multiple evaluation tools, confirming its eco-friendly nature, highlighting its potential as a responsible choice for analysing the mixture, especially in quality control labs and the pharmaceutical industry.

The acceleration of industrialization was a turning point in the development of the global economy. Social movements have revolutionized green chemistry since the 1940s and brought about changes in industrial positions and sustainable processes with breakthroughs in environmental effect and population and company awareness. The 12 principles of Green Chemistry were proposed by Paul Anastas and John Warner in the 1990s. These principles center on the reduction or elimination of harmful solvents from chemical analyses and processes, as well as the avoidance of residue production. The creation of analytical techniques, which gave rise to the field known as "Green Analytical Chemistry," is one of the most active areas of research and development in green chemistry. This paper describes the multifaceted effects of green chemistry on pharmaceutical analysts, the environment, the public, analysts, and companies. Every decision and mindset have an impact on the finished product as well as everything around it. This work also considers the future of green chemistry, our future, and the environment.

Retraction notice to “Recent advances in polymer hydrogel nanoarchitectures and applications" [Current Research in Green and Sustainable Chemistry 4 (2021) 100143

Green chemistry is an approach to the design , manufacture and use of chemical products to internationally reduce or eliminate chemical hazards . it focuses on the reduction, recycling/ eliminations of the use of toxic and hazardous chemicals in production processes by finding creative , alternative routes for making the desired products that manimize the impact on the environment sustainable economic growth requires safe, sustainable resources for industrial production . This article describes an introductory account of the basic tanets on which the concept of the green chemistry is based . Green chemistry which is the latest and one of the most researched topic now days has been in demand since 1990's . Majority of research in green chemistry aims to reduce the energy consumption required for the production of desired products whether it may be any drug , dyes and other chemical compound. It aims to reduce or even eliminates the production of any harmful bio-product and maximizing the desired products without compromising with the environment . The goal of green chemistry (GC) is the design (or redesign) of product and manufacturing processes to reduce their impact on human health and the environment. Fundamental to the GC concept is the idea of sustainability _ reducing environment impacts and conserving natural resources for future Green generation . Although many of the principales of green chemistry are not new , the extend to which they have been organized into a coherent approach and the degree to which they are being applied have resulted in an intensified attention on this topic among the academic , industrial , and regulatory communities. The use of toxic, poisonous, hazardous and bio-accumalative chemical substance is reduced or eliminated in green chemistry , which involves the design of chemical processes and product. It is a fresh take on scientifically based environmental protection and in essential to preventing climate change , acid rain , and global warming . It's basic tenet increases efficacy , selectivity , and minimises waste creation , making it a crucial instrument in the fight against pollution

Green chemistry and responsible research and innovation: Moving beyond the 12 principles

Abstract Producing biomass‐derived chemicals to substitute their petrochemical counterparts has long been an aspiration of the green chemistry research community. However, synthesizing secondary amines from biomass precursors presents several challenges related to catalyst nature and the mechanistic understanding of reaction systems. Here, we unravel the mechanistic and kinetic implications of the reductive amination of phenol with cyclohexylamine over Pd/C and Rh/C. A competitive Langmuir‐Hinshelwood reaction model well interpreted the kinetic data, suggesting that support‐metal interfaces serve as active sites for H2, ─NH2 and ═NH activation. The apparent activation energies for imine hydrogenation were 87.6 kJ mol−1 (Pd/C) and 34.5 kJ mol−1 (Rh/C), while ΔHads and ΔSads values confirmed the physicochemical consistency of the model. Moreover, the catalysts demonstrated their high stability to operate for several catalytic cycles, with minor activity losses due to metal leaching and partial sintering of Pd nanoparticles. Despite phenol reductive amination following similar mechanisms on Rh/C and Pd/C, they show differences in selectivity because the hydrogenation of imine is more efficient on Rh0 than on Pd0. This is the first mechanism‐oriented kinetic study for phenol reductive amination; thus, it provides valuable information for process design and scale‐up.

Everyday chemicals found in personal care products, cleaning products, plastics, and household items are increasingly recognized as contributors to a wide range of adverse health effects. Those chemicals include phthalates, parabens, bisphenol A (BPA), triclosan, synthetic fragrances, and flame retardants, many of which have been linked to endocrine disruption, neurodevelopmental disorders, reproductive toxicity, metabolic disorders, and some cancers. This review combines the results of contemporary toxicological and epidemiological research to provide a comprehensive overview of human exposure pathways, mechanisms of toxic action, and associated health risks. Special attention is paid to sensitive groups such as infants, children, pregnant women, and people with pre-existing disease, who are likely to be more affected by chronic exposure to low doses of these contaminants. The article also discusses international control policies such as the U.S. Toxic Substances Control Act (TSCA), the Food and Drug Administration’s Consumer Products Regulations, and the European Union’s REACH regulations. While some progress has been made in banning or restricting certain toxic chemicals, enforcement is still spotty, and thousands of chemicals are still used without proper safety assessments. Furthermore, shortcomings in the science base of regulations such as the failure to assess aggregate exposures and chemical combinations create formidable obstacles to protecting public health. To address these challenges, the review discusses alternative options, from natural and environmentally friendly consumer products to the importance of public education in reducing exposure. Proposed policy recommendations include adopting the precautionary principle, accelerating international harmonization, increasing green chemistry research funding, and expanding biomonitoring programs. Finally, this review emphasizes the urgent need for integrated, science-based strategies in chemical safety that integrate regulatory reform, public education, and industrial innovation to reduce the health risks of everyday chemicals and ensure long-term environmental and human health sustainability.

Spectroscopic study of wemple-didomenico empirical formula and taucs model to determine the optical band gap of dye-doped polymer based on chitosan: Common poppy dye as a novel approach to reduce the optical band gap of biopolymer

This study analyzes green chemistry research trends in chemistry education. This study used a quantitative bibliometric approach. The number of publications analyzed is 104 publication documents from 2019 – 2024. This research collects, processes, and filters information in Scopus journals and articles. Metadata results show that the distribution of publication frequency peaked in 2019, with 26 documents identified. The green chemistry research area is dominated by chemistry research (31.3%). The country with the most documents and the most productive in publishing green chemistry is the United States, with 30 papers identified. At the same time, Indonesia is ranked fifth as the most productive country in publishing green chemistry, with 10 documents identified. Canada ranked second with 17 papers, and Germany ranked third with 15 documents. The institutions that contributed the most came from Germany: the University of Bremen, with 11 papers 10.58%, and the University of Toronto with 8 documents (7.69%). The authors with the most citations are Chen Tse-Lun et al., with 245 citations. Meanwhile, when viewed from the number of documents published by the author, Eilks I. has 11 papers with a contribution of 4.91%. There are 5 clusters with the most popping keywords: green chemistry, human, and chemical reaction. Research and publications on this topic have been sparse in the past five years. Surveys and analyses of green chemistry literature are essential because tracking research trends in green chemistry in chemistry education is vital to directing the future.

Selective hydrolysis of traditional Chinese medicine residue into reducing sugars catalysed by sulfonated carbon catalyst and application of hydrolysate

Green chemistry has become an important technique for solving environmental problems in the chemical industry, with an aim of developing sustainable catalysts for eco-friendly industrial processes. This review considers recent advancements in green chemistry particularly regarding development and application of sustainable catalysts. The study examines different varieties of sustainable catalysts from renewable materials, mild and energy-saving operational conditions as well as minimizing waste and enhancing recyclability. Furthermore, it also discusses key industrial applications like ammonia and hydrogen peroxide production using more sustainable processes. In addition, there is a growing embrace of green chemistry principles across other areas such as fine chemicals and pharmaceuticals. Nonetheless, some significant challenges still exist including need for more generalized and scalable means of discovery and optimization of catalysts. The paper underscores that bridging academia and industry gaps is crucial to successfully adopting green chemistry research in industrial contexts. For instance, accelerated discovery and optimization of sustainable catalysts depend heavily on advancements in data-driven strategies such as high-throughput experimentation as well as computational modeling.

ACS awards first grants to drive research in green chemistry

Abstract Green chemistry involves designing environmentally benign processes that either reduce or eliminate the use and production of hazardous substances in the production of safe chemical products. It aims at minimising waste; eliminating costly treatments; minimising energy and resource consumption, and yielding safer products. On this background, it becomes imperative to promote and establish Green chemistry worldwide, especially in developing countries by incorporating it into school curricula, thus placing it at its core for sustainable development purposes. While Zimbabwe, a sub-Saharan country, has made positive strides in key research areas such as the design of new chemicals, catalysis, solvents, renewable materials, and feedstocks, it still faces some challenges that inhibit the successful inception of the concept of green chemistry. An overview that includes educational curriculum, grants and awards, research, infrastructure, and facilities established to promote green chemistry research and education; challenges currently being faced in implementing the approaches and principles in selected universities; the role played by government bodies, and the public in influencing the criteria to promote the green chemistry concept is given.

The study introduces a groundbreaking continuous system that combines an extruder and grinder to enable catalyst-free and solvent-free reactions under mild conditions. This temperature-controlled system facilitates the synthesis of highly functionalized chromenes, which have valuable applications in generating combinatorial libraries and complex target molecules. The newly developed mill extruder machine offers several advantages for industrial production on a large scale. It effectively reduces waste, saves energy, and enhances time efficiency. This system represents a significant advancement in the field, providing a new strategy for one-pot synthesis of various types of highly functionalized spirooxindoles and chromenes. Remarkably, these reactions can be accomplished within a short timeframe of 2–10 min, yielding impressive results of 75–98%. The results demonstrate superior performance compared to traditional reaction methods, making it an appealing tool and hotspot area of research in green chemistry.

This descriptive study conducted a bibliometric analysis to describe research trends in Green Chemistry literature. The secondary data used were 200 scientific publications on Green Chemistry published between 2020 and 2024. The analysis results show that Green Chemistry has a strong interest and a significant number of publications in the world of scientific research. The high average citations per researcher indicate the relevance and significance of the research in the scientific community as well as its relevance to responding to complex environmental and industrial challenges. The high average number of publications per researcher shows the great interest and continuous contribution of researchers in expanding knowledge about green chemistry. This emphasizes the importance of working together, communicating, and committing to sustainable research to address environmental and business issues. Some evidence of the impact and relevance of research in the scientific literature includes high h and g indices and significant average citations per year. Articles on green chemistry continue to attract the attention of the scientific community and make significant contributions to the advancement of our knowledge and understanding of the field. Recent trends show significant interest in elements such as process, leafe, and cooper, indicating the direction of the latest research and developments in green chemistry.

Green chemistry, also known as sustainable or environmentally benign chemistry, has emerged as a critical paradigm shift in the field of chemistry, with the primary objective of designing and implementing chemical processes and products that minimize environmental impacts. This review provides a comprehensive overview of the key principles, developments, and impacts of green chemistry. Review begins by discussing the fundamental principles of green chemistry, including the 12 principles established by Anastas and Warner, which serve as a foundational framework for sustainable chemical design. These principles emphasize the importance of waste prevention, the use of renewable feedstocks, and the reduction of toxicity in chemical processes. Subsequently, the review explores the significant developments and innovations in green chemistry, such as the design of more sustainable solvents, catalytic processes, and the application of nanotechnology. Green chemistry has not only led to the development of environmentally friendly alternatives but has also reduced the environmental footprint of established chemical processes. The environmental and societal impacts of green chemistry are discussed, highlighting how the adoption of sustainable practices has led to reduced energy consumption, decreased waste generation, and the mitigation of harmful emissions. The review also emphasizes the role of green chemistry in addressing global challenges, such as climate change and resource depletion. The review concludes by underscoring the importance of continued research and education in green chemistry to further promote its widespread adoption. It highlights the potential for green chemistry to contribute significantly to a sustainable and environmentally conscious future, where chemistry plays a pivotal role in addressing the complex challenges of our time.

Abstract: Advancement in green synthetic methodologies has brought a revolution in heterocyclic synthesis. Green synthesis has bypassed the classical procedures involving toxic/hazardous solvents or catalysts and improved the current environmental safety standards by many folds. Green chemistry research has continuously made significant contributions to the development of heterocyclic scaffolds both at laboratory and commercial scales. Researchers are continuously developing and exploring the principles of green chemistry for the development of novel therapeutic agents. Quinoxaline lies in the category of versatile heterocyclic motifs, which possesses a wide diversity in its derivatives as well as a broad profile of its therapeutic potential. In the past decades, many new green synthetic protocols have been developed and employed successfully for the synthesis of quinoxaline derivatives. These include the use of reusable nanocatalysts, polymers, various green solvents, tonsils, catalysts, water as a catalyst, microwave irradiation, ultrasonic waves, non-toxic metal catalysts, surfactants, etc. The present review focuses on various green synthetic procedures reported for quinoxalines along with the specializations and applications of the reactions.

This feature article summarises our recent contributions (2019-2023) in designing and developing a handful of promising organic transformations for accessing several diversely functionalised biologically relevant organic scaffolds, following the green chemistry principles, particularly focusing on the application of low-energy visible light, electrochemistry, ball-milling, ultrasound, and catalyst- and additive-free synthetic strategies.

Application of biotechnology in green chemistry research