Registration Committee Research Articles

Utilization of Exotic Plant Genetic Resources in Wheat Registered Germplasm

Utilization of Exotic Plant Genetic Resources in Wheat Registered Germplasm Genetic Resources (PGRs) are material of plant origin which are of value for present and future generations of human kind. Since times immemorial these resources are being collected and conserved for further utilization in crop improvement programmes. Countries are highly interdependent on these genetic resources including the diversity rich nations where the major food production is dependent on crops which have actually originated in other countries. Thus, PGRs are continually exchanged for use in developing better crop varieties, resistant to various pests and diseases and to improve quality, quantity and other valuable or desirable traits. This unique germplasm is provided soft protection and registered at ICARNational Bureau of Plant Genetic Resources since 1996 through the Plant Germplam Registration Committee. An analysis on the extent of utilization of exotic germplasm in for developing trait specific unique germplasm was done. To start with the data was analysed for wheat germplasm registered from year 1996-2014, and it was found that 75% of the exotic germplasm was used as parents for the lines which were registered at ICAR-NBPGR.. .

Prise en charge multidisciplinaire en réseau personnalisé de soins des patientes présentant des vulnérabilités psychiques : expérience du centre hospitalier de Valence

At the Valence hospital centre, patients presenting with mental vulnerability are cared for using the same process as medical risk pregnancies. This study is based on the early screening of medical conditions and psychological and social instability issues. Using guidance material (Simplified brochure on HAS guidance criteria, vulnerability score, screening for mental instability, early prenatal support, etc.), community healthcare professionals locate, guide and classify patients. The care pathway is verified by the registration committee, and the coordinating midwife, in association with the patient and the community healthcare professional, organises and schedules the appointments at the establishment. The complex files are coordinated by the pregnancy medical staff or network, or are taken up and assessed subsequently at morbidity and mortality reviews or case re-assignments. The multidisciplinary work, coordinated between the community and the hospital, provides security and consistency for both patients and professionals.

Clinicopathological characteristics and oncological outcomes in patients with renal cell carcinoma registered in 2007: The first large-scale multicenter study from the Cancer Registration Committee of the Japanese Urological Association.

To describe the clinicopathological features and oncological outcomes of renal cell carcinoma diagnosed in Japan in 2007, the results of the large-scale renal cell carcinoma registration study carried out by the Japanese Urological Association are reported. The renal cell carcinoma survey was carried out by the Japanese Urological Association in 2012 to register newly diagnosed renal cell carcinoma cases in 2007 from 340 institutions nationwide. The survey included clinicopathological details, such as sex, age, family history, past history, smoking history, body mass index, reason for diagnosis, TNM classification, stage, histopathology, treatment and clinical outcomes. A total of 3663 cases diagnosed in 2007 were registered in this renal cell carcinoma registry program from 340 institutions. A total of 15 patients with a final diagnosis of oncocytoma were excluded, and 3648 cases of renal cell carcinoma were analyzed to evaluate oncological outcomes. The patients' median age was 63.9 years (range 5.9-95.1 years). Clear cell renal cell carcinoma was the most common histological subtype (77.2%), followed by papillary (5.0%) and chromophobe (3.2%) renal cell carcinoma. The most common initial treatment was radical nephrectomy (72.6%), and the most common secondary treatment was cytokine therapy (13.1%). Five-year overall survival rates in stages I, II, III, and IV were 94.8%, 90.2%, 78.8% and 39.6%, respectively. The 5-year overall survival rates for clear cell, papillary and chromophobe renal cell carcinomas, and carcinoma of the collecting ducts of Bellini were 88.6%, 79.8%, 93.0% and 40.0%, respectively. The present report is the first nationwide large-scale study to describe the clinicopathological characteristics and oncological outcomes of patients with renal cell carcinoma in Japan. Oncological outcomes depend on the clinical stage and histological subtype. Further investigations will be required to show improved oncological outcomes in the molecular targeted therapy era using the results of the present study as a baseline.

Dissipation pattern and risk assessment of flubendiamide on chili at different agro-climatic conditions in India.

Dissipation pattern and risk assessment of flubendiamide and its metabolite (desiodo flubendiamide) on chili were studied at four different agro-climatic locations of India at the standard and double dose at 60 and 120ga.i. ha(-1) at 10days interval. Quantification of residues was done on a high-performance liquid chromatograph (HPLC) with a photo diode array detector. The limit of quantification (LOQ) of this method was found to be 0.01mgkg(-1) while limit of detection (LOD) being 0.003mgkg(-1). Residues of flubendiamide were found to be below the determination limit in 15days at both the dosages in all locations. Half-life of flubendiamide when applied at 60 and 120ga.i. ha(-1) ranged from 0.85 to 1.80 and from 0.95 to 2.79days, respectively. On the basis of data generated under the All India Network Project on Pesticide Residues, a preharvest interval (PHI) of 1day has been recommended and the flubendiamide 480 SC has been registered for use on chili in India by the Central Insecticide Board and Registration Committee, Ministry of Agriculture, Government of India. The maximum residue limit (MRL) of flubendiamide on chili has been fixed by the Food Safety Standard Authority of India, Ministry of Health and Family Welfare, Government of India, as 0.02μgg(-1) after its risk assessment.

Thomas Slingsby Duncombe, the ‘Member for All England’: Representing the Non-voter in the Chartist Decade

Building on new interest in the Chartists’ attempts to elect their own representatives to Parliament, this essay analyses the methods and strategies through which a Member of Parliament might adopt, and virtually represent, a non-voter constituency. While in many ways Thomas Slingsby Duncombe fits the mould of the gentleman leader in popular politics, unlike many other MPs whose careers briefly intersected with the agendas of the Chartists and other working people, Thomas Slingsby Duncombe explicitly called himself a Chartist. He served his non-voter constituency, Chartists and members of the working classes, by acting as the recognized conduit to Parliament for their petitions and ideas, by travelling the country participating in dialogic communication with non-voters, by maintaining a consistent voting record on issues of interest to the working classes, and, most intriguingly, by crossing class boundaries to serve as a physical representative to the National Central Registration and Election Committee ...

Annual report of organ procurement in Japan: report from the Registration Committee of the Japan Society for Transplantation (2015)

Annual report of organ procurement in Japan: report from the Registration Committee of the Japan Society for Transplantation (2015)

Evaluation of the Gulf Cooperation Council Centralized Procedure: The Way Forward.

The aim of the study was to evaluate the Gulf Cooperation Council (GCC) centralized regulatory review process. Regulatory review times-including submission and application dates for new active substances (NASs) and existing active substances (EASs) using a standardized template for the period of 2006 to 2010-were collected directly from the GCC office located in Riyadh, Saudi Arabia. A total of 413 products (96 NASs and 317 EASs) were approved during the period, with an overall significant increase in the EASs ( P < .001). The median approval times increased from 107 calendar days in 2006 to 265 in 2010 ( P < .001). The lowest approval time was for EASs submitted by the Gulf companies (134 days) and the longest for NASs submitted by international companies (346 days) ( P < .001). These data were also analyzed according to therapeutic classes and dosage forms. The results also showed that the lowest number (n = 16) approved during the period was in 2010, and this was due to a major regulatory change implementing the International Conference on Harmonisation product stability guideline for the region. The findings indicate that the delay and the wide range in approval times could be reduced by utilizing a standard assessment template for product review and the implementation of a clock stop system for company responses to questions from the GCC central registration committee. Furthermore, using information technology tools would speed up the registration process rather than the manual exchange of product registration files between the executive office and the member states.

Persistence and risk assessment of spiromesifen on tomato in India: a multilocational study

Supervised field trials were conducted at four different agro-climatic locations of India to evaluate the dissipation pattern and risk assessment of spiromesifen on tomato. Spiromesifen 240 SC was sprayed on tomato at 150 and 300g a.i. ha(-1). Samples of tomato fruits were drawn at 0, 1, 3, 5, 7, 10 and 15days after treatment and soil at 15days after treatment. Quantification of residues was done on gas chromatograph-mass spectrophotometer in selective ion monitoring mode in the mass range of 271-274 (m/z). The limit of quantification of the method was found to be 0.05mgkg(-1), while the limit of determination was 0.015mgkg(-1). Residues were found below the LOQ of 0.05mgkg(-1) in 10days at both the doses of application at all the locations. Spiromesifen dissipated with a half-life of 0.93-1.38days at the recommended rate of application and 1.04-1.34days at the double the rate of application. Residues of spiromesifen in soil were detectable level (<0.05mgkg(-1)) after 15days of treatment. A preharvest interval (PHI) of 1day has been recommended on tomato on the basis of data generated under All India Network Project on Pesticide Residues. Spiromesifen 240 SC has been registered for its use on tomato by Central Insecticide Board and Registration Committee, Ministry of Agriculture, Government of India. The maximum residue limit (MRL) of spiromesifen on tomato has been fixed by Food Safety Standard Authority of India, Ministry of Health and Family Welfare, Government of India as 0.3μg/g after its risk assessment.

Residual behavior and risk assessment of flubendiamide on tomato at different agro-climatic conditions in India.

Supervised field trials were conducted at four different agro-climatic zones in India to evaluate the dissipation pattern and risk assessment of flubendiamide on tomato. Flubendiamide 480 SC was sprayed on tomato at 48 and 96gactive ingredient (a.i.) ha(-1). Samples of tomato fruits were drawn at 0, 1, 3, 5, 7, 10, 15, and 20days after treatment. Quantification of residues was done on a high-performance liquid chromatography (HPLC) device with a photo diode array detector. The limit of quantification (LOQ) of this method was found to be 0.01mgkg(-1) while limit of detection (LOD) being 0.003mgkg(-1). Residues of flubendiamide were found below the determination limit of 0.01mgkg(-1) in 20days at both the dosages in all the locations. The half-life of flubendiamide at an application rate of 48ga.i. ha(-1) varied from 0.33 to 3.28days and at 48-g a.i. ranged from 1.21 to 3.00days. On the basis of data generated under the All India Network Project on Pesticide Residues, a preharvest interval (PHI) of 1day has been recommended, and the flubendiamide 480 SC has been registered for its use on tomato by the Central Insecticide Board and Registration Committee, Ministry of Agriculture, Government of India. The maximum residue limit (MRL) of flubendiamide on tomato has been fixed by the Ministry of Health and Family Welfare, Government of India under Food Safety Standard Authority of India, as 0.07μgg(-1) after its risk assessment.

80 years of Netherlands Society of Cardiology

80 years of Netherlands Society of Cardiology

Potential wild rose germplasm of Western Himalayas—Conservation, evaluation and registration

The untamed roses (Rosa moschata, R. cathayensis) growing in the Himalayan region of the country are unutilized and disappearing very fast due to various factors and need to be evaluated and conserved as important germplasm. Some distinct strains are expected from the natural population which may have potential to be utilized in the improvement of roses. Collection of distinct wild strains of roses was done for their domestication, evaluation, conservation and utilization on the basis of morphological characteristics, viz. colour, shape and size of the opening buds, flower type, i.e. single or double, size and vigour of the plants. Twenty one strains responded to the domestication process and were further evaluated for various traits. Significant variations were observed among the collected species and their strains for the evaluation parameters studied. Only four elite strains IHBT-WR-24, IHBT-WR-16, IHBT-WR-23 and IHBT-WR-21 belonging to four different species with desirable traits, viz. winter active growth, compatibility and flower production potential were identified in the present study as suitable wild rose germplasm. These strains were registered with Plant Germplasm Registration Committee, National Bureau of Plant Genetic Resources, New Delhi.

Safety evaluation of flubendiamide and its metabolites on cabbage and persistence in soil in different agroclimatic zones of India

Supervised field trials following good agricultural practices were conducted at the research farms of four agricultural universities located at four different agroclimatic zones of India to evaluate the persistence and dissipation of flubendiamide and its metabolite, des-iodo flubendiamide, on cabbage. Two spray applications of flubendiamide 480 SC of standard and double dose at the rate of 24 and 48 g a.i. ha(-1) were given to the crop at a 15-day interval, and the residues of flubendiamide 2 h after spray were found in the range of 0.107-0.33 and 0.20-0.49 mg kg(-1) at respective doses. Residue of des-iodo flubendiamide was not detected in any cabbage sample during study period. No residues were found in the soil samples collected from all treated fields after 15 days of application. On the basis of data generated under All India Network Project on Pesticide Residues, a preharvest interval (PHI) of 10 days has been recommended, and the flubendiamide 480 SC has been registered for its use on cabbage by Central Insecticide Board and Registration Committee, Ministry of Agriculture, Government of India. The maximum residue limit (MRL) of flubendiamide on cabbage has been fixed by the Ministry of Health and Family Welfare, Government of India, under Food Safety Standard Authority of India as 0.05 μg/g after its risk assessment.

Annual Report of Organ Procurement in Japan: Report from the Registration Committee of the Japan Society for Transplantation (2014)

Annual Report of Organ Procurement in Japan: Report from the Registration Committee of the Japan Society for Transplantation (2014)

Oncological outcomes of renal pelvic and ureteral cancer patients registered in 2005: The first large population report from the Cancer Registration Committee of the Japanese Urological Association

To describe the clinical and pathological characteristics and the outcomes of renal pelvic and ureteral cancer patients diagnosed in 2005 in Japan. In 2011, data were collected from renal pelvic and ureteral cancer patients diagnosed in 2005. A total of 1509 registered patients from 348 institutions were analyzed. Epidemiology and survival were analyzed based on each cancer location and on cancer multiplicity. The 5-year overall survival of the 1509 patients was estimated at 0.64. Open surgery was carried out in 409 renal pelvic cancer cases (66.9%) and 315 ureteral cancer cases (63.0%). The retroperitoneal approach was common, and lymph node dissection was carried out in approximately one-third of open surgery cases and one-fifth of laparoscopic cases. Approximately 60% of the operated unilateral renal pelvic or ureteral cancer was diagnosed as invasive, and just 14.6% was diagnosed as stage pTa. Distribution of the estimated worst tumor grade was significantly different for renal pelvic cancer and ureteral cancer. This article presents the first large population report of survival data in Japanese renal pelvic and ureteral cancer patients. In comparison with the Japanese bladder cancer database report in 1999-2001 from the Cancer Registration Committee of the Japanese Urological Association, the pathological characteristics of renal pelvic and ureteral cancer were diagnosed as aggressive.

پیشاهنگ، رقم جدید ارزن معمولی برای تولید علوفه قصیل در دوره زمانی کوتاه

Research was conducted during 1999 to 2009 to develop and introduce a new common millet (Panicum miliaceum) cultivar suitable for areas with short growing seasons in Iran. Several common millet populations collected from different locations of Iran were evaluated in research farm of Seed and Plant Improvement Institute in Karaj and based on yield, agronomic traits and tolerance to abiotic stresses such loding, 21 superior lines were selected. During years 2000 to 2009, these lines were evaluated in different research experiments in Karaj, Gorgan and Dezful and also in farmers fields in Yazd, Kerman and Zabol, finally a superior line coded as KCM7 was selected. Based on the results of these experiments, the new line was early maturing with high and stable fresh forage yield of 35.5 tha-1 and dry forage yield of 7.6 tha-1. The panicle length of KCM7 is 26.87 cm, its 1000 seed weight is 4.2 g with yellow color seeds and yield of 1.69 tha-1. Line KCM7 was officially introduced in 2009 by Seed and Plant Improvement Institute after approval of Seed Registration Committee of Agricultural Research, Education and Extension Organization with name of Pishahang as the first common millet cultivar in Iran.

2012 International Conference on Electromagnetics in Advanced Applications 2012 IEEE AP-S Topical Conference on Antennas and Propagation in Wireless Communications URSI Electromagnetic Environment and Interference Symposium

The fourteenth International Conference on Electromagnetics in Advanced Applications (ICEAA), the second IEEE AP-S Topical Conference on Antennas and Propagation in Wireless Communications (IEEE APWC), and the first Electromagnetic Environment and Interference Symposium (EEIS, organized by Commission E of URSI, the International Union of Radio Science) were held at Cape Town, South Africa, on September 2-7, 2012. ICEAA had the IEEE Antennas and Propagation Society, the Istituto Superiore Mario Boella, and the Torino Wireless Foundation as principal cosponsors, and the International Union of Radio Science (URSI) as a technical cosponsor. IEEE APWC was the first conference of the IEEE Antennas and Propagation Society held on the African continent. The three conferences shared common registration, organizing, and scientific committees; common venues, receptions, and banquet; and social events.

The domestic livestock resources of Turkey: inventory of pigeon groups and breeds with notes on breeder organizations

The pigeon is one species among the numerous domestic animal types that contribute to the economy of Turkey as food and work, and provide diversion and pleasure for the nation's people. Pigeons are kept at the household level, usually in small numbers, by many hundreds of thousands of Turkish families, yet they have been subject to little study. This paper collates much of the information available (almost all in the Turkish language) to provide a brief history of the bird in Turkey. An inventory of the nine groups and 72 breeds that have been identified is presented. Some of these breeds are international in status, some are widespread in Turkey and some have only local distribution; many breeds have synonyms which are used in their areas of distribution. There is little government or academic support for pigeon breeders. The private Pigeon Breeders Association of Turkey and the Turkish Pigeon Federation are umbrella organisations for a number of breed clubs. In an initial attempt to standardise the national pigeon genetic resources, two of the more widespread breeds have been registered with the Animal Breeds Registration Committee of the Ministry of Food, Agriculture and Livestock.

Clinicopathological features of young patients (&lt;35 years of age) with breast cancer in a Japanese Breast Cancer Society supported study

To clarify the clinicopathological features of breast cancer in young females, surveillance data of the Registration Committee of the Japanese Breast Cancer Society were analyzed. The clinicopathological characteristics were compared between young (<35) patients and non-young (≥35) patients among 109,617 records registered between 2004 and 2009. The numbers of young and non-young patients were 2,982 (2.7 %) and 106,295 (97.0 %), respectively. The young patients had more cases of a familial history of breast cancer, more subjective symptoms, fewer bilateral tumors, lower BMIs, larger tumors, more positive lymph nodes, fewer instances of an ER-positive status, more instances of an HER2-positive status, more triple-negative tumors and more advanced TNM stages. The young patients more frequently received neoadjuvant chemotherapy and breast-conserving therapy (BCT) compared with the non-young patients. Eighty percent of all patients received adjuvant therapy. The young patients were more frequently treated with chemotherapy, molecular targeted therapy and radiation therapy than the non-young patients. In this study, young patients with breast cancer were diagnosed at more advanced stages and had more endocrine-unresponsive tumors than non-young patients. Further prognostic analyses should be conducted in this cohort.

Annual Report of Organ Procurement in Japan: Report from the Registration Committee of the Japan Society for Transplantation (2013)

Annual Report of Organ Procurement in Japan: Report from the Registration Committee of the Japan Society for Transplantation (2013)

A proposal for creating a guideline for cancer registration of the fibromatosis, PEComa group, malignant lymphoma In Situ and dendritic cell tumors (III).

BackgroundUnderstanding the biologic behavior of a tumor is a prerequisite for tumor registration code assignment. The aim of this report was to propose appropriate behavior codes of the International Classification of Disease Oncology 3 (ICD-O3) to rare, yet pathologically interesting hematopoietic and soft tissue tumors.MethodsThe Study Group for Hematopathology, the Bone and Soft Tissue Pathology Study Group, and the Cancer Registration Committee prepared the questionnaire containing provisional behavior codes of selected diseases.ResultsIn situ lesions of mantle cell and follicular lymphomas, dendritic cell tumors, and neoplasms with perivascular epithelioid cell differentiation (PEComa), not otherwise specified were classified as malignant (-/3). The fibromatosis group, with the exception of lipofibromatosis, was proposed as benign (-/0). Lipofibromatosis and several diseases that belong to the PEComa group were proposed as uncertain malignant potential (-/1). For the hematologic and soft tissue tumors, 274 and 288 members of the Korean Society of Pathologists, respectively, provided opinions through questionnaire, and most responders showed agreement with the provisional behavior code proposed.ConclusionsThe determination of behavior codes for the rare diseases described in this study, especially those of the PEComa group or malignant lymphoma, could be viewed as impractical and premature, but this study provides the basis for future research on this topic.