Region Of Human Retina Research Articles

Region-and Age-dependent Variation in Susceptibility of the Human Retina to Lipid Peroxidation

Trephined buttons from the posterior central (including the macula) and four peripheral regions of human retina were subjected to in vitro lipid peroxidation initiated by Fe+2. There was an age-related increase in peroxidation in the retinal tissue from the posterior region (P = 0.0019), but not in tissues from any of the four peripheral retinal quadrants (collective P = 0.24). These results suggest that the posterior region of the human retina is susceptible to lipid peroxidation and that age is a factor.

Retinal induction in various regions of human retina.

By the method of electro-stimulation, retinal induction was measured at various parts of the human retina. 1. The magnitude of retinal induction was found greatest at about 10° from the fovea. This fact might be correlated with the psychological fact that color contrast can most easily be perceived in the para-foveal region of the retina. 2. Red and green lights were found more effective in producing retinal induction than yellow and blue lights. 3. In measurements of retinal induction two photic stimuli are used, i.e., a colored light preceding a white test light. The intensity of retinal induction was shown to be independent of the intensity and the duration of the white test light, but determined by those of the inducing colored light. This law holds good for both foveal and peripheral vision. The authors are indebted to Prof. K. Motokawa for his invaluable advice and encouragement.