Data centers are energy-intensive facilities, with over 95% of their total cooling load attributed to the heat generated by information technology equipment (ITE). Various energy-saving techniques have been employed to enhance data center efficiency and to reduce power usage effectiveness (PUE). Among these, economizers using outdoor air for cooling are the most effective for addressing year-round cooling demands. Despite the simplicity of the load composition, analyzing data center cooling systems involves dynamic considerations, such as weather conditions, system conditions, and economizer control. A PUE interpretation tool was specifically developed for use in data centers, aimed at addressing the simplicity of data center loads and the complexity of system analysis. The tool was verified through a comparison with results from DesignBuilder implementing the EnergyPlus algorithm. Using the developed tool, a comparative analysis of economizer strategies based on the PUE distribution was conducted, with the aim of reducing the PUE of data centers across various climatic zones. The inclusion of evaporative cooling (EC) further improved cooling efficiency, leading to reductions in PUE by approximately 0.02 to 0.05 in dry zones. Additionally, wet zones exhibited PUE reductions, ranging from approximately 0.03 to 0.07, with the implementation of indirect air-side economizer (IASE). Sensitivity and uncertainty analysis were further conducted. The computer room air handler (CRAH) supply temperature and CRAH temperature difference were the most influential factors affecting the annual PUE. For the direct air-side economizer (DASE) and DASE + EC systems, higher PUE uncertainty was observed in zones 1B, 3B, 4B, and 5B, showing ranges of 1.17–1.39 and 1.15–1.17, respectively. In the case of the IASE and IASE + EC systems, higher PUE uncertainty was noted in zones 0A, 0B, 1A, 1B, and 2A, with ranges of 1.22–1.43 and 1.17–1.43, respectively. The distinctive innovation of the tool developed in this study is characterized by its integration of specific features unique to data centers. It streamlines the computation of cooling loads, thus minimizing the burden of input, and delivers energy consumption data for data center cooling systems with a level of precision comparable to that of commercial dynamic energy analysis tools. It provides data center engineers with a valuable resource to identify optimal alternatives and system design conditions for data centers. This empowers them to make informed decisions based on energy efficiency enhancements, thereby strengthening their ability to improve energy efficiency.
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