Recyclable Polymer-supported Formate Research Articles

Simple and Efficient Reduction of Azides to Amines using Recyclable Polymer-Supported Formate and Zinc

Polymer supported formate in conjunction with commercial zinc dust provides a mild and efficient procedure for the reduction of organic azides to corresponding amines. A variety of alkyl and aryl azides were selectively reduced in high yield and purity at room temperature.

Transfer hydrogenation using recyclable polymer-supported formate (PSF): Efficient and chemoselective reduction of nitroarenes

Nitroarenes can be reduced in high yields to the corresponding anilines by transfer hydrogenation using a stable H-donor, polymer-supported formate (PSF) in combination with palladium acetate (catalytic). The reactions occur at 100-120 degrees C in dimethyl-formamide and the PSF can be recycled for at least three runs. The procedure is chemoselective for nitro group; ester, ketone, aldehyde, and halide substituents on aromatic ring remain unaffected.

Palladium‐Catalyzed Simple and Efficient Hydrogenative Cleavage of Azo Compounds Using Recyclable Polymer‐Supported Formate.

Palladium-catalyzed room temperature transfer hydrogenation of azo compounds using recyclable polymer-supported formate as the hydrogen donor produces corresponding amine(s) in excellent yields (88%–98%). This method was found to be highly facile with selectivity over a number of other functional groups such as halogen, alkene, nitrile, carbonyl, amide, methoxy, and hydroxyl.Key words: azo compounds, catalytic transfer hydrogenation, polymer-supported formate, 10% Pd-C, amines.

Clean and Efficient Hydrogenative Cleavage of Azo Compounds Using Polymer‐Supported Formate and Zinc.

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Polymer‐Supported Formate and Magnesium: An Efficient Transfer Hydrogenation System for the Facile Reduction of Azo Compounds.

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Simple and Efficient Reduction of Aromatic Nitro Compounds Using Recyclable Polymer‐Supported Formate and Magnesium.

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Transfer Hydrogenation of Aromatic Nitro Compounds Using Polymer‐Supported Formate and Pd‐C.

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Novel and Efficient Transfer Hydrogenolysis of Protected Peptides Using Recyclable Polymer-Supported Hydrogen Donor

Palladium catalyzed transfer hydrogenolysis of protected peptides using a recyclable polymer-supported formate as hydrogen donor affords pure hydrogenolyzed products without the need for any chromatographic purification steps and provides a facile method for the clean and efficient removal of some of the commonly used protecting groups in peptide synthesis.

Palladium-catalyzed simple and efficient hydrogenative cleavage of azo compounds using recyclable polymer-supported formate

Palladium-catalyzed room temperature transfer hydrogenation of azo compounds using recyclable polymer-supported formate as the hydrogen donor produces corresponding amine(s) in excellent yields (88%–98%). This method was found to be highly facile with selectivity over a number of other functional groups such as halogen, alkene, nitrile, carbonyl, amide, methoxy, and hydroxyl.Key words: azo compounds, catalytic transfer hydrogenation, polymer-supported formate, 10% Pd-C, amines.

Polymer-Supported Formate and Magnesium: An Efficient Transfer Hydrogenation System for the Facile Reduction of Azo Compounds

A mild and efficient method was developed for the chemo-selective reduction of azo compounds to the corresponding amine/s using recyclable polymer-supported formate as hydrogen donor in the presence of low cost magnesium powder at room temperature.

Simple and Efficient Reduction of Aromatic Nitro Compounds Using Recyclable Polymer-Supported Formate and Magnesium

Aromatic nitro compounds were chemoselectively reduced to the corresponding amines using recyclable polymer-supported formate as a hydrogen donor in the presence of low-cost magnesium powder at room temperature. Use of the immobilized hydrogen donor affords the product amine in excellent yield (90–97%) without the need for any chromatographic purification steps. This method was found to be highly facile with selectivity over several other functional groups, such as halogen, alkene, nitrile, carbonyl, ester, amide, methoxy, phenol, and hydroxyl groups.