Abstract Background University students turn to addictive substances to cope with the anxiety and stress caused by separation from family, adaptation to a new environment, as well as many economic and social problems. This study aimed to examine smoking, alcohol, substance, technology, and gambling addiction among university students. Methods The data of this cross-sectional study were collected between February and March 2024. The study population consisted of 23,446 people studying at Ä°nonu University, and the sample size was calculated as 346 based on a smoking rate of 35.6% among university students. A stratified sampling method was adopted according to the faculty of study, and 366 people were approached regarding the study. The independent variables were age, gender, faculty of study, and smoking status, while the dependent variables were alcohol and substance use status. Descriptive data were expressed in numbers and percentages, and a Chi-square test was used in the statistical analysis. Results Of the students in the research group, 56.8% were female, 54.4% were 22 years of age or older, 30.1% reported smoking cigarettes, 7.7% reported drinking alcohol in the last 30 days, 39.2% reported using the internet for five hours or more per day, 3% reported playing various casino games on the internet once a week or more, and 1.4% stated that they used substances. There was no statistically significant difference between alcohol and substance use according to smoking status (p > 0.05). Conclusions Approximately one-third of the students in the research group reported smoking cigarettes, and one-tenth reported alcohol use, which is quite high. The high percentage of students who use the internet for five hours or more per day and the low rate of online gambling should be considered in relation to these addictions. Key messages • Multidimensional interventions and intersectoral cooperation are required to prevent smoking, alcohol, substance use, technology, and gambling addictions among university students. • In addition, precautions should be taken to protect students against the risks associated with internet addiction and online gaming.
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