In this study, we explore the interrelation between hypergraph symmetries represented by equivalence relations on the vertex set and the spectra of operators associated with the hypergraph. We introduce the idea of equivalence relation compatible operators related to hypergraphs. Some eigenvalues and the corresponding eigenvectors can be computed directly from the equivalence classes of the equivalence relation. The other eigenvalues can be computed from a quotient operator obtained by identifying each equivalence class as an element. The equivalence classes of specific equivalence relations on the vertex set determine the structures of the hypergraph. We collectively classify them as building blocks of hypergraphs. For instance, an equivalence relation R s on the vertex set of a hypergraph is such that two vertices are R s -related if they belong to the same set of hyperedges. The R s -equivalence classes are named as units. Using units, we explore another symmetric substructure of hypergraphs called twin units. We show that these building blocks leave certain traces in the spectrum and the corresponding eigenspaces of the R s -compatible operators associated with the hypergraph. We also show that, conversely, some specific footprints in the spectrum and the corresponding eigenvectors retrace the presence of some of these building blocks in the hypergraph. Besides the spectra of R s -compatible operators, building blocks are also interrelated with hypergraph colouring, distances in hypergraphs, hypergraph automorphisms, and random walks on hypergraphs.