Quick Sequential Organ Failure Research Articles

Association of qSOFA with Ludwig's Angina Patient Mortality at Dr. Sutomo Hospital, Surabaya

Objective: This study aims to determine the association between The quick Sequential Organ Failure (qSOFA) score and the mortality of Ludwig's Angina. Material and Methods: Secondary data from the medical records of Ludwig’s Angina patients in the period January 2019 - December 2020. Data included demographic feature, qSOFA data, Outcome patient, comorbidity diseases and complications before treatment. The number of samples was determined using the total sampling method. This study was enrolled into analytical observational study. Results: There were 49 medical records that were included in the inclusion criteria, 6 medical records were excluded because the data were missing. There were more men 36 (73,5%) than women 13 (26,5%). There were 12 (24,5%) high qSOFA and 37 (75,5%) low qSOFA. There were 12 (24,5%) patient outcome dead and 37 (75,5%) outcome alive. The results of Chi-square analysis show qSOFA and confounding Diabetes Mellitus (DM) respectively were statistically significant association with Ludwig's Angina mortality. The results of multivariate logistic regression analysis, shows that there is a significant association between qSOFA and Ludwig's Angina mortality (p: 0.018) with an OR of 20.9 (CI 95% : 1,673 – 263,367). Diabetes mellitus comorbidity factors were also significantly associated with the mortality of Ludwig's angina. Conclusion: There is a significant association between qSOFA and Ludwig's Angina mortality. Keywords: Ludwig’s Angina, Mortality, qSOFA, Sepsis.

Association of qSOFA with Ludwig's Angina Patient Mortality at Dr. Sutomo Hospital, Surabaya

Objective: This study aims to determine the association between the quick Sequential Organ Failure (qSOFA) score and the mortality of Ludwig's Angina. Material and Methods: Secondary data from the medical records of Ludwig’s Angina patients in the period January 2019 - December 2020. Data included demographic feature, qSOFA data, Outcome patient, comorbidity diseases and complications before treatment. The number of samples was determined using the total sampling method. This study was enrolled into analytical observational study. Results: There were 49 medical records that were included in the inclusion criteria, 6 medical records were excluded because the data were missing. There were more men 36 (73,5%) than women 13 (26,5%). There were 12 (24,5%) high qSOFA and 37 (75,5%) low qSOFA. There were 12 (24,5%) patient outcome dead and 37 (75,5%) outcome alive. The results of Chi-square analysis show qSOFA and confounding Diabetes Mellitus (DM) respectively were statistically significant association with Ludwig's Angina mortality. The results of multivariate logistic regression analysis, shows that there is a significant association between qSOFA and Ludwig's Angina mortality (p: 0.018) with an OR of 20.9 (CI 95%: 1,673 – 263,367). Diabetes mellitus comorbidity factors were also significantly associated with the mortality of Ludwig's angina. Conclusion: There is a significant association between qSOFA and Ludwig's Angina mortality.

Current Evaluation of Sepsis among Patients with Liver Cirrhosis

Background and study aim: patients with liver cirrhosis have high incidence of sepsis. Spontaneous bacterial peritonitis and urinary tract infections are the most common infections among patients with livercirrhosis.New criteria including quick qSOFA and sepsis-3 criteria are used for diagnosing sepsis in patients with liver cirrhosis. These criteria appear to be more accurate than SIRS. The aim of this study is to evaluate the existing scoring systems in our patients with liver cirrhosis to identify patients with sepsis. Patients and Methods: This prospective study included 288 consecutive patients previously diagnosed to have liver cirrhosis and suspected to have bacterial/fungal infections. Quick Sequential (sepsis-related) organ failure assessment (qSOFA) criteria and sepsis-3 criteria were used to identify patients with organ dysfunction due to sepsis. Results: qSOFA and sepsis-3 criteria are more accurate than SIRS in detecting sepsis among patients with cirrhosis (The area under the receiver operating characteristic curve (AUROC) value for a model with qSOFA and sepsis-3 was AUROC: 0.77 and 0.76), while AUROC for SIRS was 0.66. Conclusion: Sepsis-3 and qSOFA are more accurate than SIRS criteria in early detection of sepsis among patients with cirrhosis. Patients with positive criteria need intensive management due to high risk of in-hospital mortality.

Su1248 - The Systemic Inflammatory Response Syndrome (SIRS) and Quick Sequential Organ Failure (qSOFA) Score At Presentation are Associated with Poor Outcomes in Acute Pancreatitis

Su1248 - The Systemic Inflammatory Response Syndrome (SIRS) and Quick Sequential Organ Failure (qSOFA) Score At Presentation are Associated with Poor Outcomes in Acute Pancreatitis