Quantum-dot-based single-molecule Förster resonance energy transfer for investigating the conformations of tau and phosphorylated tau.

Efficacy of InP/ZnSe/ZnS quantum dots with antibiotics in the treatment of multidrug-resistant Pseudomonas aeruginosa keratitis: Preclinical studies.

ZIF-67/Zn075Cd0.25S heterojunction for efficient photocatalytic hydrogen production: Lignin-carbon quantum dots synergistic enhanced charge separation and hydrogen diffusion.

Preparation and characterization of La/g-C3N4/TiO2 quantum dots and their detection of FLE-Induced degradation: A bifunctional study and its correlation with traditional Chinese medicine antitumor therapy applications

Amyloid β (Aβ) and α-synuclein (α-syn) have traditionally been recognized as the major causative proteins in Alzheimer's disease (AD) and Parkinson's disease (PD), respectively. However, AD and PD share many common pathogenic mechanisms and exhibit overlapping pathological features. Furthermore, multiple studies have reported the coexistence of Aβ and α-syn within the same pathological regions in individual patients, suggesting that such pathological coexistence is involved in disease progression and pathogenesis. However, the detailed mechanisms by which Aβ and α-syn influence each other and modulate their aggregation dynamics remain unclear. We previously established a method to observe the aggregation processes of Aβ and α-syn in two and three dimensions by utilizing the affinity between quantum dots (QDs) and amyloid aggregates, using fluorescence microscopy and confocal laser scanning microscopy. In this study, we used QD imaging, thioflavin T (ThT) fluorescence assays, and transmission electron microscopy (TEM) to evaluate in detail how Aβ42 and α-syn affect each other's aggregation behaviors. We found that 1 μM Aβ42 monomers did not affect the aggregation of 20 μM α-syn, whereas 1 μM Aβ42 oligomers significantly promoted 20 μM α-syn aggregation. In contrast, 1-10 μM α-syn inhibited the aggregation of 20 μM Aβ42 in a concentration-dependent manner, with α-syn polymers showing a stronger inhibitory effect than α-syn monomers. Taken together, these results demonstrate an asymmetry in their mutual effects on aggregation under the experimental conditions examined in this study: Aβ42 oligomers promote α-syn aggregation, whereas α-syn inhibits Aβ42 aggregation, particularly in its polymeric form.

Magnetic-order engineering enables substantial work function modulation: a charge transfer gating strategy in composite structure of antiferromagnet, quantum dots and topological insulator

An origami microfluidic paper-based analytical device for colorimetric determination of the albumin-creatinine ratio using Mn-ZnS quantum dots coated with molecularly imprinted polymers.

Turning waste into wealth: Conversion of spent plastic to carbon quantum dots to construct CQDs/g-C3N4 heterojunction for photocatalytic removal of antibiotics

Fluorescent carbon quantum dots from walnut green husk waste: Synthesis, characterization, and application in sustainable inkjet printing

Construction of S-scheme heterojunction dual-path photocatalytic hydrogen peroxide synthesis by covalent organic frameworks loaded with AgInS2 quantum dots.

Direct observation of Mirror-Twin-Boundaries in WS2 quantum dots via HRTEM imaging

Fluorescent molecularly imprinted sensor for rapid detection of gentamicin in Milk.

Exploring the molecular interaction between tryptophan and β-cyclodextrin modified ZnS quantum dots using spectroscopic analysis.

Synergistic triple π-conjugated ligand exchange strategy for high-performance perovskite quantum dot light-emitting diodes

Superhydrophilic polyimide/carbon quantum dots aerogels for superior visible-light photocatalysis and water evaporation

Fluorine-doped carbon quantum dots for sunset yellow analysis in complex food matrices

Highly conductive ligands resurfacing perovskite quantum dots boost the efficiency of light-emitting diodes

Soybean-residue carbon carbon quantum dots as corrosion inhibitor for copper‑nickel alloy in H2SO4 medium

Engineered CdS@ZIF67 nanozyme-assisted detection of vitamin D deficiency.

Sesame straw-based self-doped carbon quantum dots as green inhibitors for AZ31 magnesium alloy in 3.5% sodium chloride solution