The study aims to present a complicated clinical case of a woman who almost died due to comorbid obstetric pathology associated with a coronavirus infection. The term “near miss” refers to the detailed analysis of each clinical case classified as a critical obstetric condition, as well as the registration of patients with such conditions in the Russian register established in 2021 to prevent maternal mortality and make management decisions. A severe clinical near miss case of a female patient included the following serious obstetric syndromes: postpartum obstetric hemorrhage followed by uterine artery embolization, endomyometritis by the third day, partial thrombosis of the branches of the right lower lobe pulmonary artery by the seventh day, thrombosis of parametrial vessels, partial necrosis of the uterus by the eighth day, and a new coronavirus infection COVID-19 by the thirteenth day after delivery. The complexity of diagnosis and treatment is demonstrated in the results of the study in the acute period and in the outcome of the disease.