Hormonal shifts during the menstrual cycle (MC) cause autonomic imbalances and psycho-physiological distress in eumenorrheic females. This present study reveals that yoga proactively improves the overall psychophysiological health and wellness in eumenorrheic female college students during different phases of MC. Healthy eumenorrheic female college students (Mage= 20.11 ± 5.39 years, n = 82) were randomized to a control and yoga group (n = 41). A well-conceptualized yoga module (CYM) for 5 days/week for 3 months (1h daily in the morning) was practiced by the yoga group volunteers. Intra and intergroup comparisons were performed for the estimation of mindfulness awareness scale (MAAS), menstrual distress questionnaire (MDQ), cardiometabolic risk factors, heart rate variability (HRV), and endurance fitness during the luteal (LP) and follicular (FP) phases. Psychophysiological discomforts before CYM practice were mostly observed during LP compared to FP due to significant changes in mindfulness, pain, concentration, autonomic reactivity, negative affect, double product (DoP), rate pressure product (RPP), and HRV values. CYM practice influenced HRV parameters for an increase in parasympathetic activity and a decrease in sympathetic balance for better cardiac-autonomic functioning, with significant improvement in maximal oxygen consumption (VO2max) and physical work capacity (PWC170). Accordingly, MAAS and MDQ scores also improved significantly after yogic practice. The intra-group and inter-group significant improvements in psychophysiological parameters through CYM practice are relevant in eumenorrheic females to perform effectively throughout their MC period, by improving MC distress and sympathovagal (LF/HF) balance.

Does anti-Black racism harm White Americans? We advance hypotheses that address this question within the neighborhood context. Hypotheses are tested with neighborhood and survey data from a probability sample of White residents of Nashville, Tennessee. We find that regardless of neighborhood crime rates or socioeconomic compositions, Whites report heightened perceptions of crime and danger in their neighborhoods as the proportion of Black residents increases. Perceived neighborhood danger, in turn, predicts increased symptoms of psychophysiological distress. When stratified by socioeconomic status (SES), however, low-SES Whites also report perceptions of higher status when living near more Black neighbors, which entirely offsets their distress. We conclude that although anti-Black racism can ironically harm the health of White Americans, compensatory racist ideologies can also offset these harms, particularly for lower-status Whites. We situate our findings within broader discussions of anti-Black racism, residential segregation, and psychiatric disorders commonly observed among White Americans.

Global neuropsychological impairments with intellectual disability (ID) seem to play a major role in the occurrence of psychogenic non‐epileptic seizures (PNES) in epilepsy. Conversely, the pathophysiology underlying PNES combined with epilepsy without ID remains elusive. We investigated the neuropsychiatric profile in 26 average intelligent subjects (15 women, mean age: 40.04 ± 13.53 years) with temporal lobe epilepsy (TLE) plus PNES (TLE + PNES), compared with 28 with TLE and 22 with PNES alone, matched for age and sex. All subjects underwent neuropsychiatric assessment, including Beck Depression Inventory‐2 (BDI‐2), State‐Trait Anxiety Inventory (STAI), Dissociative Experiences Scale (DES), Toronto Alexithymia Scale (TAS‐20), Traumatic Experience Checklist (TEC), and cognitive evaluation. TLE + PNES and PNES groups shared a similar psychiatric profile with higher levels of depression (BDI‐2, P < 0.001), anxiety (STAI‐S, P < 0.001; STAI‐T, P < 0.001), dissociation (DES, P < 0.001), and alexithymia (TAS, P = 0.005) scales than the TLE group. Nonetheless, like individuals with TLE, patients with TLE + PNES had a lower rate of a potentially traumatizing event than PNES. The very low rate of potentially traumatizing event in subjects with TLE + PNES leads us to hypothesize that epilepsy itself may be the psychophysiological distress that contributed to PNES. A psychopathological assessment in subjects with epilepsy is crucial to identify those more likely to develop PNES.

I am feeling stressed, are you?: Breast cancer patients and caregivers' inter-psychophysiological symptoms during the first year of breast cancer treatment

This article contributes to the quality of life literature by investigating gender and age gaps in psycho-physiological distress during the COVID-19 pandemic in Italy. Specifically, we investigate whether women experienced higher levels of distress than men, and if such gap can be explained by a greater negative reaction of women in the experience of a negative COVID-19 related event, such as the illness or death of a relative. Moreover, we explore whether age moderated or amplified the effect of a negative event on distress among women and men. To do so we rely on an ad hoc survey carried out between April 2020 and June 2021 in Italy, the first European country to be hit by the pandemic. Our results indicate that subjects who experienced the hospitalization or, more so, the death of a family member during the pandemic were more exposed to psycho-psychological distress compared to subjects who were not directly touched by COVID-19. Moreover, our results show that while women were on average more likely to express feelings of distress than men in absence of evident stressors, this gap disappeared among subjects who experience the death of a relative. Furthermore, our results indicate that experiencing a negative COVID-19 related event led to an increase in distress among all respondents except older men, who appeared to be the most resilient to the manifestation of any sign of distress. These results speak to important age and gender differences in the feelings and externalization of grief in the Italian context.

(1) Background: Functional Hypothalamic Amenorrhea (FHA) can be caused by the hyper activation of neuro-endocrine responses to stress. Among other endocrine factors and hypothalamic dysfunctions, the psychophysiological stress response can very frequently lead to an inhibition of the gonadal–pituitary axis. The aim of this study was to investigate the level of neurovegetative activation in a group of young women affected by this condition. (2) Methods: Twenty-five women (mean age = 21.1 ± 4.34) with FHA were consecutively recruited. Information on psycho-physiological distress was collected through a Psychopathological assessment (with the administration of three psychometric tests) and the Psychophysiological Stress Profile (PSP). Their data were compared with a control group. (3) Results: In the PSP, the patients displayed significantly higher values compared to controls in terms of the parameters of muscle tension (sEMG), skin conductance (SCL/SCR), heart rate (HR), and peripheral temperature (PT). Furthermore, autonomic hyper-activation at rest, marked reactivity to stress, and reduced recovery were seen. Moreover, a condition characterized by psychological distress (anxiety and somatic complaints, depressed and irritable mood, obsessive-compulsive traits) emerged. (4) Conclusions: The results highlight autonomic hyper-activation in FHA, which is also associated with psychological distress. Considering that FHA is a condition that affects multiple systems between mind and body, a multimodal, multidimensional, and multidisciplinary assessment of stress is becoming an emerging need.

Breast cancer patients and caregivers experience biobehavioral reactivity (e.g., depression, anxiety, pain, fatigue) during breast cancer treatment which predicts cancer recurrence and mortality. High quality patient-caregiver relationships can mitigate this distress during treatment, but this association is unclear pre-treatment. Identifying early interventions that target high risk Appalachian patients could impact biobehavioral reactivity. We recruited 55 breast cancer patient-caregiver dyads to complete a self-report survey after diagnosis but before treatment. We used a series of Actor-Partner Interdependence Models to test the hypotheses that both patient and caregiver relationship quality would be linked to their own and their partners' biobehavioral reactivity. Caregiver reported marital quality lower caregiver anxiety, patient anxiety, caregiver depression, patient depression, caregiver pain, and caregiver fatigue. Interestingly, patient-reported marital quality was linked with higher caregiver anxiety, higher patient anxiety, lower patient depression, and lower patient pain. Patients reported family quality was linked to lower patient and caregiver pain. This study demonstrates that pre-treatment marital and family quality levels are directly related to psychophysiological measures in both the caregiver and the patient, though sometimes in unexpected directions. Additionally, our findings potentially reveal an opportunity to intervene at the time of diagnosis to improve relationship quality, impacting patient and caregiver psychophysiological outcomes.

ABSTRACT There has been a growing interest in understanding the interdependencies between urbanisation and mental health. Although transportation in cities is complex and of foremost importance to support the mobility of goods and passengers, little is known about how it relates to individual psychological distress. This review aims to provide an up-to-date synthesis of research evidence about the influence of transport infrastructure and operational performance (congestion, delays and reliability) on mental health/wellbeing. It is structured around three main interacting concepts that determined the search/selection of articles: identification of the above-mentioned transport-related exposures; use of psychological and physiological validated instruments; and the outcome on mental health/wellbeing. Ultimately, 69 studies were identified involving an empirical quantitative focus that met the inclusion criteria. We summarise the instruments most reported in these studies and the findings linking transport indicators and psychological and physiological outcomes. Across the review, we identified evidence of the contribution of key transport infrastructure, congestion and delay indicators on negative affective states and psychophysiological distress. Regarding transport reliability, the scarce number of studies identified did not allow for drawing similar firm conclusions. We conclude by discussing some limitations and providing recommendations for future research and policy-making agendas.

Perceived discrimination is a significant risk factor for worse ageing health outcomes. Yet, the specific individual and relational stress pathways linking discrimination to disease are less understood, especially in the context of cardiometabolic health. We tested family stress and psychophysiological distress (negative affect and high-risk lipid/fat metabolism) as mediators linking perceived discrimination to cardiometabolic morbidity and health appraisal over 20years for midlife adults. Using data from participants who completed the Biomarker Project (2004-2009) of the Midlife in the U.S. project, and examining data over the study's three waves (1995-1996, 2004-2006, and 2013-2014), we used structural equation modelling to test pathways for participants who reported zero cardiometabolic conditions at baseline (n=799). Greater Time 1 discrimination was associated with greater Time 2 family strain, which was in turn associated with worse negative affect; worse Time 2 negative affect was associated with worse Time 3 health appraisal; metabolic lipids risk did not serve as an indirect pathway to Time 3 cardiometabolic morbidity (χ2 =147.74, p<0.001; RMSEA=0.056; CFI=0.902; SRMR=0.047). The inclusion of family in interventions to mitigate the impact of discrimination may be indicated for promoting cardiometabolic wellness.

ObjectivesSchools are experiencing an unprecedented mental health crisis, with teachers reporting high levels of stress and burnout, which has adverse consequences to their mental and physical health. Addressing mental and physical health problems and promoting wellbeing in educational settings is thus a global priority. This study investigated the feasibility and effectiveness of an 8-week Compassionate Mind Training program for Teachers (CMT-T) on indicators of psychological and physiological wellbeing.MethodsA pragmatic randomized controlled study with a stepped-wedge design was conducted in a sample of 155 public school teachers, who were randomized to CMT-T (n = 80) or a waitlist control group (WLC; n = 75). Participants completed self-report measures of psychological distress, burnout, overall and professional wellbeing, compassion and self-criticism at baseline, post-intervention, and 3-months follow-up. In a sub-sample (CMT-T, n = 51; WLC n = 36) resting heart-rate variability (HRV) was measured at baseline and post-intervention.ResultsCMT-T was feasible and effective. Compared to the WLC, the CMT-T group showed improvements in self-compassion, compassion to others, positive affect, and HRV as well as reductions in fears of compassion, anxiety and depression. WLC participants who received CMT-T revealed additional improvements in compassion for others and from others, and satisfaction with professional life, along with decreases in burnout and stress. Teachers scoring higher in self-criticism at baseline revealed greater improvements post CMT-T. At 3-month follow-up improvements were retained.ConclusionsCMT-T shows promise as a compassion-focused intervention for enhancing compassion, wellbeing and reducing psychophysiological distress in teachers, contributing to nurturing compassionate, prosocial and resilient educational environments. Given its favourable and sustainable effects on wellbeing and psychophysiological distress, and low cost to deliver, broader implementation and dissemination of CMT-T is encouraged.

The article examines the negative childhood experience and its relationship with psychophysiological distress in early adulthood. Special attention is paid to approaches to the study of negative children’s experience in domestic and foreign literature. The data of an empirical study of the problem are presented.

Precisely timed production of dexterous actions is often destabilized in anxiogenic situations. Previous studies demonstrated that cognitive functions such as attention and working memory as well as autonomic nervous functions are susceptible to psychological stress in skillful performance while playing sports or musical instruments. However, it is not known whether the degradation of sensorimotor functions underlies such a compromise of skillful performance due to psychophysiological distress. Here, we addressed this issue through a set of behavioral experiments. After artificially delaying the timing of tone production while playing the piano, the local tempo was abnormally disrupted only under pressure. The results suggest that psychological stress degraded the temporal stability of movement control due to an abnormal increase in feedback gain. A learning experiment further demonstrated that the temporal instability of auditory-motor control under pressure was alleviated after practicing piano while ignoring delayed auditory feedback but not after practicing while compensating for the delayed feedback. Together, these findings suggest an abnormal transition from feedforward to feedback control in expert piano performance with psychological stress, which can be mitigated through specialized sensorimotor training that involves piano practice while volitionally ignoring the artificially delayed provision of auditory feedback.

Modern education is characterized by the variability of forms and requirements, which necessitates the search for the ways of effective academic adaptation of students. The purpose of this study is to study and experimentally confirm the component structure of academic adaptation at primary school age. The study involved 80 primary schoolchildren of the municipal educational institution "Secondary school No. 59" in Saratov (RF) and 51 parents. To study the component structure of the academic adaptation, the authors' questionnaire and scales for parents and children were used to assess the motivational, emotional, cognitive, communicative, personal (regulatory), as well as psychophysiological components of academic adaptation. New scientific data were obtained on the relationship of the motivational component of academic adaptation (with cognitive r= 0.245, at p &lt; 0.05), cognitive (with internal learning motivation, r= 0.529, at p &lt;0.01), and personal (with cognitive r= 0.375, at p&lt; 0.01). It was found that the most variable characteristic of the academic adaptation of primary schoolchildren is the arbitrariness of mental processes (σ = 0.9). As a result of factor analysis, 7 factors of academic adaptation were identified: "Consistency of self-esteem as a good student", "Orientation towards independence in studies and communication with peers", "Psychophysiological distress", "Avoiding school troubles based on emotional self-regulation and thinking through actions at school", "Striving to improve normative behavior at school", "Social success in school", "General emotional well-being at school". It is also shown that, in the views of parents, the mental stress of students is a positive factor in the academic adaptation of their children, while the students themselves experience a negative influence of this factor on the success of their adaptation. The results of the experimental study enabled to create the scientific basis for developing a technology of psychological and pedagogical support for the academic adaptation of primary school students, contributing to the successful inclusion of a child in the educational environment.

Control of technological processes is becoming increasingly more complex in nature. The operator has to respond to a large number of signals and quickly make correct decisions. The use of automatic control systems cannot solve this problem to a full extent. There is always a risk that they can fail and produce inadequate commands; therefore, the operation of automatic systems is also monitored by a human. Control of complex technological processes comes in contradiction with the psychophysiological capabilities of a human organism. In many cases, this problem is solved by selecting, for the role of operators, people having special capabilities, who can quickly make the correct decision in a critical situation. However, work under such conditions entails the extremely high tension of their nervous systems. As a result, the operators regularly suffer from distress, which has a destructive impact on the human health and gives rise to many dangerous diseases. In addition, distress eventually causes the operator to lose his or her ability to quickly and adequately respond to the occurrence of a critical situation. This phenomenon is called the job burnout syndrome. At the initial phase of its development, this syndrome cannot be revealed even during regular tests of operators. Diagnostics of this syndrome also encounters difficulties as the personnel strive to conceal loss of their professional abilities. It should be noted that the consequences of destructive psychophysiological distress conditions manifest themselves to a full extent exactly in critical situations, i.e., under the conditions of maximum stress on the organism. This is why the majority of large-scale industrial disasters are caused by a human error or a human factor. Thus, selection of the operators having extraordinary abilities cannot ensure safety of technological processes. An alternative method for solving this problem is introduction of a systematic labor protection concept. Its priority aim is to create a working environment, the staying in which for a long period of time does not have a negative impact on the vital functions of the operator’s organism. Under these conditions, the risk of industrial accidents caused by a human factor can be minimized.

BackgroundThe lack of a holistic approach to palliative care can lead to a fractured sense of dignity at the end of life, resulting in depression, hopelessness, feelings of being a burden to others, and the loss of the will to live among terminally ill patients. Building on the clinical foundation of Dignity Therapy, together with the empirical understanding of dignity-related concerns of Asian families facing terminal illness, a novel Family Dignity Intervention (FDI) has been developed for Asian palliative care. FDI comprises a recorded interview with a patient and their primary family caregiver, which is transcribed, edited into a legacy document, and returned to the dyads for sharing with the rest of the patient’s family. The aims of this study are to assess the feasibility, acceptability and potential effectiveness of FDI in reducing psychosocial, emotional, spiritual, and psychophysiological distress in community-dwelling and in-patient, Asian, older terminally ill patients and their families living in Singapore.Methods/designAn open-label randomized controlled trial. One hundred and twenty-six patient-family dyads are randomly allocated to one of two groups: (1) an intervention group (FDI offered in addition to standard psychological care) and (2) a control group (standard psychological care). Both quantitative and qualitative outcomes are assessed in face-to-face interviews at baseline, 3 days and 2 weeks after intervention, as well as during an exit interview with family caregivers at 2 months post bereavement. Primary outcome measures include sense of dignity for patients and psychological distress for caregivers. Secondary outcomes include meaning in life, quality of life, spirituality, hopefulness, perceived support, and psychophysiological wellbeing, as well as bereavement outcomes for caregivers. Qualitative data are analyzed using the Framework method.DiscussionTo date, there is no available palliative care intervention for dignity enhancement in Asia. This first-of-its-kind study develops and tests an evidence-based, family driven, psycho-socio-spiritual intervention for enhancing dignity and wellbeing among Asian patients and families facing mortality. It addresses a critical gap in the provision of holistic palliative care. The expected outcomes will contribute to advancements in both theories and practices of palliative care for Singapore and its neighboring regions while serving to inform similar developments in other Asian communities.Trial registrationClinicalTrials.gov, ID: NCT03200730. Registered on 26 June 2017.

This study used data from 63 heterosexual couples to investigate the effects of attachment anxiety and how they relate to emotional experience (i.e. psychophysiological distress and feelings towards a partner) in the context of two therapy‐like conditions (low and high structure). We examined both the effect of an individual's anxiety on his/her own emotional experience (actor effects) and on the partner's experience (partner effects). During both interactional conditions, female partners of men higher in attachment anxiety experienced greater psychophysiological distress. In addition, men and women higher in attachment anxiety were not significantly different from others in terms of their feelings towards their partner during the low structure condition. However, their feelings were significantly more positive than others during the high structure condition, providing some evidence that attachment‐based interventions can be especially useful for clients higher in attachment anxiety.Practitioner points Not only should therapists take into account couple distress and volatility when facilitating couple interaction, but they should also account for self‐reported attachment Clients high in attachment anxiety may benefit from the emotional containment provided by having a therapist buffer the couple interaction Clients high in attachment anxiety may especially benefit from therapy process that is anchored in facilitating attachment‐based expression

Effects of Anxiety on Spontaneous Ritualized Behavior

Adults with autism spectrum disorder (ASD) face substantial challenges accomplishing basic tasks associated with daily living, which are exacerbated by their broad and pervasive difficulties with social interactions. These challenges put people with ASD at increased risk for psychophysiological distress, which likely factors heavily into social functioning for adults with ASD, as suggested by a growing literature on stress in children that indicates that children with ASD have differential responses to stress than healthy children. We hypothesized that adults with ASD and without intellectual disability (n = 38) would experience more stress than healthy volunteers (n = 37) and that there would be an inverse relationship between stress and social functioning in individuals with ASD. Baseline, semi-structured interview data from a randomized controlled trial of two treatments for adults with ASD were used to assess differences in stress between adults with ASD and healthy volunteers and to assess the relationship between stress response and social functioning in adults with ASD. Findings indicate that adults with ASD experience greater perceived and interviewer-observed stress than healthy volunteers and that stress is significantly related to social functioning in adults with ASD. These findings highlight the role of stress in adult functioning and outcomes and suggest the need to develop and assess treatments designed to target stress and coping in adults with ASD.

Attachment strategies refer to the conscious representations individuals make of their relationships, including the level of perceived comfort and safety that relationships offer during distressing times. From early in life, some individuals learn the coping strategy of attachment avoidance. When distressed, these individuals shut down emotionally and seek to mask what they are feeling. This represents incongruence between emotional experience and expression. Yet congruence is an important part of interpersonal relationships. In addition, incongruence has been identified as a core aspect of repressive coping, about which research has identified several potential long-term health risks. In this study, we examined the relationship between attachment avoidance and congruence between what individuals experience physiologically and what they report. A total of 63 couples completed the Experiences in Close Relationships Scale (ECR; Brennan, Clark, & Shaver, 1998) and participated in a seminatural couple interaction and an interaction with a therapist/coach. Using dyadic data analysis and multilevel modeling, we found that, while avoidance was not associated with elevated skin conductance, it was indeed associated with greater incongruence between skin conductance and reports of feelings toward one's partner. Whereas individuals lower in attachment avoidance were likely to report more negative feelings toward their partners in the context of psychophysiological distress, those higher in attachment avoidance were more likely to report positive feelings toward their partners. We discuss implications of this incongruence and its potential to adversely influence individual and relationship health. We also discuss some important clinical considerations when working to increase emotional congruence.

Occupational stress is a multivariate process involving sources of pressure, psycho-physiological distress, locus of control, work dissatisfaction, depression, anxiety, mental health disorders, hopelessness, and suicide ideation. Healthcare professionals are known for higher rates of occupational-related distress (burnout and compassion fatigue) and higher rates of suicide. The purpose of this study was to explain the relationships between occupational stress and some psychopathological dimensions in a sample of health professionals. We investigated 156 nurses and physicians, 62 males and 94 females, who were administered self-report questionnaires to assess occupational stress [occupational stress inventory (OSI)], temperament (temperament evaluation of Memphis, Pisa, Paris, and San Diego autoquestionnaire), and hopelessness (Beck hopelessness scale). The best Multiple Indicators Multiple Causes model with five OSI predictors yielded the following results: χ2(9) = 14.47 (p = 0.11); χ2/df = 1.60; comparative fit index = 0.99; root mean square error of approximation = 0.05. This model provided a good fit to the empirical data, showing a strong direct influence of casual variables such as work dissatisfaction, absence of type A behavior, and especially external locus of control, psychological and physiological distress on latent variable psychopathology. Occupational stress is in a complex relationship with temperament and hopelessness and also common among healthcare professionals.