You have accessJournal of UrologyTrauma/Reconstruction: Ureter, Bladder, External Genitalia and Urotrauma I1 Apr 2015MP18-09 IATROGENIC GENITOURINARY INJURIES DURING COLORECTAL SURGERY: CHARACTERIZATION AND LONG-TERM OUTCOMES Valary T. Raup, Jairam R. Eswara, and Steven B. Brandes Valary T. RaupValary T. Raup More articles by this author , Jairam R. EswaraJairam R. Eswara More articles by this author , and Steven B. BrandesSteven B. Brandes More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2015.02.1041AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Little is known about the rates of iatrogenic genitourinary (GU) complications that occur during colorectal surgery, nor is there data regarding the long-term outcomes of these GU repairs. The purpose of this study is to quantify and categorize these injuries and analyze their long-term outcomes, with special attention to patients who have undergone pre-operative chemotherapy and or/pelvic radiation. METHODS We performed a retrospective analysis of patients who developed iatrogenic GU injuries requiring surgical repair during colorectal surgery between 2003 and 2013. Repair failures were defined as development of urine leak/urinary fistula requiring repeat GU intervention. Possible risk factors associated with repair failures were examined, such as age, ASA score, comorbidities, type of colorectal surgery, and prior radiation or chemotherapy. RESULTS There were 75 patients in this series, with a mean age of 57.5 years (22–91) at time of surgery and median follow up of 16.7 months (0–127). GU injuries occurred most frequently in lower abdominal resections (21), colectomies (16), colonic resections with concurrent total abdominal hysterectomies and bilateral salpingo-oophorectomies (13), and abdominoperineal resections (9). The most common initial GU repairs were cystorrhaphy (26), ureteroureterostomy (22), ureteroneocystotomy with psoas hitch (13), and ureteroneocystotomy without psoas hitch (11). Sixty-four patients had single GU repairs and 16 patients experienced failure of their initial repair with need for additional GU intervention. Of the patients who had undergone pre-operative pelvic radiation, 11/27 (41%) experienced failure of their GU repair, versus 5/48 (10%) that had not been previously irradiated (p=0.003). Pre-operative chemotherapy as also shown to be associated with GU repair failure (12/35 vs. 4/40, p=0.013). Fifty patients (67%) were alive at time of final follow-up, with a 30-day mortality rate of 4%. CONCLUSIONS Pre-operative radiation and chemotherapy are associated with worse outcomes of GU repairs following GU injury during colorectal surgery. Further studies are required to assess potential benefit in postponing more complex GU repairs with interval temporary urinary diversion until peri-operative inflammation has had a chance to subside. © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 193Issue 4SApril 2015Page: e208-e209 Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.MetricsAuthor Information Valary T. Raup More articles by this author Jairam R. Eswara More articles by this author Steven B. Brandes More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...
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